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The map label for this gene is gacA [H]

Identifier: 238025278

GI number: 238025278

Start: 2426322

End: 2426966

Strand: Direct

Name: gacA [H]

Synonym: bglu_2g19520

Alternate gene names: 238025278

Gene position: 2426322-2426966 (Clockwise)

Preceding gene: 238025275

Following gene: 238025279

Centisome position: 85.82

GC content: 65.27

Gene sequence:

>645_bases
ATGAATTCATACGATTTTATCGTGGTCGACGGCGATCCGATTCTTCGACTCGGCGTCGGCGCATTGCTGGCGCGGAGCAA
GAACGGGGCGAGAGTCGCGGAAATCGCGCCGGGCGAGAGTATCAGGAATGTCGAGGTCGGCGCGGCGCAGCTCGTCACGC
TGGTCGCCAGCGGGCGGCTCGAATACGCGCCGGAGCGCGTGCGGGAAATCAGGAGCCACGCGCCCGACGTGCCGCTGCTC
GTGCTCGCCTCGGGCGCCGACGACGACAACGCGATTCGGATGCTGCGGGCCGGCGCGACCAGCTATGTCCGGCACTCGGC
CGATATTGCCGATCTGCTGGCCGCGATCGATGCAACCTGCCGCCGGCAGCGCTTTCTCGGGGCGGACGTGGCGGCGGGGC
TGTCGGACCGGCTGCTGCTGGGCCAGCGCCAGCGGCACGAAGACCTGTCGAATCGTGAATTGCAGATGCTGGTTCGCCTC
GCCGACGGACAAAGGGTGAAGGACATCGCCAGCGAGCTGTGCCTGTCCGTGAAGACGATCAGCAGCTACCGCGCGAGATT
GCTGGAAAAGCTCGATTTCAAATCCAACGCGGATCTGACGCGCTACGCGCTGGCCAACGCGCTGATTGCCAACGTCGCGA
GATAA

Upstream 100 bases:

>100_bases
TCCGAACCCGTTCGGACGGCGGCCGATCGGCATCACGCGCGCAGCGCCCCAGGAGGCCCGAGATTCGGGCGCGGACCTTG
CAGTTTGTGAACGAGCACCC

Downstream 100 bases:

>100_bases
CCGGACAGACAGGATGCCGGCAGGACGCCGGCTTTCAGACGAATCATTTAGGCATCCGTTGGAATGGATGCCGCGAAGCG
AACGGTCAAGAACGGCCGCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Global activator [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNSYDFIVVDGDPILRLGVGALLARSKNGARVAEIAPGESIRNVEVGAAQLVTLVASGRLEYAPERVREIRSHAPDVPLL
VLASGADDDNAIRMLRAGATSYVRHSADIADLLAAIDATCRRQRFLGADVAAGLSDRLLLGQRQRHEDLSNRELQMLVRL
ADGQRVKDIASELCLSVKTISSYRARLLEKLDFKSNADLTRYALANALIANVAR

Sequences:

>Translated_214_residues
MNSYDFIVVDGDPILRLGVGALLARSKNGARVAEIAPGESIRNVEVGAAQLVTLVASGRLEYAPERVREIRSHAPDVPLL
VLASGADDDNAIRMLRAGATSYVRHSADIADLLAAIDATCRRQRFLGADVAAGLSDRLLLGQRQRHEDLSNRELQMLVRL
ADGQRVKDIASELCLSVKTISSYRARLLEKLDFKSNADLTRYALANALIANVAR
>Mature_214_residues
MNSYDFIVVDGDPILRLGVGALLARSKNGARVAEIAPGESIRNVEVGAAQLVTLVASGRLEYAPERVREIRSHAPDVPLL
VLASGADDDNAIRMLRAGATSYVRHSADIADLLAAIDATCRRQRFLGADVAAGLSDRLLLGQRQRHEDLSNRELQMLVRL
ADGQRVKDIASELCLSVKTISSYRARLLEKLDFKSNADLTRYALANALIANVAR

Specific function: Positively controls the production of the autoinducer N- butyryl-homoserine lactone and the formation of the virulence factors pyocyanine, cyanide, and lipase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=210, Percent_Identity=27.1428571428571, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788712, Length=120, Percent_Identity=31.6666666666667, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23244; Mature: 23244

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSYDFIVVDGDPILRLGVGALLARSKNGARVAEIAPGESIRNVEVGAAQLVTLVASGRL
CCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
EYAPERVREIRSHAPDVPLLVLASGADDDNAIRMLRAGATSYVRHSADIADLLAAIDATC
CCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
RRQRFLGADVAAGLSDRLLLGQRQRHEDLSNRELQMLVRLADGQRVKDIASELCLSVKTI
HHHHHCCHHHHCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SSYRARLLEKLDFKSNADLTRYALANALIANVAR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSYDFIVVDGDPILRLGVGALLARSKNGARVAEIAPGESIRNVEVGAAQLVTLVASGRL
CCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
EYAPERVREIRSHAPDVPLLVLASGADDDNAIRMLRAGATSYVRHSADIADLLAAIDATC
CCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
RRQRFLGADVAAGLSDRLLLGQRQRHEDLSNRELQMLVRLADGQRVKDIASELCLSVKTI
HHHHHCCHHHHCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SSYRARLLEKLDFKSNADLTRYALANALIANVAR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9159518; 10984043 [H]