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The map label for this gene is moeA [H]

Identifier: 238026591

GI number: 238026591

Start: 1012888

End: 1014153

Strand: Reverse

Name: moeA [H]

Synonym: bglu_1g09370

Alternate gene names: 238026591

Gene position: 1014153-1012888 (Counterclockwise)

Preceding gene: 238026592

Following gene: 238026590

Centisome position: 25.96

GC content: 75.99

Gene sequence:

>1266_bases
ATGACCACGCCACCGTCGCCCGAAACCCTGTCCGTCGAAGCCGCGCGCATGCTTGCGCTGCAAGCGATCGTGCCGGTCGC
GGAAACGGAGCGCGTCGCGCTGCACGACGCGCTCGGCCGCGTGCTCGCCGACGCCGTCACCTCACCGCTCGACGTGCCCG
CCTACGACAACGCCGCCATGGACGGCTACGCGTTCGCCGGCGCCGCGCTCGCGCACGCGGCAGGCGCCGAACTCGCCCTG
CCGGTCGCCGGCATCGCGCTGGCCGGCCATCCCCACGCGGGCCCCCTGCCGCCCGGCGCCTGCATCCGGATCATGACGGG
TGCGCCGCTGCCCGCCGGCAGCGACACCGTGATCGCACAGGAGCGCACAAACGCGACCGACACGCTGGTGCGCTTCGCGG
CGAACGCGGTCACGCCCGGCGCGAACTGCCGCCGCGCCGGGGAGGATCTCGCACGCGGCGCGATCGTCCTGGAAGCGGGC
AGGATCGTGCGGCCCGCCGATCTCGGCCTGCTCGCCTCGCTCGGCATCGGCCACATCGAAGTGCGGCGCCGGCTGCGCGT
GGCGTGCCTGTCGACGGGCGACGAGCTGCGCGCGCCGGGCGAGCCGCTCGGTGCCGGCGGCCGTTACGACAGCAACCGCG
CGACGCTGTACGGGATGCTCGCGGCGCTCGGCGTCGACGTGCTGGACGGCGGGATCGTCCGCGACGATCCCGCCGCGCTC
GAGGCGGCGCTGCGCGAGGCGGCCATGCGCGCCGACGTGGTGATCACCTCCGGCGGCGTGTCGGTGGGCGACGCCGATTT
CACGCGCGGACTGCTCGGCCGCCTCGGCGAGATCCGCTTCGCGAACCTCGCGATGCGGCCCGGCCGGCCGCTCGCCTGCG
GGCGCTTCGCGCCGCCCGAGCCGGGCGCGCGCGCGGCGCTGTTCTTCGGGCTGCCGGGCAACCCGGTGGCGGTGGCCGCG
ACGTTCCAGGTAATCGTGCGCGACGCGCTGCTCGCCATGATGGGCGCGCGGGCCGAGCCGGCGCCGCGCTATCCGGCCCG
CACCAGCGCGGCGATCGACACGCGCGCGGGCCGCACCGATTTCCTGCGCGGCGTGGCTAGCCGCGAGCCGGACGGCGCGT
GGCGCGTCGCGCCGGCGGGCTCGCAGAGTTCGGCGTCGCTGAAGGGCCTCAGCGACGCGAACTGCTTCATCGTCGTGGGC
GCCGGCCTCGCCCGCGTCGAGGCCGGCGACAGCGTCGAGATCCTGCCATTCGCCGGCGCACTCTGA

Upstream 100 bases:

>100_bases
CCGCCGCCGCCCGCCTCCGTCGGCGCGTCCTGCCGCTGCGGCACGCTGCTGCCGCCTGCCGGCGTGAACCCGATCCCAGC
CTTGCGGCGCTCCTTCAGCC

Downstream 100 bases:

>100_bases
GCAACAATTATTTTCAGCACTTACGGGGCAATTCGATCATGAAAAAGCAAATCTCCTCGATCGCGGCGGGACAGACGGCC
AAGGCACTGATCCTCGTCTA

Product: molybdopterin biosynthesis moeA protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTTPPSPETLSVEAARMLALQAIVPVAETERVALHDALGRVLADAVTSPLDVPAYDNAAMDGYAFAGAALAHAAGAELAL
PVAGIALAGHPHAGPLPPGACIRIMTGAPLPAGSDTVIAQERTNATDTLVRFAANAVTPGANCRRAGEDLARGAIVLEAG
RIVRPADLGLLASLGIGHIEVRRRLRVACLSTGDELRAPGEPLGAGGRYDSNRATLYGMLAALGVDVLDGGIVRDDPAAL
EAALREAAMRADVVITSGGVSVGDADFTRGLLGRLGEIRFANLAMRPGRPLACGRFAPPEPGARAALFFGLPGNPVAVAA
TFQVIVRDALLAMMGARAEPAPRYPARTSAAIDTRAGRTDFLRGVASREPDGAWRVAPAGSQSSASLKGLSDANCFIVVG
AGLARVEAGDSVEILPFAGAL

Sequences:

>Translated_421_residues
MTTPPSPETLSVEAARMLALQAIVPVAETERVALHDALGRVLADAVTSPLDVPAYDNAAMDGYAFAGAALAHAAGAELAL
PVAGIALAGHPHAGPLPPGACIRIMTGAPLPAGSDTVIAQERTNATDTLVRFAANAVTPGANCRRAGEDLARGAIVLEAG
RIVRPADLGLLASLGIGHIEVRRRLRVACLSTGDELRAPGEPLGAGGRYDSNRATLYGMLAALGVDVLDGGIVRDDPAAL
EAALREAAMRADVVITSGGVSVGDADFTRGLLGRLGEIRFANLAMRPGRPLACGRFAPPEPGARAALFFGLPGNPVAVAA
TFQVIVRDALLAMMGARAEPAPRYPARTSAAIDTRAGRTDFLRGVASREPDGAWRVAPAGSQSSASLKGLSDANCFIVVG
AGLARVEAGDSVEILPFAGAL
>Mature_420_residues
TTPPSPETLSVEAARMLALQAIVPVAETERVALHDALGRVLADAVTSPLDVPAYDNAAMDGYAFAGAALAHAAGAELALP
VAGIALAGHPHAGPLPPGACIRIMTGAPLPAGSDTVIAQERTNATDTLVRFAANAVTPGANCRRAGEDLARGAIVLEAGR
IVRPADLGLLASLGIGHIEVRRRLRVACLSTGDELRAPGEPLGAGGRYDSNRATLYGMLAALGVDVLDGGIVRDDPAALE
AALREAAMRADVVITSGGVSVGDADFTRGLLGRLGEIRFANLAMRPGRPLACGRFAPPEPGARAALFFGLPGNPVAVAAT
FQVIVRDALLAMMGARAEPAPRYPARTSAAIDTRAGRTDFLRGVASREPDGAWRVAPAGSQSSASLKGLSDANCFIVVGA
GLARVEAGDSVEILPFAGAL

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=426, Percent_Identity=32.6291079812207, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI66932975, Length=426, Percent_Identity=32.6291079812207, Blast_Score=175, Evalue=9e-44,
Organism=Escherichia coli, GI1787049, Length=391, Percent_Identity=46.5473145780051, Blast_Score=326, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI25147659, Length=378, Percent_Identity=31.2169312169312, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17562606, Length=369, Percent_Identity=25.2032520325203, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17136978, Length=319, Percent_Identity=29.7805642633229, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24638841, Length=319, Percent_Identity=29.7805642633229, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 42865; Mature: 42733

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPSPETLSVEAARMLALQAIVPVAETERVALHDALGRVLADAVTSPLDVPAYDNAAM
CCCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DGYAFAGAALAHAAGAELALPVAGIALAGHPHAGPLPPGACIRIMTGAPLPAGSDTVIAQ
CCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
ERTNATDTLVRFAANAVTPGANCRRAGEDLARGAIVLEAGRIVRPADLGLLASLGIGHIE
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCEECCCCHHHHHHCCCCHHH
VRRRLRVACLSTGDELRAPGEPLGAGGRYDSNRATLYGMLAALGVDVLDGGIVRDDPAAL
HHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
EAALREAAMRADVVITSGGVSVGDADFTRGLLGRLGEIRFANLAMRPGRPLACGRFAPPE
HHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCC
PGARAALFFGLPGNPVAVAATFQVIVRDALLAMMGARAEPAPRYPARTSAAIDTRAGRTD
CCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCHHH
FLRGVASREPDGAWRVAPAGSQSSASLKGLSDANCFIVVGAGLARVEAGDSVEILPFAGA
HHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCEEEEECCCC
L
C
>Mature Secondary Structure 
TTPPSPETLSVEAARMLALQAIVPVAETERVALHDALGRVLADAVTSPLDVPAYDNAAM
CCCCCCCEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
DGYAFAGAALAHAAGAELALPVAGIALAGHPHAGPLPPGACIRIMTGAPLPAGSDTVIAQ
CCHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCEEEE
ERTNATDTLVRFAANAVTPGANCRRAGEDLARGAIVLEAGRIVRPADLGLLASLGIGHIE
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCEECCCCHHHHHHCCCCHHH
VRRRLRVACLSTGDELRAPGEPLGAGGRYDSNRATLYGMLAALGVDVLDGGIVRDDPAAL
HHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHH
EAALREAAMRADVVITSGGVSVGDADFTRGLLGRLGEIRFANLAMRPGRPLACGRFAPPE
HHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCC
PGARAALFFGLPGNPVAVAATFQVIVRDALLAMMGARAEPAPRYPARTSAAIDTRAGRTD
CCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCHHH
FLRGVASREPDGAWRVAPAGSQSSASLKGLSDANCFIVVGAGLARVEAGDSVEILPFAGA
HHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCEEEEECCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]