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The map label for this gene is 238025099

Identifier: 238025099

GI number: 238025099

Start: 2200146

End: 2201312

Strand: Direct

Name: 238025099

Synonym: bglu_2g17560

Alternate gene names: NA

Gene position: 2200146-2201312 (Clockwise)

Preceding gene: 238025098

Following gene: 238025102

Centisome position: 77.82

GC content: 69.58

Gene sequence:

>1167_bases
ATGCTGACCTCGCATCGCGAGCATCTGGAAGTCGCCTGGCCCGACGGCAGCACGAGCCGCTACCACTGGGTATGGCTGCG
CCAGGCGTGCCAATGCGCCAGCTGCTTCAACCGCCATTGCCGCCAGCGGCACTTCGATCCGGGCGTGGTGCCGGCCGACC
TGCGGCCGGCCGCCCTCAGCGCCGACGCCACGGGCCTGCGCATCGTCTGGCCGGATGGCCATCCGAGCCATTACGGCTTC
GACCGCCTGCGCGACGAGGACTACGACCAGCCACGACGCGCCGCACCGGCCGACGCCCGCCCCGCCTGGCGCCGCTGGCC
GGACGGCGCCCCGCCGGCGCTGCGCTTCGAGCTCGCCGCGGCGCTCGACGACGGCGCGCTGCTGCATCGGGCGCTGCAGC
ATCTGTTCGAATACGGGCTGGTGGTGCTGAAGGCGGAGCCGACGCGCACCGTCGAGTTCGGGGCGGTATGCCGGCAGCTG
GCGGGGTTTCTCGATCGCTCCTACTTCGGGGAGTTCTTCGATCTGGAAGTGAAGGCCGACGAGGAGACCGACAGCGTGTC
GTTCAGCACCAAGGCGCTGCCGCTGCACACCGACATCCCGTACTGCTCGCCGCCGCCCGACTACCAGTTCCTGTATGGCC
TCGACGTGAGTTCGCAATGCGCGCGAGACGGCATCGGCAGCACGCGTTTCGTGGACGGCTTCACGATCGCCTGCGAGCTG
CGCGAGGCCCAGCCCGATGCGTTCGCGCTGCTCGCCCGCACGCCGGTGCTCTATCGCGCCGACTATCCACAGGCACGCAA
GCGCTACGAGCATCGCACGCCGATCGTGCGGCTCGCGCCGGACGGCTCGATCGAACGCCTGATCAACAATCCGACGAAGA
TGTTCTTCGACGGCATCGGCTTCGACGAGATGCTGCCCCTCTTCCGTGCCTACCAGTCGCTCAAGTCGCGGCTGGCGGCG
ACCGAACGGTCGTACCTGCATGCGTGGTCGCAGGGCGACATGGTGGTCTGGGACAATCGCCGGATCTTCCATGGCCGCGG
CGACTTCGGTGGGTCCGGCTTCACGCGCACGCTGCGCGGCGGGTATTTCCGCGAAGGCGAACTGCTGGCGCGCGCACGCT
TCCTGGCGTCGCGCGCGGCCGACCGGCGCGCTGCGGTCGCTTCGTGA

Upstream 100 bases:

>100_bases
AAGATCCGCTTCATGAAGGCCGGCTGGCTGACGCAGGGCCTGTTCATGGCGGACAAGGCATGAGCGCGCTCGCTTGGCAG
TCCTACTGGAGATCCCTCAC

Downstream 100 bases:

>100_bases
GCGCCGCGCCCGGCCTGCCTCAGGCGCGATACGCGAGGCACGCGGCACCGGCCACGACCGCCGCGGCAGCCGCGATCCGC
TGCCCGGTCGGGCGCTCGCC

Product: putative gamma-butyrobetaine,2-oxoglutarate dioxygenase

Products: NA

Alternate protein names: Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MLTSHREHLEVAWPDGSTSRYHWVWLRQACQCASCFNRHCRQRHFDPGVVPADLRPAALSADATGLRIVWPDGHPSHYGF
DRLRDEDYDQPRRAAPADARPAWRRWPDGAPPALRFELAAALDDGALLHRALQHLFEYGLVVLKAEPTRTVEFGAVCRQL
AGFLDRSYFGEFFDLEVKADEETDSVSFSTKALPLHTDIPYCSPPPDYQFLYGLDVSSQCARDGIGSTRFVDGFTIACEL
REAQPDAFALLARTPVLYRADYPQARKRYEHRTPIVRLAPDGSIERLINNPTKMFFDGIGFDEMLPLFRAYQSLKSRLAA
TERSYLHAWSQGDMVVWDNRRIFHGRGDFGGSGFTRTLRGGYFREGELLARARFLASRAADRRAAVAS

Sequences:

>Translated_388_residues
MLTSHREHLEVAWPDGSTSRYHWVWLRQACQCASCFNRHCRQRHFDPGVVPADLRPAALSADATGLRIVWPDGHPSHYGF
DRLRDEDYDQPRRAAPADARPAWRRWPDGAPPALRFELAAALDDGALLHRALQHLFEYGLVVLKAEPTRTVEFGAVCRQL
AGFLDRSYFGEFFDLEVKADEETDSVSFSTKALPLHTDIPYCSPPPDYQFLYGLDVSSQCARDGIGSTRFVDGFTIACEL
REAQPDAFALLARTPVLYRADYPQARKRYEHRTPIVRLAPDGSIERLINNPTKMFFDGIGFDEMLPLFRAYQSLKSRLAA
TERSYLHAWSQGDMVVWDNRRIFHGRGDFGGSGFTRTLRGGYFREGELLARARFLASRAADRRAAVAS
>Mature_388_residues
MLTSHREHLEVAWPDGSTSRYHWVWLRQACQCASCFNRHCRQRHFDPGVVPADLRPAALSADATGLRIVWPDGHPSHYGF
DRLRDEDYDQPRRAAPADARPAWRRWPDGAPPALRFELAAALDDGALLHRALQHLFEYGLVVLKAEPTRTVEFGAVCRQL
AGFLDRSYFGEFFDLEVKADEETDSVSFSTKALPLHTDIPYCSPPPDYQFLYGLDVSSQCARDGIGSTRFVDGFTIACEL
REAQPDAFALLARTPVLYRADYPQARKRYEHRTPIVRLAPDGSIERLINNPTKMFFDGIGFDEMLPLFRAYQSLKSRLAA
TERSYLHAWSQGDMVVWDNRRIFHGRGDFGGSGFTRTLRGGYFREGELLARARFLASRAADRRAAVAS

Specific function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-BBH/TMLD family [H]

Homologues:

Organism=Homo sapiens, GI4502369, Length=383, Percent_Identity=25.5874673629243, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI8922625, Length=381, Percent_Identity=24.9343832020997, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI296317249, Length=280, Percent_Identity=24.2857142857143, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534641, Length=396, Percent_Identity=25.5050505050505, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24639015, Length=384, Percent_Identity=27.0833333333333, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24648401, Length=357, Percent_Identity=25.7703081232493, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221329931, Length=368, Percent_Identity=27.1739130434783, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19922166, Length=389, Percent_Identity=27.2493573264781, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012775
- InterPro:   IPR010376
- InterPro:   IPR003819 [H]

Pfam domain/function: PF06155 DUF971; PF02668 TauD [H]

EC number: =1.14.11.1 [H]

Molecular weight: Translated: 43988; Mature: 43988

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSHREHLEVAWPDGSTSRYHWVWLRQACQCASCFNRHCRQRHFDPGVVPADLRPAALS
CCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ADATGLRIVWPDGHPSHYGFDRLRDEDYDQPRRAAPADARPAWRRWPDGAPPALRFELAA
CCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHEEEEEH
ALDDGALLHRALQHLFEYGLVVLKAEPTRTVEFGAVCRQLAGFLDRSYFGEFFDLEVKAD
HCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
EETDSVSFSTKALPLHTDIPYCSPPPDYQFLYGLDVSSQCARDGIGSTRFVDGFTIACEL
CCCCCEEEEECEEEEECCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCEEECCEEEEEEE
REAQPDAFALLARTPVLYRADYPQARKRYEHRTPIVRLAPDGSIERLINNPTKMFFDGIG
CCCCCCCEEHHHCCCEEEECCCHHHHHHHHHCCCEEEECCCCHHHHHHCCCHHHHCCCCC
FDEMLPLFRAYQSLKSRLAATERSYLHAWSQGDMVVWDNRRIFHGRGDFGGSGFTRTLRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCHHHHCC
GYFREGELLARARFLASRAADRRAAVAS
CCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTSHREHLEVAWPDGSTSRYHWVWLRQACQCASCFNRHCRQRHFDPGVVPADLRPAALS
CCCCCCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ADATGLRIVWPDGHPSHYGFDRLRDEDYDQPRRAAPADARPAWRRWPDGAPPALRFELAA
CCCCCEEEECCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHEEEEEH
ALDDGALLHRALQHLFEYGLVVLKAEPTRTVEFGAVCRQLAGFLDRSYFGEFFDLEVKAD
HCCCHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
EETDSVSFSTKALPLHTDIPYCSPPPDYQFLYGLDVSSQCARDGIGSTRFVDGFTIACEL
CCCCCEEEEECEEEEECCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCEEECCEEEEEEE
REAQPDAFALLARTPVLYRADYPQARKRYEHRTPIVRLAPDGSIERLINNPTKMFFDGIG
CCCCCCCEEHHHCCCEEEECCCHHHHHHHHHCCCEEEECCCCHHHHHHCCCHHHHCCCCC
FDEMLPLFRAYQSLKSRLAATERSYLHAWSQGDMVVWDNRRIFHGRGDFGGSGFTRTLRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCCCCHHHHCC
GYFREGELLARARFLASRAADRRAAVAS
CCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8504802 [H]