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The map label for this gene is fabF [H]

Identifier: 238027864

GI number: 238027864

Start: 2509340

End: 2510566

Strand: Reverse

Name: fabF [H]

Synonym: bglu_1g22950

Alternate gene names: 238027864

Gene position: 2510566-2509340 (Counterclockwise)

Preceding gene: 238027865

Following gene: 238027863

Centisome position: 64.27

GC content: 70.99

Gene sequence:

>1227_bases
ATGCGCGCGGCGCGGACCGTGGTGGTCACGGGCATGGGAGCGGTGTCGCCGCTCGGCGCGACCCCGGCTTCCATGTTCGC
AGCGCTTTGCGACGGGCGCAGCGGCATCACGCGGCATCCCGATCCGGGCATCACGCGCTGCGTCGGCGTGGCCGACGTCG
ATCCCACCGCTCACTTCTCGCGGCGCATGCTCGATTGCTGCGACCGCGCCACCTTGCTCGCGATGATCGCCGCGCAGCAG
GCCGGCAACGCGGCCGGGCTGCAAGACGCGGCGCTGCGCGAGCGCTGTGGCGTGTTCATCGGTACCGGTATTGGCGGCGT
CGGCTCGCTCGTGGAGGGCGTGCTGTCGTTTCACGGCCTGATGCGCAAGGGGCCGAAGCTCATCATTCCGGCGGCGATGC
CGAACGCGATCGCCGCGCATATCGCGATGCAGATCAAGACGCGCGCCGAGGCGCAGACCTACGCGACCGCCTGCACGGCC
GGCGCGGTCGCGCTCGGCGAGGCGTTCCGGCGCGTGCGTGACGGGTATCTCGACATCGCGCTGTGCGGCGCGAGCGAATC
GATGCTGACGCCCGAACTGATCGGCGCCTGGCAACAGGCGCGCGTGCTCTGCGACGAGCCCCCCGAGGCGCCGCACACCG
GCTGCCGGCCGTTCAGCGCGGCGCGTACCGGCATCACGGTCGGCGAGGGCGCCGCGATCTTCTGTATCGAGCATCTCGAT
CACGCGCTGGCGCGCGGCGCAGTGCCGCTCGCCGAACTGGCCGGCTACGGCACCAGCAACGACAGCACGCATCTCGCGAA
GCCCGATCCCTCGGGCCAGGCGCTCGCCATCGAGCGCGCGCTCGCGGACGCCGGCATCGGGCCGGACGCGATCGGCTACG
TGAACGCGCACGCCACCGGCACGCACGGCGGCGACGCGGCCGAAACGCAGGCGCTGAAGCTCGCGCTCGGCAGCCATGCG
GCGCGCATTCCCGTCAGCAGCACGAAGGGCGCCACCGGCCATCTGATCGGCGCGGCCGGCGCGCTCGAATTCGCGATCTG
CGTGAAGGCGCTGCAACAGCAGCGCGTGCCGCCGACGCTGTACTTCGACGCACTCGATCCGCTCTGCGACCTCGACCATG
TGCCCGATCGCGCACGCCGCGTCGATGGGCTCGACTACGTGCTGAGCAATTCGTTCGGCATGGGCGGCAATAACGCGAGT
CTGGTCGCGCGAAGATTCATTCCGTAG

Upstream 100 bases:

>100_bases
CCGGTGGCATCGTGCCCTTGCCGCTCGATCTCGAGGAACTGGCCGGGCAGGTCGAGGCGACGGTCTGCCGCCTGAAATAC
GCACAGGCGGGGTCGCTCTG

Downstream 100 bases:

>100_bases
TCCTTTTATTCTTGTCGTTCGTCAATAATCAGGATCGTTCCCGAGACGTCGACTGCCTGCAGCGTTAGAGTTGAGAGTCG
GCACGGCGCCTCGGCCGTTC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRAARTVVVTGMGAVSPLGATPASMFAALCDGRSGITRHPDPGITRCVGVADVDPTAHFSRRMLDCCDRATLLAMIAAQQ
AGNAAGLQDAALRERCGVFIGTGIGGVGSLVEGVLSFHGLMRKGPKLIIPAAMPNAIAAHIAMQIKTRAEAQTYATACTA
GAVALGEAFRRVRDGYLDIALCGASESMLTPELIGAWQQARVLCDEPPEAPHTGCRPFSAARTGITVGEGAAIFCIEHLD
HALARGAVPLAELAGYGTSNDSTHLAKPDPSGQALAIERALADAGIGPDAIGYVNAHATGTHGGDAAETQALKLALGSHA
ARIPVSSTKGATGHLIGAAGALEFAICVKALQQQRVPPTLYFDALDPLCDLDHVPDRARRVDGLDYVLSNSFGMGGNNAS
LVARRFIP

Sequences:

>Translated_408_residues
MRAARTVVVTGMGAVSPLGATPASMFAALCDGRSGITRHPDPGITRCVGVADVDPTAHFSRRMLDCCDRATLLAMIAAQQ
AGNAAGLQDAALRERCGVFIGTGIGGVGSLVEGVLSFHGLMRKGPKLIIPAAMPNAIAAHIAMQIKTRAEAQTYATACTA
GAVALGEAFRRVRDGYLDIALCGASESMLTPELIGAWQQARVLCDEPPEAPHTGCRPFSAARTGITVGEGAAIFCIEHLD
HALARGAVPLAELAGYGTSNDSTHLAKPDPSGQALAIERALADAGIGPDAIGYVNAHATGTHGGDAAETQALKLALGSHA
ARIPVSSTKGATGHLIGAAGALEFAICVKALQQQRVPPTLYFDALDPLCDLDHVPDRARRVDGLDYVLSNSFGMGGNNAS
LVARRFIP
>Mature_408_residues
MRAARTVVVTGMGAVSPLGATPASMFAALCDGRSGITRHPDPGITRCVGVADVDPTAHFSRRMLDCCDRATLLAMIAAQQ
AGNAAGLQDAALRERCGVFIGTGIGGVGSLVEGVLSFHGLMRKGPKLIIPAAMPNAIAAHIAMQIKTRAEAQTYATACTA
GAVALGEAFRRVRDGYLDIALCGASESMLTPELIGAWQQARVLCDEPPEAPHTGCRPFSAARTGITVGEGAAIFCIEHLD
HALARGAVPLAELAGYGTSNDSTHLAKPDPSGQALAIERALADAGIGPDAIGYVNAHATGTHGGDAAETQALKLALGSHA
ARIPVSSTKGATGHLIGAAGALEFAICVKALQQQRVPPTLYFDALDPLCDLDHVPDRARRVDGLDYVLSNSFGMGGNNAS
LVARRFIP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=419, Percent_Identity=36.0381861575179, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=48.2758620689655, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI41872631, Length=332, Percent_Identity=25.6024096385542, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787337, Length=416, Percent_Identity=38.9423076923077, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1788663, Length=413, Percent_Identity=30.9927360774818, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=34.2168674698795, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI71983535, Length=267, Percent_Identity=37.0786516853933, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17550940, Length=315, Percent_Identity=26.6666666666667, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI212642053, Length=353, Percent_Identity=24.0793201133144, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=444, Percent_Identity=30.6306306306306, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24644341, Length=421, Percent_Identity=36.104513064133, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24581345, Length=358, Percent_Identity=27.0949720670391, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330659, Length=277, Percent_Identity=24.5487364620939, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920632, Length=277, Percent_Identity=24.5487364620939, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41995; Mature: 41995

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAARTVVVTGMGAVSPLGATPASMFAALCDGRSGITRHPDPGITRCVGVADVDPTAHFS
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHEEECCCCCCHHHHH
RRMLDCCDRATLLAMIAAQQAGNAAGLQDAALRERCGVFIGTGIGGVGSLVEGVLSFHGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHH
MRKGPKLIIPAAMPNAIAAHIAMQIKTRAEAQTYATACTAGAVALGEAFRRVRDGYLDIA
HHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LCGASESMLTPELIGAWQQARVLCDEPPEAPHTGCRPFSAARTGITVGEGAAIFCIEHLD
EECCCCCCCCHHHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCEECCCCCEEHHHHHH
HALARGAVPLAELAGYGTSNDSTHLAKPDPSGQALAIERALADAGIGPDAIGYVNAHATG
HHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEEEEECCCCC
THGGDAAETQALKLALGSHAARIPVSSTKGATGHLIGAAGALEFAICVKALQQQRVPPTL
CCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCEE
YFDALDPLCDLDHVPDRARRVDGLDYVLSNSFGMGGNNASLVARRFIP
EHHCCCCHHCCCCCCHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MRAARTVVVTGMGAVSPLGATPASMFAALCDGRSGITRHPDPGITRCVGVADVDPTAHFS
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHEEECCCCCCHHHHH
RRMLDCCDRATLLAMIAAQQAGNAAGLQDAALRERCGVFIGTGIGGVGSLVEGVLSFHGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHH
MRKGPKLIIPAAMPNAIAAHIAMQIKTRAEAQTYATACTAGAVALGEAFRRVRDGYLDIA
HHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LCGASESMLTPELIGAWQQARVLCDEPPEAPHTGCRPFSAARTGITVGEGAAIFCIEHLD
EECCCCCCCCHHHHCCHHHHHHCCCCCCCCCCCCCCCCHHHHCCCEECCCCCEEHHHHHH
HALARGAVPLAELAGYGTSNDSTHLAKPDPSGQALAIERALADAGIGPDAIGYVNAHATG
HHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEEEEECCCCC
THGGDAAETQALKLALGSHAARIPVSSTKGATGHLIGAAGALEFAICVKALQQQRVPPTL
CCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCEE
YFDALDPLCDLDHVPDRARRVDGLDYVLSNSFGMGGNNASLVARRFIP
EHHCCCCHHCCCCCCHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]