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The map label for this gene is dhaR [H]

Identifier: 238027263

GI number: 238027263

Start: 1811778

End: 1812449

Strand: Reverse

Name: dhaR [H]

Synonym: bglu_1g16500

Alternate gene names: 238027263

Gene position: 1812449-1811778 (Counterclockwise)

Preceding gene: 238027264

Following gene: 238027262

Centisome position: 46.4

GC content: 73.07

Gene sequence:

>672_bases
ATGCCCGTGCCATCCGACAAGCCGCGCCGCGGCCGCCCCCCGAAGCACCCGCAGGCCCATGCCGACACGCGCGCCGTGCT
GCTGCGCGCCGGCATGGAGCTGCTGACCGAGCAGGGTTTCACGGCCACCGGGCTCGACACCGTGCTCAAGCGCGTCAACA
TCCCGAAGGGCTCGTTCTATCACTACTTCGCGAGCAAGGACGCGTTCGGCCGCGAGCTGATGGAGGCCTATGACGCGTAT
TTCGCCGCGAAGCTCGACCACTGGCTGCTCGACGGCAGCCGCCCGGCGCTCGCGCGGCTCGCCGCGTTCGTCGCCGACGC
CAAGGCCGGCATGGCGCGCCACGATTTCACGCGCGGCTGCCTGATCGGCAATCTGGGGCTCGAGCTGGGCGCGCTGCCGG
ACGATTTTCGCGACGCGCTCGAACGGATCGTCGCGGGCTGGCAGGCCCGCGTCGCGCGCTGCCTGAGCGACGCGCAGCGC
GAGCGCACGCTCGCGGCCGACGCCGATCTCGACGCGCTCGCCGCGTTCTTCTGGATCGGCTGGGAAGGCGCGGTACTGCG
CGCGCGGCTGGTGCGCAGCGCCACGCCGCTCGACACGTTCTTCAACGGGTTCCTCGCCGGCCTGCCGCGCGCGCGGCCGG
CCCGGGCTCCCGCCCGTCCGCCAGCGGACTGA

Upstream 100 bases:

>100_bases
CGTTATTCCCGCCGCGAGCGAAGGCGTGGCGGCGGGCGGCGCCGGCTGTGCGCCCGCCCCTTCGTTGAATTTCATAGACG
GTCGGTCTAAAATCGGCCGC

Downstream 100 bases:

>100_bases
TTCGCCACCGAGAGACGCACCATGTTCCACTGTCTTCTGATCGACCAGGACGCCGACGGCGCGAGCCGCACGCGCGTCGA
GACGCTCGACGACACCCGCC

Product: Regulatory protein, TetR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MPVPSDKPRRGRPPKHPQAHADTRAVLLRAGMELLTEQGFTATGLDTVLKRVNIPKGSFYHYFASKDAFGRELMEAYDAY
FAAKLDHWLLDGSRPALARLAAFVADAKAGMARHDFTRGCLIGNLGLELGALPDDFRDALERIVAGWQARVARCLSDAQR
ERTLAADADLDALAAFFWIGWEGAVLRARLVRSATPLDTFFNGFLAGLPRARPARAPARPPAD

Sequences:

>Translated_223_residues
MPVPSDKPRRGRPPKHPQAHADTRAVLLRAGMELLTEQGFTATGLDTVLKRVNIPKGSFYHYFASKDAFGRELMEAYDAY
FAAKLDHWLLDGSRPALARLAAFVADAKAGMARHDFTRGCLIGNLGLELGALPDDFRDALERIVAGWQARVARCLSDAQR
ERTLAADADLDALAAFFWIGWEGAVLRARLVRSATPLDTFFNGFLAGLPRARPARAPARPPAD
>Mature_222_residues
PVPSDKPRRGRPPKHPQAHADTRAVLLRAGMELLTEQGFTATGLDTVLKRVNIPKGSFYHYFASKDAFGRELMEAYDAYF
AAKLDHWLLDGSRPALARLAAFVADAKAGMARHDFTRGCLIGNLGLELGALPDDFRDALERIVAGWQARVARCLSDAQRE
RTLAADADLDALAAFFWIGWEGAVLRARLVRSATPLDTFFNGFLAGLPRARPARAPARPPAD

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=185, Percent_Identity=32.972972972973, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24453; Mature: 24322

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPSDKPRRGRPPKHPQAHADTRAVLLRAGMELLTEQGFTATGLDTVLKRVNIPKGSFY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEE
HYFASKDAFGRELMEAYDAYFAAKLDHWLLDGSRPALARLAAFVADAKAGMARHDFTRGC
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LIGNLGLELGALPDDFRDALERIVAGWQARVARCLSDAQRERTLAADADLDALAAFFWIG
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
WEGAVLRARLVRSATPLDTFFNGFLAGLPRARPARAPARPPAD
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVPSDKPRRGRPPKHPQAHADTRAVLLRAGMELLTEQGFTATGLDTVLKRVNIPKGSFY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEE
HYFASKDAFGRELMEAYDAYFAAKLDHWLLDGSRPALARLAAFVADAKAGMARHDFTRGC
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LIGNLGLELGALPDDFRDALERIVAGWQARVARCLSDAQRERTLAADADLDALAAFFWIG
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
WEGAVLRARLVRSATPLDTFFNGFLAGLPRARPARAPARPPAD
CCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]