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The map label for this gene is kdgR [H]

Identifier: 238027931

GI number: 238027931

Start: 2608686

End: 2609519

Strand: Direct

Name: kdgR [H]

Synonym: bglu_1g23760

Alternate gene names: 238027931

Gene position: 2608686-2609519 (Clockwise)

Preceding gene: 238027927

Following gene: 238027933

Centisome position: 66.78

GC content: 68.59

Gene sequence:

>834_bases
ATGGAAGCGATGCTCAGGCGGCGCCGGGAACACGCGCCGCAGCCGCCGGCCGAAGGCGGCGCCGATAAGGCGGAATCGGC
CTCGGCCACGGGCAAGGTGTTCGCCGTGCTCGAGGCGCTCGGCACGCACGGGCCGAGCGGCATCAGCGAGCTGTCGCACC
GGCTCGGCATATCGAAGACCACCGTCCACCGGTTCCTGCAGACGCTGAAGACGCTCGGCTTCGTCGCGCAGGAAGACGAG
ACCGAACGCTACCGTCTGACGATCCGGCTGTTCGAACTCGGCTCGCTGGCGCTCGAGAGCGTGGACCTGATCCGCGAGGC
CGACCTCGAGATGCGCCGCATCGGCCGGCTCACGCGCGAGGCGCTGCACCTCGGCGCGTTCGACGCAGACCACATCATCT
ACATCCACAAGATCGACGCCGATTACGGGCTGCGCATGCACTCGCGGATCGGCCGCACCAACCCGCTCTACAGCACCGCG
ATCGGCAAGGTGCTGCTGGCCTGGATGGCGCCCGAGGAGGCGCGCGAGACGCTCTCGCGGATCGAGTTCAGGAAGTCGAC
GCAGAAGACGCTGGCCTCGGCCGAGGCCGTCTGGAGCATTCTTCCGCATGTGCGCGAGCAGGGCTATGGCGAGGACAACG
AGGAGCAGGAAGACGGGCTCTTATGCCTCGCGGTGCCGGTGTTCGACCGCTTCGGCCGCGTGATCGCGGGGCTGTCGATC
TCGTTTCCGACCATGCGCTGCGGCGCCGACACGAAGGCGCACTACGTCGCGCTGCTCAAGCAGGCCGGGCAGGCCATCTC
GGCCAGGCTCGGCTATCACGGCGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
CCACGCTCGCGGCGGACGGCGGCCGGCTCGCCCGCTGATTCAACCCCAGCCGGGACGCGCTATGCTCAAGCCTGACTCCA
CACCGACGGACGTTTCGCAC

Downstream 100 bases:

>100_bases
AGGCGGCGGGCGGGCGCTGAATCGCCTCGACGGGGCATGCCGGCGTGCTCCGCATCGGCCGCGGGCGCGCCTCGGCCGCC
GCTCGCGTCTTATGTCGCTG

Product: DNA-binding transcriptional regulator KdgR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MEAMLRRRREHAPQPPAEGGADKAESASATGKVFAVLEALGTHGPSGISELSHRLGISKTTVHRFLQTLKTLGFVAQEDE
TERYRLTIRLFELGSLALESVDLIREADLEMRRIGRLTREALHLGAFDADHIIYIHKIDADYGLRMHSRIGRTNPLYSTA
IGKVLLAWMAPEEARETLSRIEFRKSTQKTLASAEAVWSILPHVREQGYGEDNEEQEDGLLCLAVPVFDRFGRVIAGLSI
SFPTMRCGADTKAHYVALLKQAGQAISARLGYHGARA

Sequences:

>Translated_277_residues
MEAMLRRRREHAPQPPAEGGADKAESASATGKVFAVLEALGTHGPSGISELSHRLGISKTTVHRFLQTLKTLGFVAQEDE
TERYRLTIRLFELGSLALESVDLIREADLEMRRIGRLTREALHLGAFDADHIIYIHKIDADYGLRMHSRIGRTNPLYSTA
IGKVLLAWMAPEEARETLSRIEFRKSTQKTLASAEAVWSILPHVREQGYGEDNEEQEDGLLCLAVPVFDRFGRVIAGLSI
SFPTMRCGADTKAHYVALLKQAGQAISARLGYHGARA
>Mature_277_residues
MEAMLRRRREHAPQPPAEGGADKAESASATGKVFAVLEALGTHGPSGISELSHRLGISKTTVHRFLQTLKTLGFVAQEDE
TERYRLTIRLFELGSLALESVDLIREADLEMRRIGRLTREALHLGAFDADHIIYIHKIDADYGLRMHSRIGRTNPLYSTA
IGKVLLAWMAPEEARETLSRIEFRKSTQKTLASAEAVWSILPHVREQGYGEDNEEQEDGLLCLAVPVFDRFGRVIAGLSI
SFPTMRCGADTKAHYVALLKQAGQAISARLGYHGARA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=258, Percent_Identity=60.4651162790698, Blast_Score=327, Evalue=5e-91,
Organism=Escherichia coli, GI1786468, Length=225, Percent_Identity=40.8888888888889, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789999, Length=242, Percent_Identity=34.297520661157, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082359, Length=274, Percent_Identity=29.1970802919708, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786715, Length=271, Percent_Identity=28.4132841328413, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790752, Length=238, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788581, Length=250, Percent_Identity=25.2, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30686; Mature: 30686

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAMLRRRREHAPQPPAEGGADKAESASATGKVFAVLEALGTHGPSGISELSHRLGISKT
CHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHH
TVHRFLQTLKTLGFVAQEDETERYRLTIRLFELGSLALESVDLIREADLEMRRIGRLTRE
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALHLGAFDADHIIYIHKIDADYGLRMHSRIGRTNPLYSTAIGKVLLAWMAPEEARETLSR
HHHHCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
IEFRKSTQKTLASAEAVWSILPHVREQGYGEDNEEQEDGLLCLAVPVFDRFGRVIAGLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCC
SFPTMRCGADTKAHYVALLKQAGQAISARLGYHGARA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEAMLRRRREHAPQPPAEGGADKAESASATGKVFAVLEALGTHGPSGISELSHRLGISKT
CHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHH
TVHRFLQTLKTLGFVAQEDETERYRLTIRLFELGSLALESVDLIREADLEMRRIGRLTRE
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALHLGAFDADHIIYIHKIDADYGLRMHSRIGRTNPLYSTAIGKVLLAWMAPEEARETLSR
HHHHCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
IEFRKSTQKTLASAEAVWSILPHVREQGYGEDNEEQEDGLLCLAVPVFDRFGRVIAGLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCC
SFPTMRCGADTKAHYVALLKQAGQAISARLGYHGARA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]