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The map label for this gene is ywbI [H]

Identifier: 237814416

GI number: 237814416

Start: 4036912

End: 4037835

Strand: Reverse

Name: ywbI [H]

Synonym: GBP346_A4214

Alternate gene names: 237814416

Gene position: 4037835-4036912 (Counterclockwise)

Preceding gene: 237814419

Following gene: 237814413

Centisome position: 98.52

GC content: 70.67

Gene sequence:

>924_bases
ATGGAGCTGCGCGCGTTGCGGTATTTCGTCGAGGTCGTCAGGCAGCAGAGCTTCACCGTCGCGGCCGAGCAGATGCACGT
CACGCAGCCGACGATCAGCAAGATGGTGAAGGCGCTCGAGGACGAAATCGGCTCGCCGCTGCTGCTGCGCGACGGTCGCC
AGATGGTGCTCACGGATGCCGGCCGGATCGTCTATCAGCGCGGCCAGGACGTGCTCGCCGCGCAGGCGCAGCTTCAGGCC
GAGCTGAACGATCTCGGCACGCTCGGGCGCGGCGAGCTGACGATCGGGATTCCGCCGCTCGGCGGTTCGCTGTTCACGCC
GGCGATCGCCGCGTTCAAGGAGCGCTATCCGCGCATCGAGCTGAAGCTGTTCGAGCAGGGCGCGCGGATGATCGAAGAGG
CGCTCGTCGCGGGCGAGCTGGAGCTCGGCGGCGTGCTCGAGCCCGTCGATCCGGCCGTGTTCGACGTGCTGCCGATGGTG
CGCGCGCCGCTGTGGCTCGTCGCGCCGCACGCGTCGCGCTGGGACGGCGACGCGACGGTGCCGCTCGCCGACCTGGCCGA
CGAGCCGTTCGTGTTCTACGCCGAAAGCCTGGCGCTGCACGACGCGGTGCTCGATGCGTGCCGCAAGGTCGGCTTCACGC
CGCAGATCGTGAGCCGCAGCGGCCATTGGGATTTCATGGCGGCGCTCGTGCACGCGGGCGTCGGCATCGCGCTGCTGCCC
GAGCCGTATTGCCGGCGGCTCGACACCGCGCGGTTCACGTGCCGGCCGATCGTCGAGCCCGAGATCACCTGGGCGGTCGC
GATCGGCTGGCTCAAGAGGGGATATCTGTCGCACGCCGCGCGCGCGTGGCTCGACGTCGCGCGCGAGACGGGCCCCGTCG
ATCCCGGCGACGATCTCGCGTTCGGCAGCCTGCGCGCGCGCTGA

Upstream 100 bases:

>100_bases
AGTATAGGATTCACGCGTCCATAAATAAAATGACTTGGTTCTATAAAACCCATTCCGTTTAGGAATCTTCTCCGATTCGC
TCACTGAACAGGAGGCGCCG

Downstream 100 bases:

>100_bases
GCGCTTGGCCCGGGCGCGCCGCGCGCCCCATGCCCGGAGCGGGCCGGGCCGAGCGCCGCTCAGTGCCCGATCGCGGGCCC
GGCCCCTTTCTTCGGCTTCG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MELRALRYFVEVVRQQSFTVAAEQMHVTQPTISKMVKALEDEIGSPLLLRDGRQMVLTDAGRIVYQRGQDVLAAQAQLQA
ELNDLGTLGRGELTIGIPPLGGSLFTPAIAAFKERYPRIELKLFEQGARMIEEALVAGELELGGVLEPVDPAVFDVLPMV
RAPLWLVAPHASRWDGDATVPLADLADEPFVFYAESLALHDAVLDACRKVGFTPQIVSRSGHWDFMAALVHAGVGIALLP
EPYCRRLDTARFTCRPIVEPEITWAVAIGWLKRGYLSHAARAWLDVARETGPVDPGDDLAFGSLRAR

Sequences:

>Translated_307_residues
MELRALRYFVEVVRQQSFTVAAEQMHVTQPTISKMVKALEDEIGSPLLLRDGRQMVLTDAGRIVYQRGQDVLAAQAQLQA
ELNDLGTLGRGELTIGIPPLGGSLFTPAIAAFKERYPRIELKLFEQGARMIEEALVAGELELGGVLEPVDPAVFDVLPMV
RAPLWLVAPHASRWDGDATVPLADLADEPFVFYAESLALHDAVLDACRKVGFTPQIVSRSGHWDFMAALVHAGVGIALLP
EPYCRRLDTARFTCRPIVEPEITWAVAIGWLKRGYLSHAARAWLDVARETGPVDPGDDLAFGSLRAR
>Mature_307_residues
MELRALRYFVEVVRQQSFTVAAEQMHVTQPTISKMVKALEDEIGSPLLLRDGRQMVLTDAGRIVYQRGQDVLAAQAQLQA
ELNDLGTLGRGELTIGIPPLGGSLFTPAIAAFKERYPRIELKLFEQGARMIEEALVAGELELGGVLEPVDPAVFDVLPMV
RAPLWLVAPHASRWDGDATVPLADLADEPFVFYAESLALHDAVLDACRKVGFTPQIVSRSGHWDFMAALVHAGVGIALLP
EPYCRRLDTARFTCRPIVEPEITWAVAIGWLKRGYLSHAARAWLDVARETGPVDPGDDLAFGSLRAR

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=296, Percent_Identity=29.3918918918919, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=30.9027777777778, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1790399, Length=296, Percent_Identity=28.3783783783784, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=31.3131313131313, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=27.3092369477912, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=27.2, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=25.3521126760563, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788748, Length=302, Percent_Identity=29.4701986754967, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789506, Length=287, Percent_Identity=22.9965156794425, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787530, Length=268, Percent_Identity=25.3731343283582, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790208, Length=246, Percent_Identity=29.6747967479675, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693193, Length=123, Percent_Identity=34.1463414634146, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=142, Percent_Identity=34.5070422535211, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788296, Length=286, Percent_Identity=24.4755244755245, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787806, Length=242, Percent_Identity=24.3801652892562, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787601, Length=148, Percent_Identity=31.0810810810811, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789173, Length=122, Percent_Identity=30.327868852459, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33715; Mature: 33715

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRALRYFVEVVRQQSFTVAAEQMHVTQPTISKMVKALEDEIGSPLLLRDGRQMVLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECC
GRIVYQRGQDVLAAQAQLQAELNDLGTLGRGELTIGIPPLGGSLFTPAIAAFKERYPRIE
CHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEE
LKLFEQGARMIEEALVAGELELGGVLEPVDPAVFDVLPMVRAPLWLVAPHASRWDGDATV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCC
PLADLADEPFVFYAESLALHDAVLDACRKVGFTPQIVSRSGHWDFMAALVHAGVGIALLP
CHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCEEECC
EPYCRRLDTARFTCRPIVEPEITWAVAIGWLKRGYLSHAARAWLDVARETGPVDPGDDLA
CHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FGSLRAR
CCCCCCC
>Mature Secondary Structure
MELRALRYFVEVVRQQSFTVAAEQMHVTQPTISKMVKALEDEIGSPLLLRDGRQMVLTDA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCEEEEECC
GRIVYQRGQDVLAAQAQLQAELNDLGTLGRGELTIGIPPLGGSLFTPAIAAFKERYPRIE
CHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEE
LKLFEQGARMIEEALVAGELELGGVLEPVDPAVFDVLPMVRAPLWLVAPHASRWDGDATV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCC
PLADLADEPFVFYAESLALHDAVLDACRKVGFTPQIVSRSGHWDFMAALVHAGVGIALLP
CHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHCCCCEEECC
EPYCRRLDTARFTCRPIVEPEITWAVAIGWLKRGYLSHAARAWLDVARETGPVDPGDDLA
CHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FGSLRAR
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]