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The map label for this gene is mdtA [H]

Identifier: 238026670

GI number: 238026670

Start: 1108293

End: 1109645

Strand: Reverse

Name: mdtA [H]

Synonym: bglu_1g10240

Alternate gene names: 238026670

Gene position: 1109645-1108293 (Counterclockwise)

Preceding gene: 238026671

Following gene: 238026669

Centisome position: 28.41

GC content: 70.73

Gene sequence:

>1353_bases
ATGAATAACCCGGAACCGCAAACGCCTCGCTCCCCCGCCCCCGATCCTCAGGACCCGCCGCCGCGCAACCGCCGGCGGCC
GGTGATGATCGGCGTGGCCGCCGTCGTCGTGGCCGGCGCGGCACTGCTCTGGTGGCAGCCGTGGCGCAAGCCCGCGCCGG
GCGACGGCCAGGCCGCGGGCCAGGCGGGCGGCCGCCGCCACGGCGGGCCGGCCGAGTTCGCGAACCAGCCGCAGCCGGTG
CAGGTCGCCACCGCCACGCGCGGCGAGATGCCGATCGTGCTGTCCGCGCTCGGCACCGTCACGCCGCTCGCCAACGTCAC
GGTCAAGACGCAGCTGTCCGGCTATCTGCAGTCGGTGAACTTCAGAGAAGGCCAGATGGTGAAGAAGGGCGACCTGCTGG
CCCAGATCGATCCGCGCCCCTATCAGGTCGCGCTCGAAACCGCCGAAGGCGCGCTCGCGCGCGACCAGGCCCTGCTCGCC
ACCGCCCGCCTGGACCTGAAGCGCTACCAGACGCTGCTCTCGCAGGATTCGATCGCCCGGCAGACGGTCGACACCCAGGC
CTCGCTCGTCAAGCAATACGAAGGCACCGTCAAGACCGACCAGGCCTCGATCGACTCGGCCAAGCTGAATCTGACCTATG
CGCGCGTGACGGCCCCGGTCTCGGGGCGCGTCGGCCTGCGCCAGGTCGATGCGGGCAACTACGTGACGCCGGGCGACACC
AACGGCATCGTGGTGATCACGCAGCTGCAGCCGATGAGCGTGATCTTCACCACCTCGGAAGACAACCTGCCGCCGATCCT
CAAGCAGGTCAACGCCGGCCGGAAGCTGTCGGTCACGGCCTACAACCGCGACAACACGGTGCCGCTCGAGACGGGCTCGC
TGGAAACCTTCGACAACCAGATCGACACCGCCACCGGCACCTTGAAGCTGCGCGCCACCTTCGCCAACCCGGACAACAAG
CTGTTCCCGAACCAGTTCGTCAACACGCGGCTGCTGGTGGACACGCTGCACGACGCGGTGATCGTGCCGACCGCCGCGGT
GCAGACCGGCTCGATCGGCCAGTTCGTCTACATCGTCAAGCCCGACGACACGGTCACGGTACGCAAGGTCAAGCCCGGCC
CGGTCGACGGCGAGCGCACCAGCATCGCCCAGGGCGTGCAGGTGGGCGAGCGCGTCGTCACCGACGGCGTGGACCGGCTG
CGCGAAGGCGCGAAGATCACCATCCCGGCCGACCATCCGGCCGGCGCATCGGGCGCCGCCGGCGCGGCGGCTGCCGGCGC
CTCGGCGGCACACGCCGGCCGGCGCGCCGGCGGCAATCGCCATCACGGCGCGTCCCAATCCGCCGCGCAATGA

Upstream 100 bases:

>100_bases
CCGGCGCGCGGCGCTCTTTCCGCCCGAGGCGGCCCGCTGCGGCAGCGGGCTCGCGCGGCGCCTCCCTCGCCCGCTCACGT
CAGCGTCAGCCAGATCGAAC

Downstream 100 bases:

>100_bases
CGACGCCTGATCGATGAATCCGTCACGTCTTTTCATCCTCCGCCCGGTCGGCACCGCGCTGCTGATGGCGGCGATCATGC
TGGCGGGCCTGCTCGCGCTG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MNNPEPQTPRSPAPDPQDPPPRNRRRPVMIGVAAVVVAGAALLWWQPWRKPAPGDGQAAGQAGGRRHGGPAEFANQPQPV
QVATATRGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVNFREGQMVKKGDLLAQIDPRPYQVALETAEGALARDQALLA
TARLDLKRYQTLLSQDSIARQTVDTQASLVKQYEGTVKTDQASIDSAKLNLTYARVTAPVSGRVGLRQVDAGNYVTPGDT
NGIVVITQLQPMSVIFTTSEDNLPPILKQVNAGRKLSVTAYNRDNTVPLETGSLETFDNQIDTATGTLKLRATFANPDNK
LFPNQFVNTRLLVDTLHDAVIVPTAAVQTGSIGQFVYIVKPDDTVTVRKVKPGPVDGERTSIAQGVQVGERVVTDGVDRL
REGAKITIPADHPAGASGAAGAAAAGASAAHAGRRAGGNRHHGASQSAAQ

Sequences:

>Translated_450_residues
MNNPEPQTPRSPAPDPQDPPPRNRRRPVMIGVAAVVVAGAALLWWQPWRKPAPGDGQAAGQAGGRRHGGPAEFANQPQPV
QVATATRGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVNFREGQMVKKGDLLAQIDPRPYQVALETAEGALARDQALLA
TARLDLKRYQTLLSQDSIARQTVDTQASLVKQYEGTVKTDQASIDSAKLNLTYARVTAPVSGRVGLRQVDAGNYVTPGDT
NGIVVITQLQPMSVIFTTSEDNLPPILKQVNAGRKLSVTAYNRDNTVPLETGSLETFDNQIDTATGTLKLRATFANPDNK
LFPNQFVNTRLLVDTLHDAVIVPTAAVQTGSIGQFVYIVKPDDTVTVRKVKPGPVDGERTSIAQGVQVGERVVTDGVDRL
REGAKITIPADHPAGASGAAGAAAAGASAAHAGRRAGGNRHHGASQSAAQ
>Mature_450_residues
MNNPEPQTPRSPAPDPQDPPPRNRRRPVMIGVAAVVVAGAALLWWQPWRKPAPGDGQAAGQAGGRRHGGPAEFANQPQPV
QVATATRGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVNFREGQMVKKGDLLAQIDPRPYQVALETAEGALARDQALLA
TARLDLKRYQTLLSQDSIARQTVDTQASLVKQYEGTVKTDQASIDSAKLNLTYARVTAPVSGRVGLRQVDAGNYVTPGDT
NGIVVITQLQPMSVIFTTSEDNLPPILKQVNAGRKLSVTAYNRDNTVPLETGSLETFDNQIDTATGTLKLRATFANPDNK
LFPNQFVNTRLLVDTLHDAVIVPTAAVQTGSIGQFVYIVKPDDTVTVRKVKPGPVDGERTSIAQGVQVGERVVTDGVDRL
REGAKITIPADHPAGASGAAGAAAAGASAAHAGRRAGGNRHHGASQSAAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=374, Percent_Identity=47.8609625668449, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI1789929, Length=321, Percent_Identity=31.1526479750779, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789665, Length=316, Percent_Identity=33.5443037974684, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1786668, Length=378, Percent_Identity=32.010582010582, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081951, Length=133, Percent_Identity=34.5864661654135, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081796, Length=208, Percent_Identity=29.8076923076923, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47524; Mature: 47524

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPEPQTPRSPAPDPQDPPPRNRRRPVMIGVAAVVVAGAALLWWQPWRKPAPGDGQAAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCC
QAGGRRHGGPAEFANQPQPVQVATATRGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVN
CCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHCCC
FREGQMVKKGDLLAQIDPRPYQVALETAEGALARDQALLATARLDLKRYQTLLSQDSIAR
CCCCCEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTVDTQASLVKQYEGTVKTDQASIDSAKLNLTYARVTAPVSGRVGLRQVDAGNYVTPGDT
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEECCCCEECCCCC
NGIVVITQLQPMSVIFTTSEDNLPPILKQVNAGRKLSVTAYNRDNTVPLETGSLETFDNQ
CCEEEEEECCCEEEEEECCCCCCCHHHHHCCCCCEEEEEEECCCCEEEECCCCCHHHCCC
IDTATGTLKLRATFANPDNKLFPNQFVNTRLLVDTLHDAVIVPTAAVQTGSIGQFVYIVK
CCCCCEEEEEEEEECCCCCCCCCCHHCCHHHEEHHHCCEEEECCCEECCCCCCEEEEEEC
PDDTVTVRKVKPGPVDGERTSIAQGVQVGERVVTDGVDRLREGAKITIPADHPAGASGAA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
GAAAAGASAAHAGRRAGGNRHHGASQSAAQ
CHHHCCCHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNNPEPQTPRSPAPDPQDPPPRNRRRPVMIGVAAVVVAGAALLWWQPWRKPAPGDGQAAG
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHEEECCCCCCCCCCCCCCC
QAGGRRHGGPAEFANQPQPVQVATATRGEMPIVLSALGTVTPLANVTVKTQLSGYLQSVN
CCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHCCC
FREGQMVKKGDLLAQIDPRPYQVALETAEGALARDQALLATARLDLKRYQTLLSQDSIAR
CCCCCEEECCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTVDTQASLVKQYEGTVKTDQASIDSAKLNLTYARVTAPVSGRVGLRQVDAGNYVTPGDT
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEECCCCEECCCCC
NGIVVITQLQPMSVIFTTSEDNLPPILKQVNAGRKLSVTAYNRDNTVPLETGSLETFDNQ
CCEEEEEECCCEEEEEECCCCCCCHHHHHCCCCCEEEEEEECCCCEEEECCCCCHHHCCC
IDTATGTLKLRATFANPDNKLFPNQFVNTRLLVDTLHDAVIVPTAAVQTGSIGQFVYIVK
CCCCCEEEEEEEEECCCCCCCCCCHHCCHHHEEHHHCCEEEECCCEECCCCCCEEEEEEC
PDDTVTVRKVKPGPVDGERTSIAQGVQVGERVVTDGVDRLREGAKITIPADHPAGASGAA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
GAAAAGASAAHAGRRAGGNRHHGASQSAAQ
CHHHCCCHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA