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The map label for this gene is hom [H]

Identifier: 238023771

GI number: 238023771

Start: 355190

End: 356206

Strand: Direct

Name: hom [H]

Synonym: bglu_2g03030

Alternate gene names: 238023771

Gene position: 355190-356206 (Clockwise)

Preceding gene: 238023770

Following gene: 238023773

Centisome position: 12.56

GC content: 74.53

Gene sequence:

>1017_bases
ATGAGCCGCTGCGACGTGGTCATCTCGGGGTTCGGCGCGATCGGCCGCCGCGTCGCGCAAGCGCTCGAGGCGCGCCGGCC
GCGCTACCGCGAGCGCTACGGCGTGGACGTGCGCTTGACCGGCATCAGCCGTTCGCGCGGCGGCCTCGTCGCGCCGGACG
GGCTGCCGGCCGGCGCCGATGCGCTCGCGGCCGACGCGCTGCTCGATCCGGCGCTGAGCGGCGCCGCGTTGGTGGCCGCC
GCGCGCCCTCACGTGCTGATCGAGGCGGGGCCGACCGACTACCGCACGGGCGGTGCGGGCCTGGGCTACCTGCGCGCCGC
GCTCGGCGCCGGCGCGCACGGCATCGCGATCTCCAAGGGCGCGCTGCTGGTCGATTATCCGGGGCTGCGCGCGCTGGCCG
ACGCGAACGGCGTGATGCTGAAGATCAGCGGCGCGACCGCTGCCGCGCTGCCCACCATCGACCTGCTCGAATACAACGCT
GCCGGCTGCGAGGTGCGCGTGATGGAGGGCATTTTCACGGCCACCAGCAACTACGTGCTCGATCGGATGATGGGCGGCGC
CGCGTTCGACGCCGCGCTCGCCGATGCGCAGCGCCTCGGCATGGCCGAGCCCGACCCGCGCTGCGACGTGGACGGTTCCG
ACACCGCCTGCAAGGTCTGCATTCTCGCGAATGCCGGTTTCGGCGCGCGGCTCGCGCTCGACGCGGTCGCGCGCGAGGGA
ATCGCGCGCGTGAGCCGCGAGGATCTGGCGCGCTGGCGCGCGGCCGGCCGGGTGCCGAAGCTGGTCGGCCGCATCGAGCG
GCAGGCCGACGGCGGCGTCGGCGCGGCGGTGCGGCTGCGTACCTATGCGGCCGATCATCCGTTCGCGCGGGTGGGGGCCG
GCATGAAGGCGGTGCGGATCGAGACCGATGCGATGGGCGAACTGATCGCGTTGGGCCGCACCAGCCCGCAGGCGACGGCG
GCCGCCGCGCTCAAGGACTTCGAGCATCTGCTGATGCGCGGCGCGTTCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCAACGCGCTGGAATTCAAGGCGTTCGCCGATCTCGGCAAGCTGTTCGCGAAGTGAGCGAGCCGCCCGCCTCGCGCCGCA
GCGTGCCGTCGCAAGCCGTC

Downstream 100 bases:

>100_bases
CGGCGCGGTGCGTGGTGCGCGGACACGGCGCGGGCGCGGGCCAAGTCGCGCCCGCCGATCAGCGCAGGAGAGGGCAGGGG
GCCTGCTTCAGGCGGCGGGC

Product: Homoserine dehydrogenase

Products: NA

Alternate protein names: HDH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSRCDVVISGFGAIGRRVAQALEARRPRYRERYGVDVRLTGISRSRGGLVAPDGLPAGADALAADALLDPALSGAALVAA
ARPHVLIEAGPTDYRTGGAGLGYLRAALGAGAHGIAISKGALLVDYPGLRALADANGVMLKISGATAAALPTIDLLEYNA
AGCEVRVMEGIFTATSNYVLDRMMGGAAFDAALADAQRLGMAEPDPRCDVDGSDTACKVCILANAGFGARLALDAVAREG
IARVSREDLARWRAAGRVPKLVGRIERQADGGVGAAVRLRTYAADHPFARVGAGMKAVRIETDAMGELIALGRTSPQATA
AAALKDFEHLLMRGAFAA

Sequences:

>Translated_338_residues
MSRCDVVISGFGAIGRRVAQALEARRPRYRERYGVDVRLTGISRSRGGLVAPDGLPAGADALAADALLDPALSGAALVAA
ARPHVLIEAGPTDYRTGGAGLGYLRAALGAGAHGIAISKGALLVDYPGLRALADANGVMLKISGATAAALPTIDLLEYNA
AGCEVRVMEGIFTATSNYVLDRMMGGAAFDAALADAQRLGMAEPDPRCDVDGSDTACKVCILANAGFGARLALDAVAREG
IARVSREDLARWRAAGRVPKLVGRIERQADGGVGAAVRLRTYAADHPFARVGAGMKAVRIETDAMGELIALGRTSPQATA
AAALKDFEHLLMRGAFAA
>Mature_337_residues
SRCDVVISGFGAIGRRVAQALEARRPRYRERYGVDVRLTGISRSRGGLVAPDGLPAGADALAADALLDPALSGAALVAAA
RPHVLIEAGPTDYRTGGAGLGYLRAALGAGAHGIAISKGALLVDYPGLRALADANGVMLKISGATAAALPTIDLLEYNAA
GCEVRVMEGIFTATSNYVLDRMMGGAAFDAALADAQRLGMAEPDPRCDVDGSDTACKVCILANAGFGARLALDAVAREGI
ARVSREDLARWRAAGRVPKLVGRIERQADGGVGAAVRLRTYAADHPFARVGAGMKAVRIETDAMGELIALGRTSPQATAA
AALKDFEHLLMRGAFAA

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0460

COG function: function code E; Homoserine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homoserine dehydrogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005106
- InterPro:   IPR001342
- InterPro:   IPR019811
- InterPro:   IPR022697
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]

EC number: =1.1.1.3 [H]

Molecular weight: Translated: 34803; Mature: 34672

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS01042 HOMOSER_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRCDVVISGFGAIGRRVAQALEARRPRYRERYGVDVRLTGISRSRGGLVAPDGLPAGAD
CCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCEECCCCCCCCHH
ALAADALLDPALSGAALVAAARPHVLIEAGPTDYRTGGAGLGYLRAALGAGAHGIAISKG
HHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEECC
ALLVDYPGLRALADANGVMLKISGATAAALPTIDLLEYNAAGCEVRVMEGIFTATSNYVL
EEEEECCCCHHHCCCCCEEEEECCCCHHHCCCHHHEECCCCCCEEEEEHHHHHHHHHHHH
DRMMGGAAFDAALADAQRLGMAEPDPRCDVDGSDTACKVCILANAGFGARLALDAVAREG
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHH
IARVSREDLARWRAAGRVPKLVGRIERQADGGVGAAVRLRTYAADHPFARVGAGMKAVRI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHCCCCEEEEE
ETDAMGELIALGRTSPQATAAAALKDFEHLLMRGAFAA
EHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRCDVVISGFGAIGRRVAQALEARRPRYRERYGVDVRLTGISRSRGGLVAPDGLPAGAD
CCCEEEEECHHHHHHHHHHHHHHHCCHHHHHCCCEEEEEECCCCCCCEECCCCCCCCHH
ALAADALLDPALSGAALVAAARPHVLIEAGPTDYRTGGAGLGYLRAALGAGAHGIAISKG
HHHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEECC
ALLVDYPGLRALADANGVMLKISGATAAALPTIDLLEYNAAGCEVRVMEGIFTATSNYVL
EEEEECCCCHHHCCCCCEEEEECCCCHHHCCCHHHEECCCCCCEEEEEHHHHHHHHHHHH
DRMMGGAAFDAALADAQRLGMAEPDPRCDVDGSDTACKVCILANAGFGARLALDAVAREG
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHH
IARVSREDLARWRAAGRVPKLVGRIERQADGGVGAAVRLRTYAADHPFARVGAGMKAVRI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHCCCCEEEEE
ETDAMGELIALGRTSPQATAAAALKDFEHLLMRGAFAA
EHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]