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The map label for this gene is corA [H]

Identifier: 238027253

GI number: 238027253

Start: 1799233

End: 1800210

Strand: Direct

Name: corA [H]

Synonym: bglu_1g16400

Alternate gene names: 238027253

Gene position: 1799233-1800210 (Clockwise)

Preceding gene: 238027251

Following gene: 238027255

Centisome position: 46.06

GC content: 65.85

Gene sequence:

>978_bases
ATGTTGATCAACTGCGTTGCGTATCAGAACGGCCGGAAGCTGGCCGACATCGAAATCGACGACATCAGCGACTACGTCGC
GCGCCCGGAGTGCTTCGTCTGGGTCGCGCTGAAAGAGCCGAGCCCGGCGGAGCTCGAACGCATGGGCGAGGAGTTCGGCC
TGCACGAGCTGGCGCTGGAGGACGCGCGCAACGGCCACCAGCGCCCGAAGATCGAGGAATACGGCGATTCGCTGTTCGCC
GTGCTGCACACGGTGGAGTTCGACGCCGCCGGCGAGTTCGAGATCGGCGAGCTGAACGTGTTCGTCGGCCCGAACTACGT
CCTGTCGATCCGCAATCACAGCTCGCACGGCTTCCAGGACGTGCGGCTGCGCTGCGAGCGCGAGCCGCACCTGCTGAAGG
AAGGCTCGGCGTTCGTGTTCTACGCGCTGATGGACCAGGTCGTCGATCGCTATTTCCCCACCGTCGAGCGGCTCGGCGCC
GAGCTGGAGGCGTTGGAGGACCGCATCTTCGAGAAGTCGTCGCCGGCCACCGCGCGCGCCATCATCCAGGATCTCTATTC
GCTCAAGCGCCGCCTCGTGACCGTCTACCAGCACACGGCGCCGCTGATCGAACCGCTCTCGAAGCTGGTGGGCGGGCGCA
CGCCGCAGATCTGCAGCGGCATGGAGCATTATTTCCGCGACGTGTACGACCACCTGCAGCGCATCACCAAGACGCTGGAG
GCGCGGCGCGAGATGGTGGTGACGGCGGTGCAGGTGGATCTCGGCATGATCTCGCTCGCCGAGAGCGAGGTGACCAAGCG
GCTCGGCTCGTTCGCCGCGCTGTTCGCGATTCCGACCATGGTGGCCGGGATCTACGGTATGAACTTCAACAACATTCCGG
AGCTGCACTGGCGCTTCGGCTTCTACGCCTGCCTCGGCGTGATGGCGGTGGCCGACCTCGCGCTCTGGTGGCGCTTCCGG
CGCGCCGGCTGGCTGTGA

Upstream 100 bases:

>100_bases
AAGCGCACGCGGTGGCGGGCAGGCGGCTGCGCGCGGGCCGGCGCAGCCGCTACACTAGCGGACCGACTTCAAGACCGAAA
CGGACGTTTCCACCGACACA

Downstream 100 bases:

>100_bases
GCGGGGCCGCCGGCCCTGGCGCGGTCAGCGCTGCGCGTAGCGGCCGGCGGCCACGTTCCAGCGCCGCACCTGCCACTGCC
GCACGAGGCCGTTGCGCACA

Product: Magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLINCVAYQNGRKLADIEIDDISDYVARPECFVWVALKEPSPAELERMGEEFGLHELALEDARNGHQRPKIEEYGDSLFA
VLHTVEFDAAGEFEIGELNVFVGPNYVLSIRNHSSHGFQDVRLRCEREPHLLKEGSAFVFYALMDQVVDRYFPTVERLGA
ELEALEDRIFEKSSPATARAIIQDLYSLKRRLVTVYQHTAPLIEPLSKLVGGRTPQICSGMEHYFRDVYDHLQRITKTLE
ARREMVVTAVQVDLGMISLAESEVTKRLGSFAALFAIPTMVAGIYGMNFNNIPELHWRFGFYACLGVMAVADLALWWRFR
RAGWL

Sequences:

>Translated_325_residues
MLINCVAYQNGRKLADIEIDDISDYVARPECFVWVALKEPSPAELERMGEEFGLHELALEDARNGHQRPKIEEYGDSLFA
VLHTVEFDAAGEFEIGELNVFVGPNYVLSIRNHSSHGFQDVRLRCEREPHLLKEGSAFVFYALMDQVVDRYFPTVERLGA
ELEALEDRIFEKSSPATARAIIQDLYSLKRRLVTVYQHTAPLIEPLSKLVGGRTPQICSGMEHYFRDVYDHLQRITKTLE
ARREMVVTAVQVDLGMISLAESEVTKRLGSFAALFAIPTMVAGIYGMNFNNIPELHWRFGFYACLGVMAVADLALWWRFR
RAGWL
>Mature_325_residues
MLINCVAYQNGRKLADIEIDDISDYVARPECFVWVALKEPSPAELERMGEEFGLHELALEDARNGHQRPKIEEYGDSLFA
VLHTVEFDAAGEFEIGELNVFVGPNYVLSIRNHSSHGFQDVRLRCEREPHLLKEGSAFVFYALMDQVVDRYFPTVERLGA
ELEALEDRIFEKSSPATARAIIQDLYSLKRRLVTVYQHTAPLIEPLSKLVGGRTPQICSGMEHYFRDVYDHLQRITKTLE
ARREMVVTAVQVDLGMISLAESEVTKRLGSFAALFAIPTMVAGIYGMNFNNIPELHWRFGFYACLGVMAVADLALWWRFR
RAGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=302, Percent_Identity=22.8476821192053, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321058, Length=344, Percent_Identity=21.2209302325581, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37051; Mature: 37051

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLINCVAYQNGRKLADIEIDDISDYVARPECFVWVALKEPSPAELERMGEEFGLHELALE
CEEEEEEECCCCEEEEEEHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHH
DARNGHQRPKIEEYGDSLFAVLHTVEFDAAGEFEIGELNVFVGPNYVLSIRNHSSHGFQD
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECEEEEEECCCEEEEEECCCCCCHHH
VRLRCEREPHLLKEGSAFVFYALMDQVVDRYFPTVERLGAELEALEDRIFEKSSPATARA
HHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
IIQDLYSLKRRLVTVYQHTAPLIEPLSKLVGGRTPQICSGMEHYFRDVYDHLQRITKTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARREMVVTAVQVDLGMISLAESEVTKRLGSFAALFAIPTMVAGIYGMNFNNIPELHWRFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FYACLGVMAVADLALWWRFRRAGWL
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLINCVAYQNGRKLADIEIDDISDYVARPECFVWVALKEPSPAELERMGEEFGLHELALE
CEEEEEEECCCCEEEEEEHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCHHHHHHH
DARNGHQRPKIEEYGDSLFAVLHTVEFDAAGEFEIGELNVFVGPNYVLSIRNHSSHGFQD
HHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECEEEEEECCCEEEEEECCCCCCHHH
VRLRCEREPHLLKEGSAFVFYALMDQVVDRYFPTVERLGAELEALEDRIFEKSSPATARA
HHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
IIQDLYSLKRRLVTVYQHTAPLIEPLSKLVGGRTPQICSGMEHYFRDVYDHLQRITKTLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARREMVVTAVQVDLGMISLAESEVTKRLGSFAALFAIPTMVAGIYGMNFNNIPELHWRFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FYACLGVMAVADLALWWRFRRAGWL
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]