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The map label for this gene is cysM [H]

Identifier: 238026544

GI number: 238026544

Start: 965912

End: 966814

Strand: Direct

Name: cysM [H]

Synonym: bglu_1g08880

Alternate gene names: 238026544

Gene position: 965912-966814 (Clockwise)

Preceding gene: 238026543

Following gene: 238026546

Centisome position: 24.73

GC content: 67.33

Gene sequence:

>903_bases
ATGGCTTACAAGACTATCGAAGACACGATCGGCAACACGCCGCTCGTGCAACTCGTGCGGATCCCCGACGACGAGATCCG
GGCCCGCAACAACGTGATCCTCGCGAAGCTCGAAGGCAACAATCCCGCCGGCTCGGTCAAGGACCGCCCGGCGCTGTCGA
TGATCCGCAAGGCCGAGGAACGCGGGCGCATCAAGCCCGGCGACACGCTGATCGAGGCGACGAGCGGCAACACCGGCATC
GCGCTGGCGATGGCGGCCGCGATCCGCGGCTACCGGATGGTGCTGATCATGCCCGAGGACCTGTCGGTCGAGCGCCGCCA
GAGCATGGCCGCCTACGGCGCGGAAATCGTGCTGACGCCGACCAAGGGCGGCATGGAACTCGCGCGCGATCTCGCCGACC
AGATGCAGCGCGAAGGCAAGGGCGTGATCCTCGACCAGTTCGCGAATCCGGACAATCCGCTCGCGCACTACGAGACGACC
GGCCCGGAAATCTGGCGTGAAACCGAAGGCCGCATCACGCATTTCGTCTCGGCGATGGGGACCACGGGCACCATCATGGG
CACCACGCAGTTCCTGAAGGAGCAGCGCCAGAGCATCGAGATCGTCGGTGCGCAGCCGGAGGAAGGCTCGCGCATTCCCG
GCATCCGCAAGTGGCCCGAGGCCTACCTGCCGAAGATCTTCGATCGCAGCCGCATCGACCGCGTCGAGAACGTCAGCCAG
GCCGCCTCCGAGGCGATGGCGCGCAAGCTCGCCGCGACCGAGGGCCTGTTCTGCGGCATCTCGACGGGCGGCGCCTGCGA
GGTGGCGATGCGCATCGCGCGGCAGGTCGAGAACGCGACGATCGTGTTCATCGCCTGCGACCGCGGCGACCGCTATCTGT
CGACGGGCGTGTTCCCCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCCGGACGCGGGCAGGGACATTCCCGGTGCCGATACGACCGATCCGGCGCTGGATTACAATCGACAGATTCATCGGC
CTCGTATTCACTTATCGCCC

Downstream 100 bases:

>100_bases
GTGCCGCAAGCGGCTCGCTGCCGTCTTCGCCCAAGAAAAAAGCGCCACGAGGGCGCTTTTTTCATGGGTCCGGCGAGGTG
CCTGGGCCTCACTGCGTGGC

Product: cysteine synthase B

Products: NA

Alternate protein names: CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAYKTIEDTIGNTPLVQLVRIPDDEIRARNNVILAKLEGNNPAGSVKDRPALSMIRKAEERGRIKPGDTLIEATSGNTGI
ALAMAAAIRGYRMVLIMPEDLSVERRQSMAAYGAEIVLTPTKGGMELARDLADQMQREGKGVILDQFANPDNPLAHYETT
GPEIWRETEGRITHFVSAMGTTGTIMGTTQFLKEQRQSIEIVGAQPEEGSRIPGIRKWPEAYLPKIFDRSRIDRVENVSQ
AASEAMARKLAATEGLFCGISTGGACEVAMRIARQVENATIVFIACDRGDRYLSTGVFPA

Sequences:

>Translated_300_residues
MAYKTIEDTIGNTPLVQLVRIPDDEIRARNNVILAKLEGNNPAGSVKDRPALSMIRKAEERGRIKPGDTLIEATSGNTGI
ALAMAAAIRGYRMVLIMPEDLSVERRQSMAAYGAEIVLTPTKGGMELARDLADQMQREGKGVILDQFANPDNPLAHYETT
GPEIWRETEGRITHFVSAMGTTGTIMGTTQFLKEQRQSIEIVGAQPEEGSRIPGIRKWPEAYLPKIFDRSRIDRVENVSQ
AASEAMARKLAATEGLFCGISTGGACEVAMRIARQVENATIVFIACDRGDRYLSTGVFPA
>Mature_299_residues
AYKTIEDTIGNTPLVQLVRIPDDEIRARNNVILAKLEGNNPAGSVKDRPALSMIRKAEERGRIKPGDTLIEATSGNTGIA
LAMAAAIRGYRMVLIMPEDLSVERRQSMAAYGAEIVLTPTKGGMELARDLADQMQREGKGVILDQFANPDNPLAHYETTG
PEIWRETEGRITHFVSAMGTTGTIMGTTQFLKEQRQSIEIVGAQPEEGSRIPGIRKWPEAYLPKIFDRSRIDRVENVSQA
ASEAMARKLAATEGLFCGISTGGACEVAMRIARQVENATIVFIACDRGDRYLSTGVFPA

Specific function: Two Cysteine Synthase Enzymes Are Found. Both Catalyze The Same Reaction. Cysteine Synthase B Can Also Use Thiosulfate In Place Of Sulfide To Give Cysteine Thiosulfonate As A Product. [C]

COG id: COG0031

COG function: function code E; Cysteine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cysteine synthase/cystathionine beta- synthase family [H]

Homologues:

Organism=Homo sapiens, GI295821202, Length=302, Percent_Identity=39.0728476821192, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI295821200, Length=302, Percent_Identity=39.0728476821192, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4557415, Length=302, Percent_Identity=39.0728476821192, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI2367138, Length=295, Percent_Identity=62.3728813559322, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788754, Length=317, Percent_Identity=40.0630914826498, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17535051, Length=305, Percent_Identity=41.6393442622951, Blast_Score=213, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI17562970, Length=302, Percent_Identity=41.0596026490066, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32566674, Length=297, Percent_Identity=41.7508417508418, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI115535073, Length=300, Percent_Identity=39.6666666666667, Blast_Score=200, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17561720, Length=302, Percent_Identity=39.0728476821192, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17534315, Length=317, Percent_Identity=36.2776025236593, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25147552, Length=318, Percent_Identity=34.9056603773585, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI32566672, Length=212, Percent_Identity=35.377358490566, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321594, Length=319, Percent_Identity=38.5579937304075, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6321449, Length=333, Percent_Identity=33.9339339339339, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24643623, Length=311, Percent_Identity=38.5852090032154, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI20129101, Length=311, Percent_Identity=38.5852090032154, Blast_Score=171, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001216
- InterPro:   IPR005856
- InterPro:   IPR005858
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =2.5.1.47 [H]

Molecular weight: Translated: 32766; Mature: 32635

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00901 CYS_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKTIEDTIGNTPLVQLVRIPDDEIRARNNVILAKLEGNNPAGSVKDRPALSMIRKAEE
CCCCCHHHHCCCCCEEEEEECCCHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
RGRIKPGDTLIEATSGNTGIALAMAAAIRGYRMVLIMPEDLSVERRQSMAAYGAEIVLTP
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEC
TKGGMELARDLADQMQREGKGVILDQFANPDNPLAHYETTGPEIWRETEGRITHFVSAMG
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCHHHHHHCCCHHHHHHHHHC
TTGTIMGTTQFLKEQRQSIEIVGAQPEEGSRIPGIRKWPEAYLPKIFDRSRIDRVENVSQ
CCCEEHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AASEAMARKLAATEGLFCGISTGGACEVAMRIARQVENATIVFIACDRGDRYLSTGVFPA
HHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
AYKTIEDTIGNTPLVQLVRIPDDEIRARNNVILAKLEGNNPAGSVKDRPALSMIRKAEE
CCCCHHHHCCCCCEEEEEECCCHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHH
RGRIKPGDTLIEATSGNTGIALAMAAAIRGYRMVLIMPEDLSVERRQSMAAYGAEIVLTP
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEC
TKGGMELARDLADQMQREGKGVILDQFANPDNPLAHYETTGPEIWRETEGRITHFVSAMG
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCHHHHHHCCCHHHHHHHHHC
TTGTIMGTTQFLKEQRQSIEIVGAQPEEGSRIPGIRKWPEAYLPKIFDRSRIDRVENVSQ
CCCEEHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AASEAMARKLAATEGLFCGISTGGACEVAMRIARQVENATIVFIACDRGDRYLSTGVFPA
HHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]