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The map label for this gene is rcsC [H]

Identifier: 238023653

GI number: 238023653

Start: 188400

End: 190721

Strand: Direct

Name: rcsC [H]

Synonym: bglu_2g01620

Alternate gene names: 238023653

Gene position: 188400-190721 (Clockwise)

Preceding gene: 238023652

Following gene: 238023654

Centisome position: 6.66

GC content: 64.13

Gene sequence:

>2322_bases
ATGATACCGGAGCGCAGGACCCGGCCGTCCGTTGCCGATGGTGTCGACGAGGCGTCGGAGATCGACCGCTTCGTCGTCGA
CACATGGCCGGTGGGCATGATGATCTATGCGCTTCCCAGCGGCGAGTTGCTGATCGAGAACTCTGCCGCGAAACGGCTGA
TCGACGCGGGGCAGCACGATGCGGGGCGAAGCTTCTTCGAGCGCATCGAGCCGGAGTGGGAGCGCGTGAATTGCGGGGCG
GCAGATCCGCTAGTCGAGCTCGATTGGCCGCTGTCCGCCGAGCGGACGATTCGCCTTGGCGTGACGATGTCACGGACGCG
CTACGCCGGGCAGGAGGCGCTGCTGCTCGTTGTTGCCGAGTTCAGCTGTCCCGATCGTGCCATGCCGCATCGCGAGCGGG
AAGGGGCGGCCTCGAACGCGGTGTCCGAGGTCGGAGAGCGTGAGTCGCATGCCGTGCCCAGCCTGCTGGCGGTGGTGAGC
CACGAGGTCAGGACGCCGTTGCATGGAGCGATGGGCAACCTGGAGTTGCTCGCGTACTCGCCTCTAATGCCCGAGCAACG
CGAGCGTGTCGTGACGATCCGGCACACGCTCGACGAACTGCTAGGCTTGCTCGACGATCTGCTCGAAGTCGAGCATCTGA
AGCGATTGGGGGACGATCCGCCGCTCCTGCATCTCACGCCGACCCGGCTCGACGAACTGGCTGAACATTGCGCACAAGTG
TTCGCTCCTGTCGCCCGCAGCCGCGGCTTAGCACTGTATTGCCTGACCGATCCCGCACTGGACGCGCCGGCCCAGGTCGA
TGCGCGGCGGCTGACGCGCATCCTGCACAACCTGCTCGGTAATGCAGTGAAGTTCACGAAGCGGGGCGAAATCGTGCTGT
CGGTGCATTGCCTCAATACCGTCGAGCAGCACGGTTGGGTGCGTTTCGAGGTGCGCGACACAGGCATCGGCATTCCGGCC
GAGGCGCAGGCGGCGATTTTCGAACCGCATCGACAAGCCGACGCAACAATCAGCCACCGTTTTGGCGGTAGCGGCCTGGG
CCTGTTTCTGTGCCGCCGTCTCGTCGAACTGATGGGCGGCCGCATGACGCTCGCGAGCAAGCCAGGCGAGGGCAGCGTGT
TCGGCGTGGAACTACCGGTCGCGCTGCTCGACGCACCGCGTCACGGCCAACCGCTCGCGACGAGGCGCGTCGAACTGATC
TGCGAGCATGCCGCGTGGCGTGACGCGCTGGCGCGGCGTCTTGTGGCTTGGGGCGCGACTGTCGAGGATGCGCCTCGGCT
GAGGGCGGCACCGTCCCTACGCGTGCAGGCCGGCGAGGTTCGTGACGACAGAGAATGGCCAGTTCCGCATTTCGGCACGT
TGCGCATCACGCCCGACGGGCCGCTCGCACCGCGGCGCACTGGTGATGGCGTTGAAGTGGGTCCGTTGTCGAACCGCGCG
CTCCTGCAGGCATTGATGATGCTGATTGACGGCGATGGCTGGGCTGAGCCTTCGTCGAAGCGGCAGATGAAAGCGCCGGC
CACGGTGCAAATGACGGAAGTCGTTGAAATGAAGAAAGCCGTGGCCATGGCTTCGAAGCAGGAGCAGCAAGCCCCGAACC
ACTTCCCCCCGCTCGATCTGCTGGTGATCGACGACGATGCCGTCAGCCTAACGCTGATTCGACATCAGCTAGCCACACTC
GGCCAGACAAGAGTGCGCGTCGCGCGTGACGGCCGCGAGGCGCTGACGGCGTGGAGCGAGCGGCACTTCGACGCTGTTAT
TACCGACATCGACCTGCCATGTCTGAATGGCACGGAATTGCTAGCGGTCCTGCGCAAGTACGATGAAGCGGCGATCGTCA
TCGCGATGACCGCGTTTGCTGCCGAGCACCTGGGCACGGGCTCGAGACTTTTCTCGCACGTGTTGCGCAAGCCTGCGGCG
CTGCAAGACCTGCAACGTGTGCTCAATGATGTGCAGCGCACTATACGGCCCTATGCGGTGGCCCGATCGCTAACGGACAC
TGCTGCCGCAGCGCGGGAGACGCATCGCGATTCAATGCTGCTCGTTCCGCGTGATACCTTCGCGAAAAGCTGCTCAATCA
CGCGTGCGAGGCTGGCTGCGGCAACCGCATCACACGATCGTGCAAAGCTGAAGCGCTGCCTGCATAGTTTCGAGGGCGCG
CTGTCTATCATGGGGTATGACGCTCTCGCTTCTACATGCGCGGCACTGCATGCCCAATGCGAACAAGCCGACTGGGAGAC
ACTCGAGTTGCGCTGCACGATACTGATAGCCGAGATCGAGCGGCTGGTCAGCGTTGGACCGAAAGCGGTTGAAGCCCGTT
AA

Upstream 100 bases:

>100_bases
TGCTCTACCTTGGCTTGATGCAGACAATCTTTGTTCTTGTTTGTCGTCTGCGTCGTTCTTCATACGGGGCGTCGCGCGGC
GCGGGCGCGGCGCGGGAAAC

Downstream 100 bases:

>100_bases
CAGAATTCATCAACGAATCGCGAGCAAATCACGGCGACAGCTAGGACGTGACCTCCTCGCGACTAGCCGAGCGTCCGGGG
GAGGCCGATAAAAATACATG

Product: two-component system sensor-response regulator hybrid protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MIPERRTRPSVADGVDEASEIDRFVVDTWPVGMMIYALPSGELLIENSAAKRLIDAGQHDAGRSFFERIEPEWERVNCGA
ADPLVELDWPLSAERTIRLGVTMSRTRYAGQEALLLVVAEFSCPDRAMPHREREGAASNAVSEVGERESHAVPSLLAVVS
HEVRTPLHGAMGNLELLAYSPLMPEQRERVVTIRHTLDELLGLLDDLLEVEHLKRLGDDPPLLHLTPTRLDELAEHCAQV
FAPVARSRGLALYCLTDPALDAPAQVDARRLTRILHNLLGNAVKFTKRGEIVLSVHCLNTVEQHGWVRFEVRDTGIGIPA
EAQAAIFEPHRQADATISHRFGGSGLGLFLCRRLVELMGGRMTLASKPGEGSVFGVELPVALLDAPRHGQPLATRRVELI
CEHAAWRDALARRLVAWGATVEDAPRLRAAPSLRVQAGEVRDDREWPVPHFGTLRITPDGPLAPRRTGDGVEVGPLSNRA
LLQALMMLIDGDGWAEPSSKRQMKAPATVQMTEVVEMKKAVAMASKQEQQAPNHFPPLDLLVIDDDAVSLTLIRHQLATL
GQTRVRVARDGREALTAWSERHFDAVITDIDLPCLNGTELLAVLRKYDEAAIVIAMTAFAAEHLGTGSRLFSHVLRKPAA
LQDLQRVLNDVQRTIRPYAVARSLTDTAAAARETHRDSMLLVPRDTFAKSCSITRARLAAATASHDRAKLKRCLHSFEGA
LSIMGYDALASTCAALHAQCEQADWETLELRCTILIAEIERLVSVGPKAVEAR

Sequences:

>Translated_773_residues
MIPERRTRPSVADGVDEASEIDRFVVDTWPVGMMIYALPSGELLIENSAAKRLIDAGQHDAGRSFFERIEPEWERVNCGA
ADPLVELDWPLSAERTIRLGVTMSRTRYAGQEALLLVVAEFSCPDRAMPHREREGAASNAVSEVGERESHAVPSLLAVVS
HEVRTPLHGAMGNLELLAYSPLMPEQRERVVTIRHTLDELLGLLDDLLEVEHLKRLGDDPPLLHLTPTRLDELAEHCAQV
FAPVARSRGLALYCLTDPALDAPAQVDARRLTRILHNLLGNAVKFTKRGEIVLSVHCLNTVEQHGWVRFEVRDTGIGIPA
EAQAAIFEPHRQADATISHRFGGSGLGLFLCRRLVELMGGRMTLASKPGEGSVFGVELPVALLDAPRHGQPLATRRVELI
CEHAAWRDALARRLVAWGATVEDAPRLRAAPSLRVQAGEVRDDREWPVPHFGTLRITPDGPLAPRRTGDGVEVGPLSNRA
LLQALMMLIDGDGWAEPSSKRQMKAPATVQMTEVVEMKKAVAMASKQEQQAPNHFPPLDLLVIDDDAVSLTLIRHQLATL
GQTRVRVARDGREALTAWSERHFDAVITDIDLPCLNGTELLAVLRKYDEAAIVIAMTAFAAEHLGTGSRLFSHVLRKPAA
LQDLQRVLNDVQRTIRPYAVARSLTDTAAAARETHRDSMLLVPRDTFAKSCSITRARLAAATASHDRAKLKRCLHSFEGA
LSIMGYDALASTCAALHAQCEQADWETLELRCTILIAEIERLVSVGPKAVEAR
>Mature_773_residues
MIPERRTRPSVADGVDEASEIDRFVVDTWPVGMMIYALPSGELLIENSAAKRLIDAGQHDAGRSFFERIEPEWERVNCGA
ADPLVELDWPLSAERTIRLGVTMSRTRYAGQEALLLVVAEFSCPDRAMPHREREGAASNAVSEVGERESHAVPSLLAVVS
HEVRTPLHGAMGNLELLAYSPLMPEQRERVVTIRHTLDELLGLLDDLLEVEHLKRLGDDPPLLHLTPTRLDELAEHCAQV
FAPVARSRGLALYCLTDPALDAPAQVDARRLTRILHNLLGNAVKFTKRGEIVLSVHCLNTVEQHGWVRFEVRDTGIGIPA
EAQAAIFEPHRQADATISHRFGGSGLGLFLCRRLVELMGGRMTLASKPGEGSVFGVELPVALLDAPRHGQPLATRRVELI
CEHAAWRDALARRLVAWGATVEDAPRLRAAPSLRVQAGEVRDDREWPVPHFGTLRITPDGPLAPRRTGDGVEVGPLSNRA
LLQALMMLIDGDGWAEPSSKRQMKAPATVQMTEVVEMKKAVAMASKQEQQAPNHFPPLDLLVIDDDAVSLTLIRHQLATL
GQTRVRVARDGREALTAWSERHFDAVITDIDLPCLNGTELLAVLRKYDEAAIVIAMTAFAAEHLGTGSRLFSHVLRKPAA
LQDLQRVLNDVQRTIRPYAVARSLTDTAAAARETHRDSMLLVPRDTFAKSCSITRARLAAATASHDRAKLKRCLHSFEGA
LSIMGYDALASTCAALHAQCEQADWETLELRCTILIAEIERLVSVGPKAVEAR

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=660, Percent_Identity=26.3636363636364, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1789149, Length=517, Percent_Identity=27.852998065764, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=32.3404255319149, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=34.0163934426229, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=32.7586206896552, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=30.4721030042918, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788549, Length=350, Percent_Identity=24.8571428571429, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1788393, Length=249, Percent_Identity=28.1124497991968, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=30.8695652173913, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=28.448275862069, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=76, Percent_Identity=48.6842105263158, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 84978; Mature: 84978

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPERRTRPSVADGVDEASEIDRFVVDTWPVGMMIYALPSGELLIENSAAKRLIDAGQHD
CCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEECHHHHHHHHCCCCC
AGRSFFERIEPEWERVNCGAADPLVELDWPLSAERTIRLGVTMSRTRYAGQEALLLVVAE
HHHHHHHHCCCCHHEECCCCCCCCEEECCCCCCCCEEEEEEEEHHHHHCCCCEEEEEEEE
FSCPDRAMPHREREGAASNAVSEVGERESHAVPSLLAVVSHEVRTPLHGAMGNLELLAYS
CCCCCCCCCCCHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEC
PLMPEQRERVVTIRHTLDELLGLLDDLLEVEHLKRLGDDPPLLHLTPTRLDELAEHCAQV
CCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHH
FAPVARSRGLALYCLTDPALDAPAQVDARRLTRILHNLLGNAVKFTKRGEIVLSVHCLNT
HHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEHHHH
VEQHGWVRFEVRDTGIGIPAEAQAAIFEPHRQADATISHRFGGSGLGLFLCRRLVELMGG
HHHCCEEEEEEEECCCCCCCCCCHHHCCCCHHCCCHHHHCCCCCCHHHHHHHHHHHHHCC
RMTLASKPGEGSVFGVELPVALLDAPRHGQPLATRRVELICEHAAWRDALARRLVAWGAT
CEEEECCCCCCCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VEDAPRLRAAPSLRVQAGEVRDDREWPVPHFGTLRITPDGPLAPRRTGDGVEVGPLSNRA
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCHH
LLQALMMLIDGDGWAEPSSKRQMKAPATVQMTEVVEMKKAVAMASKQEQQAPNHFPPLDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LVIDDDAVSLTLIRHQLATLGQTRVRVARDGREALTAWSERHFDAVITDIDLPCLNGTEL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECCCCCCCHHHH
LAVLRKYDEAAIVIAMTAFAAEHLGTGSRLFSHVLRKPAALQDLQRVLNDVQRTIRPYAV
HHHHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ARSLTDTAAAARETHRDSMLLVPRDTFAKSCSITRARLAAATASHDRAKLKRCLHSFEGA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LSIMGYDALASTCAALHAQCEQADWETLELRCTILIAEIERLVSVGPKAVEAR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MIPERRTRPSVADGVDEASEIDRFVVDTWPVGMMIYALPSGELLIENSAAKRLIDAGQHD
CCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCEEEECHHHHHHHHCCCCC
AGRSFFERIEPEWERVNCGAADPLVELDWPLSAERTIRLGVTMSRTRYAGQEALLLVVAE
HHHHHHHHCCCCHHEECCCCCCCCEEECCCCCCCCEEEEEEEEHHHHHCCCCEEEEEEEE
FSCPDRAMPHREREGAASNAVSEVGERESHAVPSLLAVVSHEVRTPLHGAMGNLELLAYS
CCCCCCCCCCCHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEC
PLMPEQRERVVTIRHTLDELLGLLDDLLEVEHLKRLGDDPPLLHLTPTRLDELAEHCAQV
CCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHH
FAPVARSRGLALYCLTDPALDAPAQVDARRLTRILHNLLGNAVKFTKRGEIVLSVHCLNT
HHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEHHHH
VEQHGWVRFEVRDTGIGIPAEAQAAIFEPHRQADATISHRFGGSGLGLFLCRRLVELMGG
HHHCCEEEEEEEECCCCCCCCCCHHHCCCCHHCCCHHHHCCCCCCHHHHHHHHHHHHHCC
RMTLASKPGEGSVFGVELPVALLDAPRHGQPLATRRVELICEHAAWRDALARRLVAWGAT
CEEEECCCCCCCEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VEDAPRLRAAPSLRVQAGEVRDDREWPVPHFGTLRITPDGPLAPRRTGDGVEVGPLSNRA
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCHH
LLQALMMLIDGDGWAEPSSKRQMKAPATVQMTEVVEMKKAVAMASKQEQQAPNHFPPLDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LVIDDDAVSLTLIRHQLATLGQTRVRVARDGREALTAWSERHFDAVITDIDLPCLNGTEL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECCCCCCCHHHH
LAVLRKYDEAAIVIAMTAFAAEHLGTGSRLFSHVLRKPAALQDLQRVLNDVQRTIRPYAV
HHHHHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ARSLTDTAAAARETHRDSMLLVPRDTFAKSCSITRARLAAATASHDRAKLKRCLHSFEGA
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
LSIMGYDALASTCAALHAQCEQADWETLELRCTILIAEIERLVSVGPKAVEAR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]