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The map label for this gene is tcp [H]

Identifier: 238027762

GI number: 238027762

Start: 2375361

End: 2377040

Strand: Reverse

Name: tcp [H]

Synonym: bglu_1g21860

Alternate gene names: 238027762

Gene position: 2377040-2375361 (Counterclockwise)

Preceding gene: 238027764

Following gene: 238027757

Centisome position: 60.85

GC content: 71.19

Gene sequence:

>1680_bases
ATGATGGGGATTTCGCTGCGCGCTCGACCGGTAACGGACCGCGGCCCGGCAGGCGCTGCCACGCCGGCCGCGCGGACCCG
CCCACCACGCGCGCCGCGGCACGCCGGCACCGGGCCCGCGCGCGCGTGGTCGGTGCGCGCGACGCTGTTCGCCGCGTTCG
CGGTGGTGCTGATCGGCACGCTCGCCATCGGATTGTTCTCGCTCTGGCAGATCAGCAAGCTCGACGACTCGATCGGCTCG
GTCTATGCGCAGGGGCACGTGGCGAGCAACGCGGCCGAGACGGTGCGGGCCCACGTGCTGCGCGCGAGCCGTGCGCAGAA
GATGCTGCTGACCGCGACCACCGCGAAGGAGCGCGACGATCTCGGCAACGACATCGAGCAGGCGCTCGTCGGCATCATCA
GCGAAATCAAGGTGCTGCAGCGCTACACGGCCCCGGGCGAACGCGCCGCGCTCGATCCGTTCAGCAAGGCGGTGGCGGGC
TGGAGTGGGCACTTGCGCGATTTCGTGACGCTCGTCAAGCAGCAGCCGCTGGATCTGTCGCAGATGAACTGGCAGGTCGG
CACCCAGGACGTCTCGCTGCTGGTCGAGACCGGCAAGCTCGAGAAGCAGGTGGACGCGCTGGTCGCCGCCTGCGGCGAGG
CCGCCAAGGCCACCCGCGACGCCTCCACCGCACGCTTTCATGCCTCGTTCCTGATGATCGCGGCGATGACGGCCGCGCTG
ATCGTGGTCGCGATCCTGATCGCCGGCTGGGTGGTGCGTCGGCTTGGGGTGCAGCTCGGCGGCGAGCCCGCCACCGCGAA
GACCATCGCGGCCGGCATCGCGAGGGGCGACCTGTCGCACCACGTCACGCTGTCCAAGCACGATCGCGGCAGCGTGCTGT
ACGCGCTCGACGACATGCAGCGCCAGCTGGCCAGCACGGTGCGCGAGATCGCGGCCAGCGCCGAGGCAATCGCCTCGGCC
TCGGGCGAGATCTCGACCGGCAACCTCGACCTGTCGCAGCGCACCGAGCAGCAGGCGGTCGCGCTCGAACGAACCTCGTC
GAGCATGTCGCAGCTCACTTCCACGGTGCACCAGAACGCCGAGAACGCGCGGCAGGCCAGCGCGCTCGCGCAGAACGCGT
CGGACGTGGCCGAGCAGGGCGGCTCGGTGGTCAGCCGCGTGGTGGCGACCATGAACGAGATCGACGCGAGCGCGAAGAGC
ATCCGCGACATCATCGGCACCATCGAGGGCATCGCGTTCCAGACCAACATCCTCGCGCTGAACGCGGCGGTGGAGGCCGC
GCGCGCCGGCGAGAACGGCCGCGGCTTCTCGGTGGTGGCGAGCGAAGTGCGCTCGCTCGCGCAGCGCTCGGCGACGGCCG
CCAAGGAGATCCGCCAGTTGATCGGCACCTCGGTCGAGCGCGTCGCCAACGGCGCACAGCTGGCGACCGACGCCGGCCAG
ACGATGGAGGAGGTGGTGCGCGCGGTGCGGCGCGTGACCGACATCATCGGCGAGATCTCGGCGGCCTCGACCGAGCAGAG
CGCCGGGATCGACGAGATCGGCCGCGCGGTCGAGCAGATGGACGCCGGCACCCAGCAGAACGCGGCGCTCGTCGAACAGG
CGGCCGCCGCGGCGCGCTCGCTCGACGAGCAGGCGCAGGCGCTGAAGGCACTGGTCGGACACTTCCGGCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
CGACACGCACGAAAAGGGCCATGCCGCAGACCCGCGGCTCGGCCGAACGGTGAAGCCGGAGCCGATCGATCCGGCGCAGC
AACAGGACGGGGAGAATTCG

Downstream 100 bases:

>100_bases
GTTCAGGCGAAGGCCGCCCACCGCACCGCGGGCCGCATGGCGGCCGGCGCCGGCCGGGCCGGTCGCCGTTTCAGGGCCTG
GCCGGCGCGGTGGCCGCAGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MMGISLRARPVTDRGPAGAATPAARTRPPRAPRHAGTGPARAWSVRATLFAAFAVVLIGTLAIGLFSLWQISKLDDSIGS
VYAQGHVASNAAETVRAHVLRASRAQKMLLTATTAKERDDLGNDIEQALVGIISEIKVLQRYTAPGERAALDPFSKAVAG
WSGHLRDFVTLVKQQPLDLSQMNWQVGTQDVSLLVETGKLEKQVDALVAACGEAAKATRDASTARFHASFLMIAAMTAAL
IVVAILIAGWVVRRLGVQLGGEPATAKTIAAGIARGDLSHHVTLSKHDRGSVLYALDDMQRQLASTVREIAASAEAIASA
SGEISTGNLDLSQRTEQQAVALERTSSSMSQLTSTVHQNAENARQASALAQNASDVAEQGGSVVSRVVATMNEIDASAKS
IRDIIGTIEGIAFQTNILALNAAVEAARAGENGRGFSVVASEVRSLAQRSATAAKEIRQLIGTSVERVANGAQLATDAGQ
TMEEVVRAVRRVTDIIGEISAASTEQSAGIDEIGRAVEQMDAGTQQNAALVEQAAAAARSLDEQAQALKALVGHFRLAA

Sequences:

>Translated_559_residues
MMGISLRARPVTDRGPAGAATPAARTRPPRAPRHAGTGPARAWSVRATLFAAFAVVLIGTLAIGLFSLWQISKLDDSIGS
VYAQGHVASNAAETVRAHVLRASRAQKMLLTATTAKERDDLGNDIEQALVGIISEIKVLQRYTAPGERAALDPFSKAVAG
WSGHLRDFVTLVKQQPLDLSQMNWQVGTQDVSLLVETGKLEKQVDALVAACGEAAKATRDASTARFHASFLMIAAMTAAL
IVVAILIAGWVVRRLGVQLGGEPATAKTIAAGIARGDLSHHVTLSKHDRGSVLYALDDMQRQLASTVREIAASAEAIASA
SGEISTGNLDLSQRTEQQAVALERTSSSMSQLTSTVHQNAENARQASALAQNASDVAEQGGSVVSRVVATMNEIDASAKS
IRDIIGTIEGIAFQTNILALNAAVEAARAGENGRGFSVVASEVRSLAQRSATAAKEIRQLIGTSVERVANGAQLATDAGQ
TMEEVVRAVRRVTDIIGEISAASTEQSAGIDEIGRAVEQMDAGTQQNAALVEQAAAAARSLDEQAQALKALVGHFRLAA
>Mature_559_residues
MMGISLRARPVTDRGPAGAATPAARTRPPRAPRHAGTGPARAWSVRATLFAAFAVVLIGTLAIGLFSLWQISKLDDSIGS
VYAQGHVASNAAETVRAHVLRASRAQKMLLTATTAKERDDLGNDIEQALVGIISEIKVLQRYTAPGERAALDPFSKAVAG
WSGHLRDFVTLVKQQPLDLSQMNWQVGTQDVSLLVETGKLEKQVDALVAACGEAAKATRDASTARFHASFLMIAAMTAAL
IVVAILIAGWVVRRLGVQLGGEPATAKTIAAGIARGDLSHHVTLSKHDRGSVLYALDDMQRQLASTVREIAASAEAIASA
SGEISTGNLDLSQRTEQQAVALERTSSSMSQLTSTVHQNAENARQASALAQNASDVAEQGGSVVSRVVATMNEIDASAKS
IRDIIGTIEGIAFQTNILALNAAVEAARAGENGRGFSVVASEVRSLAQRSATAAKEIRQLIGTSVERVANGAQLATDAGQ
TMEEVVRAVRRVTDIIGEISAASTEQSAGIDEIGRAVEQMDAGTQQNAALVEQAAAAARSLDEQAQALKALVGHFRLAA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=288, Percent_Identity=59.0277777777778, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI2367378, Length=314, Percent_Identity=51.5923566878981, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1788194, Length=405, Percent_Identity=45.679012345679, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1787690, Length=331, Percent_Identity=51.3595166163142, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1789453, Length=334, Percent_Identity=36.8263473053892, Blast_Score=182, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58517; Mature: 58517

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGISLRARPVTDRGPAGAATPAARTRPPRAPRHAGTGPARAWSVRATLFAAFAVVLIGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAIGLFSLWQISKLDDSIGSVYAQGHVASNAAETVRAHVLRASRAQKMLLTATTAKERDD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGNDIEQALVGIISEIKVLQRYTAPGERAALDPFSKAVAGWSGHLRDFVTLVKQQPLDLS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCHH
QMNWQVGTQDVSLLVETGKLEKQVDALVAACGEAAKATRDASTARFHASFLMIAAMTAAL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
IVVAILIAGWVVRRLGVQLGGEPATAKTIAAGIARGDLSHHVTLSKHDRGSVLYALDDMQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEEEHHHHHH
RQLASTVREIAASAEAIASASGEISTGNLDLSQRTEQQAVALERTSSSMSQLTSTVHQNA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENARQASALAQNASDVAEQGGSVVSRVVATMNEIDASAKSIRDIIGTIEGIAFQTNILAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAAVEAARAGENGRGFSVVASEVRSLAQRSATAAKEIRQLIGTSVERVANGAQLATDAGQ
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TMEEVVRAVRRVTDIIGEISAASTEQSAGIDEIGRAVEQMDAGTQQNAALVEQAAAAARS
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LDEQAQALKALVGHFRLAA
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMGISLRARPVTDRGPAGAATPAARTRPPRAPRHAGTGPARAWSVRATLFAAFAVVLIGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LAIGLFSLWQISKLDDSIGSVYAQGHVASNAAETVRAHVLRASRAQKMLLTATTAKERDD
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGNDIEQALVGIISEIKVLQRYTAPGERAALDPFSKAVAGWSGHLRDFVTLVKQQPLDLS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCHH
QMNWQVGTQDVSLLVETGKLEKQVDALVAACGEAAKATRDASTARFHASFLMIAAMTAAL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
IVVAILIAGWVVRRLGVQLGGEPATAKTIAAGIARGDLSHHVTLSKHDRGSVLYALDDMQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCEEEHHHHHH
RQLASTVREIAASAEAIASASGEISTGNLDLSQRTEQQAVALERTSSSMSQLTSTVHQNA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENARQASALAQNASDVAEQGGSVVSRVVATMNEIDASAKSIRDIIGTIEGIAFQTNILAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAAVEAARAGENGRGFSVVASEVRSLAQRSATAAKEIRQLIGTSVERVANGAQLATDAGQ
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TMEEVVRAVRRVTDIIGEISAASTEQSAGIDEIGRAVEQMDAGTQQNAALVEQAAAAARS
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LDEQAQALKALVGHFRLAA
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]