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The map label for this gene is btr [H]

Identifier: 238025356

GI number: 238025356

Start: 2518210

End: 2518983

Strand: Direct

Name: btr [H]

Synonym: bglu_2g20320

Alternate gene names: 238025356

Gene position: 2518210-2518983 (Clockwise)

Preceding gene: 238025355

Following gene: 238025359

Centisome position: 89.07

GC content: 67.57

Gene sequence:

>774_bases
ATGCCCAGCCACATGGATAGGACCATCAGTGCGCCGAGCGAGCCGGGCAGCCGCCCGCCGGCCCTGTCGCGCCGCGACTG
GCCGCAGCGCGGCGAGGCGCGCTGTTCCGCCTGCGCGCTGCGGCCGGCGTGCCTGCCGCTCGGGCTGACGGCAACCGAGC
TGGCGCAGCTCGATTCGCTGGTTTGCACGACCCGCCTGATACACCGCGGCAAGACGCTGTATCGCGCCGGCGATCGCTTC
CGCAGCATCTACGCCGTGCGCACCGGCTCGTCCAAGACCGTCGTCACGCATCGCGACGGACACGAGCAGATCACCGGCTT
CCAGATCATCGGCGATACCCTCGGCCTGGACGGCATCCACGCCGGCCGGCACAACTGCGATGCCATCGCGCTCGAGGACA
GCACCGTCTGCATCATCCCCTTCGAGCGACTCGATCAGATCTGCCACGAGATCAAGGCGCTGCAGCAGCACGTCTACCAG
ATCCTGAGCGGCGAGATCGTGCGCGAATCCTCGCTGCTGCTGCTGCTCGGCACGATGACCGCGGAGCAGCGCGTGGCCGC
GTTCCTGCTGAACCTGTCGGAGCGTTACCGCGCGCGCGGCTATTCGTCAGTGGAGTTCAATCTGCGGATGAGCCGGGACG
AGATCGGCAGCTACCTCGGCCTGAAGCTGGAAACGGTCAGCCGCATGTTCTCGCGGCTCCAGCGCACCGGCATCGTCGCG
GCCAACGGCAAGCAGATCTACATCATCGACGCCGAGCGGCTGCGCGAGATCTGA

Upstream 100 bases:

>100_bases
TCACCGGTTGCGGCCCGCCCCGGGCCTCGGCCGCGCGTGGTCGGCAGGCTTGCGCGCGGGCAGCCCGGCGCGCTGCCCAT
CGCTTCCCCAGGAGCCAATG

Downstream 100 bases:

>100_bases
GGCCGGGGCCGGCCGGGCGCCGCCGCTGGCCGAGCGCCGCGGCACGCCGGCCGCCGGCCGGGCTGCCCGCCCGGTAGCGG
CGGTGCTCCTGCCGGGCTCG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPSHMDRTISAPSEPGSRPPALSRRDWPQRGEARCSACALRPACLPLGLTATELAQLDSLVCTTRLIHRGKTLYRAGDRF
RSIYAVRTGSSKTVVTHRDGHEQITGFQIIGDTLGLDGIHAGRHNCDAIALEDSTVCIIPFERLDQICHEIKALQQHVYQ
ILSGEIVRESSLLLLLGTMTAEQRVAAFLLNLSERYRARGYSSVEFNLRMSRDEIGSYLGLKLETVSRMFSRLQRTGIVA
ANGKQIYIIDAERLREI

Sequences:

>Translated_257_residues
MPSHMDRTISAPSEPGSRPPALSRRDWPQRGEARCSACALRPACLPLGLTATELAQLDSLVCTTRLIHRGKTLYRAGDRF
RSIYAVRTGSSKTVVTHRDGHEQITGFQIIGDTLGLDGIHAGRHNCDAIALEDSTVCIIPFERLDQICHEIKALQQHVYQ
ILSGEIVRESSLLLLLGTMTAEQRVAAFLLNLSERYRARGYSSVEFNLRMSRDEIGSYLGLKLETVSRMFSRLQRTGIVA
ANGKQIYIIDAERLREI
>Mature_256_residues
PSHMDRTISAPSEPGSRPPALSRRDWPQRGEARCSACALRPACLPLGLTATELAQLDSLVCTTRLIHRGKTLYRAGDRFR
SIYAVRTGSSKTVVTHRDGHEQITGFQIIGDTLGLDGIHAGRHNCDAIALEDSTVCIIPFERLDQICHEIKALQQHVYQI
LSGEIVRESSLLLLLGTMTAEQRVAAFLLNLSERYRARGYSSVEFNLRMSRDEIGSYLGLKLETVSRMFSRLQRTGIVAA
NGKQIYIIDAERLREI

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=223, Percent_Identity=43.0493273542601, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28677; Mature: 28546

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSHMDRTISAPSEPGSRPPALSRRDWPQRGEARCSACALRPACLPLGLTATELAQLDSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHCCCCCCHHHHHHHHHH
VCTTRLIHRGKTLYRAGDRFRSIYAVRTGSSKTVVTHRDGHEQITGFQIIGDTLGLDGIH
HHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCEEEEECCCCCHHCCEEEECCCCCCCCCC
AGRHNCDAIALEDSTVCIIPFERLDQICHEIKALQQHVYQILSGEIVRESSLLLLLGTMT
CCCCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
AEQRVAAFLLNLSERYRARGYSSVEFNLRMSRDEIGSYLGLKLETVSRMFSRLQRTGIVA
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHCCEEE
ANGKQIYIIDAERLREI
ECCCEEEEEEHHHHHCC
>Mature Secondary Structure 
PSHMDRTISAPSEPGSRPPALSRRDWPQRGEARCSACALRPACLPLGLTATELAQLDSL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHCCCCCCHHHHHHHHHH
VCTTRLIHRGKTLYRAGDRFRSIYAVRTGSSKTVVTHRDGHEQITGFQIIGDTLGLDGIH
HHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCEEEEECCCCCHHCCEEEECCCCCCCCCC
AGRHNCDAIALEDSTVCIIPFERLDQICHEIKALQQHVYQILSGEIVRESSLLLLLGTMT
CCCCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
AEQRVAAFLLNLSERYRARGYSSVEFNLRMSRDEIGSYLGLKLETVSRMFSRLQRTGIVA
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHCCEEE
ANGKQIYIIDAERLREI
ECCCEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]