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The map label for this gene is hpd [H]

Identifier: 238025906

GI number: 238025906

Start: 246854

End: 247951

Strand: Reverse

Name: hpd [H]

Synonym: bglu_1g02320

Alternate gene names: 238025906

Gene position: 247951-246854 (Counterclockwise)

Preceding gene: 238025908

Following gene: 238025904

Centisome position: 6.35

GC content: 64.66

Gene sequence:

>1098_bases
ATGCAGATTCCCACCTGGGACAACCCCGTCGGCACCGACGGCTTCGAATTCATCGAATACACGGCGCCGGATCCGAAGGC
GCTCGGCCAGCTGTTCGAGCGGATGGGCTTCACCGCGATCGCGCGGCACCGGCACAAGGACGTCACGCTGTACCGCCAGG
GCGAGATCAACTTCCTCATCAACGCCGAACCGGATTCGTTCGCGCAGCGCTTCGCGCGGCTGCACGGCCCGTCGATCTGC
GCCATCGCGTTTCGCGTGCGCGACGCCGCGCTGGCCTACCGGCACGCGCTCGAACAGGGAGCCTGGGGCTTCGACAACAA
GACCGGGCCGATGGAACTGAATATTCCGGCGATCAAGGGCGTCGGCGATTCGCTGATCTATTTCGTCGACCGCTGGCGCG
GCAAGCATGGCGCAGCGCCGGGCAGCATCGGCGACATCGGCATCTACGACGTCGATTTCGAGCCGATCCCGGGCGCGGAC
CCGGCACCCGTCGGCCACGGCCTCACCTATATCGATCACCTCACGCACAACGTGCATCGCGGCCGGATGCGCGAATGGGC
CGAGTTCTACGAGCGCCTGTTCAACTTCCGCGAAGTGCGCTACTTCGACATCGAGGGCAAGGTGACGGGCGTGAAGTCGA
AGGCGATGACGTCGCCGTGCGGCAAGATCCGCATCCCGATCAATGAAGAGGGTTCGGACACGCCGGGCCAGATCCAGGAG
TATCTCGATGCGTACCGCGGCGAGGGCATCCAGCACATCGCGCTCGGTACCGAGAACATCTACGCCACGGTGGACGGCCT
GCGCGGCAAGGCGGTCACGCTGCTCGACACGATCGACACCTACTACGAACTCGTCGACCGCCGCGTCCCGAACCACGGCG
AGCCGCTCGACGAACTCCGCAAGCGCAAGATCCTGATCGACGGCGCCCACGACGACCTGCTGCTGCAGATCTTCACCGAG
AACCAGATCGGCCCGATCTTCTTCGAGATCATCCAGCGCAAGGGCAACCAGGGCTTCGGCGAGGGCAACTTCAAGGCCTT
GTTCGAATCGATCGAGCTGGACCAGATCCGCCGCGGCGTGGTGCAGGACAAGGCCTGA

Upstream 100 bases:

>100_bases
CGCAAGGAATTGCCGGTGCCGCGCGCCTACACTGTTTCGCATGCGGCACCCTGCCGCCCCCAACGACCGGCGACGCGAGC
CAATACCGGAGACGAGCACC

Downstream 100 bases:

>100_bases
TCGCGAGGCGCCCGCTGCCCGACTGCCGTGCCCCATCGAAGAAAAAGGCGAAAATCGCAGGATTTTCGCCTCTCTTTTGC
AGGTATCGGCCAGCCGGCGC

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: NA

Alternate protein names: 4HPPD; HPD; HPPDase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MQIPTWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTLYRQGEINFLINAEPDSFAQRFARLHGPSIC
AIAFRVRDAALAYRHALEQGAWGFDNKTGPMELNIPAIKGVGDSLIYFVDRWRGKHGAAPGSIGDIGIYDVDFEPIPGAD
PAPVGHGLTYIDHLTHNVHRGRMREWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTPGQIQE
YLDAYRGEGIQHIALGTENIYATVDGLRGKAVTLLDTIDTYYELVDRRVPNHGEPLDELRKRKILIDGAHDDLLLQIFTE
NQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGVVQDKA

Sequences:

>Translated_365_residues
MQIPTWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTLYRQGEINFLINAEPDSFAQRFARLHGPSIC
AIAFRVRDAALAYRHALEQGAWGFDNKTGPMELNIPAIKGVGDSLIYFVDRWRGKHGAAPGSIGDIGIYDVDFEPIPGAD
PAPVGHGLTYIDHLTHNVHRGRMREWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTPGQIQE
YLDAYRGEGIQHIALGTENIYATVDGLRGKAVTLLDTIDTYYELVDRRVPNHGEPLDELRKRKILIDGAHDDLLLQIFTE
NQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGVVQDKA
>Mature_365_residues
MQIPTWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTLYRQGEINFLINAEPDSFAQRFARLHGPSIC
AIAFRVRDAALAYRHALEQGAWGFDNKTGPMELNIPAIKGVGDSLIYFVDRWRGKHGAAPGSIGDIGIYDVDFEPIPGAD
PAPVGHGLTYIDHLTHNVHRGRMREWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTPGQIQE
YLDAYRGEGIQHIALGTENIYATVDGLRGKAVTLLDTIDTYYELVDRRVPNHGEPLDELRKRKILIDGAHDDLLLQIFTE
NQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGVVQDKA

Specific function: Unknown

COG id: COG3185

COG function: function code ER; 4-hydroxyphenylpyruvate dioxygenase and related hemolysins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI4504477, Length=354, Percent_Identity=28.8135593220339, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI285002264, Length=348, Percent_Identity=28.448275862069, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI14249394, Length=379, Percent_Identity=24.5382585751979, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555220, Length=205, Percent_Identity=38.0487804878049, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17550752, Length=223, Percent_Identity=30.4932735426009, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24667510, Length=309, Percent_Identity=32.0388349514563, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356105, Length=309, Percent_Identity=32.0388349514563, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.27 [H]

Molecular weight: Translated: 41145; Mature: 41145

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIPTWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTLYRQGEINFLI
CCCCCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCEEEEEECCEEEEE
NAEPDSFAQRFARLHGPSICAIAFRVRDAALAYRHALEQGAWGFDNKTGPMELNIPAIKG
ECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHCC
VGDSLIYFVDRWRGKHGAAPGSIGDIGIYDVDFEPIPGADPAPVGHGLTYIDHLTHNVHR
CCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GRMREWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTPGQIQE
HHHHHHHHHHHHHHCHHHEEEEEECCEEECCCHHHHCCCCCEEEEECCCCCCCCHHHHHH
YLDAYRGEGIQHIALGTENIYATVDGLRGKAVTLLDTIDTYYELVDRRVPNHGEPLDELR
HHHHHHCCCEEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHH
KRKILIDGAHDDLLLQIFTENQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGV
HCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHH
VQDKA
HCCCC
>Mature Secondary Structure
MQIPTWDNPVGTDGFEFIEYTAPDPKALGQLFERMGFTAIARHRHKDVTLYRQGEINFLI
CCCCCCCCCCCCCCHHEEEECCCCHHHHHHHHHHHCHHHHHHHCCCCEEEEEECCEEEEE
NAEPDSFAQRFARLHGPSICAIAFRVRDAALAYRHALEQGAWGFDNKTGPMELNIPAIKG
ECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHCC
VGDSLIYFVDRWRGKHGAAPGSIGDIGIYDVDFEPIPGADPAPVGHGLTYIDHLTHNVHR
CCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
GRMREWAEFYERLFNFREVRYFDIEGKVTGVKSKAMTSPCGKIRIPINEEGSDTPGQIQE
HHHHHHHHHHHHHHCHHHEEEEEECCEEECCCHHHHCCCCCEEEEECCCCCCCCHHHHHH
YLDAYRGEGIQHIALGTENIYATVDGLRGKAVTLLDTIDTYYELVDRRVPNHGEPLDELR
HHHHHHCCCEEEEEECCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHH
KRKILIDGAHDDLLLQIFTENQIGPIFFEIIQRKGNQGFGEGNFKALFESIELDQIRRGV
HCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCHHHHHHHH
VQDKA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]