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The map label for this gene is nocM [H]

Identifier: 238027408

GI number: 238027408

Start: 1983108

End: 1983854

Strand: Reverse

Name: nocM [H]

Synonym: bglu_1g18040

Alternate gene names: 238027408

Gene position: 1983854-1983108 (Counterclockwise)

Preceding gene: 238027409

Following gene: 238027407

Centisome position: 50.78

GC content: 70.41

Gene sequence:

>747_bases
ATGCCTATCGATTTTCCGTTCCTGCTCGACACCATGCGGCAGCTGATCGCCGCCGTGCCGACCACGCTGGGGCTGTTCTT
CCTGTCGCTGGTGCTGGGCGGGCTGCTCTCGCTCGTGATCGTCACGCTGCGCGTGTCGCCGCACTGGCTGCCGAACCGCT
TCGCGCGCGCCTACATCCTGGTGTTCCGCGGCTCGCCGCTCCTGATCCAGATGTTCCTCGTCTACTACGGGCTCGGCCAG
TTCGGCGTGATCCGCGAGAGCTTCCTGTGGCCGGTGCTGCGCGAGCCCTACGTGTGCGCGGTGCTCTCGCTCGCGCTCTG
TACCGCCGGCTACACGGCCGAGATCATCCGCGGCGGCCTGATGGCGGTGCCGGTCGGGCAGATCGAGGCCGGCCAGGCGA
TCGGCCTGTCGGGCTTCGCGCTGCTGCGCCGCGTGATCGGCCCGATCGCGCTGCGCCAGTGCCTGCCGGCTTACTCGACC
GAAGCGGTGCTGCTCGTCAAATCCACCGCGCTCGCGAGCCTGGTGACGGTGTGGGAGGTCACGGGCGTCGCGCAGCAGAT
CATCCAGCAGACCTACCGCACCACCGAGGTGTTCGCCTGCGCGGCGCTGATCTACCTGTTCCTGAACTTCTTCGTGGTGC
GCGTGCTCGGCTGCGTCGAGGCGCGGCTCTCACGCCACCTGCGCGCCGCGCCGGCGCTGGCGGCGCCCACCGCCGCCACG
CTCGAGGCGCGCCGCGCCGCGCCCTGA

Upstream 100 bases:

>100_bases
GACGAGCCTCTCGAACCGCGTCTTCGGCACGGCCGAGGCGCGCGTGGGCCGCTCGTTCAAGCGCAGCTTCGCACGCAACT
GACGTCACGGCGGCCACCTC

Downstream 100 bases:

>100_bases
GCGATCGCCCCATTCCCAGTTGGAGACACGCATGCCTGCCGTCAATCCCGTCGCGCTGTCCGCGCGCAACATCCACAAGT
CGTTCGGTGATCACCACGTG

Product: Polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MPIDFPFLLDTMRQLIAAVPTTLGLFFLSLVLGGLLSLVIVTLRVSPHWLPNRFARAYILVFRGSPLLIQMFLVYYGLGQ
FGVIRESFLWPVLREPYVCAVLSLALCTAGYTAEIIRGGLMAVPVGQIEAGQAIGLSGFALLRRVIGPIALRQCLPAYST
EAVLLVKSTALASLVTVWEVTGVAQQIIQQTYRTTEVFACAALIYLFLNFFVVRVLGCVEARLSRHLRAAPALAAPTAAT
LEARRAAP

Sequences:

>Translated_248_residues
MPIDFPFLLDTMRQLIAAVPTTLGLFFLSLVLGGLLSLVIVTLRVSPHWLPNRFARAYILVFRGSPLLIQMFLVYYGLGQ
FGVIRESFLWPVLREPYVCAVLSLALCTAGYTAEIIRGGLMAVPVGQIEAGQAIGLSGFALLRRVIGPIALRQCLPAYST
EAVLLVKSTALASLVTVWEVTGVAQQIIQQTYRTTEVFACAALIYLFLNFFVVRVLGCVEARLSRHLRAAPALAAPTAAT
LEARRAAP
>Mature_247_residues
PIDFPFLLDTMRQLIAAVPTTLGLFFLSLVLGGLLSLVIVTLRVSPHWLPNRFARAYILVFRGSPLLIQMFLVYYGLGQF
GVIRESFLWPVLREPYVCAVLSLALCTAGYTAEIIRGGLMAVPVGQIEAGQAIGLSGFALLRRVIGPIALRQCLPAYSTE
AVLLVKSTALASLVTVWEVTGVAQQIIQQTYRTTEVFACAALIYLFLNFFVVRVLGCVEARLSRHLRAAPALAAPTAATL
EARRAAP

Specific function: Component of the nopaline active transport system probably consisting of four subunits:Q, M, P and T. This system is also capable of transporting octopine provided that catabolic functions are induced with nopaline [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788645, Length=229, Percent_Identity=36.6812227074236, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=36.6515837104072, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1788226, Length=221, Percent_Identity=33.9366515837104, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787030, Length=229, Percent_Identity=30.1310043668122, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787087, Length=230, Percent_Identity=30.8695652173913, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788646, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786874, Length=183, Percent_Identity=28.4153005464481, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994930, Length=124, Percent_Identity=31.4516129032258, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786873, Length=205, Percent_Identity=25.8536585365854, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082239, Length=170, Percent_Identity=28.2352941176471, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26993; Mature: 26861

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCC
>Mature Secondary Structure 
PIDFPFLLDTMRQLIAAVPTTLGLFFLSLVLGGLLSLVIVTLRVSPHWLPNRFARAYIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VFRGSPLLIQMFLVYYGLGQFGVIRESFLWPVLREPYVCAVLSLALCTAGYTAEIIRGGL
EECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHCCC
MAVPVGQIEAGQAIGLSGFALLRRVIGPIALRQCLPAYSTEAVLLVKSTALASLVTVWEV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHH
TGVAQQIIQQTYRTTEVFACAALIYLFLNFFVVRVLGCVEARLSRHLRAAPALAAPTAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LEARRAAP
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1732218; 11743193; 11743194 [H]