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The map label for this gene is ispH1 [H]

Identifier: 238025521

GI number: 238025521

Start: 2751278

End: 2752219

Strand: Direct

Name: ispH1 [H]

Synonym: bglu_2g22170

Alternate gene names: 238025521

Gene position: 2751278-2752219 (Clockwise)

Preceding gene: 238025519

Following gene: 238025522

Centisome position: 97.31

GC content: 67.73

Gene sequence:

>942_bases
ATGCGAGTCATTCTTGCCCAACCCCGTGGCTTCTGTGCGGGCGTGGTCCGTGCCATCGAGATCGTCGATCGGGCGCTGCA
GCAGCATGGCGCGCCCGTCTACGTCCGGCACGAAATCGTCCACAATCGCCACGTGGTAGACAATCTGCGGAACAAGGGAG
CGAAATTCGTCGAGGAGCTGCACGAGGTGCCGCACGGCGCCGTGGCGATCTTCAGCGCGCACGGCGTGGCCCAGGCCGTC
GAGCAGGACGCGCAGGCCCGCGGCCTGGACGTGCTCGACGCCACCTGCCCGCTCGTCACGAAGGTGCACGTGCAGGGGCG
GCAGTACGTGTCGGCCGGGCGCCGCCTGATCCTGATCGGCCATGCCGGCCATCCGGAGGTGGAAGGCACGATCGGGCAAA
TTCCCGGCGAAGTGATCCTGGTGCAGAGCGAGGCCGAGGTCGAGACGCTGGAACTTCCGGCGCAGACGCCGATCGCCTAC
GTCACGCAAACCACGTTGTCGGTGGACGATACGCGCGGCATCATCGAGGCGCTGACGCGCCGCTTCACCGACATCGTCGG
CCCCGACACGCGCGATATCTGCTACGCCACCCAGAACCGCCAGGCCGCCGTGCGCGAGCTGAGCGGCCAGGTGGACGTGC
TGGTCGTGGTGGGCGCGACCAACAGTTCCAACTCGAACCGCCTGCGCGAGATCGGCACCGAAAGCGGCGTGCCGAGCTAT
CTCGTCGCCGACGGCTCCGAGATCCGCGCCGAATGGTTCAACGGCGCGCACACGGTCGGCCTGACCGCGGGCGCGTCCGC
GCCCGAGGAAATGGTCGAGGACGTGATCGGCGCGCTGCGCGCCCTGGGCCCCGTGGAGGTCGTCACGATGGCGGGCCGCG
AGGAAAAAGTCGAATTCAAGTTGCCGGCGAAGCTCATGCAAGCTGTCGCCCGCGAAGTTTAA

Upstream 100 bases:

>100_bases
ATGCCGGCAAGTTCCGATCCGGCATTGATAAACATCAAGTTGGGGCGATCGAGCCGGCCGGCTCTCTCGAACCCCGCGTT
GTCGTCGGAGTTCGCCCTGT

Downstream 100 bases:

>100_bases
GGAGGACATCTCTTGTCTATTCCGCTGCTCCAGCAAGTCCGTGTGGGCGCATACATCATGCGCAACCACCTGTCCGGCAA
TAAACGCTACCCGCTCGCGC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVDNLRNKGAKFVEELHEVPHGAVAIFSAHGVAQAV
EQDAQARGLDVLDATCPLVTKVHVQGRQYVSAGRRLILIGHAGHPEVEGTIGQIPGEVILVQSEAEVETLELPAQTPIAY
VTQTTLSVDDTRGIIEALTRRFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLVVVGATNSSNSNRLREIGTESGVPSY
LVADGSEIRAEWFNGAHTVGLTAGASAPEEMVEDVIGALRALGPVEVVTMAGREEKVEFKLPAKLMQAVAREV

Sequences:

>Translated_313_residues
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVDNLRNKGAKFVEELHEVPHGAVAIFSAHGVAQAV
EQDAQARGLDVLDATCPLVTKVHVQGRQYVSAGRRLILIGHAGHPEVEGTIGQIPGEVILVQSEAEVETLELPAQTPIAY
VTQTTLSVDDTRGIIEALTRRFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLVVVGATNSSNSNRLREIGTESGVPSY
LVADGSEIRAEWFNGAHTVGLTAGASAPEEMVEDVIGALRALGPVEVVTMAGREEKVEFKLPAKLMQAVAREV
>Mature_313_residues
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVDNLRNKGAKFVEELHEVPHGAVAIFSAHGVAQAV
EQDAQARGLDVLDATCPLVTKVHVQGRQYVSAGRRLILIGHAGHPEVEGTIGQIPGEVILVQSEAEVETLELPAQTPIAY
VTQTTLSVDDTRGIIEALTRRFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLVVVGATNSSNSNRLREIGTESGVPSY
LVADGSEIRAEWFNGAHTVGLTAGASAPEEMVEDVIGALRALGPVEVVTMAGREEKVEFKLPAKLMQAVAREV

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=308, Percent_Identity=53.8961038961039, Blast_Score=336, Evalue=9e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 33682; Mature: 33682

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVDNLRNKGAKFVEEL
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHHH
HEVPHGAVAIFSAHGVAQAVEQDAQARGLDVLDATCPLVTKVHVQGRQYVSAGRRLILIG
HHCCCCEEEEEEHHHHHHHHHHHHHHCCCCHHHCCCCHHEEEECCCHHHHHCCCEEEEEE
HAGHPEVEGTIGQIPGEVILVQSEAEVETLELPAQTPIAYVTQTTLSVDDTRGIIEALTR
CCCCCCCCCHHHCCCCEEEEEECCCCCEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHH
RFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLVVVGATNSSNSNRLREIGTESGVPSY
HHHHHCCCCCCCEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCE
LVADGSEIRAEWFNGAHTVGLTAGASAPEEMVEDVIGALRALGPVEVVTMAGREEKVEFK
EEECCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
LPAKLMQAVAREV
CCHHHHHHHHHCC
>Mature Secondary Structure
MRVILAQPRGFCAGVVRAIEIVDRALQQHGAPVYVRHEIVHNRHVVDNLRNKGAKFVEEL
CEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHHH
HEVPHGAVAIFSAHGVAQAVEQDAQARGLDVLDATCPLVTKVHVQGRQYVSAGRRLILIG
HHCCCCEEEEEEHHHHHHHHHHHHHHCCCCHHHCCCCHHEEEECCCHHHHHCCCEEEEEE
HAGHPEVEGTIGQIPGEVILVQSEAEVETLELPAQTPIAYVTQTTLSVDDTRGIIEALTR
CCCCCCCCCHHHCCCCEEEEEECCCCCEEEECCCCCCEEEEEEEEECCCHHHHHHHHHHH
RFTDIVGPDTRDICYATQNRQAAVRELSGQVDVLVVVGATNSSNSNRLREIGTESGVPSY
HHHHHCCCCCCCEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHCCCCCCCCE
LVADGSEIRAEWFNGAHTVGLTAGASAPEEMVEDVIGALRALGPVEVVTMAGREEKVEFK
EEECCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEE
LPAKLMQAVAREV
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA