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The map label for this gene is degU [H]

Identifier: 238025165

GI number: 238025165

Start: 2290540

End: 2291256

Strand: Direct

Name: degU [H]

Synonym: bglu_2g18360

Alternate gene names: 238025165

Gene position: 2290540-2291256 (Clockwise)

Preceding gene: 238025164

Following gene: 339717980

Centisome position: 81.01

GC content: 70.71

Gene sequence:

>717_bases
ATGACGCTTCTGCCGCCGGAACCCATGGTGCCGGGCCCGCTACTCATCGTCGACGACGAGCCGATGATGCAGCGCCGGCT
GACCACGATCCTCACCTCGCTCGGCTATGCCGACGACGCCCTGCTGTTCGCCGACAGCCTCGCCCAGGCGCGCGCGACGC
GCGCCACCCAGCCCTGCGCGATCGCGCTGGTCGACATCGGCCTGCCCGACGGCTCGGGCATCGAGCTGATCCGCGAATGG
CACGAGGCCGACCCGGCGCTGCCGATCGTGGTGATCTCGACCTGGAGCACCGGGCCCACCATCGTCGGCGCGCTGCAGGC
CGGCGCGACCGGCTATCTGCTCAAGGAGCGCGACGACCTCGAAATCGCGCTGTCGATCCGCAGCGTGCTGCGCGGCGGCG
CGCCGATCGATCCGTTCGTGGCGCGCTACATCCTCGATAGCGTCAACGCGCCGCCGCCCGCCACCGCGCCCGCGGCCCCG
GCGAGCACCGTGACGCTGCCGTCGCGTGACGGCGCCCCGCCCGTGCGGCTCAGCCGCCGCGAGATCGAAATCCTCGGCAT
CGTCAGCAAGGGCCTGACCAATCGCGAAATCTCCGAGCTGCTGTCGCTGTCGAGGCTGACGGTCGAATGCCACATCAAGA
ACATCTACAAGAAGCTCGCGGTGCGCTCGCGCACGCAGGCCGTCTTCGAGGCCCGCGCCCACGGGCTGCTGCCCTGA

Upstream 100 bases:

>100_bases
GTGCTATCGTCGGCGCGAGTCTCGCGCCGGCCCGCGAACGCCCCACCCGGGTGCCCGTTCGCCTGCTTGCCATCCGATCC
AGCCACACAACACGCGACCC

Downstream 100 bases:

>100_bases
CGAGGCCCTCCGGCATGCAAGCAGCACCAAACTGCGATCACAGTTTGCCGTTCGCGGCCGGGCGCGCGGCCGCCGCATCG
CGCGCCGTGCGGCAGATGCC

Product: response regulator, NarL-family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MTLLPPEPMVPGPLLIVDDEPMMQRRLTTILTSLGYADDALLFADSLAQARATRATQPCAIALVDIGLPDGSGIELIREW
HEADPALPIVVISTWSTGPTIVGALQAGATGYLLKERDDLEIALSIRSVLRGGAPIDPFVARYILDSVNAPPPATAPAAP
ASTVTLPSRDGAPPVRLSRREIEILGIVSKGLTNREISELLSLSRLTVECHIKNIYKKLAVRSRTQAVFEARAHGLLP

Sequences:

>Translated_238_residues
MTLLPPEPMVPGPLLIVDDEPMMQRRLTTILTSLGYADDALLFADSLAQARATRATQPCAIALVDIGLPDGSGIELIREW
HEADPALPIVVISTWSTGPTIVGALQAGATGYLLKERDDLEIALSIRSVLRGGAPIDPFVARYILDSVNAPPPATAPAAP
ASTVTLPSRDGAPPVRLSRREIEILGIVSKGLTNREISELLSLSRLTVECHIKNIYKKLAVRSRTQAVFEARAHGLLP
>Mature_237_residues
TLLPPEPMVPGPLLIVDDEPMMQRRLTTILTSLGYADDALLFADSLAQARATRATQPCAIALVDIGLPDGSGIELIREWH
EADPALPIVVISTWSTGPTIVGALQAGATGYLLKERDDLEIALSIRSVLRGGAPIDPFVARYILDSVNAPPPATAPAAPA
STVTLPSRDGAPPVRLSRREIEILGIVSKGLTNREISELLSLSRLTVECHIKNIYKKLAVRSRTQAVFEARAHGLLP

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=217, Percent_Identity=26.2672811059908, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786747, Length=235, Percent_Identity=25.9574468085106, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788222, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25489; Mature: 25358

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLPPEPMVPGPLLIVDDEPMMQRRLTTILTSLGYADDALLFADSLAQARATRATQPCA
CCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEE
IALVDIGLPDGSGIELIREWHEADPALPIVVISTWSTGPTIVGALQAGATGYLLKERDDL
EEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHCCCCEEEEECCCCH
EIALSIRSVLRGGAPIDPFVARYILDSVNAPPPATAPAAPASTVTLPSRDGAPPVRLSRR
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCC
EIEILGIVSKGLTNREISELLSLSRLTVECHIKNIYKKLAVRSRTQAVFEARAHGLLP
EEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLLPPEPMVPGPLLIVDDEPMMQRRLTTILTSLGYADDALLFADSLAQARATRATQPCA
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEE
IALVDIGLPDGSGIELIREWHEADPALPIVVISTWSTGPTIVGALQAGATGYLLKERDDL
EEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEHHCCCCEEEEECCCCH
EIALSIRSVLRGGAPIDPFVARYILDSVNAPPPATAPAAPASTVTLPSRDGAPPVRLSRR
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEECCC
EIEILGIVSKGLTNREISELLSLSRLTVECHIKNIYKKLAVRSRTQAVFEARAHGLLP
EEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]