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The map label for this gene is murA [H]

Identifier: 238026003

GI number: 238026003

Start: 348425

End: 349771

Strand: Direct

Name: murA [H]

Synonym: bglu_1g03290

Alternate gene names: 238026003

Gene position: 348425-349771 (Clockwise)

Preceding gene: 238026002

Following gene: 238026004

Centisome position: 8.92

GC content: 70.9

Gene sequence:

>1347_bases
GTGCAAGTTTCAGTCAACGAACGCGACGCGGTAAGCCACGTCGCGACGGCGAACCCGTCCGCCGGCCGGGTTTCGCAAGG
ACAGCCGGAGCGGCTCGTGATCACCGGCGGCAGGCGGCTTTCCGGCGAGATCCGGGTGTCGGGCGCGAAGAACGCGGCGC
TGCCGATTCTCTGCGCGGGCCTGCTCAGCGCCGAGCCGCTGCGGCTCGACAACGTGCCCGACCTGCAGGACGTGCGCACC
ATGCTCGCGCTGCTGGGCGGGATGGGCGTGAAGAGCGCGGTGGACGGCGCGCGCGTCACGCTCGACGCGGCCAGCGTGAC
CGATCCGGTGGCGCCTTACGAGCTGGTCAAGACCATGCGCGCGTCGATTCTCGTGCTTGGCCCGCTGCTGGCGCGCTTCG
GCTACGCGAAGGTATCGCTGCCGGGCGGCTGCGCGATCGGCGCGCGGCCGGTGGATCAGCACATCAAGGGGCTGCAGGCG
ATGGGCGCCGAGATCACCATCGAGCACGGCTACATCGAGGCGCGCGCCACGCGCCTGAAGGGCGCGCGCCTCGTCACCGA
CATGATCACGGTGACCGGCACCGAGAACCTGCTGATGGCCGCCACGCTCGCCGACGGCGAGACCGTGATCGAGAACGCCG
CGCGCGAGCCCGAGGTGACCGACCTCGCCAACCTGCTGGTGGCGATGGGGGCGAGGATCGACGGGATCGGCACCGACCGG
CTCGTGATCCAGGGCGTCGAGCGGCTGCACGGCGCGAGCCACGCGGTCGTGCCCGACCGCATCGAGGCCGGCACCTTCCT
TTGCGCGGCGGCGGCCGCGGGCGGTGAGCTCACGCTGCGCGGCATGCGCGCGAACCTGCTCGACGCGGTGCTCGGCAAGC
TGCGCGAGACCGGCGCCAAGCTCGACGAGCGCGACGACGCGCTGCGCGTGACGATGGACCGGCGCCCGGCCGCGGTGGCG
ATCCGCACCTCCGAATATCCGGCCTTCCCGACCGACATGCAGGCGCAGTTCATGACCCTGAACGCGGTGGCCGCCGGCAC
CGCGCACGTCGTCGAGACCATCTTCGAGAACCGCTTCATGCACGTGCAGGAGCTGAACCGGCTCGGTGCCGACATCGTGG
TGGACGGCAACACGGCGCTCGTCACCGGCGTGACGCAGCTCTCGGGCGCACGCGTGATGGCCACCGACCTGCGCGCCTCG
GCGAGCCTCGTGATCGCGGGGCTGTGCGCTGACGGCGAGACCGTCATCGACCGCATCTACCATCTCGATCGCGGCTATGA
TCGGATGGAGACCAAGCTGAACGCAGTTGGCGCCGACGTGCGCCGCATCACCGGGAGTGCCGCATGA

Upstream 100 bases:

>100_bases
GCGGCGCTCGGCGACCGCATGAAGCAGGAAATCCACGCGCTCAGCATGAAAACGCTGACGCCCGCCGAATGGCAGAACGC
ATAAAGAACGGACATCCTTC

Downstream 100 bases:

>100_bases
CCGCACCGCTGACCCTCGCGCTGTCGAAAGGGCGTATCTTCGAGGAAACCGTGCCGCTGCTCGCGGCCGCCGGCATCGAG
GTGGCGGGGGACCCCGAATC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MQVSVNERDAVSHVATANPSAGRVSQGQPERLVITGGRRLSGEIRVSGAKNAALPILCAGLLSAEPLRLDNVPDLQDVRT
MLALLGGMGVKSAVDGARVTLDAASVTDPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQA
MGAEITIEHGYIEARATRLKGARLVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLANLLVAMGARIDGIGTDR
LVIQGVERLHGASHAVVPDRIEAGTFLCAAAAAGGELTLRGMRANLLDAVLGKLRETGAKLDERDDALRVTMDRRPAAVA
IRTSEYPAFPTDMQAQFMTLNAVAAGTAHVVETIFENRFMHVQELNRLGADIVVDGNTALVTGVTQLSGARVMATDLRAS
ASLVIAGLCADGETVIDRIYHLDRGYDRMETKLNAVGADVRRITGSAA

Sequences:

>Translated_448_residues
MQVSVNERDAVSHVATANPSAGRVSQGQPERLVITGGRRLSGEIRVSGAKNAALPILCAGLLSAEPLRLDNVPDLQDVRT
MLALLGGMGVKSAVDGARVTLDAASVTDPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQA
MGAEITIEHGYIEARATRLKGARLVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLANLLVAMGARIDGIGTDR
LVIQGVERLHGASHAVVPDRIEAGTFLCAAAAAGGELTLRGMRANLLDAVLGKLRETGAKLDERDDALRVTMDRRPAAVA
IRTSEYPAFPTDMQAQFMTLNAVAAGTAHVVETIFENRFMHVQELNRLGADIVVDGNTALVTGVTQLSGARVMATDLRAS
ASLVIAGLCADGETVIDRIYHLDRGYDRMETKLNAVGADVRRITGSAA
>Mature_448_residues
MQVSVNERDAVSHVATANPSAGRVSQGQPERLVITGGRRLSGEIRVSGAKNAALPILCAGLLSAEPLRLDNVPDLQDVRT
MLALLGGMGVKSAVDGARVTLDAASVTDPVAPYELVKTMRASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQA
MGAEITIEHGYIEARATRLKGARLVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLANLLVAMGARIDGIGTDR
LVIQGVERLHGASHAVVPDRIEAGTFLCAAAAAGGELTLRGMRANLLDAVLGKLRETGAKLDERDDALRVTMDRRPAAVA
IRTSEYPAFPTDMQAQFMTLNAVAAGTAHVVETIFENRFMHVQELNRLGADIVVDGNTALVTGVTQLSGARVMATDLRAS
ASLVIAGLCADGETVIDRIYHLDRGYDRMETKLNAVGADVRRITGSAA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=56.3245823389022, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47119; Mature: 47119

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSVNERDAVSHVATANPSAGRVSQGQPERLVITGGRRLSGEIRVSGAKNAALPILCAG
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEECCEEEEECCCCCCHHHHHHH
LLSAEPLRLDNVPDLQDVRTMLALLGGMGVKSAVDGARVTLDAASVTDPVAPYELVKTMR
HHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
ASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQAMGAEITIEHGYIEARATRLK
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCEEEEHHHHHC
GARLVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLANLLVAMGARIDGIGTDR
CHHEEEHHEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCH
LVIQGVERLHGASHAVVPDRIEAGTFLCAAAAAGGELTLRGMRANLLDAVLGKLRETGAK
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCC
LDERDDALRVTMDRRPAAVAIRTSEYPAFPTDMQAQFMTLNAVAAGTAHVVETIFENRFM
CCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHEEEEEHHHCCHHHHHHHHHHHCCH
HVQELNRLGADIVVDGNTALVTGVTQLSGARVMATDLRASASLVIAGLCADGETVIDRIY
HHHHHHHCCCEEEECCCEEEEEEHHHHCCCEEEEEHHHCCCEEEEEEECCCCHHHHHHHH
HLDRGYDRMETKLNAVGADVRRITGSAA
HHCCCHHHHHHHHHHHCHHHHHHCCCCC
>Mature Secondary Structure
MQVSVNERDAVSHVATANPSAGRVSQGQPERLVITGGRRLSGEIRVSGAKNAALPILCAG
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEECCEEEEECCCCCCHHHHHHH
LLSAEPLRLDNVPDLQDVRTMLALLGGMGVKSAVDGARVTLDAASVTDPVAPYELVKTMR
HHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
ASILVLGPLLARFGYAKVSLPGGCAIGARPVDQHIKGLQAMGAEITIEHGYIEARATRLK
HHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCEEEEHHHHHC
GARLVTDMITVTGTENLLMAATLADGETVIENAAREPEVTDLANLLVAMGARIDGIGTDR
CHHEEEHHEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCH
LVIQGVERLHGASHAVVPDRIEAGTFLCAAAAAGGELTLRGMRANLLDAVLGKLRETGAK
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCC
LDERDDALRVTMDRRPAAVAIRTSEYPAFPTDMQAQFMTLNAVAAGTAHVVETIFENRFM
CCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHEEEEEHHHCCHHHHHHHHHHHCCH
HVQELNRLGADIVVDGNTALVTGVTQLSGARVMATDLRASASLVIAGLCADGETVIDRIY
HHHHHHHCCCEEEECCCEEEEEEHHHHCCCEEEEEHHHCCCEEEEEEECCCCHHHHHHHH
HLDRGYDRMETKLNAVGADVRRITGSAA
HHCCCHHHHHHHHHHHCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA