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The map label for this gene is otsA [H]

Identifier: 238026637

GI number: 238026637

Start: 1061831

End: 1063234

Strand: Direct

Name: otsA [H]

Synonym: bglu_1g09890

Alternate gene names: 238026637

Gene position: 1061831-1063234 (Clockwise)

Preceding gene: 238026636

Following gene: 238026639

Centisome position: 27.18

GC content: 69.23

Gene sequence:

>1404_bases
ATGAGCCGGCTGATCATCGTATCGAATCGGGTCGCGCCGATCTCCGAGGGCGAACCGGCCGCGGGCGGCCTCGCTATCGG
CGTCTACGACGCGCTCAAGGAAACCGGCGGCATGTGGTTCGGCTGGAGCGGCGAGGTGGTCGCCTCGGGCGCGCCGCAGA
TCCGCGTGGAGGAGCGCGGCCCCGTGACGTTTGCCACGATCGGCCTCGTGCGCCGCGATTACGACCAGTACTATCGCGGC
TTCTCGAACGCGACGCTATGGCCCGCGTTCCACTACCGGACCGATCTGATCCAGTACGACCGCCACGAATTCGAGGGCTA
TGGCCGCGTCAACGTCTGGCTCGCGCAGCAACTGGTGCCGCTGCTGCGCGACGACGACGTGATCTGGGTCCACGACTATC
ACCTGATTCCGTTCGCGCAGGCGCTGCGCGCGGCCGGCGTGAAGAACCGGATCGGCTTCTTCCTGCATATCCCGTTTCCG
GCCGCCGAGGTGCTCGTCAACGTGCCGCCGCACCGCATGCTGGTCGAGGCGATGTGCTCGTACGACCTGCTCGGCTTCCA
GACCGAGCCGGACTTGCGCGCGTTCTGCGACTACATCGACGCGGAGGCGCAGGGCAGCCTCGAGCGCGGCGGCGCGCCCG
GCATCCGCGGCAGCGGCCCGGTGACGATCCGCGCGTTCGGCCGCGTGCTGCAGGCGCATGCCTATCCGATCGGCATCTAT
CCCGACGAGATCGCCTCGCTCGCGCAGGCGGGCGCCAACGGCCGCGCGGTGCGTACGCTCGCCACCTCGCTGCACGGGCG
GCAGCTCGTGATGAGCGTGGATCGCCTCGATTACTCGAAGGGGCTCGTCGAGCGCTTCCGCGCGTTCGAGAAGCTGCTCG
AGCACGAGGCGTCGTACCGCAACCGCGTGTCGTTCCTGCAGATCGCGCCGTCCACGCGCGCGGACCTGCGCGCCTACCAG
GACATCCGGCTGCAGCTCGAAGGCGAGTCGGGGCGCATCAACGGCCGTTACGCGGAGCTCGACTGGGCGCCGATCCTCTA
CATCCACCGGCAGTACGAACGGCCGCTGCTCGCCGCGCTGTACCGGCTCGCGCGCGTCGGCTTCGTGACGCCGCTGCGCG
ACGGCATGAACCTGGTCGCGAAGGAATACGTGTCGGCGCAGGACCCCGAGGACCCGGGCGTGCTGGTGCTGTCGCGCTTC
GCGGGTGCCGCGCGCGAGCTGACGGGCGCGCTGATCGTCAATCCGATGGATATCGACAGCATGGCCGAGGCGCTCTCGCA
GGCGCTGTCGATGCCGGTGGCCGAGCGCCGCGCGCGCTACACCGAGATGATCGCGCAGCTGCGCGAGAACAACGTCTCGG
TCTGGCGCGACAACTTCCTGCGCGATCTGCAGAGGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGATTGGCGCGGGCGATACCACGGCGCGCGCACGGCTCGATTCGGTCGAGGCGATGCGCGCGCAGATCGCCGCCTGGATT
GCGGCGGAGCCCGCCCGCGC

Downstream 100 bases:

>100_bases
GCCGCGCGTCCATGAAAAAACCGCCGGCTGGACCGGCGGTTTTCGTCTCGGCTGGGCGGTGCGTCAGGCGACGCGTTCGT
CGCCGAGCGTCGCGTCGTCG

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRVEERGPVTFATIGLVRRDYDQYYRG
FSNATLWPAFHYRTDLIQYDRHEFEGYGRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFAQALRAAGVKNRIGFFLHIPFP
AAEVLVNVPPHRMLVEAMCSYDLLGFQTEPDLRAFCDYIDAEAQGSLERGGAPGIRGSGPVTIRAFGRVLQAHAYPIGIY
PDEIASLAQAGANGRAVRTLATSLHGRQLVMSVDRLDYSKGLVERFRAFEKLLEHEASYRNRVSFLQIAPSTRADLRAYQ
DIRLQLEGESGRINGRYAELDWAPILYIHRQYERPLLAALYRLARVGFVTPLRDGMNLVAKEYVSAQDPEDPGVLVLSRF
AGAARELTGALIVNPMDIDSMAEALSQALSMPVAERRARYTEMIAQLRENNVSVWRDNFLRDLQRAG

Sequences:

>Translated_467_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRVEERGPVTFATIGLVRRDYDQYYRG
FSNATLWPAFHYRTDLIQYDRHEFEGYGRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFAQALRAAGVKNRIGFFLHIPFP
AAEVLVNVPPHRMLVEAMCSYDLLGFQTEPDLRAFCDYIDAEAQGSLERGGAPGIRGSGPVTIRAFGRVLQAHAYPIGIY
PDEIASLAQAGANGRAVRTLATSLHGRQLVMSVDRLDYSKGLVERFRAFEKLLEHEASYRNRVSFLQIAPSTRADLRAYQ
DIRLQLEGESGRINGRYAELDWAPILYIHRQYERPLLAALYRLARVGFVTPLRDGMNLVAKEYVSAQDPEDPGVLVLSRF
AGAARELTGALIVNPMDIDSMAEALSQALSMPVAERRARYTEMIAQLRENNVSVWRDNFLRDLQRAG
>Mature_466_residues
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRVEERGPVTFATIGLVRRDYDQYYRGF
SNATLWPAFHYRTDLIQYDRHEFEGYGRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFAQALRAAGVKNRIGFFLHIPFPA
AEVLVNVPPHRMLVEAMCSYDLLGFQTEPDLRAFCDYIDAEAQGSLERGGAPGIRGSGPVTIRAFGRVLQAHAYPIGIYP
DEIASLAQAGANGRAVRTLATSLHGRQLVMSVDRLDYSKGLVERFRAFEKLLEHEASYRNRVSFLQIAPSTRADLRAYQD
IRLQLEGESGRINGRYAELDWAPILYIHRQYERPLLAALYRLARVGFVTPLRDGMNLVAKEYVSAQDPEDPGVLVLSRFA
GAARELTGALIVNPMDIDSMAEALSQALSMPVAERRARYTEMIAQLRENNVSVWRDNFLRDLQRAG

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=465, Percent_Identity=52.0430107526882, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI115533558, Length=420, Percent_Identity=28.3333333333333, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115533560, Length=420, Percent_Identity=28.3333333333333, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71987012, Length=437, Percent_Identity=28.1464530892449, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6319602, Length=477, Percent_Identity=30.8176100628931, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6323537, Length=443, Percent_Identity=26.410835214447, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320279, Length=425, Percent_Identity=25.8823529411765, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323917, Length=408, Percent_Identity=24.2647058823529, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19920676, Length=493, Percent_Identity=33.8742393509128, Blast_Score=263, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52265; Mature: 52134

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRVEERG
CCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCEEECCCCEEEEECCC
PVTFATIGLVRRDYDQYYRGFSNATLWPAFHYRTDLIQYDRHEFEGYGRVNVWLAQQLVP
CEEEEHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHH
LLRDDDVIWVHDYHLIPFAQALRAAGVKNRIGFFLHIPFPAAEVLVNVPPHRMLVEAMCS
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEECCCCHHHHHHHHHH
YDLLGFQTEPDLRAFCDYIDAEAQGSLERGGAPGIRGSGPVTIRAFGRVLQAHAYPIGIY
HHHCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCEEHHHHHHHHHHCCCEECCC
PDEIASLAQAGANGRAVRTLATSLHGRQLVMSVDRLDYSKGLVERFRAFEKLLEHEASYR
HHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRVSFLQIAPSTRADLRAYQDIRLQLEGESGRINGRYAELDWAPILYIHRQYERPLLAAL
CCCEEEEECCCCHHHHHHCEEEEEEEECCCCCCCCEEEECCCCEEEEEHHHHCCHHHHHH
YRLARVGFVTPLRDGMNLVAKEYVSAQDPEDPGVLVLSRFAGAARELTGALIVNPMDIDS
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCHHHHHCCEEEECCCCHHH
MAEALSQALSMPVAERRARYTEMIAQLRENNVSVWRDNFLRDLQRAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVVASGAPQIRVEERG
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCEEECCCCEEEEECCC
PVTFATIGLVRRDYDQYYRGFSNATLWPAFHYRTDLIQYDRHEFEGYGRVNVWLAQQLVP
CEEEEHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHH
LLRDDDVIWVHDYHLIPFAQALRAAGVKNRIGFFLHIPFPAAEVLVNVPPHRMLVEAMCS
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEECCCCHHHHHHHHHH
YDLLGFQTEPDLRAFCDYIDAEAQGSLERGGAPGIRGSGPVTIRAFGRVLQAHAYPIGIY
HHHCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCEEHHHHHHHHHHCCCEECCC
PDEIASLAQAGANGRAVRTLATSLHGRQLVMSVDRLDYSKGLVERFRAFEKLLEHEASYR
HHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRVSFLQIAPSTRADLRAYQDIRLQLEGESGRINGRYAELDWAPILYIHRQYERPLLAAL
CCCEEEEECCCCHHHHHHCEEEEEEEECCCCCCCCEEEECCCCEEEEEHHHHCCHHHHHH
YRLARVGFVTPLRDGMNLVAKEYVSAQDPEDPGVLVLSRFAGAARELTGALIVNPMDIDS
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHCCHHHHHCCEEEECCCCHHH
MAEALSQALSMPVAERRARYTEMIAQLRENNVSVWRDNFLRDLQRAG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA