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The map label for this gene is uxaB [H]

Identifier: 238025182

GI number: 238025182

Start: 2309346

End: 2310488

Strand: Direct

Name: uxaB [H]

Synonym: bglu_2g18530

Alternate gene names: 238025182

Gene position: 2309346-2310488 (Clockwise)

Preceding gene: 238025181

Following gene: 238025183

Centisome position: 81.68

GC content: 72.0

Gene sequence:

>1143_bases
ATGAGCGTCCCCATCCTCCAGTTCGGCACGAGCCGGTTCCTGCTCGCGCATGCCGCCTTCTTCGTGTCCGAGGCGCTCGC
GCGCGGCGAGGCGATCGGCAGCATCGGCGTGGTGCAGACCACCTCGAACCCGGCCAGCCGCGCCCGCATCGAGGCGCTGG
CCGCGGCCGGCCGCTATCCGGTGCGCATCCGCGGACTGGCCGACGGCGCCGTGATCGACCGCGTCGTGCCATGCGAGGCG
GTGCGCCAGGCCTGGACCGCCGCGGCCGACTGGGCCGCGATCCGCCAGGCCGTCGTCGACGAGGTGCGCGTCATCGTGTC
GAACACGGCCGATGCCGGCTACCGGCTCGACGCGCGCGACTCGGCCGAGGCGCTCGCCGACCCGGCCCGGGTGCCGCACA
GCTTCCCGGCGAAGCTGCTGACGCTGCTTCATGCGCGCTGGCAGCAGCGCCCCGACGACGGCCTCACGCTGCTGCCCTGC
GAGCTGATCGCGCACAACGGCGACACGCTGCGCGACATCGTGCTGGATCTGGCCCGGCAGTGGCGCCTGCCCGACGGCTT
GCTCGCCTACCTGCGGCACACCTGCGTCTGGGTGAATTCGCTCGTGGACCGGATCGTGTCCGAGGCGATCGATCCGGTGG
GCGCGATCGCCGAGCCATACGCACTGTGGGCCATCGAGCGGCAGGCCGGCATGACGCTGCCCTGCACGCACGAGCAGATC
GTCGTGACGGACGACCTGGTCAGCCACGAACGCCTGAAACTGTTCTTCCTCAACCTGGGCCACACCTGGCTGGCCGAGCA
GTGGCTGCGCGACGGCCGCCCGCCCGACGAAACGGTGCGCGAGGCGCTCGCCGATGCGCGGCTCAGCGACGGGATCGAGC
ACGTCTGGCGCGACGAGGTGCTGCCGGTGTTCGCGGCCCTGGGCCAGCGCGAGGCGGCCGAGCGCTATATCGACACGGTG
CGCGACCGTCTGCTCAACCCCTACCTGAACCACCGCATCGCGGACATCGCGACTCACCACGACGAAAAGATCCGGCGCCG
GATTCGCCCCTTGATCGCGCTGGCGGACGCGCATGTCCCGGGCCACGCCCAACCGCGCCTGCGCGGCCTGCTGGCCGGGC
GCGACCTGCCGGAACCGACTTGA

Upstream 100 bases:

>100_bases
GTGCCCGAGGCGCTGCCGCGGCTGCTCGAGCCGGGGCAGACCGTGGTGAAGGCGCTCGTCGAGTGTTGACCGGCATGCCA
ACGCAACCAGGACCCGCCGC

Downstream 100 bases:

>100_bases
GAGGAACACGCATCATGAATGCAGGCACGCTCCTGAAACTCCACCGCGACGACAACGTCGCGCTGGCCCTGCGCGCGCTC
GATGCCGGCGACGTCGTCGA

Product: Mannitol dehydrogenase-like protein

Products: NA

Alternate protein names: Tagaturonate dehydrogenase; Tagaturonate reductase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSVPILQFGTSRFLLAHAAFFVSEALARGEAIGSIGVVQTTSNPASRARIEALAAAGRYPVRIRGLADGAVIDRVVPCEA
VRQAWTAAADWAAIRQAVVDEVRVIVSNTADAGYRLDARDSAEALADPARVPHSFPAKLLTLLHARWQQRPDDGLTLLPC
ELIAHNGDTLRDIVLDLARQWRLPDGLLAYLRHTCVWVNSLVDRIVSEAIDPVGAIAEPYALWAIERQAGMTLPCTHEQI
VVTDDLVSHERLKLFFLNLGHTWLAEQWLRDGRPPDETVREALADARLSDGIEHVWRDEVLPVFAALGQREAAERYIDTV
RDRLLNPYLNHRIADIATHHDEKIRRRIRPLIALADAHVPGHAQPRLRGLLAGRDLPEPT

Sequences:

>Translated_380_residues
MSVPILQFGTSRFLLAHAAFFVSEALARGEAIGSIGVVQTTSNPASRARIEALAAAGRYPVRIRGLADGAVIDRVVPCEA
VRQAWTAAADWAAIRQAVVDEVRVIVSNTADAGYRLDARDSAEALADPARVPHSFPAKLLTLLHARWQQRPDDGLTLLPC
ELIAHNGDTLRDIVLDLARQWRLPDGLLAYLRHTCVWVNSLVDRIVSEAIDPVGAIAEPYALWAIERQAGMTLPCTHEQI
VVTDDLVSHERLKLFFLNLGHTWLAEQWLRDGRPPDETVREALADARLSDGIEHVWRDEVLPVFAALGQREAAERYIDTV
RDRLLNPYLNHRIADIATHHDEKIRRRIRPLIALADAHVPGHAQPRLRGLLAGRDLPEPT
>Mature_379_residues
SVPILQFGTSRFLLAHAAFFVSEALARGEAIGSIGVVQTTSNPASRARIEALAAAGRYPVRIRGLADGAVIDRVVPCEAV
RQAWTAAADWAAIRQAVVDEVRVIVSNTADAGYRLDARDSAEALADPARVPHSFPAKLLTLLHARWQQRPDDGLTLLPCE
LIAHNGDTLRDIVLDLARQWRLPDGLLAYLRHTCVWVNSLVDRIVSEAIDPVGAIAEPYALWAIERQAGMTLPCTHEQIV
VTDDLVSHERLKLFFLNLGHTWLAEQWLRDGRPPDETVREALADARLSDGIEHVWRDEVLPVFAALGQREAAERYIDTVR
DRLLNPYLNHRIADIATHHDEKIRRRIRPLIALADAHVPGHAQPRLRGLLAGRDLPEPT

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxaB subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994885, Length=393, Percent_Identity=28.7531806615776, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788497, Length=370, Percent_Identity=25.4054054054054, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.58 [H]

Molecular weight: Translated: 42170; Mature: 42038

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPILQFGTSRFLLAHAAFFVSEALARGEAIGSIGVVQTTSNPASRARIEALAAAGRYP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCC
VRIRGLADGAVIDRVVPCEAVRQAWTAAADWAAIRQAVVDEVRVIVSNTADAGYRLDARD
EEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
SAEALADPARVPHSFPAKLLTLLHARWQQRPDDGLTLLPCELIAHNGDTLRDIVLDLARQ
CHHHHHCHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHHH
WRLPDGLLAYLRHTCVWVNSLVDRIVSEAIDPVGAIAEPYALWAIERQAGMTLPCTHEQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHEEEHHHCCCCCCCCCCEE
VVTDDLVSHERLKLFFLNLGHTWLAEQWLRDGRPPDETVREALADARLSDGIEHVWRDEV
EEEHHHHHHHHHEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LPVFAALGQREAAERYIDTVRDRLLNPYLNHRIADIATHHDEKIRRRIRPLIALADAHVP
HHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
GHAQPRLRGLLAGRDLPEPT
CCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SVPILQFGTSRFLLAHAAFFVSEALARGEAIGSIGVVQTTSNPASRARIEALAAAGRYP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCC
VRIRGLADGAVIDRVVPCEAVRQAWTAAADWAAIRQAVVDEVRVIVSNTADAGYRLDARD
EEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
SAEALADPARVPHSFPAKLLTLLHARWQQRPDDGLTLLPCELIAHNGDTLRDIVLDLARQ
CHHHHHCHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCHHHHHHHHHHHH
WRLPDGLLAYLRHTCVWVNSLVDRIVSEAIDPVGAIAEPYALWAIERQAGMTLPCTHEQI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHEEEHHHCCCCCCCCCCEE
VVTDDLVSHERLKLFFLNLGHTWLAEQWLRDGRPPDETVREALADARLSDGIEHVWRDEV
EEEHHHHHHHHHEEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LPVFAALGQREAAERYIDTVRDRLLNPYLNHRIADIATHHDEKIRRRIRPLIALADAHVP
HHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
GHAQPRLRGLLAGRDLPEPT
CCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]