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The map label for this gene is lysS [H]

Identifier: 238028012

GI number: 238028012

Start: 2797266

End: 2798792

Strand: Direct

Name: lysS [H]

Synonym: bglu_1g24620

Alternate gene names: 238028012

Gene position: 2797266-2798792 (Clockwise)

Preceding gene: 238028011

Following gene: 238028013

Centisome position: 71.61

GC content: 66.93

Gene sequence:

>1527_bases
ATGACCGAACCGACCCAACCGCAGGCCGCGCCCGCGACCGACGAAAACCAGATCATCGCCGAGCGCCGCGAAAAGCTGCG
CGCGCTGCGCGAGCAAGGCATCGCCTACCCGAACGACTTCCAGCCCACGCACCACGCGGCCGACCTGCAGTCGACCTACG
CAGATGCCGACAAGGAGGCGCTCGAAGCGCAGCCGCTCGAGGTCCGGCTCGCGGGCCGGATGATGCTCAAGCGCGTGATG
GGCAAGGCGAGCTTCGCGACCGTGCAGGACGGCTCGGGCCAGATCCAGTTCTTCGTGACGCCGGCCGACGTCGGCGCCGA
GACCTACGATGCGTTCAAGAAGTGGGACCTCGGCGACATCGTCGCCGCACGCGGCGTGCTGTTCCGCACCAACAAGGGCG
AGCTGTCGGTCAAGTGCAGCGAGCTGCGGCTGCTGTCGAAGGCGCTGCGCCCGCTGCCGGACAAGTTCCACGGCCTGGCG
GACCAGGAGATGCGCTATCGGCAGCGCTACGTCGACCTGATCGTCACGCCCGAGACGCGCAACACCTTCCGCGCGCGCAC
CAAGGCGATCGCGTCGATCCGCAAGTTCATGAGCGACGCCGAGTTCATGGAAGTCGAGACGCCGATGCTGCATCCGATCC
CGGGCGGCGCGGCCGCCAAGCCGTTCATCACGCATCACAACGCGCTCGACATGCAGATGTTCCTGCGCATCGCCCCGGAG
CTGTACCTGAAGCGCCTGATCGTCGGCGGCTTCGAGCGCGTGTTCGAAATCAACCGGAATTTCCGTAACGAGGGCGTCTC
GCCGCGCCACAATCCGGAATTCACGATGATGGAGTTCTATGCCGCCTACACCGACTACCGCTGGCTGATGGACTTCACCG
AGCAGCTGATCCGCCAGGCCGCGATCGACGCGCTCGGCACCGCCACGATCCAGTACCAGGGCCGCGAGCTCGATCTCGCC
AGGCCGTTTCACCGCCTCACGATCACGCAGGCGATCCAGAAGTACGCCCCCGGCTACGGCGACGCGCAGCTCGCCGATCC
GGCCTTCCTGCGCACCGAACTGAAGCGCTTCGGCGTGGACGTGGGCCAGCCCGCGTTCCTGAACGCCGGGCTCGGCGCGC
TGCAGCTCGCGCTGTTCGAGGAAACCGCCGAGTCGCAGCTGTGGGAGCCGACCTACATCATCGACTACCCGGTCGAGGTC
TCGCCGCTCGCGCGCGCCTCCGACACGGTGCCCGGCATCACCGAGCGCTTCGAGCTGTTCATGACGGGCCGCGAGATCGC
CAACGGCTTCTCGGAGCTCAACGACCCGGAAGACCAGGCCGCGCGCTTCAAGAAGCAGGTCGAGCAGAAGGACGCCGGCG
ACGAGGAAGCGATGTTCTTCGACGCCGACTATATCCGCGCGCTCGAATACGGCATGCCGCCGACGGGCGGCTGCGGGATC
GGCATCGACCGCCTCGTGATGCTGCTGACCGACAGCCCGACGATTCGAGACGTGCTGCTGTTCCCGCATTTGCGCCGCGA
GGACTGA

Upstream 100 bases:

>100_bases
GCCGGCGCCGCAAGCGGCGTGCGGCATGCCAGGCAGCGGCCCGCGCCGCCGCTGCCTGGCTGCACGCCGCACCCGAGTTA
CCCATCGAATTCCGACCATC

Downstream 100 bases:

>100_bases
GGCGCGGCCGCCGGATCGCTCGCGCAGCTGCGGCGCGCGATCCGGCAGCAGGAGCCGGCCGTCCCGCAACACGTTCGAAA
GCTTTGTAACGGCGCGTAAA

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MTEPTQPQAAPATDENQIIAERREKLRALREQGIAYPNDFQPTHHAADLQSTYADADKEALEAQPLEVRLAGRMMLKRVM
GKASFATVQDGSGQIQFFVTPADVGAETYDAFKKWDLGDIVAARGVLFRTNKGELSVKCSELRLLSKALRPLPDKFHGLA
DQEMRYRQRYVDLIVTPETRNTFRARTKAIASIRKFMSDAEFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFLRIAPE
LYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLA
RPFHRLTITQAIQKYAPGYGDAQLADPAFLRTELKRFGVDVGQPAFLNAGLGALQLALFEETAESQLWEPTYIIDYPVEV
SPLARASDTVPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGI
GIDRLVMLLTDSPTIRDVLLFPHLRRED

Sequences:

>Translated_508_residues
MTEPTQPQAAPATDENQIIAERREKLRALREQGIAYPNDFQPTHHAADLQSTYADADKEALEAQPLEVRLAGRMMLKRVM
GKASFATVQDGSGQIQFFVTPADVGAETYDAFKKWDLGDIVAARGVLFRTNKGELSVKCSELRLLSKALRPLPDKFHGLA
DQEMRYRQRYVDLIVTPETRNTFRARTKAIASIRKFMSDAEFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFLRIAPE
LYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLA
RPFHRLTITQAIQKYAPGYGDAQLADPAFLRTELKRFGVDVGQPAFLNAGLGALQLALFEETAESQLWEPTYIIDYPVEV
SPLARASDTVPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGI
GIDRLVMLLTDSPTIRDVLLFPHLRRED
>Mature_507_residues
TEPTQPQAAPATDENQIIAERREKLRALREQGIAYPNDFQPTHHAADLQSTYADADKEALEAQPLEVRLAGRMMLKRVMG
KASFATVQDGSGQIQFFVTPADVGAETYDAFKKWDLGDIVAARGVLFRTNKGELSVKCSELRLLSKALRPLPDKFHGLAD
QEMRYRQRYVDLIVTPETRNTFRARTKAIASIRKFMSDAEFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFLRIAPEL
YLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQAAIDALGTATIQYQGRELDLAR
PFHRLTITQAIQKYAPGYGDAQLADPAFLRTELKRFGVDVGQPAFLNAGLGALQLALFEETAESQLWEPTYIIDYPVEVS
PLARASDTVPGITERFELFMTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGIG
IDRLVMLLTDSPTIRDVLLFPHLRRED

Specific function: Unknown

COG id: COG1190

COG function: function code J; Lysyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI5031815, Length=513, Percent_Identity=39.9610136452242, Blast_Score=351, Evalue=9e-97,
Organism=Homo sapiens, GI194272210, Length=513, Percent_Identity=39.9610136452242, Blast_Score=350, Evalue=1e-96,
Organism=Homo sapiens, GI40789249, Length=330, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789256, Length=506, Percent_Identity=58.300395256917, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1790571, Length=506, Percent_Identity=57.5098814229249, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI87082379, Length=326, Percent_Identity=31.2883435582822, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788173, Length=250, Percent_Identity=26.8, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=529, Percent_Identity=41.2098298676749, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17535927, Length=529, Percent_Identity=41.2098298676749, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71994340, Length=496, Percent_Identity=42.5403225806452, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17551876, Length=356, Percent_Identity=23.876404494382, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32566633, Length=210, Percent_Identity=26.1904761904762, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320242, Length=519, Percent_Identity=41.8111753371869, Blast_Score=364, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6324256, Length=558, Percent_Identity=31.0035842293907, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24640849, Length=529, Percent_Identity=39.3194706994329, Blast_Score=360, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24640851, Length=529, Percent_Identity=39.3194706994329, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24584738, Length=359, Percent_Identity=25.9052924791086, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR002313
- InterPro:   IPR018149
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 57434; Mature: 57303

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPTQPQAAPATDENQIIAERREKLRALREQGIAYPNDFQPTHHAADLQSTYADADKEA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHH
LEAQPLEVRLAGRMMLKRVMGKASFATVQDGSGQIQFFVTPADVGAETYDAFKKWDLGDI
HCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECHHCCHHHHHHHHCCCHHHH
VAARGVLFRTNKGELSVKCSELRLLSKALRPLPDKFHGLADQEMRYRQRYVDLIVTPETR
HHHCCEEEECCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHEEEEECCCCC
NTFRARTKAIASIRKFMSDAEFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFLRIAPE
HHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
LYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDALGTATIQYQGRELDLARPFHRLTITQAIQKYAPGYGDAQLADPAFLRTELKRFGVD
HHHHHCCEEEEECCCEECHHCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
VGQPAFLNAGLGALQLALFEETAESQLWEPTYIIDYPVEVSPLARASDTVPGITERFELF
CCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCCHHHHHHHH
MTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCCCCCC
GIDRLVMLLTDSPTIRDVLLFPHLRRED
CHHHHHHHHCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEPTQPQAAPATDENQIIAERREKLRALREQGIAYPNDFQPTHHAADLQSTYADADKEA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCHHH
LEAQPLEVRLAGRMMLKRVMGKASFATVQDGSGQIQFFVTPADVGAETYDAFKKWDLGDI
HCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECHHCCHHHHHHHHCCCHHHH
VAARGVLFRTNKGELSVKCSELRLLSKALRPLPDKFHGLADQEMRYRQRYVDLIVTPETR
HHHCCEEEECCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHEEEEECCCCC
NTFRARTKAIASIRKFMSDAEFMEVETPMLHPIPGGAAAKPFITHHNALDMQMFLRIAPE
HHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHH
LYLKRLIVGGFERVFEINRNFRNEGVSPRHNPEFTMMEFYAAYTDYRWLMDFTEQLIRQA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIDALGTATIQYQGRELDLARPFHRLTITQAIQKYAPGYGDAQLADPAFLRTELKRFGVD
HHHHHCCEEEEECCCEECHHCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
VGQPAFLNAGLGALQLALFEETAESQLWEPTYIIDYPVEVSPLARASDTVPGITERFELF
CCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCCHHHHHHHH
MTGREIANGFSELNDPEDQAARFKKQVEQKDAGDEEAMFFDADYIRALEYGMPPTGGCGI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHCCCCCCCCCCC
GIDRLVMLLTDSPTIRDVLLFPHLRRED
CHHHHHHHHCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA