Click here to switch to the map view.

The map label for this gene is czcD [H]

Identifier: 238023811

GI number: 238023811

Start: 410864

End: 411910

Strand: Direct

Name: czcD [H]

Synonym: bglu_2g03490

Alternate gene names: 238023811

Gene position: 410864-411910 (Clockwise)

Preceding gene: 238023810

Following gene: 238023812

Centisome position: 14.53

GC content: 69.63

Gene sequence:

>1047_bases
ATGAACGAAACATTGGGCATGAAGTCCGGACCTGTACGGCACGAGCATGTGTTTCTCGGCGCCGAGCATGCGAGCCGCGA
GCGGCGCACCTGGTTCGTGATCGCGCTCTGCGCGTTGACCATGCTGGCCGAGATCGCGGGCGGCTGGCGCTTCGGTTCGC
TGGCGCTCGTCGCCGACGGCCTGCACATGTCGACGCATGCCGGCGCGATGCTGATCGCCGCGCTCGCTTATACCTACGCG
CGGCGCCATGCGCACGATTCGCGCTTCTCGTTCGGTACCGGCAAGCTTGGCGATCTGGCCGGTTTCACGAGCGCCGTCGC
GCTCGCGCTGATCGCGGTGCTGATCGGCTATGAAGCCGTCACGCGGCTGGTCGAGCCGGTGCCGATCCGGTTCGGCGAGG
CGATTCCGATCGCCGTGTTCGGGCTCGCCGTCAATCTCAGCTGCGCCTGGCTGCTCGGCGGCGCCCACCATGGCCATGCG
CATGGCGGCCACGATCATCACGATGGTCACGATCACGCGCCGGAGCGGCATCAGGCCGATGCGGCGCATCGGCACGATCA
TGCGGACGCCGCCGCGCATCACGGCGCCCACGGCCAGCAGGCGTTTCACGCGCGCGATCACAATTTCCGCGCTGCGTATC
TGCACGTGATCGGCGATGCCGTGGTGTCGGTGCTCGCGATCGCAGGGCTGATCGCCGCGCGCGCGTTCGGCTGGAACTGG
ATGGACCCGCTGGCCGGCATCGTCGGCGCGCTGGTGATCGCCAACTGGTCGTTCGTGCTGATCCGCGACACCGGCGCGAC
GCTGCTCGACATGACGCCCGACCCCGCGCTCGCGGCGCGAATCCGCGAGCGGATCGAGGGCGACGGCGATGCGGTCGTCG
ATCTGCACCTCTGGCGTCTCGGCCCCGGCCATCTGAGCGCCGCGCTGTCGGTCGCCACCGGCAGCGCGAGCCGCGATGCG
CGCTTCTATCACCAGCGGCTGGCCGGCGTCGACGGCCTGTCGCACCTGACCGTCGAGGTCATGCCGGCGGCCGCGCCGCG
CAGCTAA

Upstream 100 bases:

>100_bases
GACGCGCCGGCGTTCCAACCTGACGAGGCCGGCGGCAGGGCGACCGAGCAACTGATCGAGGTCGTCCACAGTTACTTCAA
GTAAGGAGAGGGGAAGTGCG

Downstream 100 bases:

>100_bases
GAGAGCATGGCGCCGCGTCCCGCCCCGTGGCTCCGGCCGCCGCCGCGCCCGCTTCGGGCCGCGCCGCGGTCGGCTCGCCG
GCCTTCGTCATGAGCGGGCA

Product: Cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MNETLGMKSGPVRHEHVFLGAEHASRERRTWFVIALCALTMLAEIAGGWRFGSLALVADGLHMSTHAGAMLIAALAYTYA
RRHAHDSRFSFGTGKLGDLAGFTSAVALALIAVLIGYEAVTRLVEPVPIRFGEAIPIAVFGLAVNLSCAWLLGGAHHGHA
HGGHDHHDGHDHAPERHQADAAHRHDHADAAAHHGAHGQQAFHARDHNFRAAYLHVIGDAVVSVLAIAGLIAARAFGWNW
MDPLAGIVGALVIANWSFVLIRDTGATLLDMTPDPALAARIRERIEGDGDAVVDLHLWRLGPGHLSAALSVATGSASRDA
RFYHQRLAGVDGLSHLTVEVMPAAAPRS

Sequences:

>Translated_348_residues
MNETLGMKSGPVRHEHVFLGAEHASRERRTWFVIALCALTMLAEIAGGWRFGSLALVADGLHMSTHAGAMLIAALAYTYA
RRHAHDSRFSFGTGKLGDLAGFTSAVALALIAVLIGYEAVTRLVEPVPIRFGEAIPIAVFGLAVNLSCAWLLGGAHHGHA
HGGHDHHDGHDHAPERHQADAAHRHDHADAAAHHGAHGQQAFHARDHNFRAAYLHVIGDAVVSVLAIAGLIAARAFGWNW
MDPLAGIVGALVIANWSFVLIRDTGATLLDMTPDPALAARIRERIEGDGDAVVDLHLWRLGPGHLSAALSVATGSASRDA
RFYHQRLAGVDGLSHLTVEVMPAAAPRS
>Mature_348_residues
MNETLGMKSGPVRHEHVFLGAEHASRERRTWFVIALCALTMLAEIAGGWRFGSLALVADGLHMSTHAGAMLIAALAYTYA
RRHAHDSRFSFGTGKLGDLAGFTSAVALALIAVLIGYEAVTRLVEPVPIRFGEAIPIAVFGLAVNLSCAWLLGGAHHGHA
HGGHDHHDGHDHAPERHQADAAHRHDHADAAAHHGAHGQQAFHARDHNFRAAYLHVIGDAVVSVLAIAGLIAARAFGWNW
MDPLAGIVGALVIANWSFVLIRDTGATLLDMTPDPALAARIRERIEGDGDAVVDLHLWRLGPGHLSAALSVATGSASRDA
RFYHQRLAGVDGLSHLTVEVMPAAAPRS

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI20070323, Length=324, Percent_Identity=27.1604938271605, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI21359890, Length=291, Percent_Identity=29.2096219931272, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI52352805, Length=298, Percent_Identity=23.1543624161074, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI222080086, Length=307, Percent_Identity=24.7557003257329, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI40255009, Length=307, Percent_Identity=24.7557003257329, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786966, Length=277, Percent_Identity=31.0469314079422, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32564488, Length=322, Percent_Identity=26.3975155279503, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193210990, Length=337, Percent_Identity=25.5192878338279, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323899, Length=344, Percent_Identity=25.8720930232558, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320411, Length=237, Percent_Identity=23.6286919831224, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24645863, Length=298, Percent_Identity=27.5167785234899, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656728, Length=338, Percent_Identity=25.7396449704142, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656724, Length=338, Percent_Identity=25.7396449704142, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656720, Length=338, Percent_Identity=25.7396449704142, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656715, Length=338, Percent_Identity=25.7396449704142, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357035, Length=338, Percent_Identity=25.7396449704142, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 37045; Mature: 37045

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETLGMKSGPVRHEHVFLGAEHASRERRTWFVIALCALTMLAEIAGGWRFGSLALVADG
CCCCCCCCCCCCCEEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
LHMSTHAGAMLIAALAYTYARRHAHDSRFSFGTGKLGDLAGFTSAVALALIAVLIGYEAV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRLVEPVPIRFGEAIPIAVFGLAVNLSCAWLLGGAHHGHAHGGHDHHDGHDHAPERHQAD
HHHHCCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHH
AAHRHDHADAAAHHGAHGQQAFHARDHNFRAAYLHVIGDAVVSVLAIAGLIAARAFGWNW
HHHHCCCHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
MDPLAGIVGALVIANWSFVLIRDTGATLLDMTPDPALAARIRERIEGDGDAVVDLHLWRL
HHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEC
GPGHLSAALSVATGSASRDARFYHQRLAGVDGLSHLTVEVMPAAAPRS
CCHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MNETLGMKSGPVRHEHVFLGAEHASRERRTWFVIALCALTMLAEIAGGWRFGSLALVADG
CCCCCCCCCCCCCEEEEEEECHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
LHMSTHAGAMLIAALAYTYARRHAHDSRFSFGTGKLGDLAGFTSAVALALIAVLIGYEAV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TRLVEPVPIRFGEAIPIAVFGLAVNLSCAWLLGGAHHGHAHGGHDHHDGHDHAPERHQAD
HHHHCCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHH
AAHRHDHADAAAHHGAHGQQAFHARDHNFRAAYLHVIGDAVVSVLAIAGLIAARAFGWNW
HHHHCCCHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
MDPLAGIVGALVIANWSFVLIRDTGATLLDMTPDPALAARIRERIEGDGDAVVDLHLWRL
HHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEEEC
GPGHLSAALSVATGSASRDARFYHQRLAGVDGLSHLTVEVMPAAAPRS
CCHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377; 9099864 [H]