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The map label for this gene is fur [H]

Identifier: 238024419

GI number: 238024419

Start: 1290399

End: 1290842

Strand: Direct

Name: fur [H]

Synonym: bglu_2g10120

Alternate gene names: 238024419

Gene position: 1290399-1290842 (Clockwise)

Preceding gene: 238024417

Following gene: 238024420

Centisome position: 45.64

GC content: 66.67

Gene sequence:

>444_bases
ATGCCAGTCCATGAGCAGTTGCAGGGTGCGGGATTGCGCGCGACGTTGCCGCGCGTGAAGGTGCTGGAGTTCTTCGCGGC
GGCGCGTCCGCGGCACGTCAGTGCCGAGGACGTGTTTCGCCATCTGCTGGCCGAGAAGATCGACATCGGTCTCGCCACGG
TCTACCGGGTGCTCTCGCAGTTCGTCGAGGCGGGAATCCTGACGAGCGGCACGCTCGATTCGAACCGCCACGTCTACGAG
CTCAACGACGGCAAGCGGCACGATCACATCATCTGCCTGGCTTGCGGCAAGGTGGACGAGTTCTCCGATCCGCTGATCGA
CGGCCGTGAGAAGGCGGCCGCCGATGCGCTCGGCTATCTGCTGACGGGCCACCATCTGGTGCTGCATGGCTACTGCGCCG
AATGCCGGCCGAAGCCGCGCGGGGCCGACCCCGACGGCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCGGGTACTCGGGCCGAGGCGCGCGGCGGCGGGGCGGCGAGATCGGTCGCGGCGGGCCGCCCGGGCCGGCCCGTCCA
TTGTCGACTCGTCTATGCTG

Downstream 100 bases:

>100_bases
TTCTTCCGAGTCCGTCCGAATCCGCCCGGCTCGCCCCGGGCGCGGCGCGCTGCCGAACGCGGGGCCTTCGGCAGCGCCGC
CATCCCATTCCAATAACGAT

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MPVHEQLQGAGLRATLPRVKVLEFFAAARPRHVSAEDVFRHLLAEKIDIGLATVYRVLSQFVEAGILTSGTLDSNRHVYE
LNDGKRHDHIICLACGKVDEFSDPLIDGREKAAADALGYLLTGHHLVLHGYCAECRPKPRGADPDGA

Sequences:

>Translated_147_residues
MPVHEQLQGAGLRATLPRVKVLEFFAAARPRHVSAEDVFRHLLAEKIDIGLATVYRVLSQFVEAGILTSGTLDSNRHVYE
LNDGKRHDHIICLACGKVDEFSDPLIDGREKAAADALGYLLTGHHLVLHGYCAECRPKPRGADPDGA
>Mature_146_residues
PVHEQLQGAGLRATLPRVKVLEFFAAARPRHVSAEDVFRHLLAEKIDIGLATVYRVLSQFVEAGILTSGTLDSNRHVYEL
NDGKRHDHIICLACGKVDEFSDPLIDGREKAAADALGYLLTGHHLVLHGYCAECRPKPRGADPDGA

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=49.6240601503759, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16090; Mature: 15958

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVHEQLQGAGLRATLPRVKVLEFFAAARPRHVSAEDVFRHLLAEKIDIGLATVYRVLSQ
CCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FVEAGILTSGTLDSNRHVYELNDGKRHDHIICLACGKVDEFSDPLIDGREKAAADALGYL
HHHHCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LTGHHLVLHGYCAECRPKPRGADPDGA
HHCCCCEEEEEHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PVHEQLQGAGLRATLPRVKVLEFFAAARPRHVSAEDVFRHLLAEKIDIGLATVYRVLSQ
CCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
FVEAGILTSGTLDSNRHVYELNDGKRHDHIICLACGKVDEFSDPLIDGREKAAADALGYL
HHHHCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LTGHHLVLHGYCAECRPKPRGADPDGA
HHCCCCEEEEEHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]