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The map label for this gene is lepB [H]

Identifier: 238025254

GI number: 238025254

Start: 2398790

End: 2399476

Strand: Direct

Name: lepB [H]

Synonym: bglu_2g19260

Alternate gene names: 238025254

Gene position: 2398790-2399476 (Clockwise)

Preceding gene: 238025251

Following gene: 238025255

Centisome position: 84.84

GC content: 68.41

Gene sequence:

>687_bases
ATGCGCATGATCGTCAGGCTCTGGAAAGCCAACAAGGGCTTCCTCGCGTTTCTGTTTCTGATGGTGATCTTCCGCAGCGC
GATAGCCGACTGGAACGTGGTGCCGAGCGGCTCGATGCTGCCGACCATCCGCATCGGCGACCGGATCCTCGTCGACAAGA
TGGCCTACGACCTGCGCGTGCCGTTTACGCACATCCGTCTGGCGCGGCTGCACGAACCGCAGCGCGGCGATATCGTGACG
ATCGACTCGGCCGCCGCACACGAGCTGCTGGTCAAGCGGCTGATCGGCCTGCCCGGCGACACCGTGGAGCTGCGCAACAA
CGTGCTGCTGATCAACGGGGTGCGCGCCGCCTACCGGCCGGTGGGCACCAACCTGCTGCGCAGCGATGCCGCCTCGCCCG
GCGAATACCTGGCCGAGCGCATCGACGGCAGCGCGCGCATCGTGCGGCTCTCGCCCGACGCGCCGAGCCCGCGCGATTCG
TTCGGCCCGGTCGTGGTGCCGAAGGGGCAGTACCTGATGCTCGGCGACAATCGCGACAACAGCGCCGATTCGCGCTATTT
CGGCTTCTTCCCGCGCGACGAGATCATGGGCCGCGCGCGGCGCGTGGCGTTCTCGCTCGATCCCTCGCACGACTACCTGC
CGCGCCTGGACCGCTTCGGGCGCCGGCTCGACGCGCCGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGCCGTGCCGCCCGCGCCACCCCACCCAACGCAACGCCGCGGGCGCTTCGGGTATAGTCGGCTTACCCGAAACATCGGCC
GCGACGCGGCCCACCCCACC

Downstream 100 bases:

>100_bases
ACCAGGCGGCGGCTCCGCCCCGTCCATCGCCCCCATGCCATGAAACGAATCGTCCGCGCCGCCGTGGCGGCGCTCGCCCT
CGGCGCCGGCAGCGGCGCGT

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRMIVRLWKANKGFLAFLFLMVIFRSAIADWNVVPSGSMLPTIRIGDRILVDKMAYDLRVPFTHIRLARLHEPQRGDIVT
IDSAAAHELLVKRLIGLPGDTVELRNNVLLINGVRAAYRPVGTNLLRSDAASPGEYLAERIDGSARIVRLSPDAPSPRDS
FGPVVVPKGQYLMLGDNRDNSADSRYFGFFPRDEIMGRARRVAFSLDPSHDYLPRLDRFGRRLDAPLG

Sequences:

>Translated_228_residues
MRMIVRLWKANKGFLAFLFLMVIFRSAIADWNVVPSGSMLPTIRIGDRILVDKMAYDLRVPFTHIRLARLHEPQRGDIVT
IDSAAAHELLVKRLIGLPGDTVELRNNVLLINGVRAAYRPVGTNLLRSDAASPGEYLAERIDGSARIVRLSPDAPSPRDS
FGPVVVPKGQYLMLGDNRDNSADSRYFGFFPRDEIMGRARRVAFSLDPSHDYLPRLDRFGRRLDAPLG
>Mature_228_residues
MRMIVRLWKANKGFLAFLFLMVIFRSAIADWNVVPSGSMLPTIRIGDRILVDKMAYDLRVPFTHIRLARLHEPQRGDIVT
IDSAAAHELLVKRLIGLPGDTVELRNNVLLINGVRAAYRPVGTNLLRSDAASPGEYLAERIDGSARIVRLSPDAPSPRDS
FGPVVVPKGQYLMLGDNRDNSADSRYFGFFPRDEIMGRARRVAFSLDPSHDYLPRLDRFGRRLDAPLG

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=251, Percent_Identity=31.4741035856574, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 25595; Mature: 25595

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMIVRLWKANKGFLAFLFLMVIFRSAIADWNVVPSGSMLPTIRIGDRILVDKMAYDLRV
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHEEC
PFTHIRLARLHEPQRGDIVTIDSAAAHELLVKRLIGLPGDTVELRNNVLLINGVRAAYRP
CHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEECCCCEEEEECCHHHHHH
VGTNLLRSDAASPGEYLAERIDGSARIVRLSPDAPSPRDSFGPVVVPKGQYLMLGDNRDN
CCHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCC
SADSRYFGFFPRDEIMGRARRVAFSLDPSHDYLPRLDRFGRRLDAPLG
CCCCCEECCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRMIVRLWKANKGFLAFLFLMVIFRSAIADWNVVPSGSMLPTIRIGDRILVDKMAYDLRV
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHEEC
PFTHIRLARLHEPQRGDIVTIDSAAAHELLVKRLIGLPGDTVELRNNVLLINGVRAAYRP
CHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCEEECCCCEEEEECCHHHHHH
VGTNLLRSDAASPGEYLAERIDGSARIVRLSPDAPSPRDSFGPVVVPKGQYLMLGDNRDN
CCHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCC
SADSRYFGFFPRDEIMGRARRVAFSLDPSHDYLPRLDRFGRRLDAPLG
CCCCCEECCCCHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]