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The map label for this gene is vllY [H]

Identifier: 238024554

GI number: 238024554

Start: 1473416

End: 1474543

Strand: Reverse

Name: vllY [H]

Synonym: bglu_2g11610

Alternate gene names: 238024554

Gene position: 1474543-1473416 (Counterclockwise)

Preceding gene: 238024557

Following gene: 238024553

Centisome position: 52.15

GC content: 69.06

Gene sequence:

>1128_bases
ATGTCCAGCCACTTTTCCGCGTCGTCGGCGACGACGTACCCGATCTCGCCGGACGCGAACCCGCTCGGCATCGCGGGGCT
CGAATTCGTCGAATTCGCGGCACCCGCGCCCGACGAACTGGCGCGCCGCTTCGTCCAGCTCGGCTTCAAGGCGATCGCGC
GGCACGTCAGCAAGGCAGTCACGCTGTACCGGCAAGGCCAGATGCATTTCCTGCTCAACGCCGAGCCCGATTCGTTCGCC
TCGCGCTACGCGGAGGAATACGGCATGGGCGTGTGCGCGATCGGGATTCGCGTGGACAGCGCGCCGCGCGCGTTCGACCT
CGCGCTCGAACTGGGCGCCTGGGCGTTCGAGGGCGAGCGGATCGGCCAGGGCGAGCTGGCGATCCCGGCGATCCAGGGCA
TCGGCGATTCGCACCTCTATTTCGTCGACCGCTGGCGCGGGCGCGGCGGGCTGTCGGGCGGCACCGGCGACATCTCGATC
TTCGACATCGATTTCCGGCCGATCGACCCGGCCACCGCCCAGGCCGACCTGCAGCACGTCGGCACCGGGCTGCGGCGCGT
CGATCACATGACGCAGACGGTGGGCGCCGGGCGCATGCCGGAATGGCTCGAGTTCTATCGCGACCTGCTGCACTTCCGCG
AGATCCACGAGCTGAACGCGAACTGGCACCTGTCGGACGAATCGCGCGTGATGGTGTCGCCGTGCGGCGAGATCCGCATT
CCGCTCTACGAGGAAGGCACCTCGCGCACGCAGCTGATGCACGACTACCTGCCCGATCATCCGGGCGAGGGCGTGCAGCA
CGTCGCGCTCGCCACCGACGACATCGTCGCCTGCGTGGACGCGCTCGCCGCGAACGGCGTCGAATTCGTCGAACCGCCGG
CCGCCTATTACGATTCGATCGACGCGCGGCTGCCGGAGCACCGGCTCGACGTCGAGGCGCTGCGCCGGCGCGGCATCCTG
GTGGACGGCGAGATTGTCGACGGCGTGCCGAAGCTGTTCTTCCAGACCTTCGTCAAGCGCCGGCCCGGCGAAATCTTCTT
CGAGATCGTCCAGCGCAGCGGCCATCACGGCTTCGGCGAGGGCAACCTGGGCGTGCTGGCACGGGCGCGCGAGCAGGCGC
CGCGCTGA

Upstream 100 bases:

>100_bases
CCATCGTGAACGATCTGGTTAAAATCGCGGCTGAGGCGGCACCGGCGGCGCCCGGCCGGCCGCTTCGCCACGAAACTTCG
TCTGCTTCTGGAGACTACGG

Downstream 100 bases:

>100_bases
GCGCCGGCCTTGCTGCGGGGCCGCCGGCGACGGCGCGAAACGCGGCGCTCTCCGACGAACTGCTGCGCGAGACGCTCGCC
TTGATCGACGAGCACCTGCC

Product: 4-hydroxyphenylpyruvate dioxygenase

Products: homogentisate; CO2

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSSHFSASSATTYPISPDANPLGIAGLEFVEFAAPAPDELARRFVQLGFKAIARHVSKAVTLYRQGQMHFLLNAEPDSFA
SRYAEEYGMGVCAIGIRVDSAPRAFDLALELGAWAFEGERIGQGELAIPAIQGIGDSHLYFVDRWRGRGGLSGGTGDISI
FDIDFRPIDPATAQADLQHVGTGLRRVDHMTQTVGAGRMPEWLEFYRDLLHFREIHELNANWHLSDESRVMVSPCGEIRI
PLYEEGTSRTQLMHDYLPDHPGEGVQHVALATDDIVACVDALAANGVEFVEPPAAYYDSIDARLPEHRLDVEALRRRGIL
VDGEIVDGVPKLFFQTFVKRRPGEIFFEIVQRSGHHGFGEGNLGVLARAREQAPR

Sequences:

>Translated_375_residues
MSSHFSASSATTYPISPDANPLGIAGLEFVEFAAPAPDELARRFVQLGFKAIARHVSKAVTLYRQGQMHFLLNAEPDSFA
SRYAEEYGMGVCAIGIRVDSAPRAFDLALELGAWAFEGERIGQGELAIPAIQGIGDSHLYFVDRWRGRGGLSGGTGDISI
FDIDFRPIDPATAQADLQHVGTGLRRVDHMTQTVGAGRMPEWLEFYRDLLHFREIHELNANWHLSDESRVMVSPCGEIRI
PLYEEGTSRTQLMHDYLPDHPGEGVQHVALATDDIVACVDALAANGVEFVEPPAAYYDSIDARLPEHRLDVEALRRRGIL
VDGEIVDGVPKLFFQTFVKRRPGEIFFEIVQRSGHHGFGEGNLGVLARAREQAPR
>Mature_374_residues
SSHFSASSATTYPISPDANPLGIAGLEFVEFAAPAPDELARRFVQLGFKAIARHVSKAVTLYRQGQMHFLLNAEPDSFAS
RYAEEYGMGVCAIGIRVDSAPRAFDLALELGAWAFEGERIGQGELAIPAIQGIGDSHLYFVDRWRGRGGLSGGTGDISIF
DIDFRPIDPATAQADLQHVGTGLRRVDHMTQTVGAGRMPEWLEFYRDLLHFREIHELNANWHLSDESRVMVSPCGEIRIP
LYEEGTSRTQLMHDYLPDHPGEGVQHVALATDDIVACVDALAANGVEFVEPPAAYYDSIDARLPEHRLDVEALRRRGILV
DGEIVDGVPKLFFQTFVKRRPGEIFFEIVQRSGHHGFGEGNLGVLARAREQAPR

Specific function: Unknown

COG id: COG3185

COG function: function code ER; 4-hydroxyphenylpyruvate dioxygenase and related hemolysins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 4HPPD family [H]

Homologues:

Organism=Homo sapiens, GI4504477, Length=352, Percent_Identity=25.8522727272727, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI285002264, Length=352, Percent_Identity=25.8522727272727, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI14249394, Length=243, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555220, Length=213, Percent_Identity=31.4553990610329, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17550752, Length=201, Percent_Identity=28.8557213930348, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24667510, Length=403, Percent_Identity=27.7915632754342, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21356105, Length=312, Percent_Identity=28.8461538461538, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005956
- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 1.13.11.27

Molecular weight: Translated: 41418; Mature: 41287

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHFSASSATTYPISPDANPLGIAGLEFVEFAAPAPDELARRFVQLGFKAIARHVSKAV
CCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLYRQGQMHFLLNAEPDSFASRYAEEYGMGVCAIGIRVDSAPRAFDLALELGAWAFEGER
HHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHCCEEECCCC
IGQGELAIPAIQGIGDSHLYFVDRWRGRGGLSGGTGDISIFDIDFRPIDPATAQADLQHV
CCCCCEECHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
GTGLRRVDHMTQTVGAGRMPEWLEFYRDLLHFREIHELNANWHLSDESRVMVSPCGEIRI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCEEE
PLYEEGTSRTQLMHDYLPDHPGEGVQHVALATDDIVACVDALAANGVEFVEPPAAYYDSI
EEECCCCCHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHCH
DARLPEHRLDVEALRRRGILVDGEIVDGVPKLFFQTFVKRRPGEIFFEIVQRSGHHGFGE
HHCCCHHHCCHHHHHHCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
GNLGVLARAREQAPR
CCHHHHHHHHHCCCC
>Mature Secondary Structure 
SSHFSASSATTYPISPDANPLGIAGLEFVEFAAPAPDELARRFVQLGFKAIARHVSKAV
CCCCCCCCCEECCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TLYRQGQMHFLLNAEPDSFASRYAEEYGMGVCAIGIRVDSAPRAFDLALELGAWAFEGER
HHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHCCEEECCCC
IGQGELAIPAIQGIGDSHLYFVDRWRGRGGLSGGTGDISIFDIDFRPIDPATAQADLQHV
CCCCCEECHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHH
GTGLRRVDHMTQTVGAGRMPEWLEFYRDLLHFREIHELNANWHLSDESRVMVSPCGEIRI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCEEE
PLYEEGTSRTQLMHDYLPDHPGEGVQHVALATDDIVACVDALAANGVEFVEPPAAYYDSI
EEECCCCCHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHCH
DARLPEHRLDVEALRRRGILVDGEIVDGVPKLFFQTFVKRRPGEIFFEIVQRSGHHGFGE
HHCCCHHHCCHHHHHHCCCEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCC
GNLGVLARAREQAPR
CCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxyphenylpyruvate; O2

Specific reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA