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The map label for this gene is lgrD [H]

Identifier: 238024399

GI number: 238024399

Start: 1260114

End: 1263371

Strand: Reverse

Name: lgrD [H]

Synonym: bglu_2g09920

Alternate gene names: 238024399

Gene position: 1263371-1260114 (Counterclockwise)

Preceding gene: 339717970

Following gene: 238024398

Centisome position: 44.68

GC content: 70.44

Gene sequence:

>3258_bases
ATGTCCACGACTCCGCTCTCCGCATATCAGTACCGCTTCTGGCTCGAATGGCGACTCGCACCGCATTCGGCCGCCTACAC
CACCGCGCTCGTCTACCGCCTGATCGGGCCGCTCCGTCGCGACGCCCTGCAGCAGGCGCTCGAGGCCTTCGTTCACGAGC
ACGACGAAGGCTGCCGCAGCGTGTTCCGCGACGACGGCGGCGATCCCGTGCGGATCGTCCATCCGCGTATCGAGGTCGAT
CTCGAGTATCGCGACGCGCGTGGTGACGGTCCCGCCCAGCCGGCGCTCGACGCGGCCGCACGCGACGCATGGATTGCCGA
GCGCGCCGCCACCGTGTTCGCGCTCGACCGCGCGCCGCTGTTCCGTTTCTCGCTGCTGCGCGAGGACGACGCCACGCATC
GTCTGGTGCTGGCCTTCCCTCACATCATTTCCGACGCGTTCTCGGCGCGCTACATCAATGCGCGCCTGAGCGCGCTGTAC
AACCACGCGCTCGGCGCGGGCCCGGCGCCGGATCGCACGCATCGGGATCTCGACGGCTTTCTCGCGCTCGAGGCCGAGTA
TCGCGCCTCGGGCGCCCGGCAGGCCGATCTCGACTACTGGCTCGCGCTGCTGGGCGAGGCGCCGCTCGGCGTCGATCTGC
CTGCCCCGGAAACGGCCGAGGCTGGCGCCCGCGATTGCATTCATCGGATGCATTTCGATGCCACCGTCGCGCAGGCCCTG
AAGGCGTGTGCCAAGGCCAACCGCTCGACGCCGTTCCTGCTGCTCTCGAGCCTGTTCGCGATCGCGCTGGCGCGCTGGCT
GGACCTGCCGGAGCTGGTGCTGTCCTACCCCGTCAACCTGCGCTCGCCGGGCTTCGAGCAAACCAGCGGCTGCTTCGTCA
ACAACCTGCCGATGCCTATCGCGCTGCGGGACGACGACAGCTTCCGCGACGTGTTCGCGCGCACAACCGCCCAGCGCGCC
GCGAGCCGGCGCCGCCAACGCCTTGCGCTGACCGACCTGGTCGCGGCGCTGCGCCGCCGCCGCACGCTCGCCGACGAGCC
GATATTCAACGTCGGCATCACCGAGGCGTTCTTCACCCAGTCCTCACCGCTCGATTTCCGGCAAGTAGCCTCCGAATTGC
TGCCGGCGGCGGCAACCGAGCGACCGCTCGATCTGAACTTCGCTTATCAGCTCACGCCCGACGGACTCCACGTCAACCTC
GAGCACGACACGCGCCATCTGTCGCCGGCACGCATCGCGGCCTTTGCGGCCCGCTTCGAACGCCTGTTGGCAGCCTGCCT
CGCCGATGACACGCAGGCCGTGCATGCCGTGGCGCTGCTCGGTGCGGAGGAACGCGAGCGGCTCTCGCGTTTCTGGCACG
GCCCGGCGCGCGCGCTCGACGACAGCCATTGGTACGCCCGCTTCGCCGCGCAATGCGCCGCCAGCCCCGACGCGATCGCC
GTCGAGGCCGGCGAGACCCGGCTGAGCTACCGCGAGCTGGACGCGTCGAGCGCACGGCTGGCCGGCGCGCTGGCCGCGCG
CGGCGTCGTGGCGGGCAGCCGCGTGGGCCTCTGCTGCGAGCGCTCGCCGGAGATGGTGCTCGCCATCGTCGCCGTGCTGC
GCTGCGGCGCCGCCTACATCCCGCTCGATCCGGAAGCGCCGCCCGAGCGCGTATCGCGCATCGTCGCCGACGCCAGCCCC
GTGCTGCTACTGACGCAGCGCCGGCTCGCCCCACGCTTGCCTGCGGCCACCGTACCGCAGCTGTTGCTCGACGACGCGGC
CTGGCGCGAGGCCGCACCGCTGCCGCCGCAAGCGATCCCGCCCGAGGCGATCGCCTACGTGATCTATACCTCCGGCTCGA
CCGGCATGCCCAAGGGCGTCGCCAACACGCATCGCGCACTGCTCAACCGGCTCGACTGGCAGAACACGCTGCTGCGCGGC
GGCATCACCGCGCGCACGTTGCAGAAGACCCCCTATACGTTCGACGTGTCGGTCTGGGAACTGCTCTGGCCCCTGCTAAA
CGGCGCCGCGCTGGTGGTCGCGCCGCCGGGCCTGCACCGCGATCCGACCGGGCTCGCCAGCCTGATGCGCGAGGCCGGGG
TGGCAGTCGCGCACTTCGTGCCCTCGATGCTGAACGCCTTTCTCGACGTCATGCCGGGCCGGCAGTTGCCCGATCTCGCG
CTGGTCATCTGCAGCGGCGAGGCCCTGCTCGCAGAGCAGGCCGAGCGCTTCCGGCGCCTGCTGCCCGGCACGCGGCTGGT
CAACCTGTACGGACCGACCGAGGCCGCCATTGACGTCAGTGCCTGGCCCTGCGAGAGCGCCACGCCGGCAGGACGCGCCG
GCATACCGATCGGCCGGCCGATCGACAACGTCTCGCTGTACGTGCTGGACTCGCGGCTCTCGCCCTGCCCGCCCGGCCAG
CGCGGCGAACTGTACATCGGCGGCGCGGCGCTGGCGGCGGGCTATCTGGGCCGTCCCGACCTAACCGCCGCCAGTTTCGT
GCCGGACCCGCTCAGCGACCGCCCCGGCGCCCGCATGTACCGCACCGGCGACATCGCCATGTTCGGAGAGCACGGCGAAC
TGCACTATCTCGGCCGCCGCGACGAGCAGGTCAAACTCAACGGCAACCGCATCGAGCTGCGCGAGATCGAGGCTTGCCTG
CTCGCGCTGCCAGGCGTCGCGCAGTGTGCCGTGGTGCCGGTTGCCGTCAACGGCCGCATCAGGCATCTGCACGGCTTCGT
CGAACCGGCCGCCGGCGGGCAGCGCTGGGCCGAGGGCGAACTCGAGGACTGGCTCGCGAGCCGCCTGCCCGAGGTCATGC
GGCCCGCGCGCATCGAGGTGGTGGAGCGCATCGCGCTGCTAACGGCCGGCAAGATCGACCGCAAGCGGCTGCGCCAGCAA
GCCCAGGCCGCACTCGAGCGCACCGCGTCGACCTCGCTCGCACGCCCCAAGACTGCATTCCAGCGCGATATCGCCACCGA
GTGGTCGGCCGTGCTGGAAACCGGCGAGATCGGCGCGGACGAAAACTTCTTCATGCTGGGCGGCAGCTCGGTGCAGGCGA
TCCAACTGATTGGCCGGCTCAACCGCCGCTTCGGCCTGCTTCTGACGCCGGCCATGCTGTTCAACGCGCCGCAGCTCGAC
CGATTCAGTGCTCAGGTGCTGGCCGAACTGGGGCGGCATGCACAGCGCGAGGGAACGCTCGCCGCACTGCTCGACGGCCT
CGGCCCCGAGGACATGGACGAATTACTCAAATTGTTTGAAGCGAGGGAGCTGGCTTGA

Upstream 100 bases:

>100_bases
TTCGCCACGGCGAAGCCATCGGCCGCCTCCATGCAATGACGCCAGCGGCACCGCGGCCCGATCCGCCGCCCGCCATTCCC
GAATCCCGATTGCGCCAATC

Downstream 100 bases:

>100_bases
TGTCTAACAAGGAATCCATCGAAAACAAGCGCCGCAAGCTGCTCGAGGCGTTCAGCAAGCAAGACGGCGGCGCGGCGCGC
GAAGCGATCACGCGCCGGCC

Product: Non-ribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1085; Mature: 1084

Protein sequence:

>1085_residues
MSTTPLSAYQYRFWLEWRLAPHSAAYTTALVYRLIGPLRRDALQQALEAFVHEHDEGCRSVFRDDGGDPVRIVHPRIEVD
LEYRDARGDGPAQPALDAAARDAWIAERAATVFALDRAPLFRFSLLREDDATHRLVLAFPHIISDAFSARYINARLSALY
NHALGAGPAPDRTHRDLDGFLALEAEYRASGARQADLDYWLALLGEAPLGVDLPAPETAEAGARDCIHRMHFDATVAQAL
KACAKANRSTPFLLLSSLFAIALARWLDLPELVLSYPVNLRSPGFEQTSGCFVNNLPMPIALRDDDSFRDVFARTTAQRA
ASRRRQRLALTDLVAALRRRRTLADEPIFNVGITEAFFTQSSPLDFRQVASELLPAAATERPLDLNFAYQLTPDGLHVNL
EHDTRHLSPARIAAFAARFERLLAACLADDTQAVHAVALLGAEERERLSRFWHGPARALDDSHWYARFAAQCAASPDAIA
VEAGETRLSYRELDASSARLAGALAARGVVAGSRVGLCCERSPEMVLAIVAVLRCGAAYIPLDPEAPPERVSRIVADASP
VLLLTQRRLAPRLPAATVPQLLLDDAAWREAAPLPPQAIPPEAIAYVIYTSGSTGMPKGVANTHRALLNRLDWQNTLLRG
GITARTLQKTPYTFDVSVWELLWPLLNGAALVVAPPGLHRDPTGLASLMREAGVAVAHFVPSMLNAFLDVMPGRQLPDLA
LVICSGEALLAEQAERFRRLLPGTRLVNLYGPTEAAIDVSAWPCESATPAGRAGIPIGRPIDNVSLYVLDSRLSPCPPGQ
RGELYIGGAALAAGYLGRPDLTAASFVPDPLSDRPGARMYRTGDIAMFGEHGELHYLGRRDEQVKLNGNRIELREIEACL
LALPGVAQCAVVPVAVNGRIRHLHGFVEPAAGGQRWAEGELEDWLASRLPEVMRPARIEVVERIALLTAGKIDRKRLRQQ
AQAALERTASTSLARPKTAFQRDIATEWSAVLETGEIGADENFFMLGGSSVQAIQLIGRLNRRFGLLLTPAMLFNAPQLD
RFSAQVLAELGRHAQREGTLAALLDGLGPEDMDELLKLFEARELA

Sequences:

>Translated_1085_residues
MSTTPLSAYQYRFWLEWRLAPHSAAYTTALVYRLIGPLRRDALQQALEAFVHEHDEGCRSVFRDDGGDPVRIVHPRIEVD
LEYRDARGDGPAQPALDAAARDAWIAERAATVFALDRAPLFRFSLLREDDATHRLVLAFPHIISDAFSARYINARLSALY
NHALGAGPAPDRTHRDLDGFLALEAEYRASGARQADLDYWLALLGEAPLGVDLPAPETAEAGARDCIHRMHFDATVAQAL
KACAKANRSTPFLLLSSLFAIALARWLDLPELVLSYPVNLRSPGFEQTSGCFVNNLPMPIALRDDDSFRDVFARTTAQRA
ASRRRQRLALTDLVAALRRRRTLADEPIFNVGITEAFFTQSSPLDFRQVASELLPAAATERPLDLNFAYQLTPDGLHVNL
EHDTRHLSPARIAAFAARFERLLAACLADDTQAVHAVALLGAEERERLSRFWHGPARALDDSHWYARFAAQCAASPDAIA
VEAGETRLSYRELDASSARLAGALAARGVVAGSRVGLCCERSPEMVLAIVAVLRCGAAYIPLDPEAPPERVSRIVADASP
VLLLTQRRLAPRLPAATVPQLLLDDAAWREAAPLPPQAIPPEAIAYVIYTSGSTGMPKGVANTHRALLNRLDWQNTLLRG
GITARTLQKTPYTFDVSVWELLWPLLNGAALVVAPPGLHRDPTGLASLMREAGVAVAHFVPSMLNAFLDVMPGRQLPDLA
LVICSGEALLAEQAERFRRLLPGTRLVNLYGPTEAAIDVSAWPCESATPAGRAGIPIGRPIDNVSLYVLDSRLSPCPPGQ
RGELYIGGAALAAGYLGRPDLTAASFVPDPLSDRPGARMYRTGDIAMFGEHGELHYLGRRDEQVKLNGNRIELREIEACL
LALPGVAQCAVVPVAVNGRIRHLHGFVEPAAGGQRWAEGELEDWLASRLPEVMRPARIEVVERIALLTAGKIDRKRLRQQ
AQAALERTASTSLARPKTAFQRDIATEWSAVLETGEIGADENFFMLGGSSVQAIQLIGRLNRRFGLLLTPAMLFNAPQLD
RFSAQVLAELGRHAQREGTLAALLDGLGPEDMDELLKLFEARELA
>Mature_1084_residues
STTPLSAYQYRFWLEWRLAPHSAAYTTALVYRLIGPLRRDALQQALEAFVHEHDEGCRSVFRDDGGDPVRIVHPRIEVDL
EYRDARGDGPAQPALDAAARDAWIAERAATVFALDRAPLFRFSLLREDDATHRLVLAFPHIISDAFSARYINARLSALYN
HALGAGPAPDRTHRDLDGFLALEAEYRASGARQADLDYWLALLGEAPLGVDLPAPETAEAGARDCIHRMHFDATVAQALK
ACAKANRSTPFLLLSSLFAIALARWLDLPELVLSYPVNLRSPGFEQTSGCFVNNLPMPIALRDDDSFRDVFARTTAQRAA
SRRRQRLALTDLVAALRRRRTLADEPIFNVGITEAFFTQSSPLDFRQVASELLPAAATERPLDLNFAYQLTPDGLHVNLE
HDTRHLSPARIAAFAARFERLLAACLADDTQAVHAVALLGAEERERLSRFWHGPARALDDSHWYARFAAQCAASPDAIAV
EAGETRLSYRELDASSARLAGALAARGVVAGSRVGLCCERSPEMVLAIVAVLRCGAAYIPLDPEAPPERVSRIVADASPV
LLLTQRRLAPRLPAATVPQLLLDDAAWREAAPLPPQAIPPEAIAYVIYTSGSTGMPKGVANTHRALLNRLDWQNTLLRGG
ITARTLQKTPYTFDVSVWELLWPLLNGAALVVAPPGLHRDPTGLASLMREAGVAVAHFVPSMLNAFLDVMPGRQLPDLAL
VICSGEALLAEQAERFRRLLPGTRLVNLYGPTEAAIDVSAWPCESATPAGRAGIPIGRPIDNVSLYVLDSRLSPCPPGQR
GELYIGGAALAAGYLGRPDLTAASFVPDPLSDRPGARMYRTGDIAMFGEHGELHYLGRRDEQVKLNGNRIELREIEACLL
ALPGVAQCAVVPVAVNGRIRHLHGFVEPAAGGQRWAEGELEDWLASRLPEVMRPARIEVVERIALLTAGKIDRKRLRQQA
QAALERTASTSLARPKTAFQRDIATEWSAVLETGEIGADENFFMLGGSSVQAIQLIGRLNRRFGLLLTPAMLFNAPQLDR
FSAQVLAELGRHAQREGTLAALLDGLGPEDMDELLKLFEARELA

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=627, Percent_Identity=22.1690590111643, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI187761345, Length=538, Percent_Identity=26.3940520446097, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI187761343, Length=538, Percent_Identity=26.3940520446097, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI42544132, Length=512, Percent_Identity=22.265625, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI115511026, Length=532, Percent_Identity=22.3684210526316, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI58082049, Length=514, Percent_Identity=23.1517509727626, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI157311624, Length=513, Percent_Identity=23.0019493177388, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI157311622, Length=513, Percent_Identity=23.0019493177388, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI38505220, Length=524, Percent_Identity=25, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI156151445, Length=577, Percent_Identity=21.317157712305, Blast_Score=81, Evalue=6e-15,
Organism=Escherichia coli, GI1786801, Length=1092, Percent_Identity=31.5934065934066, Blast_Score=377, Evalue=1e-105,
Organism=Escherichia coli, GI1788107, Length=558, Percent_Identity=26.5232974910394, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1786810, Length=523, Percent_Identity=26.0038240917782, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI145693145, Length=555, Percent_Identity=23.4234234234234, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788595, Length=492, Percent_Identity=27.4390243902439, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790505, Length=558, Percent_Identity=22.7598566308244, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556356, Length=1079, Percent_Identity=22.613531047266, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17557194, Length=546, Percent_Identity=24.9084249084249, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=539, Percent_Identity=24.860853432282, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538037, Length=534, Percent_Identity=23.5955056179775, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560140, Length=424, Percent_Identity=24.5283018867925, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17559526, Length=445, Percent_Identity=24.9438202247191, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985884, Length=382, Percent_Identity=23.0366492146597, Blast_Score=77, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=765, Percent_Identity=24.0522875816993, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319699, Length=379, Percent_Identity=22.1635883905013, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24648676, Length=578, Percent_Identity=30.6228373702422, Blast_Score=227, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19922652, Length=437, Percent_Identity=26.5446224256293, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24656500, Length=516, Percent_Identity=23.062015503876, Blast_Score=94, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21356947, Length=488, Percent_Identity=21.5163934426229, Blast_Score=80, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582852, Length=432, Percent_Identity=23.6111111111111, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355181, Length=446, Percent_Identity=23.542600896861, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581924, Length=398, Percent_Identity=24.1206030150754, Blast_Score=74, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 118509; Mature: 118378

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTPLSAYQYRFWLEWRLAPHSAAYTTALVYRLIGPLRRDALQQALEAFVHEHDEGCRS
CCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VFRDDGGDPVRIVHPRIEVDLEYRDARGDGPAQPALDAAARDAWIAERAATVFALDRAPL
HHHCCCCCCEEEECCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCH
FRFSLLREDDATHRLVLAFPHIISDAFSARYINARLSALYNHALGAGPAPDRTHRDLDGF
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LALEAEYRASGARQADLDYWLALLGEAPLGVDLPAPETAEAGARDCIHRMHFDATVAQAL
EEEEEHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KACAKANRSTPFLLLSSLFAIALARWLDLPELVLSYPVNLRSPGFEQTSGCFVNNLPMPI
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCEE
ALRDDDSFRDVFARTTAQRAASRRRQRLALTDLVAALRRRRTLADEPIFNVGITEAFFTQ
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
SSPLDFRQVASELLPAAATERPLDLNFAYQLTPDGLHVNLEHDTRHLSPARIAAFAARFE
CCCCCHHHHHHHHHCHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHH
RLLAACLADDTQAVHAVALLGAEERERLSRFWHGPARALDDSHWYARFAAQCAASPDAIA
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHCCCCCCEE
VEAGETRLSYRELDASSARLAGALAARGVVAGSRVGLCCERSPEMVLAIVAVLRCGAAYI
EECCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHCCCEEE
PLDPEAPPERVSRIVADASPVLLLTQRRLAPRLPAATVPQLLLDDAAWREAAPLPPQAIP
CCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PEAIAYVIYTSGSTGMPKGVANTHRALLNRLDWQNTLLRGGITARTLQKTPYTFDVSVWE
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHHCCCCCEECHHHHH
LLWPLLNGAALVVAPPGLHRDPTGLASLMREAGVAVAHFVPSMLNAFLDVMPGRQLPDLA
HHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEE
LVICSGEALLAEQAERFRRLLPGTRLVNLYGPTEAAIDVSAWPCESATPAGRAGIPIGRP
EEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCC
IDNVSLYVLDSRLSPCPPGQRGELYIGGAALAAGYLGRPDLTAASFVPDPLSDRPGARMY
CCCEEEEEEECCCCCCCCCCCCCEEECHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCEE
RTGDIAMFGEHGELHYLGRRDEQVKLNGNRIELREIEACLLALPGVAQCAVVPVAVNGRI
EECCEEEECCCCCEEECCCCCCEEEECCCEEEHHHHHHHHHHCCCCHHHEEEEEEECCEE
RHLHGFVEPAAGGQRWAEGELEDWLASRLPEVMRPARIEVVERIALLTAGKIDRKRLRQQ
EEHHHHCCCCCCCCCCCCCHHHHHHHHHCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
AQAALERTASTSLARPKTAFQRDIATEWSAVLETGEIGADENFFMLGGSSVQAIQLIGRL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHH
NRRFGLLLTPAMLFNAPQLDRFSAQVLAELGRHAQREGTLAALLDGLGPEDMDELLKLFE
HHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHH
ARELA
HHCCC
>Mature Secondary Structure 
STTPLSAYQYRFWLEWRLAPHSAAYTTALVYRLIGPLRRDALQQALEAFVHEHDEGCRS
CCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VFRDDGGDPVRIVHPRIEVDLEYRDARGDGPAQPALDAAARDAWIAERAATVFALDRAPL
HHHCCCCCCEEEECCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCH
FRFSLLREDDATHRLVLAFPHIISDAFSARYINARLSALYNHALGAGPAPDRTHRDLDGF
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
LALEAEYRASGARQADLDYWLALLGEAPLGVDLPAPETAEAGARDCIHRMHFDATVAQAL
EEEEEHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KACAKANRSTPFLLLSSLFAIALARWLDLPELVLSYPVNLRSPGFEQTSGCFVNNLPMPI
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCEE
ALRDDDSFRDVFARTTAQRAASRRRQRLALTDLVAALRRRRTLADEPIFNVGITEAFFTQ
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
SSPLDFRQVASELLPAAATERPLDLNFAYQLTPDGLHVNLEHDTRHLSPARIAAFAARFE
CCCCCHHHHHHHHHCHHCCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHH
RLLAACLADDTQAVHAVALLGAEERERLSRFWHGPARALDDSHWYARFAAQCAASPDAIA
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHCCCCCCEE
VEAGETRLSYRELDASSARLAGALAARGVVAGSRVGLCCERSPEMVLAIVAVLRCGAAYI
EECCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHCCCEEE
PLDPEAPPERVSRIVADASPVLLLTQRRLAPRLPAATVPQLLLDDAAWREAAPLPPQAIP
CCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
PEAIAYVIYTSGSTGMPKGVANTHRALLNRLDWQNTLLRGGITARTLQKTPYTFDVSVWE
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHHHHCCCCCEECHHHHH
LLWPLLNGAALVVAPPGLHRDPTGLASLMREAGVAVAHFVPSMLNAFLDVMPGRQLPDLA
HHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCEE
LVICSGEALLAEQAERFRRLLPGTRLVNLYGPTEAAIDVSAWPCESATPAGRAGIPIGRP
EEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCC
IDNVSLYVLDSRLSPCPPGQRGELYIGGAALAAGYLGRPDLTAASFVPDPLSDRPGARMY
CCCEEEEEEECCCCCCCCCCCCCEEECHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCEE
RTGDIAMFGEHGELHYLGRRDEQVKLNGNRIELREIEACLLALPGVAQCAVVPVAVNGRI
EECCEEEECCCCCEEECCCCCCEEEECCCEEEHHHHHHHHHHCCCCHHHEEEEEEECCEE
RHLHGFVEPAAGGQRWAEGELEDWLASRLPEVMRPARIEVVERIALLTAGKIDRKRLRQQ
EEHHHHCCCCCCCCCCCCCHHHHHHHHHCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
AQAALERTASTSLARPKTAFQRDIATEWSAVLETGEIGADENFFMLGGSSVQAIQLIGRL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHH
NRRFGLLLTPAMLFNAPQLDRFSAQVLAELGRHAQREGTLAALLDGLGPEDMDELLKLFE
HHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHH
ARELA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA