Click here to switch to the map view.

The map label for this gene is fabH [H]

Identifier: 238025840

GI number: 238025840

Start: 172618

End: 173649

Strand: Reverse

Name: fabH [H]

Synonym: bglu_1g01660

Alternate gene names: 238025840

Gene position: 173649-172618 (Counterclockwise)

Preceding gene: 238025841

Following gene: 238025839

Centisome position: 4.45

GC content: 68.51

Gene sequence:

>1032_bases
ATGGCCGCACGCGCCACGATCCTCGACATCGCGAGCCACCTGCCCGCCATGGTGCTCGGCAACGACGCGCTCGCGGCGCT
GTACCCGGAGTGGCCGGCCGAGAAGATCCTCGCCAAGACCGGGATACGCGAGCGACGCGTGGCGGCCGACGACGAGACCG
CCTCGGACCTCGCGTTCGAGGCCGCGCGGCGGCTGTTCGCTCAGGGCAGCGTGCGCGCCGACGAGATCGATTTCGTGATC
CTCTGCACCCAGGCTCCCGACTACGTGCTGCCGGCCTCCGCCTGCGTGCTGCAGCACCGGCTCGGGATTCCGACCCACGC
CGGCGCGTTCGACGTGAATCTCGGCTGCTCGGGCTATGTGTACGGGCTGTCGCTCGCCAAAGGGCTGATCGAGACGGGTG
CGGCGCGCTGTGTGCTGCTGCTGACTGCCGATACCTATTCGAAGTACCTGCACCCGCTCGACAAGAGCGTGCGCACGCTG
TTCGGCGACGGCGCGACGGCCACCGCGATCGGCTTGGACGAGCGAGCGGCCGACGCCGAGGCCGAGCACATCGGCCCGTT
CGTGTTTGGCACCGACGGGCGCGGCGCGCAGAACCTGATCGTGCGCGCCGGGCTATTCCGCGAGCCGCGCAGCGCCAAGA
GCGCTCGCGAGCACGAGGATGCCTCCGGCAACGTGCGCACCGACGAGCATCTCTACATGAACGGCGCCGAGGTGATGGCG
TTCTCGCTCGCAGAGGTGCCGCGCGCGGCTGACCGGCTGCTCGAACGCGCTTGCCTCACGCGCGACGACATCGACTGCTT
CGTGCTGCACCAGGCGAACCGGTTTATGCTCGAGGCGCTGCGCAAGAAAATGAAAGTTCCCGAGGATCGCTTCCCGATCC
TCATGGAGTACACCGGCAACACGGTATCGTCGACGCTGCCGCTCGCGCTCGAGCAGTTGCGCGGCGAAGGCCGGCTCGCA
CGCGGCACGCGCGCCATGCTGCTCGGATTCGGCGTCGGCTACTCTTGGGCCGGCTGTCTGTTGAACTGTTAG

Upstream 100 bases:

>100_bases
CGCGCGACACGTCGCGCCGGGTGCTCTGCCTGCCGATCTATCCGGAACTGTCGGACGCCAACGTGGAACGCATCGTCTCT
CTGATTGCGGAGGCGCGCTG

Downstream 100 bases:

>100_bases
TTTTAGGCAGGAATTCTAATGAACGCATTCTACGAAGGGCTCGCGGAAGTCTTTGAAATCGACACCGCCGAGGTGTCCCC
CGCACTGGTACTCGCCGATT

Product: putative 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAARATILDIASHLPAMVLGNDALAALYPEWPAEKILAKTGIRERRVAADDETASDLAFEAARRLFAQGSVRADEIDFVI
LCTQAPDYVLPASACVLQHRLGIPTHAGAFDVNLGCSGYVYGLSLAKGLIETGAARCVLLLTADTYSKYLHPLDKSVRTL
FGDGATATAIGLDERAADAEAEHIGPFVFGTDGRGAQNLIVRAGLFREPRSAKSAREHEDASGNVRTDEHLYMNGAEVMA
FSLAEVPRAADRLLERACLTRDDIDCFVLHQANRFMLEALRKKMKVPEDRFPILMEYTGNTVSSTLPLALEQLRGEGRLA
RGTRAMLLGFGVGYSWAGCLLNC

Sequences:

>Translated_343_residues
MAARATILDIASHLPAMVLGNDALAALYPEWPAEKILAKTGIRERRVAADDETASDLAFEAARRLFAQGSVRADEIDFVI
LCTQAPDYVLPASACVLQHRLGIPTHAGAFDVNLGCSGYVYGLSLAKGLIETGAARCVLLLTADTYSKYLHPLDKSVRTL
FGDGATATAIGLDERAADAEAEHIGPFVFGTDGRGAQNLIVRAGLFREPRSAKSAREHEDASGNVRTDEHLYMNGAEVMA
FSLAEVPRAADRLLERACLTRDDIDCFVLHQANRFMLEALRKKMKVPEDRFPILMEYTGNTVSSTLPLALEQLRGEGRLA
RGTRAMLLGFGVGYSWAGCLLNC
>Mature_342_residues
AARATILDIASHLPAMVLGNDALAALYPEWPAEKILAKTGIRERRVAADDETASDLAFEAARRLFAQGSVRADEIDFVIL
CTQAPDYVLPASACVLQHRLGIPTHAGAFDVNLGCSGYVYGLSLAKGLIETGAARCVLLLTADTYSKYLHPLDKSVRTLF
GDGATATAIGLDERAADAEAEHIGPFVFGTDGRGAQNLIVRAGLFREPRSAKSAREHEDASGNVRTDEHLYMNGAEVMAF
SLAEVPRAADRLLERACLTRDDIDCFVLHQANRFMLEALRKKMKVPEDRFPILMEYTGNTVSSTLPLALEQLRGEGRLAR
GTRAMLLGFGVGYSWAGCLLNC

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=339, Percent_Identity=29.7935103244838, Blast_Score=158, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37157; Mature: 37026

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARATILDIASHLPAMVLGNDALAALYPEWPAEKILAKTGIRERRVAADDETASDLAFE
CCCHHHHHHHHHHCCEEEECCCCCEEECCCCCHHHHHHHCCCHHHHCCCCCCHHHHHHHH
AARRLFAQGSVRADEIDFVILCTQAPDYVLPASACVLQHRLGIPTHAGAFDVNLGCSGYV
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCHHH
YGLSLAKGLIETGAARCVLLLTADTYSKYLHPLDKSVRTLFGDGATATAIGLDERAADAE
HHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHCCCC
AEHIGPFVFGTDGRGAQNLIVRAGLFREPRSAKSAREHEDASGNVRTDEHLYMNGAEVMA
HHHCCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEECCHHHHH
FSLAEVPRAADRLLERACLTRDDIDCFVLHQANRFMLEALRKKMKVPEDRFPILMEYTGN
HHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCC
TVSSTLPLALEQLRGEGRLARGTRAMLLGFGVGYSWAGCLLNC
CHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHCCC
>Mature Secondary Structure 
AARATILDIASHLPAMVLGNDALAALYPEWPAEKILAKTGIRERRVAADDETASDLAFE
CCHHHHHHHHHHCCEEEECCCCCEEECCCCCHHHHHHHCCCHHHHCCCCCCHHHHHHHH
AARRLFAQGSVRADEIDFVILCTQAPDYVLPASACVLQHRLGIPTHAGAFDVNLGCSGYV
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCHHH
YGLSLAKGLIETGAARCVLLLTADTYSKYLHPLDKSVRTLFGDGATATAIGLDERAADAE
HHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHCCCC
AEHIGPFVFGTDGRGAQNLIVRAGLFREPRSAKSAREHEDASGNVRTDEHLYMNGAEVMA
HHHCCCEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEECCHHHHH
FSLAEVPRAADRLLERACLTRDDIDCFVLHQANRFMLEALRKKMKVPEDRFPILMEYTGN
HHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCC
TVSSTLPLALEQLRGEGRLARGTRAMLLGFGVGYSWAGCLLNC
CHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]