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The map label for this gene is frlR [H]

Identifier: 238024240

GI number: 238024240

Start: 1001389

End: 1002219

Strand: Direct

Name: frlR [H]

Synonym: bglu_2g08220

Alternate gene names: 238024240

Gene position: 1001389-1002219 (Clockwise)

Preceding gene: 238024234

Following gene: 238024241

Centisome position: 35.42

GC content: 68.35

Gene sequence:

>831_bases
ATGCGCGCCATGACATCCAACCAGGCGAACGCGGCGAATCCCAACGCCCCCGGCCAAGGCCCGGCCGGCGGCGAAGTAGC
GCCTGCGGCAGCGCCGTTGCCGTCGCCATCGCCGTCTCCCACCTTCAGCCCTTTATATCAGCAGATCAAGGCATTGATCA
CGCAGGGCCTGGAGTCGGGTGAATGGAAGCCGGGTGAAATCATCCCGAGCGAGGTCGAGCTCGCGGCGCGCTACAAGGTG
AGCCAGGGCACGGTGCGCAAGGCGATCGACGAGTTGGCGGCCGACAACCTGCTGGTGCGCCGGCAGGGCAAGGGCACCTT
CGTGGCCACCCACAGCGAGGAGCGTGCCCAGTTCCGCTTCCTGCGCCTGCTGGCCGAGGACGGCGTGGAGCACCCGCACG
TGAGCCGGCTGCTGGAATGCCGCCGCACCCGGGCGCCGGCCGAGATCGCGCGGCAGCTGGACCTGAAGCCGGCCGACCCG
GTGGTCCAGGTGCGCCGGCTGCTGGAGTTCGACGGCGTCGCCACGGTGCTCGACGAGATCTGGCTGCCGGGCGCGATGTT
CCGCGGGCTCACGTTCGAGCGCCTCAGCGAGTACAAGGGCCCGCTCTACGCGATGTTCGAGTCGGAGTTCGGCACGCGCA
TGATCCGCGCCACCGAGAAGGTCCGCGCGATCGCCGCGGAGCCCGCCGTGGCGGTGCTGCTGGGCGTGGCCGACGGATTT
CCGTTGCTGTCGGTCGAGCGCGTGTCCTATACCTATGGGGACCGCCCCGTCGAGGTGCGGCGCGGTTGGTATGTCACAAC
CGGGTATTACTATCAGAACGAATTGAGTTGA

Upstream 100 bases:

>100_bases
TAGGAGTGCGATCGGGCAAAGTCAAACGGTATCATATGTCTTATATAAGACAGATGTATTGCGGGAAAAATCTGGACGTA
AAAGTCAGCTTTGTGTTGAA

Downstream 100 bases:

>100_bases
CGGGCCGCCGCGGTATCGATCCGGCGGTGCGTCGAGGAAATGGGGAACGAGCTCGCGCCCACACGCGAGGCACGTTCAGG
GCCGTCATTGTTCGCTGCAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MRAMTSNQANAANPNAPGQGPAGGEVAPAAAPLPSPSPSPTFSPLYQQIKALITQGLESGEWKPGEIIPSEVELAARYKV
SQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLAEDGVEHPHVSRLLECRRTRAPAEIARQLDLKPADP
VVQVRRLLEFDGVATVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRATEKVRAIAAEPAVAVLLGVADGF
PLLSVERVSYTYGDRPVEVRRGWYVTTGYYYQNELS

Sequences:

>Translated_276_residues
MRAMTSNQANAANPNAPGQGPAGGEVAPAAAPLPSPSPSPTFSPLYQQIKALITQGLESGEWKPGEIIPSEVELAARYKV
SQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLAEDGVEHPHVSRLLECRRTRAPAEIARQLDLKPADP
VVQVRRLLEFDGVATVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRATEKVRAIAAEPAVAVLLGVADGF
PLLSVERVSYTYGDRPVEVRRGWYVTTGYYYQNELS
>Mature_276_residues
MRAMTSNQANAANPNAPGQGPAGGEVAPAAAPLPSPSPSPTFSPLYQQIKALITQGLESGEWKPGEIIPSEVELAARYKV
SQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRFLRLLAEDGVEHPHVSRLLECRRTRAPAEIARQLDLKPADP
VVQVRRLLEFDGVATVLDEIWLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRATEKVRAIAAEPAVAVLLGVADGF
PLLSVERVSYTYGDRPVEVRRGWYVTTGYYYQNELS

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=222, Percent_Identity=29.2792792792793, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=28.936170212766, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790540, Length=222, Percent_Identity=29.2792792792793, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790118, Length=210, Percent_Identity=28.0952380952381, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 30413; Mature: 30413

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMTSNQANAANPNAPGQGPAGGEVAPAAAPLPSPSPSPTFSPLYQQIKALITQGLESG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
EWKPGEIIPSEVELAARYKVSQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRF
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHH
LRLLAEDGVEHPHVSRLLECRRTRAPAEIARQLDLKPADPVVQVRRLLEFDGVATVLDEI
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHH
WLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRATEKVRAIAAEPAVAVLLGVADGF
HCCHHHHHCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHCCCC
PLLSVERVSYTYGDRPVEVRRGWYVTTGYYYQNELS
CCEEEEHEEHCCCCCCEEEECCEEEEECEEECCCCC
>Mature Secondary Structure
MRAMTSNQANAANPNAPGQGPAGGEVAPAAAPLPSPSPSPTFSPLYQQIKALITQGLESG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
EWKPGEIIPSEVELAARYKVSQGTVRKAIDELAADNLLVRRQGKGTFVATHSEERAQFRF
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCEEEECCHHHHHHHH
LRLLAEDGVEHPHVSRLLECRRTRAPAEIARQLDLKPADPVVQVRRLLEFDGVATVLDEI
HHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHH
WLPGAMFRGLTFERLSEYKGPLYAMFESEFGTRMIRATEKVRAIAAEPAVAVLLGVADGF
HCCHHHHHCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHCCCC
PLLSVERVSYTYGDRPVEVRRGWYVTTGYYYQNELS
CCEEEEHEEHCCCCCCEEEECCEEEEECEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]