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The map label for this gene is ung [H]

Identifier: 238026105

GI number: 238026105

Start: 452374

End: 453222

Strand: Reverse

Name: ung [H]

Synonym: bglu_1g04340

Alternate gene names: 238026105

Gene position: 453222-452374 (Counterclockwise)

Preceding gene: 238026106

Following gene: 238026100

Centisome position: 11.6

GC content: 71.38

Gene sequence:

>849_bases
ATGGCTAACCGCCCCTCTTCCCGCAAGGCGCCGACGGCCCAGGCCTCGCTGTTCGACGCGCCTGCCGCAGCGGTGGCGCC
GCCCGCCGCTGACAAGATCGCGCTGCACGCCGGCGCCGGCCCGGTGCCGCCGCTGCCGCTCGCCGCGCAGTTCGACGCGC
TGCCCGCCGCATGGCGCGCGTTGCTGGCGCCGTTCACCGCGAGCGATACCTACGCGCCGCTGTGCCGCTTCGTCGATGCC
GAGCGCGCCGCCGGCAAGACGATCTATCCAGCCGACGTGTTCCGCGCGCTGCGCCTGACCGCGCCTGACGACGTGAAGGT
CGTGATCCTCGGCCAGGATCCCTACCACGGCGACGATCACGGCACACCGCAGGCGCACGGCCTTGCGTTCTCGGTGCCGC
CCGCGGTACGACCGCCGCCGTCGCTGCGCAATATCTTCAAGGAAATCACGGCCAATTTCGGCTACGCCACGCCGCGGCAC
GGCTGCCTCGATTCGTGGGCGCGCCAGGGCGTGCTGCTGCTCAATACCGTGCTGACCGTGGAGCGAGGCGCGGCGGCGAG
CCACGCGAAACACGGCTGGGAGCCCTGCACCGATACGCTGATCCGCGAGCTCGCGCGGCGCCATCGCGGACTCGTGTTCA
TGCTGTGGGGCGCGCATGCGCAGGCCAAGCGCGCGCTGTTCGACGCCAGCGTGCATTGCGTGCTCGAATCGCCGCATCCG
TCGCCGCTGTCGGCGCACCGCGGCTTTCTCGGCAACCGCCACTTCGCGCTCGCCAACGCATACCTGAGCGAGCACGGTCA
AGCACCGATCGACTGGCGCCTGCCCGACGAGGCGCAGGTGCTGGCCTGA

Upstream 100 bases:

>100_bases
CGGCGGAACTCGGCCGCGCGCTGCCGGGCCTCGCGCCCGAGGATCGCAGCAAGGCGCAGCGCGGCTACCAGCTGCGCGCC
GCCTGAGGCCCGCGCCGCGC

Downstream 100 bases:

>100_bases
GCGCCGTGCTCGAGCCGCGCCTGGCGCGTCCGGCGGCTGCGCCGCCCCTCCCCCGCCCCTGATGCAAACAGCCCGATCGG
CTAGGGCCGATCGGGCTGTT

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MANRPSSRKAPTAQASLFDAPAAAVAPPAADKIALHAGAGPVPPLPLAAQFDALPAAWRALLAPFTASDTYAPLCRFVDA
ERAAGKTIYPADVFRALRLTAPDDVKVVILGQDPYHGDDHGTPQAHGLAFSVPPAVRPPPSLRNIFKEITANFGYATPRH
GCLDSWARQGVLLLNTVLTVERGAAASHAKHGWEPCTDTLIRELARRHRGLVFMLWGAHAQAKRALFDASVHCVLESPHP
SPLSAHRGFLGNRHFALANAYLSEHGQAPIDWRLPDEAQVLA

Sequences:

>Translated_282_residues
MANRPSSRKAPTAQASLFDAPAAAVAPPAADKIALHAGAGPVPPLPLAAQFDALPAAWRALLAPFTASDTYAPLCRFVDA
ERAAGKTIYPADVFRALRLTAPDDVKVVILGQDPYHGDDHGTPQAHGLAFSVPPAVRPPPSLRNIFKEITANFGYATPRH
GCLDSWARQGVLLLNTVLTVERGAAASHAKHGWEPCTDTLIRELARRHRGLVFMLWGAHAQAKRALFDASVHCVLESPHP
SPLSAHRGFLGNRHFALANAYLSEHGQAPIDWRLPDEAQVLA
>Mature_281_residues
ANRPSSRKAPTAQASLFDAPAAAVAPPAADKIALHAGAGPVPPLPLAAQFDALPAAWRALLAPFTASDTYAPLCRFVDAE
RAAGKTIYPADVFRALRLTAPDDVKVVILGQDPYHGDDHGTPQAHGLAFSVPPAVRPPPSLRNIFKEITANFGYATPRHG
CLDSWARQGVLLLNTVLTVERGAAASHAKHGWEPCTDTLIRELARRHRGLVFMLWGAHAQAKRALFDASVHCVLESPHPS
PLSAHRGFLGNRHFALANAYLSEHGQAPIDWRLPDEAQVLA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=220, Percent_Identity=47.2727272727273, Blast_Score=194, Evalue=8e-50,
Organism=Homo sapiens, GI6224979, Length=220, Percent_Identity=47.2727272727273, Blast_Score=193, Evalue=1e-49,
Organism=Escherichia coli, GI1788934, Length=228, Percent_Identity=53.5087719298246, Blast_Score=232, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17556304, Length=273, Percent_Identity=38.0952380952381, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323620, Length=247, Percent_Identity=40.080971659919, Blast_Score=159, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 30235; Mature: 30103

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRPSSRKAPTAQASLFDAPAAAVAPPAADKIALHAGAGPVPPLPLAAQFDALPAAWRA
CCCCCCCCCCCCHHHHHHCCCCHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
LLAPFTASDTYAPLCRFVDAERAAGKTIYPADVFRALRLTAPDDVKVVILGQDPYHGDDH
HHCCCCCCCCHHHHHHHHHHHHHCCCEECHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
GTPQAHGLAFSVPPAVRPPPSLRNIFKEITANFGYATPRHGCLDSWARQGVLLLNTVLTV
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEHHHHHHH
ERGAAASHAKHGWEPCTDTLIRELARRHRGLVFMLWGAHAQAKRALFDASVHCVLESPHP
HCCCCHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCEEEEEEECCCC
SPLSAHRGFLGNRHFALANAYLSEHGQAPIDWRLPDEAQVLA
CCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
ANRPSSRKAPTAQASLFDAPAAAVAPPAADKIALHAGAGPVPPLPLAAQFDALPAAWRA
CCCCCCCCCCCHHHHHHCCCCHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
LLAPFTASDTYAPLCRFVDAERAAGKTIYPADVFRALRLTAPDDVKVVILGQDPYHGDDH
HHCCCCCCCCHHHHHHHHHHHHHCCCEECHHHHHHHHHCCCCCCEEEEEECCCCCCCCCC
GTPQAHGLAFSVPPAVRPPPSLRNIFKEITANFGYATPRHGCLDSWARQGVLLLNTVLTV
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEHHHHHHH
ERGAAASHAKHGWEPCTDTLIRELARRHRGLVFMLWGAHAQAKRALFDASVHCVLESPHP
HCCCCHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCEEEEEEECCCC
SPLSAHRGFLGNRHFALANAYLSEHGQAPIDWRLPDEAQVLA
CCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA