Click here to switch to the map view.

The map label for this gene is trpE [H]

Identifier: 238024539

GI number: 238024539

Start: 1455766

End: 1457310

Strand: Reverse

Name: trpE [H]

Synonym: bglu_2g11450

Alternate gene names: 238024539

Gene position: 1457310-1455766 (Counterclockwise)

Preceding gene: 238024540

Following gene: 238024538

Centisome position: 51.54

GC content: 70.68

Gene sequence:

>1545_bases
ATGTTGAGCCAGGATGAGTTTACGCGGTACGGCGAGGCGGGGTTCAACCTCGTGCCGCTCTGGAAGGTGCTGCCGCTGCC
CGAGCGGCTCGATCCGCTGGACGTCTATCGCGCGCTCGCGAACCGGCGCGACGACTACCTGTTCGAGACCGGCGAGTGGG
AGAACGCGGCGTTTACGCGCCACTACTCGACCATCGGCCTGCCCTGCGGCGAGCGCATCGAGCTGGACGAGGATGCGATC
CGCCATCTGCGCCACGGCCGCGTGCAGAGCGAGCAGCGCACCGACGATCCGCTCGCCGCGCTGCGCCGCCTGCAGGAAGG
CTTTCGCGTGCCGCACTTCGACAGCCTGCCGCCGTTCTCGGGCGGCCTGTTCGGCTACTTCGGCTTCGAGACCACGCGTC
TGATCGAGCCGCGCCTGCGCCGCACGGCGCGCAAGCCCTCGGGCCTGCAGGTCCCCGACGTGGTGCAGCTGGTGAGCCGC
GAGCTGGTGGTGATCGACCATCGCCGCCGCCAGCTGTTCTGCATCGTTCACGAGGATCCGTCCGAGGCCGGCAGCCACGC
GCGCGGCCTGGCACGGCTGGAGGCGATGGCCGCGCAGTTGGGCGCGATCGCCCCGGCGCGCGCGCGCGAGCCCGGCACCA
CCCGGGGCCTCGCCGTCGACGCGAGCCGGCTGTCGTTCGGCTTCGCGCGCGAAGCCTACGAAGGCGCCGTCGACCGCATC
AAGGACTACATCGCCGCCGGCGAAGTGATGCAGGTGGTGCTCGCGCAGCGCATGAGCCGCCCGCTCGCCTGCGATGCCAT
CGCGCTCTACCGCGCGCTCGGCGATCTCGCGCAGACGCCGTACCGCTACCTGGTCAACCTCGGCGAATGCGCGATCGTGG
GCGCCTCGCCCGAGATGCTGGTGCAGCAGCGCGGCGACATCGTCACGAGCCGTCCGATGGCCGGCACGCGCCGCCGCACC
CAGGACGATGCCGAGGACGCGCGCCTGAAGCAGGAACTGCTGGCCGATCCGAAGGAGATCGCCGAGCACATGATGCTGGT
CGATCTCGCGCGCAACGACGTGGGCCGTCTGGCCGTGCCCGGCGGCGTGCAGGTGGACGAGCTGCTGACGGTCGAATATT
TCTCGCACGTCATGCACATCGTCTCGACCGTCACCGGCAAGCTGCCCGGGCAGGTCCACGGGATCGACGTGCTGCGCAGC
ACGTTCCCGGCCGGCACGCTGAGCGGCGCCTCGAAGGTGCGTGCGCTGGAAGTGATCGCCGAGCTCGAGCCGCACTCGCG
CGGCATCTACGGCGGCGCGGTCGGCTATCTCGACTGGCGCGGCCAGGCCGAGCTGGCCATCACGATTCGCACCGGCGTGC
TGCAGGGCGGGCTGCTGCACGTGCAGTCGGGCGCCGGCGTGGTGAAGGACTCGGTGGCCGAGCGCGAGTGGCAGGAAACC
ATGGACAAGAGCCGCATGATGCTGCTGGCGGCCGAGCTGGCGGAACGCCAGAGCGAAACGGCGCGCTCCGGCGCGGCGCA
ACAGGAGGCAACGGCATGCATCTGA

Upstream 100 bases:

>100_bases
CGCTCACGCCGAACGGCAAGCCCAACCGCCGCGCGCTCGCCCAGCTGGCGAGCCGCGCGCTGCAAGACGGGACGGGCATC
AATCTAGTGGAGGAATCAAC

Downstream 100 bases:

>100_bases
TGATCGACAACTACGACTCGTTCACCTACAACGTGGTCCAGTATCTCTGCACGCTCGGCGCGCAGGTCGAGGTGAGGCGC
AACGACCAGATCACGGTGGA

Product: Anthranilate synthase component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MLSQDEFTRYGEAGFNLVPLWKVLPLPERLDPLDVYRALANRRDDYLFETGEWENAAFTRHYSTIGLPCGERIELDEDAI
RHLRHGRVQSEQRTDDPLAALRRLQEGFRVPHFDSLPPFSGGLFGYFGFETTRLIEPRLRRTARKPSGLQVPDVVQLVSR
ELVVIDHRRRQLFCIVHEDPSEAGSHARGLARLEAMAAQLGAIAPARAREPGTTRGLAVDASRLSFGFAREAYEGAVDRI
KDYIAAGEVMQVVLAQRMSRPLACDAIALYRALGDLAQTPYRYLVNLGECAIVGASPEMLVQQRGDIVTSRPMAGTRRRT
QDDAEDARLKQELLADPKEIAEHMMLVDLARNDVGRLAVPGGVQVDELLTVEYFSHVMHIVSTVTGKLPGQVHGIDVLRS
TFPAGTLSGASKVRALEVIAELEPHSRGIYGGAVGYLDWRGQAELAITIRTGVLQGGLLHVQSGAGVVKDSVAEREWQET
MDKSRMMLLAAELAERQSETARSGAAQQEATACI

Sequences:

>Translated_514_residues
MLSQDEFTRYGEAGFNLVPLWKVLPLPERLDPLDVYRALANRRDDYLFETGEWENAAFTRHYSTIGLPCGERIELDEDAI
RHLRHGRVQSEQRTDDPLAALRRLQEGFRVPHFDSLPPFSGGLFGYFGFETTRLIEPRLRRTARKPSGLQVPDVVQLVSR
ELVVIDHRRRQLFCIVHEDPSEAGSHARGLARLEAMAAQLGAIAPARAREPGTTRGLAVDASRLSFGFAREAYEGAVDRI
KDYIAAGEVMQVVLAQRMSRPLACDAIALYRALGDLAQTPYRYLVNLGECAIVGASPEMLVQQRGDIVTSRPMAGTRRRT
QDDAEDARLKQELLADPKEIAEHMMLVDLARNDVGRLAVPGGVQVDELLTVEYFSHVMHIVSTVTGKLPGQVHGIDVLRS
TFPAGTLSGASKVRALEVIAELEPHSRGIYGGAVGYLDWRGQAELAITIRTGVLQGGLLHVQSGAGVVKDSVAEREWQET
MDKSRMMLLAAELAERQSETARSGAAQQEATACI
>Mature_514_residues
MLSQDEFTRYGEAGFNLVPLWKVLPLPERLDPLDVYRALANRRDDYLFETGEWENAAFTRHYSTIGLPCGERIELDEDAI
RHLRHGRVQSEQRTDDPLAALRRLQEGFRVPHFDSLPPFSGGLFGYFGFETTRLIEPRLRRTARKPSGLQVPDVVQLVSR
ELVVIDHRRRQLFCIVHEDPSEAGSHARGLARLEAMAAQLGAIAPARAREPGTTRGLAVDASRLSFGFAREAYEGAVDRI
KDYIAAGEVMQVVLAQRMSRPLACDAIALYRALGDLAQTPYRYLVNLGECAIVGASPEMLVQQRGDIVTSRPMAGTRRRT
QDDAEDARLKQELLADPKEIAEHMMLVDLARNDVGRLAVPGGVQVDELLTVEYFSHVMHIVSTVTGKLPGQVHGIDVLRS
TFPAGTLSGASKVRALEVIAELEPHSRGIYGGAVGYLDWRGQAELAITIRTGVLQGGLLHVQSGAGVVKDSVAEREWQET
MDKSRMMLLAAELAERQSETARSGAAQQEATACI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=405, Percent_Identity=34.5679012345679, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI1787518, Length=421, Percent_Identity=36.104513064133, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1786809, Length=265, Percent_Identity=32.4528301886792, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87082077, Length=277, Percent_Identity=25.9927797833935, Blast_Score=89, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320935, Length=481, Percent_Identity=32.8482328482328, Blast_Score=240, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6324361, Length=383, Percent_Identity=24.5430809399478, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 56749; Mature: 56749

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSQDEFTRYGEAGFNLVPLWKVLPLPERLDPLDVYRALANRRDDYLFETGEWENAAFTR
CCCHHHHHHHCCCCCCEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCHHE
HYSTIGLPCGERIELDEDAIRHLRHGRVQSEQRTDDPLAALRRLQEGFRVPHFDSLPPFS
ECCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GGLFGYFGFETTRLIEPRLRRTARKPSGLQVPDVVQLVSRELVVIDHRRRQLFCIVHEDP
CCCEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCCCEEEEEEECCH
SEAGSHARGLARLEAMAAQLGAIAPARAREPGTTRGLAVDASRLSFGFAREAYEGAVDRI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
KDYIAAGEVMQVVLAQRMSRPLACDAIALYRALGDLAQTPYRYLVNLGECAIVGASPEML
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEECCCHHHH
VQQRGDIVTSRPMAGTRRRTQDDAEDARLKQELLADPKEIAEHMMLVDLARNDVGRLAVP
HHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECC
GGVQVDELLTVEYFSHVMHIVSTVTGKLPGQVHGIDVLRSTFPAGTLSGASKVRALEVIA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ELEPHSRGIYGGAVGYLDWRGQAELAITIRTGVLQGGLLHVQSGAGVVKDSVAEREWQET
HCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHH
MDKSRMMLLAAELAERQSETARSGAAQQEATACI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure
MLSQDEFTRYGEAGFNLVPLWKVLPLPERLDPLDVYRALANRRDDYLFETGEWENAAFTR
CCCHHHHHHHCCCCCCEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCCHHE
HYSTIGLPCGERIELDEDAIRHLRHGRVQSEQRTDDPLAALRRLQEGFRVPHFDSLPPFS
ECCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GGLFGYFGFETTRLIEPRLRRTARKPSGLQVPDVVQLVSRELVVIDHRRRQLFCIVHEDP
CCCEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEECCCCEEEEEEECCH
SEAGSHARGLARLEAMAAQLGAIAPARAREPGTTRGLAVDASRLSFGFAREAYEGAVDRI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
KDYIAAGEVMQVVLAQRMSRPLACDAIALYRALGDLAQTPYRYLVNLGECAIVGASPEML
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEECCCHHHH
VQQRGDIVTSRPMAGTRRRTQDDAEDARLKQELLADPKEIAEHMMLVDLARNDVGRLAVP
HHHCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECC
GGVQVDELLTVEYFSHVMHIVSTVTGKLPGQVHGIDVLRSTFPAGTLSGASKVRALEVIA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ELEPHSRGIYGGAVGYLDWRGQAELAITIRTGVLQGGLLHVQSGAGVVKDSVAEREWQET
HCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHH
MDKSRMMLLAAELAERQSETARSGAAQQEATACI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043; 8444788 [H]