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The map label for this gene is lcfB [H]

Identifier: 238024549

GI number: 238024549

Start: 1466056

End: 1467801

Strand: Reverse

Name: lcfB [H]

Synonym: bglu_2g11550

Alternate gene names: 238024549

Gene position: 1467801-1466056 (Counterclockwise)

Preceding gene: 238024550

Following gene: 238024548

Centisome position: 51.91

GC content: 68.96

Gene sequence:

>1746_bases
ATGGAAGTTCAGGCGAAAAAGGAAGTATGGGCCAAGCTGTTCGACGACAAGGCGCTCGGCGCCGGCAATTTCCTCACCAA
GGCGCACGAGGCCTATCCGAAGCGGGACGAGATATTCCTGTTTCTGGAAAAGCCCTACGTCTCGCCGTCCGGCCAAGCGC
ATTCGTCCTTTTCGCTCGACACGCTGTATGCGGTGGTGGCCGAGCTGGCCGCCTGGTACACGCATCACGACGTGCAGCAG
GGCGCCCATGTCTGCCTCTACCTCGGCGACGGCATCGCCTCGTTCCTGCACTTCCTCGCGCTCAACAGCCTCGGCGCCGT
GCCGGTGCTGGTGAACGGCAACCTGCGCGTCGACATCGCCGTCGCCTATGCGCAGATCAACCGCTTCACGGTGTTCGCCT
ACGACCGCGAGACGGCCGCGCGCTGGCGGCTGCCGGCGCCGCTGGACGGCTTGCGCGCGCTCGACGCCGGCTTCGTCGAG
GGCAGCACCGCCCCGCAGGCGGCGCTGCCGGCCGGCGGCTGGCCGGTGGCGCGCCGCGGCGAGGACACCATCATGATCTG
CCATAGCTCGGGCACCACGGGCATCCCGAAGGCGGTGCTGTTCGGCCACGACCAGTTCTTCGCCGGCAAGCGCGAGCGCC
TGCAGGGCTTCGTCGAGCGCGACGACGACCGCCTCGCCACCGCGATGCCGACCACCCATGCCGCGGGCATCAGCTATTTG
ATGACGGGCACGCTGCTGCAACTGCCCACGCTCTCGCTGAACACTCAGCTGGGCGCCCCGGTGGCGGAAGCGATCGTCGC
GTTTCGCGCGACCATCGTCACGGCGTTCTCGCAGACCTACGCCTCGCTCGCCGAGCAGAACCTGCCGGACAACTTCCTCG
GCACCGTGCAGCGCTTCTACAACACCGGCGACACGGCGCACGAATCGCACATCCGCGAGCTGCTGCGGATTGCCCCGGAC
GCGCGCTTCACCGACATGTTCGGCGCCTCCGAACTCGGCATGTCGCAGTTCTACAAGGTTTCGCGCGCCAACGACGTGAC
CACCATTCGCACCGTCGGCTCGCCCGCGCCGTATGCGCATTGCGTGATCCTCTCGCCGGACGGCCGCGAACTCGACGACG
GCGAGCCCGGCTACTTCGGCGTGCGCTCGCCCACCGTCACGCCCGGCTACCACGGCCAGCCGCACCTGACCGCGCTCACG
CGCCTGAACGGCTACTGGCTCACGGGCGATGTGGGCCTGCGCAAGCCCAACGGCGAGTTCGTCCACCTCGACCGCATCGT
CGACGTGGTCGACACCACGCTCGGCACGCCCGGCTACACGCTGCTGCTGGAGGAACACCTGCTGCGGCTCGACTCGGTGT
TCGACGTGTCGGTGACGGGCGTCGCGCGCGGTCCGGTGCGCGAGGAGGCGGTGCTGGTGCTGGTGCGGCTCGCGGCCGGC
GCGACGCTCGAGGCCGATCAGCTGCTGCACCACGCGCTGGCCTGCCATCCGTTCCAGGGCAAGCCGAGCCTGCCCGACTA
CACGCTCTGCGTGGGCGTGATCGCGCCGCAGTTCACGCTGCCGTTGGGCTCCACCGGCAAGGTGCTCAAGCGCGTCGTGC
GCGACAGCTTCTGGTCGTGGCAGCGCGACTTCGACGGCGGCGACCGCAGCCGCTTCGTCGAGCTGCGCTGGAACCACCAG
GCCGATCTGTCCGCGCTGCCGCGCGAAGCCGAGCGCAGCCTGCTCGAACACGTGTTCGCGGCTTGA

Upstream 100 bases:

>100_bases
GGTGCGCATCGCGCGCCGTGCGGGCTTCGTTCGTCCGGACGAATGCCGATCGCAGTATCAGTTCGCTGATTCGTACATCT
CAAGAACCACGAGGGAAAAA

Downstream 100 bases:

>100_bases
GGAGGCGAGATGGACATCCTGGACACTGAACAGGTCGACGAAGCCGCATTCCAGCAGCGCATCGACGACGGCCGCAAGAT
CGAGCCGCAGGACCCCATGC

Product: putative acyl-CoA synthetase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 581; Mature: 581

Protein sequence:

>581_residues
MEVQAKKEVWAKLFDDKALGAGNFLTKAHEAYPKRDEIFLFLEKPYVSPSGQAHSSFSLDTLYAVVAELAAWYTHHDVQQ
GAHVCLYLGDGIASFLHFLALNSLGAVPVLVNGNLRVDIAVAYAQINRFTVFAYDRETAARWRLPAPLDGLRALDAGFVE
GSTAPQAALPAGGWPVARRGEDTIMICHSSGTTGIPKAVLFGHDQFFAGKRERLQGFVERDDDRLATAMPTTHAAGISYL
MTGTLLQLPTLSLNTQLGAPVAEAIVAFRATIVTAFSQTYASLAEQNLPDNFLGTVQRFYNTGDTAHESHIRELLRIAPD
ARFTDMFGASELGMSQFYKVSRANDVTTIRTVGSPAPYAHCVILSPDGRELDDGEPGYFGVRSPTVTPGYHGQPHLTALT
RLNGYWLTGDVGLRKPNGEFVHLDRIVDVVDTTLGTPGYTLLLEEHLLRLDSVFDVSVTGVARGPVREEAVLVLVRLAAG
ATLEADQLLHHALACHPFQGKPSLPDYTLCVGVIAPQFTLPLGSTGKVLKRVVRDSFWSWQRDFDGGDRSRFVELRWNHQ
ADLSALPREAERSLLEHVFAA

Sequences:

>Translated_581_residues
MEVQAKKEVWAKLFDDKALGAGNFLTKAHEAYPKRDEIFLFLEKPYVSPSGQAHSSFSLDTLYAVVAELAAWYTHHDVQQ
GAHVCLYLGDGIASFLHFLALNSLGAVPVLVNGNLRVDIAVAYAQINRFTVFAYDRETAARWRLPAPLDGLRALDAGFVE
GSTAPQAALPAGGWPVARRGEDTIMICHSSGTTGIPKAVLFGHDQFFAGKRERLQGFVERDDDRLATAMPTTHAAGISYL
MTGTLLQLPTLSLNTQLGAPVAEAIVAFRATIVTAFSQTYASLAEQNLPDNFLGTVQRFYNTGDTAHESHIRELLRIAPD
ARFTDMFGASELGMSQFYKVSRANDVTTIRTVGSPAPYAHCVILSPDGRELDDGEPGYFGVRSPTVTPGYHGQPHLTALT
RLNGYWLTGDVGLRKPNGEFVHLDRIVDVVDTTLGTPGYTLLLEEHLLRLDSVFDVSVTGVARGPVREEAVLVLVRLAAG
ATLEADQLLHHALACHPFQGKPSLPDYTLCVGVIAPQFTLPLGSTGKVLKRVVRDSFWSWQRDFDGGDRSRFVELRWNHQ
ADLSALPREAERSLLEHVFAA
>Mature_581_residues
MEVQAKKEVWAKLFDDKALGAGNFLTKAHEAYPKRDEIFLFLEKPYVSPSGQAHSSFSLDTLYAVVAELAAWYTHHDVQQ
GAHVCLYLGDGIASFLHFLALNSLGAVPVLVNGNLRVDIAVAYAQINRFTVFAYDRETAARWRLPAPLDGLRALDAGFVE
GSTAPQAALPAGGWPVARRGEDTIMICHSSGTTGIPKAVLFGHDQFFAGKRERLQGFVERDDDRLATAMPTTHAAGISYL
MTGTLLQLPTLSLNTQLGAPVAEAIVAFRATIVTAFSQTYASLAEQNLPDNFLGTVQRFYNTGDTAHESHIRELLRIAPD
ARFTDMFGASELGMSQFYKVSRANDVTTIRTVGSPAPYAHCVILSPDGRELDDGEPGYFGVRSPTVTPGYHGQPHLTALT
RLNGYWLTGDVGLRKPNGEFVHLDRIVDVVDTTLGTPGYTLLLEEHLLRLDSVFDVSVTGVARGPVREEAVLVLVRLAAG
ATLEADQLLHHALACHPFQGKPSLPDYTLCVGVIAPQFTLPLGSTGKVLKRVVRDSFWSWQRDFDGGDRSRFVELRWNHQ
ADLSALPREAERSLLEHVFAA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17559526, Length=410, Percent_Identity=24.8780487804878, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581924, Length=382, Percent_Identity=24.3455497382199, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653035, Length=375, Percent_Identity=24.2666666666667, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020459
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 63562; Mature: 63562

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVQAKKEVWAKLFDDKALGAGNFLTKAHEAYPKRDEIFLFLEKPYVSPSGQAHSSFSLD
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHH
TLYAVVAELAAWYTHHDVQQGAHVCLYLGDGIASFLHFLALNSLGAVPVLVNGNLRVDIA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCEEEEEE
VAYAQINRFTVFAYDRETAARWRLPAPLDGLRALDAGFVEGSTAPQAALPAGGWPVARRG
EEEEECCEEEEEEECCCCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
EDTIMICHSSGTTGIPKAVLFGHDQFFAGKRERLQGFVERDDDRLATAMPTTHAAGISYL
CCEEEEEECCCCCCCCCCEEECCHHHHCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHHH
MTGTLLQLPTLSLNTQLGAPVAEAIVAFRATIVTAFSQTYASLAEQNLPDNFLGTVQRFY
HHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTGDTAHESHIRELLRIAPDARFTDMFGASELGMSQFYKVSRANDVTTIRTVGSPAPYAH
CCCCCHHHHHHHHHHHHCCCCCHHHHCCCHHHCHHHHHHHHCCCCCEEEEECCCCCCCEE
CVILSPDGRELDDGEPGYFGVRSPTVTPGYHGQPHLTALTRLNGYWLTGDVGLRKPNGEF
EEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHEEECCCEEEECCCCEECCCCCE
VHLDRIVDVVDTTLGTPGYTLLLEEHLLRLDSVFDVSVTGVARGPVREEAVLVLVRLAAG
EEHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCEEEEEEECEECCCCHHHHHHHHHHHHCC
ATLEADQLLHHALACHPFQGKPSLPDYTLCVGVIAPQFTLPLGSTGKVLKRVVRDSFWSW
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHH
QRDFDGGDRSRFVELRWNHQADLSALPREAERSLLEHVFAA
HCCCCCCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEVQAKKEVWAKLFDDKALGAGNFLTKAHEAYPKRDEIFLFLEKPYVSPSGQAHSSFSLD
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHH
TLYAVVAELAAWYTHHDVQQGAHVCLYLGDGIASFLHFLALNSLGAVPVLVNGNLRVDIA
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCEEEEEE
VAYAQINRFTVFAYDRETAARWRLPAPLDGLRALDAGFVEGSTAPQAALPAGGWPVARRG
EEEEECCEEEEEEECCCCHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
EDTIMICHSSGTTGIPKAVLFGHDQFFAGKRERLQGFVERDDDRLATAMPTTHAAGISYL
CCEEEEEECCCCCCCCCCEEECCHHHHCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHHH
MTGTLLQLPTLSLNTQLGAPVAEAIVAFRATIVTAFSQTYASLAEQNLPDNFLGTVQRFY
HHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
NTGDTAHESHIRELLRIAPDARFTDMFGASELGMSQFYKVSRANDVTTIRTVGSPAPYAH
CCCCCHHHHHHHHHHHHCCCCCHHHHCCCHHHCHHHHHHHHCCCCCEEEEECCCCCCCEE
CVILSPDGRELDDGEPGYFGVRSPTVTPGYHGQPHLTALTRLNGYWLTGDVGLRKPNGEF
EEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHEEECCCEEEECCCCEECCCCCE
VHLDRIVDVVDTTLGTPGYTLLLEEHLLRLDSVFDVSVTGVARGPVREEAVLVLVRLAAG
EEHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCEEEEEEECEECCCCHHHHHHHHHHHHCC
ATLEADQLLHHALACHPFQGKPSLPDYTLCVGVIAPQFTLPLGSTGKVLKRVVRDSFWSW
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHH
QRDFDGGDRSRFVELRWNHQADLSALPREAERSLLEHVFAA
HCCCCCCCCCEEEEEEECCCCCHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]