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The map label for this gene is panE [C]

Identifier: 238024361

GI number: 238024361

Start: 1173965

End: 1174915

Strand: Direct

Name: panE [C]

Synonym: bglu_2g09540

Alternate gene names: 238024361

Gene position: 1173965-1174915 (Clockwise)

Preceding gene: 238024359

Following gene: 238024362

Centisome position: 41.52

GC content: 69.61

Gene sequence:

>951_bases
TTGAAAATTGCGATGCTGGGAGCCGGTGCGCTGGGCTGCGCGATCGGCGCGACGCTCACCGAAGGCGGTCACGAGACCTG
GCTGATCGACCGCTCGCCGGCCCATGTCGAGGCGATGCGCACCCATGGCCTGCGCGTCGACGACGCGCGCGGCTCGCGCC
AGGTGCGGGTTCTCGCGACCACCGATGCCAGCGAGGCGGGCATGGCCGACGTGGTGATCGTGCTCGTCAAATCGTTCCAG
ACCGACGCGGCGATTCGCGGTGCCCAGGCGCTGGTTGGACCCGACACGCTGGTCCTGTCGCTGCAGAACGGGCTCGGCCA
TGAAGACATCCTCGCCGATGCCGTGGGCCGCGAACGGGTGCTCGCGGGCAAGACCTACGTGGGCGGCGTGCTGCGCGGCG
CCGGCCATATCGAGTCGGGGGTGGTCGGCAAGCACACCATCATCGGCGAACTGGACGGGCGCGTGAGCCCGCGCGTGCAA
CGCCTCGCCGCGGCATTCAGCAGCGCGGGACTCGCCACCCAGGTCAGCGACAACATCGTCGGCGCGATGTGGGACAAGCT
GCTGGTGAACGTCGCGACGGGCGCGCTGACCGGCATCACGTCGCTCACCTATGGCCAGCTCTACGACGAGCCGCTGCTCA
AGGCCGCGTCGCTCGCGGCCGTCGCCGAAGCGATCGCGGCCGCGCAAGCCGCCGGCGTCACGCTGTCGATGACCGATCCC
GAGCAGGCCTGGACGCTGGCCGCGCAAGGCCTGCCCGCGACGTTCAAGACCTCGATGCTGCAGAGCCTGGAAAAGGGCTC
GGTGACCGAAATCGACTTCATCAACGGTTCGGTCGTGCGCTGGGGCGAGCGCCACGGCGTGCCGACGCCCGTCAACGCCA
CGCTCGTGGCCTGCATCAAGGGAATCGAGCGCGCGATGGCGGATCGCCGGAAAGCGGGAGCCCAGGCATGA

Upstream 100 bases:

>100_bases
CATCAGCAATATTGAATAATGCAATGATGCCATTTTCTCCATTGCATTGCGACATCGTGCAGCGCCGCTTATCGTGACCT
CACACGTTAAGGAGACGCTC

Downstream 100 bases:

>100_bases
GCGCGCCGCGAGCCTATCTCGAACACGTCGCCGTTTTCGTGCGCGACATCCACTGGCACATCCGCTTTTTCGAGGACGTG
TTCGGCATGACGATGCGCGA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKIAMLGAGALGCAIGATLTEGGHETWLIDRSPAHVEAMRTHGLRVDDARGSRQVRVLATTDASEAGMADVVIVLVKSFQ
TDAAIRGAQALVGPDTLVLSLQNGLGHEDILADAVGRERVLAGKTYVGGVLRGAGHIESGVVGKHTIIGELDGRVSPRVQ
RLAAAFSSAGLATQVSDNIVGAMWDKLLVNVATGALTGITSLTYGQLYDEPLLKAASLAAVAEAIAAAQAAGVTLSMTDP
EQAWTLAAQGLPATFKTSMLQSLEKGSVTEIDFINGSVVRWGERHGVPTPVNATLVACIKGIERAMADRRKAGAQA

Sequences:

>Translated_316_residues
MKIAMLGAGALGCAIGATLTEGGHETWLIDRSPAHVEAMRTHGLRVDDARGSRQVRVLATTDASEAGMADVVIVLVKSFQ
TDAAIRGAQALVGPDTLVLSLQNGLGHEDILADAVGRERVLAGKTYVGGVLRGAGHIESGVVGKHTIIGELDGRVSPRVQ
RLAAAFSSAGLATQVSDNIVGAMWDKLLVNVATGALTGITSLTYGQLYDEPLLKAASLAAVAEAIAAAQAAGVTLSMTDP
EQAWTLAAQGLPATFKTSMLQSLEKGSVTEIDFINGSVVRWGERHGVPTPVNATLVACIKGIERAMADRRKAGAQA
>Mature_316_residues
MKIAMLGAGALGCAIGATLTEGGHETWLIDRSPAHVEAMRTHGLRVDDARGSRQVRVLATTDASEAGMADVVIVLVKSFQ
TDAAIRGAQALVGPDTLVLSLQNGLGHEDILADAVGRERVLAGKTYVGGVLRGAGHIESGVVGKHTIIGELDGRVSPRVQ
RLAAAFSSAGLATQVSDNIVGAMWDKLLVNVATGALTGITSLTYGQLYDEPLLKAASLAAVAEAIAAAQAAGVTLSMTDP
EQAWTLAAQGLPATFKTSMLQSLEKGSVTEIDFINGSVVRWGERHGVPTPVNATLVACIKGIERAMADRRKAGAQA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=312, Percent_Identity=27.8846153846154, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32633; Mature: 32633

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAMLGAGALGCAIGATLTEGGHETWLIDRSPAHVEAMRTHGLRVDDARGSRQVRVLAT
CEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCEEECCCCCCEEEEEEE
TDASEAGMADVVIVLVKSFQTDAAIRGAQALVGPDTLVLSLQNGLGHEDILADAVGRERV
CCCCCCCHHHHHHHHHHHHCCHHHHCCCHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHE
LAGKTYVGGVLRGAGHIESGVVGKHTIIGELDGRVSPRVQRLAAAFSSAGLATQVSDNIV
EECCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEHHHHHHH
GAMWDKLLVNVATGALTGITSLTYGQLYDEPLLKAASLAAVAEAIAAAQAAGVTLSMTDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
EQAWTLAAQGLPATFKTSMLQSLEKGSVTEIDFINGSVVRWGERHGVPTPVNATLVACIK
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHCCCCCCCHHHHHHHHH
GIERAMADRRKAGAQA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIAMLGAGALGCAIGATLTEGGHETWLIDRSPAHVEAMRTHGLRVDDARGSRQVRVLAT
CEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCEEECCCCCCEEEEEEE
TDASEAGMADVVIVLVKSFQTDAAIRGAQALVGPDTLVLSLQNGLGHEDILADAVGRERV
CCCCCCCHHHHHHHHHHHHCCHHHHCCCHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHE
LAGKTYVGGVLRGAGHIESGVVGKHTIIGELDGRVSPRVQRLAAAFSSAGLATQVSDNIV
EECCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEHHHHHHH
GAMWDKLLVNVATGALTGITSLTYGQLYDEPLLKAASLAAVAEAIAAAQAAGVTLSMTDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
EQAWTLAAQGLPATFKTSMLQSLEKGSVTEIDFINGSVVRWGERHGVPTPVNATLVACIK
HHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHCCCCCCCHHHHHHHHH
GIERAMADRRKAGAQA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]