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The map label for this gene is emrK [H]

Identifier: 238023531

GI number: 238023531

Start: 34300

End: 35790

Strand: Direct

Name: emrK [H]

Synonym: bglu_2g00320

Alternate gene names: 238023531

Gene position: 34300-35790 (Clockwise)

Preceding gene: 238023524

Following gene: 238023532

Centisome position: 1.21

GC content: 73.64

Gene sequence:

>1491_bases
ATGTCCGATGTCACCGAGTTCCCGTTGCCGTCCGCCGTGCGAGGCCGGCGCGCGCCGATCCGCCGCGTGCCGCGGCGCCT
GGCCGACGCGCTGCACGGCAGGTTCGTGCCGCGGCGCGCGCGTGCCGCGGACGACGATCCGCCGCCGCGCCCGTCGGACG
ACCCGTCCGGCGACGCCGCGACGCGCGCGAGCGGCGCGACGGACCCGCAGCAGGACCCGCAGCAGGACCCGCAGCAGGAC
CCGCAGCAGGACCCGCAGCAGGACCCGCAGCAGGGCTCGCGGCACCCGGGCCGGCGCGCAGCGGATTCGAACGATGGCGG
CGGGCGCCGCGATCGTTCTCGCGAAGGCGGGGACGGCGGTGACGGCCGCGACGGCAGGCGCGGCGGCGGGGATGGCGATG
ACGGAGATGGCGGTGACGCCGATCGCGACGGCAAGCCCGACGACCGCAAGCGCAAGGGCTCGAACCGCAAGACGCTGATC
ATCCTCGCCATCGTGGCGGTGCTGCTGCTGATCGTGGCGCTGGTCTGGTGGCTGCTCACGCGCAACCAGGTCAGCACCGA
CGACGCCTACACCGACGGCAACGCGATCGCGATCGCGCCGCATGTCTCGGGCTACGTGACGCGCCTGAACGTCGACGACA
ACACCTACGTCCACCGCGGCGACCTGCTGGTGCAGATCGATCCGCGCGACTACCAGGCCCAGCTCGACGCGGCCGACGCG
CAGCTCGGCCTCGCGCAGGCGCAGCTCGACGCGGCGCGCGTGCAGCTCGACATCGCGCGCGTGCAGTATCCGGCCCAGTA
CGCGCAGGCCCGCGCCCAGATCGAATCGGCCGAGGCCGCCTACCAGCAGGCGCTCGCCGCGCAGCAGCGGCAGCACGCGG
TGGATGCGCGGGCCACCTCGAAGCAGGCGATCGACGCGGCCGACGCGCAGCGCGCCAGCGCCGACGCGAACGTGGCGATG
GCGCGCGCCCAGGCCCGCACGGCCGCGCTCGTGCCGCAGCAGATCCGCACCGTGGAGAGCACCCTCGAGGAGCGCCGCCA
GCAGGTGCTGGCCGCGCGCGCGCAGCGCGAGACGGCCGCGCTGAACCTGTCGTACTGCGCGATCCGCGCGCCGTCCGACG
GCTGGGTCACGCGCCGCAACGTGCAGCTCGGCTCGTTCCTGCAAACCGGCAGCTCGCTGTTCTCGATCGTCACGCCGCGC
ATCTGGATCACCGCGAACTTCAAGGAGTCGCAGCTCGAGCGCATGCGTATCGGCGACCGCGTGGACGTGTCGGTGGACGC
CTATCCCGAGCTCGCGCTGCACGGCCACGTCGACAGCGTCCAGCTCGGCAGCGGCTCGCGCTTCTCGGCGTTCCCGGCCG
AGAACGCCACCGGCAACTTCGTGAAGATCGTGCAGCGCGTGCCGGTGAAGATCGTGCTCGACGGCCCGCTGCCGACCAAC
CCGCCGCTCGGCCTCGGCCTGTCGGCCGTGCCCACCGTTCACCTGCCGTGA

Upstream 100 bases:

>100_bases
CGGCGCGCGGCGCGCAGGCAGGCTCGATCCTTGCTCCGCTGCCCCCGATGCGAATTCGCACATGACCGTGCGAGATGCGA
TCCAGACTGGAGCCCACGCG

Downstream 100 bases:

>100_bases
TGCGCCGCCCCGCCATGGCCCACTTCGCGGCACCGCCGCCTGGGAGCGAACCGATGTCCGTGCCGTTGCCGTTGTCGCCC
GCGCCGCGCGCGGGCCGCCG

Product: Secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSDVTEFPLPSAVRGRRAPIRRVPRRLADALHGRFVPRRARAADDDPPPRPSDDPSGDAATRASGATDPQQDPQQDPQQD
PQQDPQQDPQQGSRHPGRRAADSNDGGGRRDRSREGGDGGDGRDGRRGGGDGDDGDGGDADRDGKPDDRKRKGSNRKTLI
ILAIVAVLLLIVALVWWLLTRNQVSTDDAYTDGNAIAIAPHVSGYVTRLNVDDNTYVHRGDLLVQIDPRDYQAQLDAADA
QLGLAQAQLDAARVQLDIARVQYPAQYAQARAQIESAEAAYQQALAAQQRQHAVDARATSKQAIDAADAQRASADANVAM
ARAQARTAALVPQQIRTVESTLEERRQQVLAARAQRETAALNLSYCAIRAPSDGWVTRRNVQLGSFLQTGSSLFSIVTPR
IWITANFKESQLERMRIGDRVDVSVDAYPELALHGHVDSVQLGSGSRFSAFPAENATGNFVKIVQRVPVKIVLDGPLPTN
PPLGLGLSAVPTVHLP

Sequences:

>Translated_496_residues
MSDVTEFPLPSAVRGRRAPIRRVPRRLADALHGRFVPRRARAADDDPPPRPSDDPSGDAATRASGATDPQQDPQQDPQQD
PQQDPQQDPQQGSRHPGRRAADSNDGGGRRDRSREGGDGGDGRDGRRGGGDGDDGDGGDADRDGKPDDRKRKGSNRKTLI
ILAIVAVLLLIVALVWWLLTRNQVSTDDAYTDGNAIAIAPHVSGYVTRLNVDDNTYVHRGDLLVQIDPRDYQAQLDAADA
QLGLAQAQLDAARVQLDIARVQYPAQYAQARAQIESAEAAYQQALAAQQRQHAVDARATSKQAIDAADAQRASADANVAM
ARAQARTAALVPQQIRTVESTLEERRQQVLAARAQRETAALNLSYCAIRAPSDGWVTRRNVQLGSFLQTGSSLFSIVTPR
IWITANFKESQLERMRIGDRVDVSVDAYPELALHGHVDSVQLGSGSRFSAFPAENATGNFVKIVQRVPVKIVLDGPLPTN
PPLGLGLSAVPTVHLP
>Mature_495_residues
SDVTEFPLPSAVRGRRAPIRRVPRRLADALHGRFVPRRARAADDDPPPRPSDDPSGDAATRASGATDPQQDPQQDPQQDP
QQDPQQDPQQGSRHPGRRAADSNDGGGRRDRSREGGDGGDGRDGRRGGGDGDDGDGGDADRDGKPDDRKRKGSNRKTLII
LAIVAVLLLIVALVWWLLTRNQVSTDDAYTDGNAIAIAPHVSGYVTRLNVDDNTYVHRGDLLVQIDPRDYQAQLDAADAQ
LGLAQAQLDAARVQLDIARVQYPAQYAQARAQIESAEAAYQQALAAQQRQHAVDARATSKQAIDAADAQRASADANVAMA
RAQARTAALVPQQIRTVESTLEERRQQVLAARAQRETAALNLSYCAIRAPSDGWVTRRNVQLGSFLQTGSSLFSIVTPRI
WITANFKESQLERMRIGDRVDVSVDAYPELALHGHVDSVQLGSGSRFSAFPAENATGNFVKIVQRVPVKIVLDGPLPTNP
PLGLGLSAVPTVHLP

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=355, Percent_Identity=35.4929577464789, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789041, Length=360, Percent_Identity=32.5, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1790519, Length=319, Percent_Identity=31.3479623824451, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789637, Length=353, Percent_Identity=27.7620396600567, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790024, Length=290, Percent_Identity=29.6551724137931, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081951, Length=323, Percent_Identity=28.1733746130031, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790012, Length=276, Percent_Identity=25.7246376811594, Blast_Score=72, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 53576; Mature: 53445

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVTEFPLPSAVRGRRAPIRRVPRRLADALHGRFVPRRARAADDDPPPRPSDDPSGDAA
CCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCH
TRASGATDPQQDPQQDPQQDPQQDPQQDPQQGSRHPGRRAADSNDGGGRRDRSREGGDGG
HCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGRDGRRGGGDGDDGDGGDADRDGKPDDRKRKGSNRKTLIILAIVAVLLLIVALVWWLLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHC
RNQVSTDDAYTDGNAIAIAPHVSGYVTRLNVDDNTYVHRGDLLVQIDPRDYQAQLDAADA
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEECCEEEEECCCCHHHHHCHHHH
QLGLAQAQLDAARVQLDIARVQYPAQYAQARAQIESAEAAYQQALAAQQRQHAVDARATS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQAIDAADAQRASADANVAMARAQARTAALVPQQIRTVESTLEERRQQVLAARAQRETAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LNLSYCAIRAPSDGWVTRRNVQLGSFLQTGSSLFSIVTPRIWITANFKESQLERMRIGDR
EEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCC
VDVSVDAYPELALHGHVDSVQLGSGSRFSAFPAENATGNFVKIVQRVPVKIVLDGPLPTN
EEEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCC
PPLGLGLSAVPTVHLP
CCCCCCCCCCCEEECC
>Mature Secondary Structure 
SDVTEFPLPSAVRGRRAPIRRVPRRLADALHGRFVPRRARAADDDPPPRPSDDPSGDAA
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCH
TRASGATDPQQDPQQDPQQDPQQDPQQDPQQGSRHPGRRAADSNDGGGRRDRSREGGDGG
HCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DGRDGRRGGGDGDDGDGGDADRDGKPDDRKRKGSNRKTLIILAIVAVLLLIVALVWWLLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHC
RNQVSTDDAYTDGNAIAIAPHVSGYVTRLNVDDNTYVHRGDLLVQIDPRDYQAQLDAADA
CCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCEEEECCEEEEECCCCHHHHHCHHHH
QLGLAQAQLDAARVQLDIARVQYPAQYAQARAQIESAEAAYQQALAAQQRQHAVDARATS
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQAIDAADAQRASADANVAMARAQARTAALVPQQIRTVESTLEERRQQVLAARAQRETAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
LNLSYCAIRAPSDGWVTRRNVQLGSFLQTGSSLFSIVTPRIWITANFKESQLERMRIGDR
EEEEEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCC
VDVSVDAYPELALHGHVDSVQLGSGSRFSAFPAENATGNFVKIVQRVPVKIVLDGPLPTN
EEEEECCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCC
PPLGLGLSAVPTVHLP
CCCCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]