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The map label for this gene is pcp [H]

Identifier: 238023875

GI number: 238023875

Start: 495832

End: 497412

Strand: Direct

Name: pcp [H]

Synonym: bglu_2g04140

Alternate gene names: 238023875

Gene position: 495832-497412 (Clockwise)

Preceding gene: 238023874

Following gene: 238023876

Centisome position: 17.54

GC content: 71.54

Gene sequence:

>1581_bases
ATGGCAAGGCATCTTCACGCAGGCAGCGAGCCGAAGGTCATCACCGAATCCCAATGCGTCGGCGCCTGCGATCCTGCCGA
ACGGATACATGTGACGGTGATGCTGCGGCGCGAGGGAGAACAGGCGCTCGACGCCCTGGTCGACCGGCTCGCGAGCGGCG
ACCCGGCCGCCAAGCCGGTGTCGCGCGAGGATTTCGCCCAGCACTTCGGCTCGCGCGAGGACGACGTCAAGCGCACCGAG
GCGTTCGCGCGCCAGCATCACCTGACGGTCGAGCGCGTCGACCCGCTGGAAAGCGTGGTCGTGCTGGCCGGCACCATCGA
GCAGTTCGAGCGCGCGTTCGGCGTCAAGCTGCAGCAATACCAGCACCACGCGGTCGGCAAGTTTCGCGCATGCACCGGCG
CGATCGCACTGCCCGACGAGCTACACGACGCCGTCACCGCCGTGCTCGGCCTCGACACGCGGCCGCAGGCGCACCCGCAT
TTCCGCTTCCGCCCGCCGTTCCAGCCTGCCCGCGGCACCGCCGGGACCACCTACACGCCGGTGCAGCTCGCCTCGATCTA
TGACTTCCCGGCCGGCGACGGCGCCGGCCAGTGCATCGCGCTGATCGAACTGGGCGGCGGCTATCGCACGGCCGACATCA
ACGGCTACTTCGACCAGCTCGGCCTGCCGCGTCCGACGCTCGTCGACATCAGCGTGGCGGGCGGCAGCAATGCGCCGACC
GGCGACCCGAACGGCCCGGACGGCGAGGTCGCGCTCGACATCGAGGTGGCCGGGGCGATCGCGCCCGGCGCCACCATCGC
CGTCTATTTCGCGCCGAACAGCGATTCGGGCTTCATCCAGGCCGTGAACCAGGCGATCCACGACACCAAGAACCATCCGT
CGGTGGTGTCGATCAGTTGGGGCGGCCCCGAGGCCGGCTGGACCCGGCAGTCGATCCAGGCCTTCAACAACGTGCTGAAG
TCGGCCGCCGCGCTCGGCGTGACGATCTGCGCGGCCTCCGGCGACAACGGTTCCGGCGACGGCCTGCAGGACGGCTCGAA
CCACGTCGATTTTCCGGCGTCGAGCCCCTACGTGCTCGCCTGCGGCGGCACCACGCTCGACGCCCAGGCGGGCCAGGGCA
TCCGCAGCGAGGTGGTGTGGAACGACGAGGCAGCCGGCGGCGGCGCGGGCGGCGGCGTGAGCGCCGTGTTCGACGCGCCG
CCCTATCAGAAGGGGCTCTCGGCGGCGCTGAAGGGCGGCGGCAGCACGCCGCTCACCAAGCGCGGCGTGCCCGACGTGGC
CGGCGACGCCTCGCCGACCACCGGCTATCAGATATCGGTGGCCGGCACCACCGCCGTGATGGGCGGTACCAGCGCCGTGG
CGCCGCTGTGGGCCGCGCTGATCGCGCGCATCAACGCCGCGGCGGGCAGCCCGGTCGGCTGGGCCAATCCGAAGCTGTAC
GCGCAGCCCTCGGCATTCCACGACATAACGCGCGGCAACAACGGCGCCTTTGCGGCCGCCGCCGGCTGGGACGCCTGCAC
GGGCCTCGGCAGCCCCGACGGCAAGCAGATCGCGGCCGTGCTGCAAGGCGCGGCGCACTAG

Upstream 100 bases:

>100_bases
TCGTTGAGAGCGCGACGCCGGCGGCCCGCCAGCCACGCATCCGGCAGGCCGGATCGGATTTTCCGTAGTCCGTACACGCG
GTAACTTGGAGGGTCATAAC

Downstream 100 bases:

>100_bases
GCGCGCGGCGCGGGCGCCGCCGGCCGGCGCGGGCGCCGCCGCGCGACCCGCGCACGGGCACGGGCACGGGCGAGCGGTGC
CGGGCGGAACCGGCGGCTGG

Product: Serine protease, kumamolysin

Products: NA

Alternate protein names: Pepstatin-insensitive carboxyl proteinase; Pseudomonapepsin [H]

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MARHLHAGSEPKVITESQCVGACDPAERIHVTVMLRREGEQALDALVDRLASGDPAAKPVSREDFAQHFGSREDDVKRTE
AFARQHHLTVERVDPLESVVVLAGTIEQFERAFGVKLQQYQHHAVGKFRACTGAIALPDELHDAVTAVLGLDTRPQAHPH
FRFRPPFQPARGTAGTTYTPVQLASIYDFPAGDGAGQCIALIELGGGYRTADINGYFDQLGLPRPTLVDISVAGGSNAPT
GDPNGPDGEVALDIEVAGAIAPGATIAVYFAPNSDSGFIQAVNQAIHDTKNHPSVVSISWGGPEAGWTRQSIQAFNNVLK
SAAALGVTICAASGDNGSGDGLQDGSNHVDFPASSPYVLACGGTTLDAQAGQGIRSEVVWNDEAAGGGAGGGVSAVFDAP
PYQKGLSAALKGGGSTPLTKRGVPDVAGDASPTTGYQISVAGTTAVMGGTSAVAPLWAALIARINAAAGSPVGWANPKLY
AQPSAFHDITRGNNGAFAAAAGWDACTGLGSPDGKQIAAVLQGAAH

Sequences:

>Translated_526_residues
MARHLHAGSEPKVITESQCVGACDPAERIHVTVMLRREGEQALDALVDRLASGDPAAKPVSREDFAQHFGSREDDVKRTE
AFARQHHLTVERVDPLESVVVLAGTIEQFERAFGVKLQQYQHHAVGKFRACTGAIALPDELHDAVTAVLGLDTRPQAHPH
FRFRPPFQPARGTAGTTYTPVQLASIYDFPAGDGAGQCIALIELGGGYRTADINGYFDQLGLPRPTLVDISVAGGSNAPT
GDPNGPDGEVALDIEVAGAIAPGATIAVYFAPNSDSGFIQAVNQAIHDTKNHPSVVSISWGGPEAGWTRQSIQAFNNVLK
SAAALGVTICAASGDNGSGDGLQDGSNHVDFPASSPYVLACGGTTLDAQAGQGIRSEVVWNDEAAGGGAGGGVSAVFDAP
PYQKGLSAALKGGGSTPLTKRGVPDVAGDASPTTGYQISVAGTTAVMGGTSAVAPLWAALIARINAAAGSPVGWANPKLY
AQPSAFHDITRGNNGAFAAAAGWDACTGLGSPDGKQIAAVLQGAAH
>Mature_525_residues
ARHLHAGSEPKVITESQCVGACDPAERIHVTVMLRREGEQALDALVDRLASGDPAAKPVSREDFAQHFGSREDDVKRTEA
FARQHHLTVERVDPLESVVVLAGTIEQFERAFGVKLQQYQHHAVGKFRACTGAIALPDELHDAVTAVLGLDTRPQAHPHF
RFRPPFQPARGTAGTTYTPVQLASIYDFPAGDGAGQCIALIELGGGYRTADINGYFDQLGLPRPTLVDISVAGGSNAPTG
DPNGPDGEVALDIEVAGAIAPGATIAVYFAPNSDSGFIQAVNQAIHDTKNHPSVVSISWGGPEAGWTRQSIQAFNNVLKS
AAALGVTICAASGDNGSGDGLQDGSNHVDFPASSPYVLACGGTTLDAQAGQGIRSEVVWNDEAAGGGAGGGVSAVFDAPP
YQKGLSAALKGGGSTPLTKRGVPDVAGDASPTTGYQISVAGTTAVMGGTSAVAPLWAALIARINAAAGSPVGWANPKLYA
QPSAFHDITRGNNGAFAAAAGWDACTGLGSPDGKQIAAVLQGAAH

Specific function: Unknown

COG id: COG4934

COG function: function code O; Predicted protease

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S53 family [H]

Homologues:

Organism=Homo sapiens, GI5729770, Length=302, Percent_Identity=28.8079470198675, Blast_Score=97, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015366
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF09286 Pro-kuma_activ [H]

EC number: =3.4.21.100 [H]

Molecular weight: Translated: 53953; Mature: 53822

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00398 RECOMBINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHLHAGSEPKVITESQCVGACDPAERIHVTVMLRREGEQALDALVDRLASGDPAAKPV
CCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
SREDFAQHFGSREDDVKRTEAFARQHHLTVERVDPLESVVVLAGTIEQFERAFGVKLQQY
CHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
QHHAVGKFRACTGAIALPDELHDAVTAVLGLDTRPQAHPHFRFRPPFQPARGTAGTTYTP
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCEECC
VQLASIYDFPAGDGAGQCIALIELGGGYRTADINGYFDQLGLPRPTLVDISVAGGSNAPT
EEEEEEECCCCCCCCCCEEEEEEECCCEEEEECCCHHHHCCCCCCCEEEEEECCCCCCCC
GDPNGPDGEVALDIEVAGAIAPGATIAVYFAPNSDSGFIQAVNQAIHDTKNHPSVVSISW
CCCCCCCCCEEEEEEEECEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEC
GGPEAGWTRQSIQAFNNVLKSAAALGVTICAASGDNGSGDGLQDGSNHVDFPASSPYVLA
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
CGGTTLDAQAGQGIRSEVVWNDEAAGGGAGGGVSAVFDAPPYQKGLSAALKGGGSTPLTK
ECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCC
RGVPDVAGDASPTTGYQISVAGTTAVMGGTSAVAPLWAALIARINAAAGSPVGWANPKLY
CCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
AQPSAFHDITRGNNGAFAAAAGWDACTGLGSPDGKQIAAVLQGAAH
ECCCHHHHHHCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ARHLHAGSEPKVITESQCVGACDPAERIHVTVMLRREGEQALDALVDRLASGDPAAKPV
CCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCC
SREDFAQHFGSREDDVKRTEAFARQHHLTVERVDPLESVVVLAGTIEQFERAFGVKLQQY
CHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
QHHAVGKFRACTGAIALPDELHDAVTAVLGLDTRPQAHPHFRFRPPFQPARGTAGTTYTP
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCEECC
VQLASIYDFPAGDGAGQCIALIELGGGYRTADINGYFDQLGLPRPTLVDISVAGGSNAPT
EEEEEEECCCCCCCCCCEEEEEEECCCEEEEECCCHHHHCCCCCCCEEEEEECCCCCCCC
GDPNGPDGEVALDIEVAGAIAPGATIAVYFAPNSDSGFIQAVNQAIHDTKNHPSVVSISW
CCCCCCCCCEEEEEEEECEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEC
GGPEAGWTRQSIQAFNNVLKSAAALGVTICAASGDNGSGDGLQDGSNHVDFPASSPYVLA
CCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
CGGTTLDAQAGQGIRSEVVWNDEAAGGGAGGGVSAVFDAPPYQKGLSAALKGGGSTPLTK
ECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCC
RGVPDVAGDASPTTGYQISVAGTTAVMGGTSAVAPLWAALIARINAAAGSPVGWANPKLY
CCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
AQPSAFHDITRGNNGAFAAAAGWDACTGLGSPDGKQIAAVLQGAAH
ECCCHHHHHHCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929375; 8576087; 10488127; 11747435; 11323721 [H]