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The map label for this gene is fabF [H]

Identifier: 238024213

GI number: 238024213

Start: 954602

End: 955876

Strand: Direct

Name: fabF [H]

Synonym: bglu_2g07930

Alternate gene names: 238024213

Gene position: 954602-955876 (Clockwise)

Preceding gene: 238024212

Following gene: 238024214

Centisome position: 33.76

GC content: 68.16

Gene sequence:

>1275_bases
ATGAAGCTGCGATCGGACGCAATCGTCATCAGCGCATTCGGCGCTGTCACACCACTCGGCGGCAGCTACGACGAACTGCA
TGCCGCGCTCCGCGAAGGCCGCTCCGGCATTCGCCGGATCGAGAAGTTCGATTGCTCGACCTACACGACCGAACACGCGG
GCGTGCCCGACGAGGGCAACGAGCGCGTGCGCTGGCCTTCCGCGCGGCGGGTCGGCACCGAGCAGCTGTATGGCGAGCTC
GCGGCGGCGCGGCTGCTCGCGCAGGCGCCGTTCGTTGCGCGCGACTACGCGCCGGAGCGCATCGGCTGCCTGGTCGGCGT
CGACGCGCCGGCCACCGACGTGCAGAGCGCGCTCGAGCTCGTCGACAAGCTCAAGGATGAAAAATCACGCGACGCGCTGA
TTCGCGTGCTGGTTTCGCACATGCGGATGAGCGAGTTCGTGAGTGGCGATGCGACCGCCGTGTTCGGCGCGATTCATCGC
CATATTCCGTTCAGCGGTTGCGCGCTCGCACACGTGGGCTTGTGCTCCGCGTCGCTGCAGGCGATCGGCATGGGCATGCT
CGCGCTGCGTCAGGGGCGCATCGACGCGGCCATCGTCGGCGGCGTGTCGGGCAAGGTCAATCCGCTCAATCTCGCGCGGC
TCGAATCGCTCGACGTGATCTCGACCGACCTGAAGCTCGACCCTCGGCACCGTTCGCGGCCGTTCGACACGCGCCGCTCC
GGCTTCGTGCTCGCGGAAGGCGCGGTGCTGTTCCTGATCGAGCGCGAGTCGGCCGTCCGTGCCCGGGGCGATACGCCGCT
TGGGCGGGTGGCCGGCTACGGAGCGAGCCTGGCCGCCGAGCACATCGTGATTCCCCACCTGCAGTCGCTCGAGATGCGGC
TCGCGATGCAGCGCGCCCTCGCCGATGCGGGATGCGCGCCCGGCGATATCGACTACATCAACGCGCACGGGACGTCGACG
GTGCTCAACGACAAGCACGAATCGGAGGCGATCCGCGCGATCTTCCCCATGCAGCCCCGGATTCCCGTTACCGCCAACAA
ATCGCAGCACGGGCACCTGATCGCGACGGCCGGCGCGATGGAGGTGCTGAACACCGTAATCGGACTGCGGGAACGCTTCA
TCCCGGCGACTATCAACCTCGACGAGCAGGCGCAGGAGTGCCCCGTGAACGTCGTCCGCGCGCCGATGCCCAGCCATGCG
CGGCGCGTGCTCAAGAACTCGTTCGGCATGGGCGGTCTCGCGGCTTCGCTCGTGCTGGAAGGAGCGGCCGCATGA

Upstream 100 bases:

>100_bases
ATCCGGCCATTCCGATCGGCGCGGCCGTGCTGGTCAACGGCATCGGCGTGTCGTCGGGCCTCGGTGCGATCCTGGTTCGC
AAGCTGAGCGGGGTGGGGCG

Downstream 100 bases:

>100_bases
AGTTCACTTCGCTGCTGGCCCGGGAGGCGAACTGGCATCTCGTCGTGAACGGGACGCGCCTGAGGGCGGAAGACCTGCGC
GCACGGCTGAGGGCCGCGCG

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKLRSDAIVISAFGAVTPLGGSYDELHAALREGRSGIRRIEKFDCSTYTTEHAGVPDEGNERVRWPSARRVGTEQLYGEL
AAARLLAQAPFVARDYAPERIGCLVGVDAPATDVQSALELVDKLKDEKSRDALIRVLVSHMRMSEFVSGDATAVFGAIHR
HIPFSGCALAHVGLCSASLQAIGMGMLALRQGRIDAAIVGGVSGKVNPLNLARLESLDVISTDLKLDPRHRSRPFDTRRS
GFVLAEGAVLFLIERESAVRARGDTPLGRVAGYGASLAAEHIVIPHLQSLEMRLAMQRALADAGCAPGDIDYINAHGTST
VLNDKHESEAIRAIFPMQPRIPVTANKSQHGHLIATAGAMEVLNTVIGLRERFIPATINLDEQAQECPVNVVRAPMPSHA
RRVLKNSFGMGGLAASLVLEGAAA

Sequences:

>Translated_424_residues
MKLRSDAIVISAFGAVTPLGGSYDELHAALREGRSGIRRIEKFDCSTYTTEHAGVPDEGNERVRWPSARRVGTEQLYGEL
AAARLLAQAPFVARDYAPERIGCLVGVDAPATDVQSALELVDKLKDEKSRDALIRVLVSHMRMSEFVSGDATAVFGAIHR
HIPFSGCALAHVGLCSASLQAIGMGMLALRQGRIDAAIVGGVSGKVNPLNLARLESLDVISTDLKLDPRHRSRPFDTRRS
GFVLAEGAVLFLIERESAVRARGDTPLGRVAGYGASLAAEHIVIPHLQSLEMRLAMQRALADAGCAPGDIDYINAHGTST
VLNDKHESEAIRAIFPMQPRIPVTANKSQHGHLIATAGAMEVLNTVIGLRERFIPATINLDEQAQECPVNVVRAPMPSHA
RRVLKNSFGMGGLAASLVLEGAAA
>Mature_424_residues
MKLRSDAIVISAFGAVTPLGGSYDELHAALREGRSGIRRIEKFDCSTYTTEHAGVPDEGNERVRWPSARRVGTEQLYGEL
AAARLLAQAPFVARDYAPERIGCLVGVDAPATDVQSALELVDKLKDEKSRDALIRVLVSHMRMSEFVSGDATAVFGAIHR
HIPFSGCALAHVGLCSASLQAIGMGMLALRQGRIDAAIVGGVSGKVNPLNLARLESLDVISTDLKLDPRHRSRPFDTRRS
GFVLAEGAVLFLIERESAVRARGDTPLGRVAGYGASLAAEHIVIPHLQSLEMRLAMQRALADAGCAPGDIDYINAHGTST
VLNDKHESEAIRAIFPMQPRIPVTANKSQHGHLIATAGAMEVLNTVIGLRERFIPATINLDEQAQECPVNVVRAPMPSHA
RRVLKNSFGMGGLAASLVLEGAAA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=255, Percent_Identity=36.4705882352941, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=36.6666666666667, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI41872631, Length=265, Percent_Identity=28.6792452830189, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1787337, Length=422, Percent_Identity=29.6208530805687, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1788663, Length=417, Percent_Identity=26.378896882494, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71983541, Length=427, Percent_Identity=30.4449648711944, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI71983535, Length=252, Percent_Identity=35.7142857142857, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI212642053, Length=267, Percent_Identity=26.5917602996255, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=451, Percent_Identity=26.6075388026608, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24644341, Length=428, Percent_Identity=31.3084112149533, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI19920632, Length=283, Percent_Identity=26.1484098939929, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221330659, Length=283, Percent_Identity=26.1484098939929, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24581345, Length=289, Percent_Identity=24.5674740484429, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 45388; Mature: 45388

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRSDAIVISAFGAVTPLGGSYDELHAALREGRSGIRRIEKFDCSTYTTEHAGVPDEGN
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ERVRWPSARRVGTEQLYGELAAARLLAQAPFVARDYAPERIGCLVGVDAPATDVQSALEL
CCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCCHHHHHHHHHH
VDKLKDEKSRDALIRVLVSHMRMSEFVSGDATAVFGAIHRHIPFSGCALAHVGLCSASLQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AIGMGMLALRQGRIDAAIVGGVSGKVNPLNLARLESLDVISTDLKLDPRHRSRPFDTRRS
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCEEECCCEECCCCCCCCCCCCCC
GFVLAEGAVLFLIERESAVRARGDTPLGRVAGYGASLAAEHIVIPHLQSLEMRLAMQRAL
CEEEECCEEEEEEECCCHHHCCCCCCHHHHHCCCHHHHHCCEECCCHHHHHHHHHHHHHH
ADAGCAPGDIDYINAHGTSTVLNDKHESEAIRAIFPMQPRIPVTANKSQHGHLIATAGAM
HHCCCCCCCCCEEECCCCCHHCCCCHHHHHHHHHCCCCCCCCEECCCCCCCCEEEEHHHH
EVLNTVIGLRERFIPATINLDEQAQECPVNVVRAPMPSHARRVLKNSFGMGGLAASLVLE
HHHHHHHHHHHHCCCEEECCCHHHHHCCCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
GAAA
CCCC
>Mature Secondary Structure
MKLRSDAIVISAFGAVTPLGGSYDELHAALREGRSGIRRIEKFDCSTYTTEHAGVPDEGN
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ERVRWPSARRVGTEQLYGELAAARLLAQAPFVARDYAPERIGCLVGVDAPATDVQSALEL
CCCCCCCHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEECCCCHHHHHHHHHH
VDKLKDEKSRDALIRVLVSHMRMSEFVSGDATAVFGAIHRHIPFSGCALAHVGLCSASLQ
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AIGMGMLALRQGRIDAAIVGGVSGKVNPLNLARLESLDVISTDLKLDPRHRSRPFDTRRS
HHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCEEECCCEECCCCCCCCCCCCCC
GFVLAEGAVLFLIERESAVRARGDTPLGRVAGYGASLAAEHIVIPHLQSLEMRLAMQRAL
CEEEECCEEEEEEECCCHHHCCCCCCHHHHHCCCHHHHHCCEECCCHHHHHHHHHHHHHH
ADAGCAPGDIDYINAHGTSTVLNDKHESEAIRAIFPMQPRIPVTANKSQHGHLIATAGAM
HHCCCCCCCCCEEECCCCCHHCCCCHHHHHHHHHCCCCCCCCEECCCCCCCCEEEEHHHH
EVLNTVIGLRERFIPATINLDEQAQECPVNVVRAPMPSHARRVLKNSFGMGGLAASLVLE
HHHHHHHHHHHHCCCEEECCCHHHHHCCCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
GAAA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]