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The map label for this gene is ubiH [H]

Identifier: 238026251

GI number: 238026251

Start: 612861

End: 614066

Strand: Reverse

Name: ubiH [H]

Synonym: bglu_1g05840

Alternate gene names: 238026251

Gene position: 614066-612861 (Counterclockwise)

Preceding gene: 238026252

Following gene: 238026250

Centisome position: 15.72

GC content: 77.28

Gene sequence:

>1206_bases
ATGACCACCTCCGCTCCGCTTGCGCCCGCCGCCGCACCGTTCGACGCCGACCTCGCGATCATCGGCGCCGGCCCGGTCGG
GCTCGCGCTGGCCGGCTGGCTGGCGCGCCGCAGCGCGACCCGCGCGCTGTCGGTCGTGCTGGTCGATGCGCGCGAGCCGT
CGGCCAGCGCCGACGACCCGCGCGCGATCGCCGTCTCGCACGGCAGCCGGCTCCTGCTCGAGCCGCTCGGCTGGCCGGCC
GACGCGACGCCGATCGAACACATCCACGTCTCGCAGCGCGGCCACTTCGGCCGCACGCTGATCGACCGCGACGAACACGG
CGTGGCCGCGCTCGGCTACGTCGCGCGCTACGGCTCGCTGGTGGACGCGCTGGCACGCGCCGTGCGCGGCACGCCGGTGC
GCTGGATGACCTCGACCCAGGCGCGCGCGCCGCGCCAGGACGCCGGCGGCGTGAGCGTGACGCTCGCGGCGCCCGACGGC
GAACGCGAGCTGCGCGTGCGCGCGCTCGTCAACGCCGAGGGTGGGCTGTTCCAGGGCGGCACGGGCGACGCGCTCGATGG
CCGCCACCGCCGCGACTACGGGCAAACCGCGATCGTCGGCACCGTCAGCGCCGCCGCGCCGCGCCCGCGCACCGCCTGGG
AGCGTTTCACGCCCGAGGGGCCGCTCGCGCTGCTGCCGCTCGGCGGCGCGGGCCAGGCCGACTACGCGCTGGTCTGGTGC
TGCGCGCCCGACGAGGCCGCGCGGCGCGCGGCACTGCCCGACGCGGCGTTCCTGAGCGAGCTCGGCGCGGCCTTCGGCGA
GCGCATGGGGCGCTTCACGCGCGTCGTCGGCCGCGCCTCGTTCCCGCTCGGGCTGGTGGCCGCGCCGACGCTCGTCGAGG
GCCGCATCGCCACGGTCGGCAACGCGGCGCAGACGCTGCATCCGGTGGCGGGCCAGGGCCTGAACCTCGGGCTGCGCGAC
GCGCACACGCTGGCCGACGCGCTTTCCGAACACGGCGCGACGCCGCTCGCGCTGGCCGCCTTCAACCTGCGCCGCGCGCT
CGACCGGCGCCTCACGATCGGCGCGACCGATATGCTCGCGCGCCTGTTTACGATCGACTCGCGCCCGCTCGCGGCGCTGC
GCGGCGCGGCGCTGAGCGCGCTCGAATTCGTGCCGCCGCTGAAGACGGCGATCGCGCGCCAGATGATGTTCGGCCGGCGC
GGCTGA

Upstream 100 bases:

>100_bases
CACGGCACCTCGGGCCCGTCCGGCACTACGCCGCCGGCGCGGCCGTGACCGGCGCGCCGGCGTGCCGCCTCCCCCGAACC
CGCTCCCCCGCTTTCGCCCG

Downstream 100 bases:

>100_bases
GCGGCAGCACCGCGCCGCCCGGCCGCCCGCCCAGGCGCCTGTCACCGGACCGTCACGCAAGCTTCACGGCGATTCGATGC
GGTTCGGCGCTTCGCCATGC

Product: hypothetical protein

Products: H2O; 2-octaprenyl-6-methoxy-1,4-benzoquinone [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTTSAPLAPAAAPFDADLAIIGAGPVGLALAGWLARRSATRALSVVLVDAREPSASADDPRAIAVSHGSRLLLEPLGWPA
DATPIEHIHVSQRGHFGRTLIDRDEHGVAALGYVARYGSLVDALARAVRGTPVRWMTSTQARAPRQDAGGVSVTLAAPDG
ERELRVRALVNAEGGLFQGGTGDALDGRHRRDYGQTAIVGTVSAAAPRPRTAWERFTPEGPLALLPLGGAGQADYALVWC
CAPDEAARRAALPDAAFLSELGAAFGERMGRFTRVVGRASFPLGLVAAPTLVEGRIATVGNAAQTLHPVAGQGLNLGLRD
AHTLADALSEHGATPLALAAFNLRRALDRRLTIGATDMLARLFTIDSRPLAALRGAALSALEFVPPLKTAIARQMMFGRR
G

Sequences:

>Translated_401_residues
MTTSAPLAPAAAPFDADLAIIGAGPVGLALAGWLARRSATRALSVVLVDAREPSASADDPRAIAVSHGSRLLLEPLGWPA
DATPIEHIHVSQRGHFGRTLIDRDEHGVAALGYVARYGSLVDALARAVRGTPVRWMTSTQARAPRQDAGGVSVTLAAPDG
ERELRVRALVNAEGGLFQGGTGDALDGRHRRDYGQTAIVGTVSAAAPRPRTAWERFTPEGPLALLPLGGAGQADYALVWC
CAPDEAARRAALPDAAFLSELGAAFGERMGRFTRVVGRASFPLGLVAAPTLVEGRIATVGNAAQTLHPVAGQGLNLGLRD
AHTLADALSEHGATPLALAAFNLRRALDRRLTIGATDMLARLFTIDSRPLAALRGAALSALEFVPPLKTAIARQMMFGRR
G
>Mature_400_residues
TTSAPLAPAAAPFDADLAIIGAGPVGLALAGWLARRSATRALSVVLVDAREPSASADDPRAIAVSHGSRLLLEPLGWPAD
ATPIEHIHVSQRGHFGRTLIDRDEHGVAALGYVARYGSLVDALARAVRGTPVRWMTSTQARAPRQDAGGVSVTLAAPDGE
RELRVRALVNAEGGLFQGGTGDALDGRHRRDYGQTAIVGTVSAAAPRPRTAWERFTPEGPLALLPLGGAGQADYALVWCC
APDEAARRAALPDAAFLSELGAAFGERMGRFTRVVGRASFPLGLVAAPTLVEGRIATVGNAAQTLHPVAGQGLNLGLRDA
HTLADALSEHGATPLALAAFNLRRALDRRLTIGATDMLARLFTIDSRPLAALRGAALSALEFVPPLKTAIARQMMFGRRG

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=343, Percent_Identity=27.6967930029155, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI32967307, Length=343, Percent_Identity=27.6967930029155, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1789274, Length=391, Percent_Identity=34.0153452685422, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786883, Length=390, Percent_Identity=29.4871794871795, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1789273, Length=396, Percent_Identity=28.7878787878788, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321694, Length=466, Percent_Identity=25.7510729613734, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920760, Length=429, Percent_Identity=25.4079254079254, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 41860; Mature: 41729

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSAPLAPAAAPFDADLAIIGAGPVGLALAGWLARRSATRALSVVLVDAREPSASADDP
CCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCC
RAIAVSHGSRLLLEPLGWPADATPIEHIHVSQRGHFGRTLIDRDEHGVAALGYVARYGSL
CEEEEECCCEEEEECCCCCCCCCCHHEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
VDALARAVRGTPVRWMTSTQARAPRQDAGGVSVTLAAPDGERELRVRALVNAEGGLFQGG
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCEEECC
TGDALDGRHRRDYGQTAIVGTVSAAAPRPRTAWERFTPEGPLALLPLGGAGQADYALVWC
CCCCCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCEEEEEE
CAPDEAARRAALPDAAFLSELGAAFGERMGRFTRVVGRASFPLGLVAAPTLVEGRIATVG
ECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHCCCEEECC
NAAQTLHPVAGQGLNLGLRDAHTLADALSEHGATPLALAAFNLRRALDRRLTIGATDMLA
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCEECCHHHHHH
RLFTIDSRPLAALRGAALSALEFVPPLKTAIARQMMFGRRG
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTSAPLAPAAAPFDADLAIIGAGPVGLALAGWLARRSATRALSVVLVDAREPSASADDP
CCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCC
RAIAVSHGSRLLLEPLGWPADATPIEHIHVSQRGHFGRTLIDRDEHGVAALGYVARYGSL
CEEEEECCCEEEEECCCCCCCCCCHHEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHHH
VDALARAVRGTPVRWMTSTQARAPRQDAGGVSVTLAAPDGERELRVRALVNAEGGLFQGG
HHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCEEECC
TGDALDGRHRRDYGQTAIVGTVSAAAPRPRTAWERFTPEGPLALLPLGGAGQADYALVWC
CCCCCCCCHHHCCCCEEEEEEECCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCEEEEEE
CAPDEAARRAALPDAAFLSELGAAFGERMGRFTRVVGRASFPLGLVAAPTLVEGRIATVG
ECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHCCCEEECC
NAAQTLHPVAGQGLNLGLRDAHTLADALSEHGATPLALAAFNLRRALDRRLTIGATDMLA
CHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCEECCHHHHHH
RLFTIDSRPLAALRGAALSALEFVPPLKTAIARQMMFGRRG
HHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-octaprenyl-6-methoxyphenol; O2 [C]

Specific reaction: 2-octaprenyl-6-methoxyphenol + O2 = H2O + 2-octaprenyl-6-methoxy-1,4-benzoquinone [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]