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The map label for this gene is ribB [H]

Identifier: 238026452

GI number: 238026452

Start: 853441

End: 854568

Strand: Reverse

Name: ribB [H]

Synonym: bglu_1g07940

Alternate gene names: 238026452

Gene position: 854568-853441 (Counterclockwise)

Preceding gene: 238026453

Following gene: 238026451

Centisome position: 21.88

GC content: 69.33

Gene sequence:

>1128_bases
ATGACGCTCGCCTCCACGCCCGACATCATCGCCGAGCTGAAAGCCGGCCGGATGGTGATCCTCGTCGACGAAGAAGATCG
CGAAAACGAAGGCGATCTGGTCATCGCGGCCGAATTCGTCACGCCGGAAGCGATCAATTTCATGGCGCGCTACGGCCGCG
GCCTGATTTGCCTGACCCTCACGCAGGAGCGCTGCAAGGCGCTGAACCTGCCGCTCATGACCTACCGCAACGGCACGCAG
TACGGCACCGCGTTCACGGTCAGCATCGAGGCGGCCGAGGGGGTGACCACCGGCATCTCGGCGGCCGACCGGGCCCACAC
GATCGCCACGGCCGTCAAGCGCGACGCGCGCGCCGACGAGATCGTCCAGCCCGGCCACGTGTTCCCGATCATGGCGCAGC
CGGGCGGCGTGCTGGTGCGCGCGGGCCACACCGAGGCCGGCTGCGACCTCACGGCGCTCGCGGGCCTCACGCCGGCGGCG
GTGATCTGCGAGGTCATCAAGGACGACGGCTCGATGGCGCGCCTGCCCGACCTGATCGCGTTCAGCCAGGAACACGGCCT
CAAGATCGGCACGATCGCCGACCTGATCCACTACCGCAGCCGCACCGAATCGATCGTCGAGCGCGTGGCCGAGCGCACCA
TGCAGACTGCGCACGGCGCGTTCCAGGCCGTGCTCTATCGCGACAAGCCCACCGGCTCGCCGCACATCGCGCTGGTGCGC
GGCACGCCCACGCCCGACCGCGAAACGCCGGTGCGCGTCCACGAACCGCTCTCGGTGCTCGACCTGCTCGAAACCAGCAG
CTCGACGCACTCGTGGACGCTCGACGCGGCCATGAAGGAGATCGCCGAGCGCGATCTCGGTGCGATCGTGCTGCTGAACT
GCGGCGACACGAAGGAGCATCTCGTCGAGGTGTTCCGCGCGTTCGACGAGGAGGAAAAGGCCGCGGTGCTCAAGCGCCGC
CCGGTCGACTTCAAGACGTTCGGCATCGGCGCGCAGATCCTGCGCGACGTCGGCGTCGGCAAGATGCAGGTCCTCGCGAA
CCCGCGCAAGCTCGGCAGCATGTCGGGCTGGGGGCTCGAGGCGACGGGCTTCGTGCCGATGCCGGGCGGCGCGGCCTCCG
CGGCCTGA

Upstream 100 bases:

>100_bases
TCCGAGGCCTTGGCCGCCGCCCGGCGCCGCCGGATTTCCGAGGCAGCGGCGCGCGCGTGACGTAAAATAGCGCTTTTCTC
CCGTCTCCCCCTTTTCTGAT

Downstream 100 bases:

>100_bases
CCCGCCCGGCTCTCGCCTTTTGGCTGCCGCTCCTTATTCACGCTGAATCCAACCACGGAACGAACATGGAAATCGGACAA
TATCAACCGAATCTCGAAGG

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMARYGRGLICLTLTQERCKALNLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRAHTIATAVKRDARADEIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEVIKDDGSMARLPDLIAFSQEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGAFQAVLYRDKPTGSPHIALVR
GTPTPDRETPVRVHEPLSVLDLLETSSSTHSWTLDAAMKEIAERDLGAIVLLNCGDTKEHLVEVFRAFDEEEKAAVLKRR
PVDFKTFGIGAQILRDVGVGKMQVLANPRKLGSMSGWGLEATGFVPMPGGAASAA

Sequences:

>Translated_375_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMARYGRGLICLTLTQERCKALNLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRAHTIATAVKRDARADEIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEVIKDDGSMARLPDLIAFSQEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGAFQAVLYRDKPTGSPHIALVR
GTPTPDRETPVRVHEPLSVLDLLETSSSTHSWTLDAAMKEIAERDLGAIVLLNCGDTKEHLVEVFRAFDEEEKAAVLKRR
PVDFKTFGIGAQILRDVGVGKMQVLANPRKLGSMSGWGLEATGFVPMPGGAASAA
>Mature_374_residues
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMARYGRGLICLTLTQERCKALNLPLMTYRNGTQY
GTAFTVSIEAAEGVTTGISAADRAHTIATAVKRDARADEIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAV
ICEVIKDDGSMARLPDLIAFSQEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGAFQAVLYRDKPTGSPHIALVRG
TPTPDRETPVRVHEPLSVLDLLETSSSTHSWTLDAAMKEIAERDLGAIVLLNCGDTKEHLVEVFRAFDEEEKAAVLKRRP
VDFKTFGIGAQILRDVGVGKMQVLANPRKLGSMSGWGLEATGFVPMPGGAASAA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=196, Percent_Identity=51.0204081632653, Blast_Score=213, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=41.0891089108911, Blast_Score=159, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40263; Mature: 40131

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMARYGRGLICLTL
CCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKALNLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRAHTIATAVKRDARADE
CHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEVIKDDGSMARLPDLIA
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHCCHHHH
FSQEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGAFQAVLYRDKPTGSPHIALVR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEE
GTPTPDRETPVRVHEPLSVLDLLETSSSTHSWTLDAAMKEIAERDLGAIVLLNCGDTKEH
CCCCCCCCCCCEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCEEEEEECCCCHHH
LVEVFRAFDEEEKAAVLKRRPVDFKTFGIGAQILRDVGVGKMQVLANPRKLGSMSGWGLE
HHHHHHHHCCHHHHHHHHCCCCCEEEECCHHHHHHHCCCCEEEEECCCHHHCCCCCCCCC
ATGFVPMPGGAASAA
CCCEEECCCCCCCCC
>Mature Secondary Structure 
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVIAAEFVTPEAINFMARYGRGLICLTL
CCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKALNLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRAHTIATAVKRDARADE
CHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEVIKDDGSMARLPDLIA
HCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHCCHHHH
FSQEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGAFQAVLYRDKPTGSPHIALVR
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEEE
GTPTPDRETPVRVHEPLSVLDLLETSSSTHSWTLDAAMKEIAERDLGAIVLLNCGDTKEH
CCCCCCCCCCCEECCCHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCEEEEEECCCCHHH
LVEVFRAFDEEEKAAVLKRRPVDFKTFGIGAQILRDVGVGKMQVLANPRKLGSMSGWGLE
HHHHHHHHCCHHHHHHHHCCCCCEEEECCHHHHHHHCCCCEEEEECCCHHHCCCCCCCCC
ATGFVPMPGGAASAA
CCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]