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The map label for this gene is tcp [H]

Identifier: 238023686

GI number: 238023686

Start: 242081

End: 243724

Strand: Direct

Name: tcp [H]

Synonym: bglu_2g02090

Alternate gene names: 238023686

Gene position: 242081-243724 (Clockwise)

Preceding gene: 238023681

Following gene: 238023687

Centisome position: 8.56

GC content: 67.15

Gene sequence:

>1644_bases
ATGGAAAAAATGAAAGTTTCGACTCGCCTCGCCCTGGGCTTCGGGCTTGTGTTGTTTCTGCTCCTGCTGATTTCGGCAGC
TGCATATCGCGCCGAGCGTACGCTTGCGGTGAGCCTGTACAAAATCACTTCCGTGAACAACGTGGAGGCAAGACTGGCAA
ACCGCATGAAATCCACCGTGCGAGACCGCTCCATTGCGGTTCGCAACGTGGCGCTGTCGACCGATCCGGCCGAGCGCGAC
CAGCAGATCGCGCGTATCGACAAGCAGGACCAGGCTTACGCCGATGCGTACACGAAGCTGGCCGCGATTTTTGCGCGGGA
GCCGTCCACCACCGATCGCGAGCGGGATCTGCTCGCCAAGCTGAAGGATGACGAGGCGGTCACGAAGCCCCTATGGGCCA
AGGCGGTCGACCTGGGCAGGGCCAACGATAATGCCGGCATGATCCGGGTCTTGACGGGCGAGGCCCGTCGGCCATCCCGC
GCCTGGATCGCGCGACTCGATGAGCTGGCCGATTTCGAGGATGAGCTGAACGAACAGGCGGCCCAGGCAGCCCAGGCGAG
CTCGGAGCGCATGCAGGCGGCGACATGGACGTTCGTCGCGCTGGCATTGGCCGTCGGCTCGCTCGCCGCCTTTTTCATCA
CGCGCGGCATCCTGAGGCAATTGGGCGGCGAGCCGGCCGCGGCGCAGGAGGTGGCGCGCCGCATCGCGGCCGGCGATCTG
ACCGTGAGCCTGCAGATCGAGGAGGGCGATACGCACAGCCTGATGGCATCGCTCGAGTCGATGCGGGGGCGACTGGGTGA
AATGGTGGCGGACATCAAGGCATCGGCCGAATCGATCGCGGTTGCCGCTGGCGAAATCGCGCAAGGCAACGTCGACCTCT
CGCAGCGCACCGAGGAGCAGGCGGCCTCGCTGGAGGAAACCGCGGCGAGCATGGAGCAGTTGACCTCGGCGGTCCGGCAG
AACACCGACAACGCCCGCAAGGGCAGCTCGCTGGCCGCGAATGCGTCGGCCACGGCCACCGCCGGCGGTGATGTCGTGAA
CAGGGTGGTGTCGACGATGGAGGACATTTCCTCGAGTTCGCTGCGCGTGGCCGAGATCATCGCGGTGATCGAAGGCATCG
CGTTCCAGACCAATATCCTGGCGCTCAACGCGGCGGTGGAGGCGGCGCGAGCCGGCGAGCAGGGGCGGGGCTTCGCGGTG
GTGGCGGGCGAGGTGCGCACGCTGGCGCAGCGCAGCGCGACGGCGGCCAAGGAGATCAAGGACCTGATCAGCGCGTCGGT
GGAGCATGTGGGCACGGGCTCGCGACTGGTGCGGGAGGCGGGCTCGACGATGACCGACGTGGTGCGCTCGGTGCAGCAGG
TGACCGACATCATCGAGGAAGTGGCCTCGGCATCGACGGAGCAGGGCACGGGGATCGAGCAGGTGAACGTGGCGGTCAGT
CAAATGGACGAGGTCACGCAGCAAAACGCGGCGCTGGTGGAGCAGGCCTCGGCCTCGGCGCAAGCGCTGGCCGATCAGGC
AGGGGTGCTGCGCCAGGCGGTTGCGGTGTTTCGGATCGAGGCCGCCAAGCCGAGCCGGCAGGCGCCGGCCGCCCCGGCAC
CGAGCGCGATGCCGCGATTGAGCTGCGGCGGGCTGGCAGCGTAA

Upstream 100 bases:

>100_bases
GTTTGAAATATATACATATAAAAAATTACTAAATTTTCCAATTTTCAGGACGTAATAAAGGGGGACTCGTTGGCTCCCCT
CACCAGACTGAAGACGAAAA

Downstream 100 bases:

>100_bases
CGGTGCCGGCCGACACTTCGGCCACCTCCTAGCGCGTGCGCAATGGCGCTACGTGCTGCCGAACGTCCGGCGGTTCGAGC
GGGCGATCGGCACGGCGCGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MEKMKVSTRLALGFGLVLFLLLLISAAAYRAERTLAVSLYKITSVNNVEARLANRMKSTVRDRSIAVRNVALSTDPAERD
QQIARIDKQDQAYADAYTKLAAIFAREPSTTDRERDLLAKLKDDEAVTKPLWAKAVDLGRANDNAGMIRVLTGEARRPSR
AWIARLDELADFEDELNEQAAQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQAASLEETAASMEQLTSAVRQ
NTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSSLRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSATAAKEIKDLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGTGIEQVNVAVS
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRLSCGGLAA

Sequences:

>Translated_547_residues
MEKMKVSTRLALGFGLVLFLLLLISAAAYRAERTLAVSLYKITSVNNVEARLANRMKSTVRDRSIAVRNVALSTDPAERD
QQIARIDKQDQAYADAYTKLAAIFAREPSTTDRERDLLAKLKDDEAVTKPLWAKAVDLGRANDNAGMIRVLTGEARRPSR
AWIARLDELADFEDELNEQAAQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQAASLEETAASMEQLTSAVRQ
NTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSSLRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSATAAKEIKDLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGTGIEQVNVAVS
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRLSCGGLAA
>Mature_547_residues
MEKMKVSTRLALGFGLVLFLLLLISAAAYRAERTLAVSLYKITSVNNVEARLANRMKSTVRDRSIAVRNVALSTDPAERD
QQIARIDKQDQAYADAYTKLAAIFAREPSTTDRERDLLAKLKDDEAVTKPLWAKAVDLGRANDNAGMIRVLTGEARRPSR
AWIARLDELADFEDELNEQAAQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQAASLEETAASMEQLTSAVRQ
NTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSSLRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAV
VAGEVRTLAQRSATAAKEIKDLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGTGIEQVNVAVS
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRLSCGGLAA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=348, Percent_Identity=55.4597701149425, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1788195, Length=319, Percent_Identity=57.9937304075235, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=50.415512465374, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI1787690, Length=333, Percent_Identity=53.1531531531532, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1789453, Length=411, Percent_Identity=35.5231143552311, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57700; Mature: 57700

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKMKVSTRLALGFGLVLFLLLLISAAAYRAERTLAVSLYKITSVNNVEARLANRMKSTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHH
RDRSIAVRNVALSTDPAERDQQIARIDKQDQAYADAYTKLAAIFAREPSTTDRERDLLAK
HHHHHHHHEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LKDDEAVTKPLWAKAVDLGRANDNAGMIRVLTGEARRPSRAWIARLDELADFEDELNEQA
HCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCE
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AASLEETAASMEQLTSAVRQNTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGTGIEQVNVAVS
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SCGGLAA
CCCCCCC
>Mature Secondary Structure
MEKMKVSTRLALGFGLVLFLLLLISAAAYRAERTLAVSLYKITSVNNVEARLANRMKSTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHH
RDRSIAVRNVALSTDPAERDQQIARIDKQDQAYADAYTKLAAIFAREPSTTDRERDLLAK
HHHHHHHHEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LKDDEAVTKPLWAKAVDLGRANDNAGMIRVLTGEARRPSRAWIARLDELADFEDELNEQA
HCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQAAQASSERMQAATWTFVALALAVGSLAAFFITRGILRQLGGEPAAAQEVARRIAAGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCE
TVSLQIEEGDTHSLMASLESMRGRLGEMVADIKASAESIAVAAGEIAQGNVDLSQRTEEQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AASLEETAASMEQLTSAVRQNTDNARKGSSLAANASATATAGGDVVNRVVSTMEDISSSS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LRVAEIIAVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
DLISASVEHVGTGSRLVREAGSTMTDVVRSVQQVTDIIEEVASASTEQGTGIEQVNVAVS
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
QMDEVTQQNAALVEQASASAQALADQAGVLRQAVAVFRIEAAKPSRQAPAAPAPSAMPRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SCGGLAA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]