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The map label for this gene is mocR [H]

Identifier: 238025238

GI number: 238025238

Start: 2383011

End: 2384489

Strand: Direct

Name: mocR [H]

Synonym: bglu_2g19100

Alternate gene names: 238025238

Gene position: 2383011-2384489 (Clockwise)

Preceding gene: 238025237

Following gene: 238025241

Centisome position: 84.28

GC content: 72.75

Gene sequence:

>1479_bases
ATGACCCACCGCGACCGCGACCTGAAGCTCGACATCGACCGGCGCCTGCAGTTGCCCATCTACCTGCAGATCTGCGAGCG
CTTCAAGCTCGCGATCCGCGCCGGGCACCTGCGCCCCGGCGATCGCGTGCCCGCCGTGCGCGGCCTCGCCACCGAGTTGA
ACACGGCGCGCGGCACGATCGAAACGGCCTACCGGATTCTCATCGACGAAGGCTATCTGCAGGTGCGCGGCGCGGCCGGC
ACCTATGTCTCGCCGTCGCTGCCGCAGGCGGCGCTGCGCGGCGCGGCGCGAGCTTCGCGCGCCAGCGCCGCCGCGCCGAA
GGACAAGCCGGCCGCAGCCGATCCCGGCCGCCCGCCCGGCGAGCGCGGCAGCGAACCGCTGCCGCTGCAGCCGGGGCTGC
CCGCACTCGACGCGTTCCCGCGCAAGGTCTGGAGCCGGCTGGTCGCCTACCGCCTGCGGCGCGCCGAAACGGCCTCGCTC
GCCTATCCCGATCCGCGCGGCTATCTGCTGCTGCGCGAGAAGATCGCCACCTACCTCGGACTGTCGCGCGGCGTGGCATG
CACGCCGGACCAGGTATTCGTGACGGGCGGCTATCGCGCCACGCTCGAACTGGTGCTGCGTGCGCTCGCCGCGCCGGGCG
AGCGCATGTGGTTCGAGGATCCCGGCTATCTGCTCGCGCGGCGCTTTCTGGTCGATGCGGGCATGGAACTGGTGCCGGTG
CCGGTGGATGCCGAGGGGCTGATGGTGGAACGCGGCGCGGCACTCGCCCCCGAGGCGCGCTTCGCGGTGGTGACGCCCTC
GCACCAGAGCCCGCTCGGCGTCACGCTCTCGCTGTCACGCCGCATGGCGCTGCTGGACTGGGCCTCGCGCGCCGGCAGCT
GGGTGATCGAGGACGACTACGATAGCGAGTTCCGCTACGCGGGCCGGCCGCTGCCCGCGCTGAAGAGCCTGGACCGGCAC
GACCGCGTGATCTATTGCGGCACCTTCAGCAAGGTAATGGTGCCGGGCCTGCGGCTCGCCTACGTGGTGGTGCCCGAGCG
CGCCACCGCGCGCCTCCTGCGGATCTGCCAGACCATGAACGCCGCCTCGCCGTACCTGCTGCAGGCCGGCGTGGCCGACT
TCATCGCGCAGGGCCATTTCGCGCGGCACCTGAAACGGATGCGCGCGCTGTATGCGGAGCGCCGCGGGCTGATGGTGGAG
GCGCTGCGCGACGCGTTCGGCGCGCGGCTGCGCATCGACGTGCCGCCGGGCGGCATGCATCTCGCGATCGGCTTCGAAGG
CGCTGCGGCGATCGACGATCTCGACTTCGCCGCGCGCGCGCGCGCGGCGGGGCTCGGCGTCAGCGCGCTGTCGGAGTGGT
ATGCGAACAGCCGCGCGAAGCAGACGCGGCGCGGTGCCGTGCTCGGCTTCGCCAACGTGATCGACCGCGAGGCCGCGCAG
CGCTACGCGCGGGCGCTGCGGCAGGTCTACGACGCCTAG

Upstream 100 bases:

>100_bases
GAACGTCCGGCCCGGCGCCGGCGCCACGTTCCTCATGCGACAATGACGGCTCACTGATTTCACACGCTTCACCACACCCG
AGCAGTCCAACAGTCCCCCG

Downstream 100 bases:

>100_bases
CCGGGGCCGACACGGTTGCGCATGCGCGGGCGGGCGGACCGCCGGCGAAACCGGGCCGGGCGCGGCTCGAAGCCGACGCC
CCGCGCTGCGCAGCGGCGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MTHRDRDLKLDIDRRLQLPIYLQICERFKLAIRAGHLRPGDRVPAVRGLATELNTARGTIETAYRILIDEGYLQVRGAAG
TYVSPSLPQAALRGAARASRASAAAPKDKPAAADPGRPPGERGSEPLPLQPGLPALDAFPRKVWSRLVAYRLRRAETASL
AYPDPRGYLLLREKIATYLGLSRGVACTPDQVFVTGGYRATLELVLRALAAPGERMWFEDPGYLLARRFLVDAGMELVPV
PVDAEGLMVERGAALAPEARFAVVTPSHQSPLGVTLSLSRRMALLDWASRAGSWVIEDDYDSEFRYAGRPLPALKSLDRH
DRVIYCGTFSKVMVPGLRLAYVVVPERATARLLRICQTMNAASPYLLQAGVADFIAQGHFARHLKRMRALYAERRGLMVE
ALRDAFGARLRIDVPPGGMHLAIGFEGAAAIDDLDFAARARAAGLGVSALSEWYANSRAKQTRRGAVLGFANVIDREAAQ
RYARALRQVYDA

Sequences:

>Translated_492_residues
MTHRDRDLKLDIDRRLQLPIYLQICERFKLAIRAGHLRPGDRVPAVRGLATELNTARGTIETAYRILIDEGYLQVRGAAG
TYVSPSLPQAALRGAARASRASAAAPKDKPAAADPGRPPGERGSEPLPLQPGLPALDAFPRKVWSRLVAYRLRRAETASL
AYPDPRGYLLLREKIATYLGLSRGVACTPDQVFVTGGYRATLELVLRALAAPGERMWFEDPGYLLARRFLVDAGMELVPV
PVDAEGLMVERGAALAPEARFAVVTPSHQSPLGVTLSLSRRMALLDWASRAGSWVIEDDYDSEFRYAGRPLPALKSLDRH
DRVIYCGTFSKVMVPGLRLAYVVVPERATARLLRICQTMNAASPYLLQAGVADFIAQGHFARHLKRMRALYAERRGLMVE
ALRDAFGARLRIDVPPGGMHLAIGFEGAAAIDDLDFAARARAAGLGVSALSEWYANSRAKQTRRGAVLGFANVIDREAAQ
RYARALRQVYDA
>Mature_491_residues
THRDRDLKLDIDRRLQLPIYLQICERFKLAIRAGHLRPGDRVPAVRGLATELNTARGTIETAYRILIDEGYLQVRGAAGT
YVSPSLPQAALRGAARASRASAAAPKDKPAAADPGRPPGERGSEPLPLQPGLPALDAFPRKVWSRLVAYRLRRAETASLA
YPDPRGYLLLREKIATYLGLSRGVACTPDQVFVTGGYRATLELVLRALAAPGERMWFEDPGYLLARRFLVDAGMELVPVP
VDAEGLMVERGAALAPEARFAVVTPSHQSPLGVTLSLSRRMALLDWASRAGSWVIEDDYDSEFRYAGRPLPALKSLDRHD
RVIYCGTFSKVMVPGLRLAYVVVPERATARLLRICQTMNAASPYLLQAGVADFIAQGHFARHLKRMRALYAERRGLMVEA
LRDAFGARLRIDVPPGGMHLAIGFEGAAAIDDLDFAARARAAGLGVSALSEWYANSRAKQTRRGAVLGFANVIDREAAQR
YARALRQVYDA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=284, Percent_Identity=22.5352112676056, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI33469970, Length=284, Percent_Identity=22.5352112676056, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787710, Length=429, Percent_Identity=28.2051282051282, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790797, Length=446, Percent_Identity=26.9058295964126, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53959; Mature: 53828

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHRDRDLKLDIDRRLQLPIYLQICERFKLAIRAGHLRPGDRVPAVRGLATELNTARGTI
CCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHH
ETAYRILIDEGYLQVRGAAGTYVSPSLPQAALRGAARASRASAAAPKDKPAAADPGRPPG
HHHHHHEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ERGSEPLPLQPGLPALDAFPRKVWSRLVAYRLRRAETASLAYPDPRGYLLLREKIATYLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHH
LSRGVACTPDQVFVTGGYRATLELVLRALAAPGERMWFEDPGYLLARRFLVDAGMELVPV
HCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEC
PVDAEGLMVERGAALAPEARFAVVTPSHQSPLGVTLSLSRRMALLDWASRAGSWVIEDDY
CCCCCCEEEECCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHCCCEEEECCC
DSEFRYAGRPLPALKSLDRHDRVIYCGTFSKVMVPGLRLAYVVVPERATARLLRICQTMN
CCCHHHCCCCCHHHHCCCCCCCEEEECCHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHC
AASPYLLQAGVADFIAQGHFARHLKRMRALYAERRGLMVEALRDAFGARLRIDVPPGGMH
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCEE
LAIGFEGAAAIDDLDFAARARAAGLGVSALSEWYANSRAKQTRRGAVLGFANVIDREAAQ
EEEECCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RYARALRQVYDA
HHHHHHHHHHCC
>Mature Secondary Structure 
THRDRDLKLDIDRRLQLPIYLQICERFKLAIRAGHLRPGDRVPAVRGLATELNTARGTI
CCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHH
ETAYRILIDEGYLQVRGAAGTYVSPSLPQAALRGAARASRASAAAPKDKPAAADPGRPPG
HHHHHHEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ERGSEPLPLQPGLPALDAFPRKVWSRLVAYRLRRAETASLAYPDPRGYLLLREKIATYLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHH
LSRGVACTPDQVFVTGGYRATLELVLRALAAPGERMWFEDPGYLLARRFLVDAGMELVPV
HCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEC
PVDAEGLMVERGAALAPEARFAVVTPSHQSPLGVTLSLSRRMALLDWASRAGSWVIEDDY
CCCCCCEEEECCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHCCCEEEECCC
DSEFRYAGRPLPALKSLDRHDRVIYCGTFSKVMVPGLRLAYVVVPERATARLLRICQTMN
CCCHHHCCCCCHHHHCCCCCCCEEEECCHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHC
AASPYLLQAGVADFIAQGHFARHLKRMRALYAERRGLMVEALRDAFGARLRIDVPPGGMH
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCCEE
LAIGFEGAAAIDDLDFAARARAAGLGVSALSEWYANSRAKQTRRGAVLGFANVIDREAAQ
EEEECCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RYARALRQVYDA
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]