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The map label for this gene is iorB [H]

Identifier: 238023785

GI number: 238023785

Start: 379003

End: 381243

Strand: Direct

Name: iorB [H]

Synonym: bglu_2g03200

Alternate gene names: 238023785

Gene position: 379003-381243 (Clockwise)

Preceding gene: 238023784

Following gene: 238023786

Centisome position: 13.4

GC content: 72.78

Gene sequence:

>2241_bases
ATGTCCTCGGGAATCATCGAAGCGAGCCGCGCCGCGCGCGCGGCCGGCGGCGACGCGACGGGCATCTCGCGGCGCCATTT
CCTGCAGGCCGGCTTCACGCTCGGCGCGGCGGCCGGCGGCGGCCTGCTGCTCGGTTTCGCGGTGCCGGCGGCAGGCGGGG
CGACGCGCCCGTCGGTGATCGGCGGTGACGCCCCCGACCAGGCGCCGGCCGGGCTCTTTGCCCCGAACGCGTTCGTGCGC
ATCGATCGCGCGGGGCAGGTCACGCTGGTGATGCCGAAGGTCGAGATGGGGCAGGGCGTCTATACGTCGATCCCGATGCT
GATCGCCGAGGAGCTCGAGGTGCCGCTCGACAGCGTGGTGCTCGACCATGCGCCGGCCGACGCGAAGCGCTACGGCGACC
CGCTGCTGGGCGGCGGCCAGCTGACCGGCGGCTCGACGTCGATCCGCTATGCCTGGGAGCCGATGCGCCGCGCCGGCGCC
ACCGCGCGCACGCTGCTGGTGGCCGCCGCCGCGCAGCAATGGAACGTCGATCCGGCATCGTGCCGCGCGGCCAACGGCGA
GGTGCTGCATGCGCCGAGCGGCCGGCGCGCGGCCTACGGCTCGCTCGTCGACGCCGCCGCGAAGCTGCCGGTGCCGGCCG
AGGTTGCGCTGAAGAAGCCCGAGGCGTTCACGCTGATCGGCAAGCCGGTGAAGCGGCTCGATTCGCCCGAGAAGGTGGAC
GGCACCGCGCGCTTCGGGCTCGACGTGCGGCTGCCGGGCATGCTGTATGCCGCGATCGTCAACAGCCCGGTGTTCGGCGG
CACCGTCGCCAGCGTCGACGACAGCGCGGCCAAGCGCGTGCCGGGCGTGCGCCAGGTGGTGCGCGTCGACAACGCGGTGG
CGGTGGTGGGCGAGCACACCTGGGCCGCCAAGCGCGGCGCCGCGGCGCTCGTGATCACGTGGCACGAAGGCGCTGGCGCC
CACGTCTCGATGGACGACATCGTCGGCGACCTCGCGCGCGCGGCCGAGCGCCCCGGCGCCGTCGCGCGCAACGACGGCGA
CGTGGCCAAGGCGCTCGGCGCGGCCAGCGCGCGCGTCGAGTCGGTCTATCAGCAGCCGTTCCTCGCGCACGCCACGATGG
AGCCGGTCAACTGCACGGTGCACGTGCGCGGCGACGGCTGCGAGATCTGGGTCGGCACGCAGGTGCCGGGCTTCGCCATC
GAGGCCGCGAAGCGCGTGACCGGCTTCGACGAGAGCCGCGTCGTGCTGCACAATCACCTGCTCGGCGGCGGCTTCGGGCG
GCGGCTGGAGACCGACATGATCGCGCAGGCGCTGAAGGTCGGCAAACAGGTGGACGCGCCCGTCAAGGTGGTCTGGACGC
GCGAGGAGGACATCCGTCACGACATGTACCGGCCGTATTACTACGACCGGATCTCGGCCGGCGTCGATGCCAACGGCAAG
CCGGTGGCGTGGCAGCACCGCATCGCCGGCTCCTCGATCATGGCGCGCTTCGCGCCCGGCGCGGTGAAGAACGGCGTGGA
CAGCGACGCGGTGGAGGTGGCCGCCGATCTGCCCTACGAGATCCCGAACCAGCGCATCGAATACGTGCGCCAGGAGCCGC
GCCACGTGCCGACCGCGTTCTGGCGCGGCGTCGGCCCGACGCGCGGCGCATTCGTGGTGGAGAGCTTCATCGACGAGCTG
GCGGTGCGCGCGAAGGCCGACCCGGTCGCCTACCGGCGCTCGCTGCTGGGCCGCACGCCGCGCGCGCGCGACGTGCTCGA
CGTGGTCGCGCGGGCGGCCGGCTGGGGGCAGGCGGTGCCCGCCGGGCGCGGCCGCGGCGTGTCGGTGCTGCACGCGTTCG
GCAGCTTCTTCAGCATGATCGCGGACGTGGCGGTGGCCGACGGCGAGGTCGTCGTCGAGCGCGTGGTCTGCGCGGTCGAT
TGCGGCATGGTCGTGAATCCCGACACGGTCGAGGCGCAGATCCAGGGCGGCATCGTGTTCGGCATCACCGCCGCCCTGTA
CGGCGAGATCACGATCCGGGACGGGCGAGTCGAGCAGAGCAACTTCACCGACTACCGGATGCTGCGCATCAACCAGACGC
CGAAGATCGACGTGCATATCGTCAAGAGCGCGCAGGCGCCGGGCGGCATCGGCGAGCCGGGCACCTCGGCGATCGCGGCG
GCGCTGGCCAACGCGATCCATGCGGCCACGGGCAAGCGCCTTTACCGGCTGCCGGTCGGCGATCAACTGAAAACGGCATG
A

Upstream 100 bases:

>100_bases
ACGCCGACATCGATGCGGCGATGGCGGGCAACATCTGCCGCTGCGGCACCTACAACCGGATTCGCGCAGCCATCAAGCTG
GCCGCGCAGGAGGCCTGACC

Downstream 100 bases:

>100_bases
GGGAGGCGGCGATGACGATTCCGAACCGGCTGCGCCGGGCATGCGGTGCGGCCGCACTGGCCGGTGCCGCGTTCGCGGCG
CCGGGCGCCCATGCGGCGGC

Product: Aerobic-type carbon monoxide dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MSSGIIEASRAARAAGGDATGISRRHFLQAGFTLGAAAGGGLLLGFAVPAAGGATRPSVIGGDAPDQAPAGLFAPNAFVR
IDRAGQVTLVMPKVEMGQGVYTSIPMLIAEELEVPLDSVVLDHAPADAKRYGDPLLGGGQLTGGSTSIRYAWEPMRRAGA
TARTLLVAAAAQQWNVDPASCRAANGEVLHAPSGRRAAYGSLVDAAAKLPVPAEVALKKPEAFTLIGKPVKRLDSPEKVD
GTARFGLDVRLPGMLYAAIVNSPVFGGTVASVDDSAAKRVPGVRQVVRVDNAVAVVGEHTWAAKRGAAALVITWHEGAGA
HVSMDDIVGDLARAAERPGAVARNDGDVAKALGAASARVESVYQQPFLAHATMEPVNCTVHVRGDGCEIWVGTQVPGFAI
EAAKRVTGFDESRVVLHNHLLGGGFGRRLETDMIAQALKVGKQVDAPVKVVWTREEDIRHDMYRPYYYDRISAGVDANGK
PVAWQHRIAGSSIMARFAPGAVKNGVDSDAVEVAADLPYEIPNQRIEYVRQEPRHVPTAFWRGVGPTRGAFVVESFIDEL
AVRAKADPVAYRRSLLGRTPRARDVLDVVARAAGWGQAVPAGRGRGVSVLHAFGSFFSMIADVAVADGEVVVERVVCAVD
CGMVVNPDTVEAQIQGGIVFGITAALYGEITIRDGRVEQSNFTDYRMLRINQTPKIDVHIVKSAQAPGGIGEPGTSAIAA
ALANAIHAATGKRLYRLPVGDQLKTA

Sequences:

>Translated_746_residues
MSSGIIEASRAARAAGGDATGISRRHFLQAGFTLGAAAGGGLLLGFAVPAAGGATRPSVIGGDAPDQAPAGLFAPNAFVR
IDRAGQVTLVMPKVEMGQGVYTSIPMLIAEELEVPLDSVVLDHAPADAKRYGDPLLGGGQLTGGSTSIRYAWEPMRRAGA
TARTLLVAAAAQQWNVDPASCRAANGEVLHAPSGRRAAYGSLVDAAAKLPVPAEVALKKPEAFTLIGKPVKRLDSPEKVD
GTARFGLDVRLPGMLYAAIVNSPVFGGTVASVDDSAAKRVPGVRQVVRVDNAVAVVGEHTWAAKRGAAALVITWHEGAGA
HVSMDDIVGDLARAAERPGAVARNDGDVAKALGAASARVESVYQQPFLAHATMEPVNCTVHVRGDGCEIWVGTQVPGFAI
EAAKRVTGFDESRVVLHNHLLGGGFGRRLETDMIAQALKVGKQVDAPVKVVWTREEDIRHDMYRPYYYDRISAGVDANGK
PVAWQHRIAGSSIMARFAPGAVKNGVDSDAVEVAADLPYEIPNQRIEYVRQEPRHVPTAFWRGVGPTRGAFVVESFIDEL
AVRAKADPVAYRRSLLGRTPRARDVLDVVARAAGWGQAVPAGRGRGVSVLHAFGSFFSMIADVAVADGEVVVERVVCAVD
CGMVVNPDTVEAQIQGGIVFGITAALYGEITIRDGRVEQSNFTDYRMLRINQTPKIDVHIVKSAQAPGGIGEPGTSAIAA
ALANAIHAATGKRLYRLPVGDQLKTA
>Mature_745_residues
SSGIIEASRAARAAGGDATGISRRHFLQAGFTLGAAAGGGLLLGFAVPAAGGATRPSVIGGDAPDQAPAGLFAPNAFVRI
DRAGQVTLVMPKVEMGQGVYTSIPMLIAEELEVPLDSVVLDHAPADAKRYGDPLLGGGQLTGGSTSIRYAWEPMRRAGAT
ARTLLVAAAAQQWNVDPASCRAANGEVLHAPSGRRAAYGSLVDAAAKLPVPAEVALKKPEAFTLIGKPVKRLDSPEKVDG
TARFGLDVRLPGMLYAAIVNSPVFGGTVASVDDSAAKRVPGVRQVVRVDNAVAVVGEHTWAAKRGAAALVITWHEGAGAH
VSMDDIVGDLARAAERPGAVARNDGDVAKALGAASARVESVYQQPFLAHATMEPVNCTVHVRGDGCEIWVGTQVPGFAIE
AAKRVTGFDESRVVLHNHLLGGGFGRRLETDMIAQALKVGKQVDAPVKVVWTREEDIRHDMYRPYYYDRISAGVDANGKP
VAWQHRIAGSSIMARFAPGAVKNGVDSDAVEVAADLPYEIPNQRIEYVRQEPRHVPTAFWRGVGPTRGAFVVESFIDELA
VRAKADPVAYRRSLLGRTPRARDVLDVVARAAGWGQAVPAGRGRGVSVLHAFGSFFSMIADVAVADGEVVVERVVCAVDC
GMVVNPDTVEAQIQGGIVFGITAALYGEITIRDGRVEQSNFTDYRMLRINQTPKIDVHIVKSAQAPGGIGEPGTSAIAAA
LANAIHAATGKRLYRLPVGDQLKTA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=384, Percent_Identity=25.5208333333333, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789230, Length=419, Percent_Identity=24.8210023866348, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 78391; Mature: 78260

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00187 TPP_ENZYMES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGIIEASRAARAAGGDATGISRRHFLQAGFTLGAAAGGGLLLGFAVPAAGGATRPSVI
CCCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCEEECCCCCCEEEEEECCCCCCCCCCCCC
GGDAPDQAPAGLFAPNAFVRIDRAGQVTLVMPKVEMGQGVYTSIPMLIAEELEVPLDSVV
CCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCHHHHH
LDHAPADAKRYGDPLLGGGQLTGGSTSIRYAWEPMRRAGATARTLLVAAAAQQWNVDPAS
CCCCCCCHHHCCCCCCCCCEECCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHCCCCHHH
CRAANGEVLHAPSGRRAAYGSLVDAAAKLPVPAEVALKKPEAFTLIGKPVKRLDSPEKVD
HCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCEEEEECCHHHHCCCCCCCC
GTARFGLDVRLPGMLYAAIVNSPVFGGTVASVDDSAAKRVPGVRQVVRVDNAVAVVGEHT
CCEEECEEEECCHHHHHHHHCCCCCCCEEECCCCHHHHHCCCHHHHHHHCCEEEEEECCH
WAAKRGAAALVITWHEGAGAHVSMDDIVGDLARAAERPGAVARNDGDVAKALGAASARVE
HHHCCCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SVYQQPFLAHATMEPVNCTVHVRGDGCEIWVGTQVPGFAIEAAKRVTGFDESRVVLHNHL
HHHHCCCHHCCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEHHH
LGGGFGRRLETDMIAQALKVGKQVDAPVKVVWTREEDIRHDMYRPYYYDRISAGVDANGK
HCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHCCCCCCCC
PVAWQHRIAGSSIMARFAPGAVKNGVDSDAVEVAADLPYEIPNQRIEYVRQEPRHVPTAF
CEEEEEHHCCHHHHHHHCCCHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHH
WRGVGPTRGAFVVESFIDELAVRAKADPVAYRRSLLGRTPRARDVLDVVARAAGWGQAVP
HCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
AGRGRGVSVLHAFGSFFSMIADVAVADGEVVVERVVCAVDCGMVVNPDTVEAQIQGGIVF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCEEE
GITAALYGEITIRDGRVEQSNFTDYRMLRINQTPKIDVHIVKSAQAPGGIGEPGTSAIAA
EEEEHHEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHH
ALANAIHAATGKRLYRLPVGDQLKTA
HHHHHHHHHCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SSGIIEASRAARAAGGDATGISRRHFLQAGFTLGAAAGGGLLLGFAVPAAGGATRPSVI
CCCCCCHHHHHHCCCCCCCCCCHHHHHHHCCEEECCCCCCEEEEEECCCCCCCCCCCCC
GGDAPDQAPAGLFAPNAFVRIDRAGQVTLVMPKVEMGQGVYTSIPMLIAEELEVPLDSVV
CCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCHHHCCCHHHHHHHHHHHHHCCCHHHHH
LDHAPADAKRYGDPLLGGGQLTGGSTSIRYAWEPMRRAGATARTLLVAAAAQQWNVDPAS
CCCCCCCHHHCCCCCCCCCEECCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHCCCCHHH
CRAANGEVLHAPSGRRAAYGSLVDAAAKLPVPAEVALKKPEAFTLIGKPVKRLDSPEKVD
HCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCEEEEECCHHHHCCCCCCCC
GTARFGLDVRLPGMLYAAIVNSPVFGGTVASVDDSAAKRVPGVRQVVRVDNAVAVVGEHT
CCEEECEEEECCHHHHHHHHCCCCCCCEEECCCCHHHHHCCCHHHHHHHCCEEEEEECCH
WAAKRGAAALVITWHEGAGAHVSMDDIVGDLARAAERPGAVARNDGDVAKALGAASARVE
HHHCCCCEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SVYQQPFLAHATMEPVNCTVHVRGDGCEIWVGTQVPGFAIEAAKRVTGFDESRVVLHNHL
HHHHCCCHHCCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEHHH
LGGGFGRRLETDMIAQALKVGKQVDAPVKVVWTREEDIRHDMYRPYYYDRISAGVDANGK
HCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCHHHHHHHCCCCCCCC
PVAWQHRIAGSSIMARFAPGAVKNGVDSDAVEVAADLPYEIPNQRIEYVRQEPRHVPTAF
CEEEEEHHCCHHHHHHHCCCHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHH
WRGVGPTRGAFVVESFIDELAVRAKADPVAYRRSLLGRTPRARDVLDVVARAAGWGQAVP
HCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCC
AGRGRGVSVLHAFGSFFSMIADVAVADGEVVVERVVCAVDCGMVVNPDTVEAQIQGGIVF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCCEEEEECCCEEE
GITAALYGEITIRDGRVEQSNFTDYRMLRINQTPKIDVHIVKSAQAPGGIGEPGTSAIAA
EEEEHHEEEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHH
ALANAIHAATGKRLYRLPVGDQLKTA
HHHHHHHHHCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]