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The map label for this gene is degA [H]

Identifier: 238027371

GI number: 238027371

Start: 1938094

End: 1939140

Strand: Reverse

Name: degA [H]

Synonym: bglu_1g17660

Alternate gene names: 238027371

Gene position: 1939140-1938094 (Counterclockwise)

Preceding gene: 238027377

Following gene: 238027370

Centisome position: 49.64

GC content: 75.17

Gene sequence:

>1047_bases
ATGCCGACCCTCGCCGAAGTCGCCCAAGCCGCGGGCGTGACGCCCGCCACCGTCTCGAACGTGCTGCGCAACCGCGGCCG
GGTCGGGGCGCTCACGCGCGAACGCGTGCTGGCCGCCGTCGAGGCGCTCGGCTACCGGCCGCACCTGGCCGCGCGCGCGC
TCGCGGAAGGGCGCGCGCCGACCATCGCGCTGATGGTATCGAGCATCGCCAACCCGTTCTATCCGGAATTCGCACTAGCG
GTGGAGAGCGCGCTGCGCGGCAGCGGCCGCTACCTGATCATCTGCAACACCGAGAACGATCCGGGCATCGGCCGCGGCTA
CCTGGAGCAGATCGCCGGCACGCTGTCGGAGGGCGTGCTGGTGATGAACGCGAACCTGGATCTGGACGACCTGCATGCCA
CCGTGGCACGCGGCACGCCGGTGGTGCTCTGCATGTGGGAGCGGCCCGAGCTGCCGCCGGGGCTGCCTTGCGTGGCGGTG
GATTTCCGTCTGGCGGGCGAACTGGCGGCCAGACATCTGCTCGCGCTCGGCCATCGGCGGATCGGCGCGCTGGTCGGCAG
CAAGGTGTCGGGCATCCATGCGGCACGCTGCGAGGGCTTCGTCGCCGCGCTCGACGCGGCCGGCCTGGACGGCGCGCGCG
CGCCGGTGCGCTACGCGCCGGACACGATCGAGGGCGGCTACGCGGCCGCGCGCGCGCTGCTCGCCGAGTCGCCGCAGCTC
ACGGCGCTGTTCGCCACCAACGACCTGCCCGCGCTCGGCGCGATGCACGCGGCGGCCGACGCCGGCCGCCGCGTGCCGGA
CGATCTGTCGGTGATCGGCATCACCGACATTCAACTGGCCGCGCAGTCGCGGCCCGCGCTGACCACCGTCGCCGTGCCGA
CCGCCGAGGCGGCCGCGCTGGCCGTCGCGCTGCTCGCGGAACTGGCCGGGCCGGGCGGCGCGAGCGGTGAAGGCGGCGCG
CACGCGGCGCCGCGCATGCGCGTGACCGGTGAGCCGCGGCTCGTGGTGCGCGCCTCGACGGCACCGCCGCGCGGCGCCGT
CGCCTGA

Upstream 100 bases:

>100_bases
GTGTCAGGCCGTCTCCGTTTTTTCCTTCTGATATCGGCTCATCATGCAACGAGCCGGCGCCGCTGACAAATATTGAGACT
AGATTTCATTTACTGAGACA

Downstream 100 bases:

>100_bases
TCGCGCGGCGGGAGATGCCGGCCGCCGCGCGAGGCACGCACGACATTCGGTCCGGCTGCGCCGGCCGATGAATCGATTAG
AATCTGATTAACATATCAAC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPTLAEVAQAAGVTPATVSNVLRNRGRVGALTRERVLAAVEALGYRPHLAARALAEGRAPTIALMVSSIANPFYPEFALA
VESALRGSGRYLIICNTENDPGIGRGYLEQIAGTLSEGVLVMNANLDLDDLHATVARGTPVVLCMWERPELPPGLPCVAV
DFRLAGELAARHLLALGHRRIGALVGSKVSGIHAARCEGFVAALDAAGLDGARAPVRYAPDTIEGGYAAARALLAESPQL
TALFATNDLPALGAMHAAADAGRRVPDDLSVIGITDIQLAAQSRPALTTVAVPTAEAAALAVALLAELAGPGGASGEGGA
HAAPRMRVTGEPRLVVRASTAPPRGAVA

Sequences:

>Translated_348_residues
MPTLAEVAQAAGVTPATVSNVLRNRGRVGALTRERVLAAVEALGYRPHLAARALAEGRAPTIALMVSSIANPFYPEFALA
VESALRGSGRYLIICNTENDPGIGRGYLEQIAGTLSEGVLVMNANLDLDDLHATVARGTPVVLCMWERPELPPGLPCVAV
DFRLAGELAARHLLALGHRRIGALVGSKVSGIHAARCEGFVAALDAAGLDGARAPVRYAPDTIEGGYAAARALLAESPQL
TALFATNDLPALGAMHAAADAGRRVPDDLSVIGITDIQLAAQSRPALTTVAVPTAEAAALAVALLAELAGPGGASGEGGA
HAAPRMRVTGEPRLVVRASTAPPRGAVA
>Mature_347_residues
PTLAEVAQAAGVTPATVSNVLRNRGRVGALTRERVLAAVEALGYRPHLAARALAEGRAPTIALMVSSIANPFYPEFALAV
ESALRGSGRYLIICNTENDPGIGRGYLEQIAGTLSEGVLVMNANLDLDDLHATVARGTPVVLCMWERPELPPGLPCVAVD
FRLAGELAARHLLALGHRRIGALVGSKVSGIHAARCEGFVAALDAAGLDGARAPVRYAPDTIEGGYAAARALLAESPQLT
ALFATNDLPALGAMHAAADAGRRVPDDLSVIGITDIQLAAQSRPALTTVAVPTAEAAALAVALLAELAGPGGASGEGGAH
AAPRMRVTGEPRLVVRASTAPPRGAVA

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788474, Length=350, Percent_Identity=34.5714285714286, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=32.6666666666667, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=31.9488817891374, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=30.1775147928994, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787948, Length=308, Percent_Identity=31.4935064935065, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789068, Length=349, Percent_Identity=29.512893982808, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787906, Length=270, Percent_Identity=31.8518518518519, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI48994940, Length=314, Percent_Identity=27.3885350318471, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=27.4143302180685, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786540, Length=296, Percent_Identity=28.7162162162162, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790715, Length=309, Percent_Identity=22.9773462783171, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789456, Length=340, Percent_Identity=25, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35551; Mature: 35420

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLAEVAQAAGVTPATVSNVLRNRGRVGALTRERVLAAVEALGYRPHLAARALAEGRAP
CCCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
TIALMVSSIANPFYPEFALAVESALRGSGRYLIICNTENDPGIGRGYLEQIAGTLSEGVL
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCEE
VMNANLDLDDLHATVARGTPVVLCMWERPELPPGLPCVAVDFRLAGELAARHLLALGHRR
EEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
IGALVGSKVSGIHAARCEGFVAALDAAGLDGARAPVRYAPDTIEGGYAAARALLAESPQL
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCE
TALFATNDLPALGAMHAAADAGRRVPDDLSVIGITDIQLAAQSRPALTTVAVPTAEAAAL
EEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEEHEEEECCCCCCEEEEECCCHHHHHH
AVALLAELAGPGGASGEGGAHAAPRMRVTGEPRLVVRASTAPPRGAVA
HHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
PTLAEVAQAAGVTPATVSNVLRNRGRVGALTRERVLAAVEALGYRPHLAARALAEGRAP
CCHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
TIALMVSSIANPFYPEFALAVESALRGSGRYLIICNTENDPGIGRGYLEQIAGTLSEGVL
CHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCEE
VMNANLDLDDLHATVARGTPVVLCMWERPELPPGLPCVAVDFRLAGELAARHLLALGHRR
EEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
IGALVGSKVSGIHAARCEGFVAALDAAGLDGARAPVRYAPDTIEGGYAAARALLAESPQL
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCE
TALFATNDLPALGAMHAAADAGRRVPDDLSVIGITDIQLAAQSRPALTTVAVPTAEAAAL
EEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEEHEEEECCCCCCEEEEECCCHHHHHH
AVALLAELAGPGGASGEGGAHAAPRMRVTGEPRLVVRASTAPPRGAVA
HHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]