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The map label for this gene is xanP [H]

Identifier: 238023528

GI number: 238023528

Start: 28195

End: 29565

Strand: Reverse

Name: xanP [H]

Synonym: bglu_2g00280

Alternate gene names: 238023528

Gene position: 29565-28195 (Counterclockwise)

Preceding gene: 238023529

Following gene: 238023527

Centisome position: 1.05

GC content: 70.24

Gene sequence:

>1371_bases
ATGTCATCGATCCAGCCCGACCGCACCGCCCCCGCCGCCGTCCCCGATCTGGTCTACGGCCCCGACGACCGCCCCGCGCC
CGCCATCGCGTTCGTCGCCGCGCTCCAGCACCTGCTCGCAATCCTGGTGCCGATCGTCACGCCGGGCCTGCTGATCTGCC
AGGCGCTCGCCGTGCCGAGCCGCGACACCACGCTGATCGTGTCGATGTCGCTGGTGATCTCGGGCATCGCCACCTTCCTG
CAGTGCCGCCGCTTCGGCCCGCTCGGCGCCGGCCTGCTGATCGTGCAGGGCACCAGCTTCAATTTCGTCGGCCCGCTGAT
CGCGGGCGGCAGCCTGATGGTCAAGCAGGGCACGCCGGTGGCCACCGTGATGGCGGCGATCTTCGGCACGGTGATCGCCG
GCTCGTTCGTGGAGATGGCCGTGTCGCGCGTGCTGCCGTTCGTCAAGCGCCTCATCACGCCGCTCGTGACCGGCATCGTG
GTGCTGCTGATCGGCCTCACGCTGATCAAGGTCGGCCTCGTCAGCATGGGCGGCGGCTACGGCGCGATGGCCAACGGCAG
TTTCGCGAGCGCGCAGAACCTGATGCTGTCCGGGCTCGTGCTCGGCACGATCGTCGTGCTGAACCGCGTGCCGGTGGTCT
GGGTGCGCAGCACCGCGCTCGTGATCGCGCTCGCGCTCGGCTATCTGGCGGCCGGCGCGGCGGGCCGGCTCGACTTCACC
GGCGCGCGCGAGGCGGCGCTGTTCCAGATCCCCACGCCGCTGCATTTCGGGCTCGGCTTCTCGTGGTCGCTGTTCGTGCC
GATGCTGGTGATCTACCTCGTCACCTCGCTCGAGGCGATCGGCGACGTCACCGCCACCAGCAAGGTATCGCGCGAGCCGG
TGGAAGGGCCGCTGTGGATGCGCCGCATCAAGGGCGGGGTGCTCGTCAACGGTGCCAACTCGCTGCTGGCCGGCGTGTTC
AATACGTTTCCGAGTTCGGTGTTCGCGCAGAACAACGGCGTGATCCAGCTCACCGGCATCGCGAGCCGGCACGTCGGGCT
CTGGATCGCCGGCATGCTGGTGGTGCTCGGGCTGTTTCCGGTCGTGGCCGGCGTGCTGCAGGCGGTGCCCGAGCCCGTGC
TCGGCGGCGCCGCGATGGTGATGTTCGGCGCGGTGGCCGCCTCGGGCATCAACATCCTGGCCGGCGTGAAGCTCGACCGC
CGCGCGCTGCTGATCGTGGCCGTGTCGCTGGCGCTCGGGCTCGGCGTCTCGCAGGTGCCGGAGATCCTCACCCACCTGCC
GAGCGCGCTGAAGAACGTGCTGGCCTCGGGCGTCGCCACCGGCGGGGTCTGCGCGCTCGTGATGAACTGGTTCCTGCCCG
AGCAGGACTAG

Upstream 100 bases:

>100_bases
CCCGCGGTGCCCGGGGCGGGCTGCGCGCCGCTTTTTTGGCGCGCGGCCCAGCCGGTAAAATCCTCCGCTTCCCCTTCGCC
ACCGCCCCGGCCTTCCCGCG

Downstream 100 bases:

>100_bases
GCAGCGCCCGCCCGCCTGTCAGGTCAGGCAAGGCGGCGCGCCGGCCCTGCTTCGCCCGCAGGCCGGCCAGGGCCGGGCCC
GTCGAGGGCAGCAACGCGTT

Product: Xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSSIQPDRTAPAAVPDLVYGPDDRPAPAIAFVAALQHLLAILVPIVTPGLLICQALAVPSRDTTLIVSMSLVISGIATFL
QCRRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPVATVMAAIFGTVIAGSFVEMAVSRVLPFVKRLITPLVTGIV
VLLIGLTLIKVGLVSMGGGYGAMANGSFASAQNLMLSGLVLGTIVVLNRVPVVWVRSTALVIALALGYLAAGAAGRLDFT
GAREAALFQIPTPLHFGLGFSWSLFVPMLVIYLVTSLEAIGDVTATSKVSREPVEGPLWMRRIKGGVLVNGANSLLAGVF
NTFPSSVFAQNNGVIQLTGIASRHVGLWIAGMLVVLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGVKLDR
RALLIVAVSLALGLGVSQVPEILTHLPSALKNVLASGVATGGVCALVMNWFLPEQD

Sequences:

>Translated_456_residues
MSSIQPDRTAPAAVPDLVYGPDDRPAPAIAFVAALQHLLAILVPIVTPGLLICQALAVPSRDTTLIVSMSLVISGIATFL
QCRRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPVATVMAAIFGTVIAGSFVEMAVSRVLPFVKRLITPLVTGIV
VLLIGLTLIKVGLVSMGGGYGAMANGSFASAQNLMLSGLVLGTIVVLNRVPVVWVRSTALVIALALGYLAAGAAGRLDFT
GAREAALFQIPTPLHFGLGFSWSLFVPMLVIYLVTSLEAIGDVTATSKVSREPVEGPLWMRRIKGGVLVNGANSLLAGVF
NTFPSSVFAQNNGVIQLTGIASRHVGLWIAGMLVVLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGVKLDR
RALLIVAVSLALGLGVSQVPEILTHLPSALKNVLASGVATGGVCALVMNWFLPEQD
>Mature_455_residues
SSIQPDRTAPAAVPDLVYGPDDRPAPAIAFVAALQHLLAILVPIVTPGLLICQALAVPSRDTTLIVSMSLVISGIATFLQ
CRRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPVATVMAAIFGTVIAGSFVEMAVSRVLPFVKRLITPLVTGIVV
LLIGLTLIKVGLVSMGGGYGAMANGSFASAQNLMLSGLVLGTIVVLNRVPVVWVRSTALVIALALGYLAAGAAGRLDFTG
AREAALFQIPTPLHFGLGFSWSLFVPMLVIYLVTSLEAIGDVTATSKVSREPVEGPLWMRRIKGGVLVNGANSLLAGVFN
TFPSSVFAQNNGVIQLTGIASRHVGLWIAGMLVVLGLFPVVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGVKLDRR
ALLIVAVSLALGLGVSQVPEILTHLPSALKNVLASGVATGGVCALVMNWFLPEQD

Specific function: Specific, proton motive force-dependent high-affinity transporter for xanthine [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=510, Percent_Identity=23.3333333333333, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI40316845, Length=510, Percent_Identity=23.3333333333333, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI44680145, Length=466, Percent_Identity=23.3905579399142, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI44680143, Length=470, Percent_Identity=23.1914893617021, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790087, Length=459, Percent_Identity=53.1590413943355, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI87082178, Length=438, Percent_Identity=43.8356164383562, Blast_Score=345, Evalue=5e-96,
Organism=Escherichia coli, GI87082181, Length=443, Percent_Identity=29.7968397291196, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788843, Length=203, Percent_Identity=26.6009852216749, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081818, Length=414, Percent_Identity=26.8115942028986, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17558856, Length=410, Percent_Identity=25.1219512195122, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46873; Mature: 46742

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00879 ODR_DC_2_2 ; PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIQPDRTAPAAVPDLVYGPDDRPAPAIAFVAALQHLLAILVPIVTPGLLICQALAVPS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
RDTTLIVSMSLVISGIATFLQCRRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPV
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCCEEEECCCCH
ATVMAAIFGTVIAGSFVEMAVSRVLPFVKRLITPLVTGIVVLLIGLTLIKVGLVSMGGGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAMANGSFASAQNLMLSGLVLGTIVVLNRVPVVWVRSTALVIALALGYLAAGAAGRLDFT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCC
GAREAALFQIPTPLHFGLGFSWSLFVPMLVIYLVTSLEAIGDVTATSKVSREPVEGPLWM
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHH
RRIKGGVLVNGANSLLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGLWIAGMLVVLGLFP
HHHCCCEEEECHHHHHHHHHHHCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGVKLDRRALLIVAVSLALGLGVSQVP
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHH
EILTHLPSALKNVLASGVATGGVCALVMNWFLPEQD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SSIQPDRTAPAAVPDLVYGPDDRPAPAIAFVAALQHLLAILVPIVTPGLLICQALAVPS
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
RDTTLIVSMSLVISGIATFLQCRRFGPLGAGLLIVQGTSFNFVGPLIAGGSLMVKQGTPV
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCCEEEECCCCH
ATVMAAIFGTVIAGSFVEMAVSRVLPFVKRLITPLVTGIVVLLIGLTLIKVGLVSMGGGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAMANGSFASAQNLMLSGLVLGTIVVLNRVPVVWVRSTALVIALALGYLAAGAAGRLDFT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCC
GAREAALFQIPTPLHFGLGFSWSLFVPMLVIYLVTSLEAIGDVTATSKVSREPVEGPLWM
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHH
RRIKGGVLVNGANSLLAGVFNTFPSSVFAQNNGVIQLTGIASRHVGLWIAGMLVVLGLFP
HHHCCCEEEECHHHHHHHHHHHCCHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
VVAGVLQAVPEPVLGGAAMVMFGAVAASGINILAGVKLDRRALLIVAVSLALGLGVSQVP
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCHHHHH
EILTHLPSALKNVLASGVATGGVCALVMNWFLPEQD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]