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The map label for this gene is pucD [H]

Identifier: 238026366

GI number: 238026366

Start: 755642

End: 757996

Strand: Direct

Name: pucD [H]

Synonym: bglu_1g07000

Alternate gene names: 238026366

Gene position: 755642-757996 (Clockwise)

Preceding gene: 238026365

Following gene: 238026367

Centisome position: 19.34

GC content: 70.96

Gene sequence:

>2355_bases
ATGAACCAGCAAGCCGAACCGTTCCTGAATGACCTCGATTTCCGGCAGGTGCACGTCTCGCGTCCGCACGAATCCGCGCA
TCTGCACGTGAGCGGCCGCGCCAGCTACACCGACGACCTGCCGGTGCTCGCCGGCACGCTGCACGCCGCGCTCGGGCTGA
GCACGAGGGCCCATGCGCGCATCGTCTCGGCCGATCTCGACGCGGTGCGCGCCACGCCCGGCGTGGTGGCCGTGTTTACC
GCCGAGGACATCCCCGGCGTCAACGACTGCGGCCCGGTGATCCACGACGATCCGGTGCTGGCCGACGGCGTGGTGCAGTT
CGTCGGCCAGCCGGTGTTCATCGTGGTGGCCACCTCGCACGACGTCGCGCGGCTCGCCGCGCGCCGCGCGAAGATCGACT
ACGCGGAGCTGCCGGCGATCCTGACCGCGCAGGCCGCGCGCGCGGCCGAGTCCTACGTGCTGCCGCCGATGAAGCTCGCG
CGCGGCGACGCGGCCGGGCGCGCGGCGGCGGCCCCGCGGCGCGACGCGGGCGAGCTGACGCTGGGCGGCCAGGAGCAGTT
CTATCTCGAAGGGCAGGTGGCCTACGCGGTGCCGAAGGACGACGACGGCATGCACGTGTACTGCTCCACGCAGCACCCCA
GCGAGATGCAGCACGTGGTGGCGCACCTGCTCGGGGTGGCCTCGCACAACGTGCTGGTGGAATGCCGGCGCATGGGCGGC
GGCTTCGGCGGCAAGGAATCGCAGTCGGCCCTGTTCGCGTGCTGCGCGGCGCTCGCCGCCTGGAAGCTGCTGTGCCCGGT
GAAACTGCGCGCCGACCGTGACGACGACATGATCATCACCGGCAAGCGCCATGACTTCCATTACCGCTACGACGTGGGCT
ACGACGAAACCGGCGCGATCGACGGCGTGTCGGTGGAGATGACCTCGCGCTGCGGCTTCTCGGCCGACCTGTCGGGGCCA
GTCATGACGCGCGCGGTCTGTCACTTCGACAACGCCTACTGGCTGCCCGACGTCTCGATCGCCGGCTACTGCGGCAAGAC
CAACACCCAGTCGAACACCGCGTTTCGCGGCTTCGGCGGCCCGCAGGGCGCGTTCGCGATCGAGACCATCATCGACAACA
TCGCGCGCGATCTCGGCCTCGATCCGCTCGACGTGCGCTACCGCAACCTGTACGGCCGGGACGAGCGCAACGTCACGCCC
TACGGCCAGACCATCGAGGACAACGTGCTGCACGCGCTGCTCGGCGAGCTGGAGGCGACCAGCGGCTATCGCGCGCGGCG
CGCGGCCGTGCGCGAGTTCAACGCGCGCAGCCCGGTGCTGAAGAAGGGCATCGCGCTCACGCCGGTCAAGTTCGGCATCG
CGTTCAACGTCGCGCACCTGAACCAGGCCGGCGCGCTGGTGCATATCTATACCGACGGCTCGATCCTCGTGAACCACGGC
GGCACCGAGATGGGGCAGGGGCTCAACACCAAGGTCGCGCAGGTGGTCGCGCACGAACTCGGCGTCGGGTTCGGCCGCGT
GCGCGTGACGGCCACCGACACCAGCAAGGTCGCGAACACCTCGGCCACCGCCGCCTCCACCGGCTCGGACCTGAACGGCA
AGGCCGCGCAGGACGCCGCGCGCCAATTGCGCGAGCGGCTCGCCGCGTTCGCCGCCGAGCGGCTCGGCGAGCCCGACGCG
CCGGCCGTGGCCGCCGCCGAGGTGCGCTTCGCCAACGATCAGGTGTGGATCGGCGCGCGGGCCGTGCCGTTCGGCGAGGT
GGTCGCCCAGGCCTATCTGGCGCGCGTGCAGCTATGGTCGGACGGCTTCTACGCCACGCCGAAGCTGCACTGGAACCAGG
CGACGCTGCAGGGCCGGCCGTTTTTCTATTACGCCTACGGCGCGGCCTGCAGCGAGGTGGTGATCGATACCCTGACCGGC
GAGATGCGCGTGCTGCGCGCCGATGTGCTGCACGACGCGGGCGCCTCGCTGAACCCGGCGATCGATCGGGGCCAGGTGGA
GGGCGGCTTCATCCAGGGCATGGGCTGGCTCACCAGCGAGGAGCTGTGGTGGAACGACGGCGGCCGGCTGATGACGCACG
CGCCGTCCACCTACAAGATCCCGACCGTCAACGACACCCCGCCCGACTTCCGCGTCGAGCTGTTCCGCAATCGCAACGCC
GAGGACAGCATCCACCGCTCGAAGGCGGTCGGCGAGCCGCCGCTGCTGCTGGCGTTCTCGGTGTTCTTCGCGATCCGCGA
CGCGGTGGCGGCGGTCGGCGACTACCGCGTGCAGCCGCCGCTGCATGCGCCCGCCACCGGCGAGGCGATCCTGGGCGCGG
TGCAGGCCGTGCGTGCGGCCGCCGCGCGCAGCTGA

Upstream 100 bases:

>100_bases
GAGGCGCTGAACGTGCGCTGCGTGAGCGCCGAGGCGGCGGGGGCCGCCGGGCCCGCCGTCGCCGACCTTTGACCGAACCG
GAACACGAAAGACCCGCGCC

Downstream 100 bases:

>100_bases
GGCATCATGCTGCCGTCACCGCGCCGGGCCGGCCGGCTTCGCGACCCCGTGCACGCGTTCGCGCCGATGCACGTGGTGCT
GTTCGGCGCCGGCCACGTCG

Product: xanthine dehydrogenase, molybdopterin binding subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 784; Mature: 784

Protein sequence:

>784_residues
MNQQAEPFLNDLDFRQVHVSRPHESAHLHVSGRASYTDDLPVLAGTLHAALGLSTRAHARIVSADLDAVRATPGVVAVFT
AEDIPGVNDCGPVIHDDPVLADGVVQFVGQPVFIVVATSHDVARLAARRAKIDYAELPAILTAQAARAAESYVLPPMKLA
RGDAAGRAAAAPRRDAGELTLGGQEQFYLEGQVAYAVPKDDDGMHVYCSTQHPSEMQHVVAHLLGVASHNVLVECRRMGG
GFGGKESQSALFACCAALAAWKLLCPVKLRADRDDDMIITGKRHDFHYRYDVGYDETGAIDGVSVEMTSRCGFSADLSGP
VMTRAVCHFDNAYWLPDVSIAGYCGKTNTQSNTAFRGFGGPQGAFAIETIIDNIARDLGLDPLDVRYRNLYGRDERNVTP
YGQTIEDNVLHALLGELEATSGYRARRAAVREFNARSPVLKKGIALTPVKFGIAFNVAHLNQAGALVHIYTDGSILVNHG
GTEMGQGLNTKVAQVVAHELGVGFGRVRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAERLGEPDA
PAVAAAEVRFANDQVWIGARAVPFGEVVAQAYLARVQLWSDGFYATPKLHWNQATLQGRPFFYYAYGAACSEVVIDTLTG
EMRVLRADVLHDAGASLNPAIDRGQVEGGFIQGMGWLTSEELWWNDGGRLMTHAPSTYKIPTVNDTPPDFRVELFRNRNA
EDSIHRSKAVGEPPLLLAFSVFFAIRDAVAAVGDYRVQPPLHAPATGEAILGAVQAVRAAAARS

Sequences:

>Translated_784_residues
MNQQAEPFLNDLDFRQVHVSRPHESAHLHVSGRASYTDDLPVLAGTLHAALGLSTRAHARIVSADLDAVRATPGVVAVFT
AEDIPGVNDCGPVIHDDPVLADGVVQFVGQPVFIVVATSHDVARLAARRAKIDYAELPAILTAQAARAAESYVLPPMKLA
RGDAAGRAAAAPRRDAGELTLGGQEQFYLEGQVAYAVPKDDDGMHVYCSTQHPSEMQHVVAHLLGVASHNVLVECRRMGG
GFGGKESQSALFACCAALAAWKLLCPVKLRADRDDDMIITGKRHDFHYRYDVGYDETGAIDGVSVEMTSRCGFSADLSGP
VMTRAVCHFDNAYWLPDVSIAGYCGKTNTQSNTAFRGFGGPQGAFAIETIIDNIARDLGLDPLDVRYRNLYGRDERNVTP
YGQTIEDNVLHALLGELEATSGYRARRAAVREFNARSPVLKKGIALTPVKFGIAFNVAHLNQAGALVHIYTDGSILVNHG
GTEMGQGLNTKVAQVVAHELGVGFGRVRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAERLGEPDA
PAVAAAEVRFANDQVWIGARAVPFGEVVAQAYLARVQLWSDGFYATPKLHWNQATLQGRPFFYYAYGAACSEVVIDTLTG
EMRVLRADVLHDAGASLNPAIDRGQVEGGFIQGMGWLTSEELWWNDGGRLMTHAPSTYKIPTVNDTPPDFRVELFRNRNA
EDSIHRSKAVGEPPLLLAFSVFFAIRDAVAAVGDYRVQPPLHAPATGEAILGAVQAVRAAAARS
>Mature_784_residues
MNQQAEPFLNDLDFRQVHVSRPHESAHLHVSGRASYTDDLPVLAGTLHAALGLSTRAHARIVSADLDAVRATPGVVAVFT
AEDIPGVNDCGPVIHDDPVLADGVVQFVGQPVFIVVATSHDVARLAARRAKIDYAELPAILTAQAARAAESYVLPPMKLA
RGDAAGRAAAAPRRDAGELTLGGQEQFYLEGQVAYAVPKDDDGMHVYCSTQHPSEMQHVVAHLLGVASHNVLVECRRMGG
GFGGKESQSALFACCAALAAWKLLCPVKLRADRDDDMIITGKRHDFHYRYDVGYDETGAIDGVSVEMTSRCGFSADLSGP
VMTRAVCHFDNAYWLPDVSIAGYCGKTNTQSNTAFRGFGGPQGAFAIETIIDNIARDLGLDPLDVRYRNLYGRDERNVTP
YGQTIEDNVLHALLGELEATSGYRARRAAVREFNARSPVLKKGIALTPVKFGIAFNVAHLNQAGALVHIYTDGSILVNHG
GTEMGQGLNTKVAQVVAHELGVGFGRVRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAERLGEPDA
PAVAAAEVRFANDQVWIGARAVPFGEVVAQAYLARVQLWSDGFYATPKLHWNQATLQGRPFFYYAYGAACSEVVIDTLTG
EMRVLRADVLHDAGASLNPAIDRGQVEGGFIQGMGWLTSEELWWNDGGRLMTHAPSTYKIPTVNDTPPDFRVELFRNRNA
EDSIHRSKAVGEPPLLLAFSVFFAIRDAVAAVGDYRVQPPLHAPATGEAILGAVQAVRAAAARS

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=760, Percent_Identity=42.7631578947368, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI71773480, Length=746, Percent_Identity=39.142091152815, Blast_Score=476, Evalue=1e-134,
Organism=Escherichia coli, GI1789230, Length=750, Percent_Identity=29.3333333333333, Blast_Score=213, Evalue=5e-56,
Organism=Escherichia coli, GI1789246, Length=787, Percent_Identity=26.6836086404066, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1786478, Length=766, Percent_Identity=25.4569190600522, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=776, Percent_Identity=40.7216494845361, Blast_Score=516, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI32566215, Length=714, Percent_Identity=31.2324929971989, Blast_Score=324, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17539860, Length=725, Percent_Identity=31.448275862069, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI17737937, Length=774, Percent_Identity=41.6020671834625, Blast_Score=555, Evalue=1e-158,
Organism=Drosophila melanogaster, GI24647193, Length=766, Percent_Identity=31.9843342036554, Blast_Score=329, Evalue=4e-90,
Organism=Drosophila melanogaster, GI24647199, Length=763, Percent_Identity=31.1926605504587, Blast_Score=327, Evalue=3e-89,
Organism=Drosophila melanogaster, GI24647201, Length=763, Percent_Identity=31.1926605504587, Blast_Score=307, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24647195, Length=779, Percent_Identity=31.5789473684211, Blast_Score=306, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24647197, Length=779, Percent_Identity=31.5789473684211, Blast_Score=306, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 84120; Mature: 84120

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLNDLDFRQVHVSRPHESAHLHVSGRASYTDDLPVLAGTLHAALGLSTRAHAR
CCCCCCCHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHE
IVSADLDAVRATPGVVAVFTAEDIPGVNDCGPVIHDDPVLADGVVQFVGQPVFIVVATSH
EEECCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCC
DVARLAARRAKIDYAELPAILTAQAARAAESYVLPPMKLARGDAAGRAAAAPRRDAGELT
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEE
LGGQEQFYLEGQVAYAVPKDDDGMHVYCSTQHPSEMQHVVAHLLGVASHNVLVECRRMGG
ECCCCEEEEECEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCC
GFGGKESQSALFACCAALAAWKLLCPVKLRADRDDDMIITGKRHDFHYRYDVGYDETGAI
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCEEEEEECCCCCCCCC
DGVSVEMTSRCGFSADLSGPVMTRAVCHFDNAYWLPDVSIAGYCGKTNTQSNTAFRGFGG
CCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCEEECCCCCCCCCCCEEECCCC
PQGAFAIETIIDNIARDLGLDPLDVRYRNLYGRDERNVTPYGQTIEDNVLHALLGELEAT
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SGYRARRAAVREFNARSPVLKKGIALTPVKFGIAFNVAHLNQAGALVHIYTDGSILVNHG
CCHHHHHHHHHHCCCCCCHHHCCCEECEEEECEEEEEEEECCCCCEEEEEECCEEEEECC
GTEMGQGLNTKVAQVVAHELGVGFGRVRVTATDTSKVANTSATAASTGSDLNGKAAQDAA
CHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCCHHHHHHH
RQLRERLAAFAAERLGEPDAPAVAAAEVRFANDQVWIGARAVPFGEVVAQAYLARVQLWS
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHEEEC
DGFYATPKLHWNQATLQGRPFFYYAYGAACSEVVIDTLTGEMRVLRADVLHDAGASLNPA
CCEEECCEEECCCEEECCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
IDRGQVEGGFIQGMGWLTSEELWWNDGGRLMTHAPSTYKIPTVNDTPPDFRVELFRNRNA
CCCCCCCCCEEECCCCCCCCCEEECCCCEEEEECCCCEECCCCCCCCCCHHHHEECCCCC
EDSIHRSKAVGEPPLLLAFSVFFAIRDAVAAVGDYRVQPPLHAPATGEAILGAVQAVRAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AARS
HCCC
>Mature Secondary Structure
MNQQAEPFLNDLDFRQVHVSRPHESAHLHVSGRASYTDDLPVLAGTLHAALGLSTRAHAR
CCCCCCCHHCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHHE
IVSADLDAVRATPGVVAVFTAEDIPGVNDCGPVIHDDPVLADGVVQFVGQPVFIVVATSH
EEECCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCC
DVARLAARRAKIDYAELPAILTAQAARAAESYVLPPMKLARGDAAGRAAAAPRRDAGELT
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCCEE
LGGQEQFYLEGQVAYAVPKDDDGMHVYCSTQHPSEMQHVVAHLLGVASHNVLVECRRMGG
ECCCCEEEEECEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCC
GFGGKESQSALFACCAALAAWKLLCPVKLRADRDDDMIITGKRHDFHYRYDVGYDETGAI
CCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEECCCCCEEEEEECCCCCCCCC
DGVSVEMTSRCGFSADLSGPVMTRAVCHFDNAYWLPDVSIAGYCGKTNTQSNTAFRGFGG
CCEEEEECCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCEEECCCCCCCCCCCEEECCCC
PQGAFAIETIIDNIARDLGLDPLDVRYRNLYGRDERNVTPYGQTIEDNVLHALLGELEAT
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SGYRARRAAVREFNARSPVLKKGIALTPVKFGIAFNVAHLNQAGALVHIYTDGSILVNHG
CCHHHHHHHHHHCCCCCCHHHCCCEECEEEECEEEEEEEECCCCCEEEEEECCEEEEECC
GTEMGQGLNTKVAQVVAHELGVGFGRVRVTATDTSKVANTSATAASTGSDLNGKAAQDAA
CHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCCHHHHHHH
RQLRERLAAFAAERLGEPDAPAVAAAEVRFANDQVWIGARAVPFGEVVAQAYLARVQLWS
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHEEEC
DGFYATPKLHWNQATLQGRPFFYYAYGAACSEVVIDTLTGEMRVLRADVLHDAGASLNPA
CCEEECCEEECCCEEECCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
IDRGQVEGGFIQGMGWLTSEELWWNDGGRLMTHAPSTYKIPTVNDTPPDFRVELFRNRNA
CCCCCCCCCEEECCCCCCCCCEEECCCCEEEEECCCCEECCCCCCCCCCHHHHEECCCCC
EDSIHRSKAVGEPPLLLAFSVFFAIRDAVAAVGDYRVQPPLHAPATGEAILGAVQAVRAA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AARS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]