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The map label for this gene is fnr [H]

Identifier: 238023552

GI number: 238023552

Start: 56532

End: 57281

Strand: Reverse

Name: fnr [H]

Synonym: bglu_2g00530

Alternate gene names: 238023552

Gene position: 57281-56532 (Counterclockwise)

Preceding gene: 238023553

Following gene: 238023550

Centisome position: 2.03

GC content: 67.6

Gene sequence:

>750_bases
ATGTTGATTCCTGTAGCCCAACGTTCCTCCCGCCCCACCCGCTCCTCCAGCTCCTGGGCACCCCATCCCGCCGCGCATTG
CTCCACCTGTTCGATGCGCCACCTCTGCATGCCGCAAGGCCTCAATAGCGAGGCCATCGAGCGGCTCGAATCGGTGATCT
GCGCGGCGCGCCCCGTGCGCCGCGGCGAAGCGCTGTTCCGCGAAGGCGACGAGTTCGACAACCTCTACGCCGTGCGCTCC
GGCTCGCTCAAGACCATCGCCACGCGTCAGGACGGCCGCGAGCAAGTGGCAGGCCTCCATCTGGCCGGCGAGGCGCTCGG
CTTCGACGGCATCTGCGACAGCCACCATCCGCGCACCGCGGTCGCGCTCGAGGACAGCACCGTCTGCGTGATTCCCTACG
GCTCGCTGCGCTCGCTGTGCTCCGAGGCCAGCACGCTGCAGGCGCGCGTGCTGAAGCTGATGAGCGAGCAGATCGTGCGC
GAGACGACGCAGGCCATCTTGCTCGGGTCGCTGAACGCCGACGAGCGCGTCGCCTCGTTCCTGCTCGACGTCTCGGCGCG
CTACATGGTGCGCGGCTATTCGGCCACCGAATTCAACCTGCGCATGACGCGCGAGGACATCGGCAGCTACCTGGGCATCA
CGCTCGAAACGGTCAGCCGCACGCTGTCGAAGTTCCAGCGGCAGGGCCTGCTCGTCATGCAGGGGCGCGTCGTGCGCGTG
CTCGATTTCGACGGACTGCGCAAGATCTGA

Upstream 100 bases:

>100_bases
CGAAGCATTCCTCAAACTTGGCTGCTCGATCATCTGTTGGAACATCTTCAGACGAGCTGAGCAGGGTTTTTGAACTGGCC
TCTAAGTGTGAGTACGCATC

Downstream 100 bases:

>100_bases
TGGTTCCGTTATCGAAGGGTCCGATGCGCGGCTCGATCCCGCCTTCGACTCAGGACCCCACTGCCACTGCCCAGCGAGGC
CCGACGCCTGTCGGCCCTGC

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLIPVAQRSSRPTRSSSSWAPHPAAHCSTCSMRHLCMPQGLNSEAIERLESVICAARPVRRGEALFREGDEFDNLYAVRS
GSLKTIATRQDGREQVAGLHLAGEALGFDGICDSHHPRTAVALEDSTVCVIPYGSLRSLCSEASTLQARVLKLMSEQIVR
ETTQAILLGSLNADERVASFLLDVSARYMVRGYSATEFNLRMTREDIGSYLGITLETVSRTLSKFQRQGLLVMQGRVVRV
LDFDGLRKI

Sequences:

>Translated_249_residues
MLIPVAQRSSRPTRSSSSWAPHPAAHCSTCSMRHLCMPQGLNSEAIERLESVICAARPVRRGEALFREGDEFDNLYAVRS
GSLKTIATRQDGREQVAGLHLAGEALGFDGICDSHHPRTAVALEDSTVCVIPYGSLRSLCSEASTLQARVLKLMSEQIVR
ETTQAILLGSLNADERVASFLLDVSARYMVRGYSATEFNLRMTREDIGSYLGITLETVSRTLSKFQRQGLLVMQGRVVRV
LDFDGLRKI
>Mature_249_residues
MLIPVAQRSSRPTRSSSSWAPHPAAHCSTCSMRHLCMPQGLNSEAIERLESVICAARPVRRGEALFREGDEFDNLYAVRS
GSLKTIATRQDGREQVAGLHLAGEALGFDGICDSHHPRTAVALEDSTVCVIPYGSLRSLCSEASTLQARVLKLMSEQIVR
ETTQAILLGSLNADERVASFLLDVSARYMVRGYSATEFNLRMTREDIGSYLGITLETVSRTLSKFQRQGLLVMQGRVVRV
LDFDGLRKI

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=42.0353982300885, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27458; Mature: 27458

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIPVAQRSSRPTRSSSSWAPHPAAHCSTCSMRHLCMPQGLNSEAIERLESVICAARPVR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCH
RGEALFREGDEFDNLYAVRSGSLKTIATRQDGREQVAGLHLAGEALGFDGICDSHHPRTA
HHHHHHHCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHCCHHHCCCCCCCCCCCCCEE
VALEDSTVCVIPYGSLRSLCSEASTLQARVLKLMSEQIVRETTQAILLGSLNADERVASF
EEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLDVSARYMVRGYSATEFNLRMTREDIGSYLGITLETVSRTLSKFQRQGLLVMQGRVVRV
HHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEE
LDFDGLRKI
EECCCCCCC
>Mature Secondary Structure
MLIPVAQRSSRPTRSSSSWAPHPAAHCSTCSMRHLCMPQGLNSEAIERLESVICAARPVR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCH
RGEALFREGDEFDNLYAVRSGSLKTIATRQDGREQVAGLHLAGEALGFDGICDSHHPRTA
HHHHHHHCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHCCHHHCCCCCCCCCCCCCEE
VALEDSTVCVIPYGSLRSLCSEASTLQARVLKLMSEQIVRETTQAILLGSLNADERVASF
EEECCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLDVSARYMVRGYSATEFNLRMTREDIGSYLGITLETVSRTLSKFQRQGLLVMQGRVVRV
HHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEE
LDFDGLRKI
EECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]