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The map label for this gene is cidA [H]

Identifier: 237814417

GI number: 237814417

Start: 4038038

End: 4038445

Strand: Direct

Name: cidA [H]

Synonym: GBP346_A4215

Alternate gene names: 237814417

Gene position: 4038038-4038445 (Clockwise)

Preceding gene: 237814415

Following gene: 237814418

Centisome position: 98.52

GC content: 75.98

Gene sequence:

>408_bases
GTGGGCCGCGCGGCGCGCGTCGCGTTGCAGACGGCCGCGCTCGGCGCGCTGTGGGCGGCGATCGACTGGACGGTGCGCGC
GTTCGGCGTGCCGGTGCCGTCCGGCGTGGTCGGCCTCGCGGTGCTGCTCGCGCTGCTGCTGTCCGGCCGCGTCGCGCCCG
GCTGGGTGAAGGACGGCGCGAACTGGCTGCTGTCCGACATGCTGCTCTTCTTCATCCCGGCGACCGTCGCGGCCGTGCAG
TACGGCGGCCTCTTCAAGGCGGACGGCTGGCGGCTCGCGCTCGTCGTCGTCGCCGGAACCACGTTCGTGATGCTGTCGGT
GGCGATCGCGGTCGACGTCGCGGCGGGCTTCGAGCGGCGGCTCGCGGTGATGCGCGTGCGTGCCGGCCGCCGCCGCGCGC
GGGCCTGA

Upstream 100 bases:

>100_bases
CTCCATTCTGTAAAGCAAGGCATTTCGGGAGCATTCGATGAGCAGGATTTCGGCTACGGCGGCAACCGCGACTCGCCCGA
CGACGGCGGCGCCCGCGCGC

Downstream 100 bases:

>100_bases
CGCCGCACGGTTTCCCCTTTCCCCATTTCATGCCATTCGTTGATGGCACCGGTTCTGAAGGCCGCATCATGACGACGCCC
GATCTCTCGTTTCTCACCGC

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDGANWLLSDMLLFFIPATVAAVQ
YGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA

Sequences:

>Translated_135_residues
MGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDGANWLLSDMLLFFIPATVAAVQ
YGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA
>Mature_134_residues
GRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDGANWLLSDMLLFFIPATVAAVQY
GGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERRLAVMRVRAGRRRARA

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 14201; Mature: 14070

Theoretical pI: Translated: 12.31; Mature: 12.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCH
NWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERR
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LAVMRVRAGRRRARA
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRAARVALQTAALGALWAAIDWTVRAFGVPVPSGVVGLAVLLALLLSGRVAPGWVKDGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCH
NWLLSDMLLFFIPATVAAVQYGGLFKADGWRLALVVVAGTTFVMLSVAIAVDVAAGFERR
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
LAVMRVRAGRRRARA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA