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The map label for this gene is 237814386

Identifier: 237814386

GI number: 237814386

Start: 4007772

End: 4008335

Strand: Reverse

Name: 237814386

Synonym: GBP346_A4184

Alternate gene names: NA

Gene position: 4008335-4007772 (Counterclockwise)

Preceding gene: 237814387

Following gene: 237814383

Centisome position: 97.8

GC content: 59.57

Gene sequence:

>564_bases
ATGCGCGGCGCGATCGTTTCAGTTTCAAGTCGTCTTCAAAGGATTCGTTCGATGAGTTCACGCAGGATCGTGGTACGCCG
CTCGGGCGTTCACGGCAAGGGCGTATTCGCCGCGGTACCGATCAAGGCGGGAGAGCGCGTAGTCGAATACAAGGGCGAGC
GGATCTCGTGGAAAGAGGCGCTGCGCCGCCATCCGCACGACCCGGACGATCCGAATCACACCTTTTACTTCGCGCTGGAA
GAGGGCGGGGTGATCGACGGCAAGATCGACGGCAACAGCGCGCGCTGGATCAACCATTCGTGCGCGCCGAACTGCGAAGC
CGAGGAAGTGGGCGGGCACGTGTACATCCATGCGCTGCGTGACATCGACGAGCAGGAAGAACTGTTCTACGACTACGGTC
TCGTGATCGACGCGCGCCTGACGAAAAAGCTCAAGCGCGAATACGTGTGCCATTGCGGCGCGGCGACGTGCCGCGGCACG
CTGCTTGCAACGTCGGAAGAAGACGAAGGCAAGAAAAAGAAGAAGGCGAAGAAAGGCGGCAAGGACAAGAAAAAGAAGAA
GTGA

Upstream 100 bases:

>100_bases
ATCCCGAACGTGTAGGATTCGATGATTCGCGCCCGGTGCCGCACGCGGCCTATGATGGCCGCCTGCGGCGCGACGGGCCA
AGCCGCGCGGCCGGCACGCA

Downstream 100 bases:

>100_bases
CGCCCGGCGGCGGTGCGCGGCAAGCTCGCGCGGCCGCCGCGGTTTCCCGGCGTTCGAATCGGCGTTCGAATCGAAGAAGG
CCGTCCCCGCGTTATTCCCT

Product: SET domain protein

Products: NA

Alternate protein names: Histone-Lysine N-Methyltransferase; SET Domain-Containing Protein; SET Domain Protein; Set Domain Protein; HistoNe-Lysine N-Methyltransferase H3 Lysine-4 Specific; Setd1a Protein; Nuclear Protein Set; Zinc Finger Protein

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRGAIVSVSSRLQRIRSMSSRRIVVRRSGVHGKGVFAAVPIKAGERVVEYKGERISWKEALRRHPHDPDDPNHTFYFALE
EGGVIDGKIDGNSARWINHSCAPNCEAEEVGGHVYIHALRDIDEQEELFYDYGLVIDARLTKKLKREYVCHCGAATCRGT
LLATSEEDEGKKKKKAKKGGKDKKKKK

Sequences:

>Translated_187_residues
MRGAIVSVSSRLQRIRSMSSRRIVVRRSGVHGKGVFAAVPIKAGERVVEYKGERISWKEALRRHPHDPDDPNHTFYFALE
EGGVIDGKIDGNSARWINHSCAPNCEAEEVGGHVYIHALRDIDEQEELFYDYGLVIDARLTKKLKREYVCHCGAATCRGT
LLATSEEDEGKKKKKAKKGGKDKKKKK
>Mature_187_residues
MRGAIVSVSSRLQRIRSMSSRRIVVRRSGVHGKGVFAAVPIKAGERVVEYKGERISWKEALRRHPHDPDDPNHTFYFALE
EGGVIDGKIDGNSARWINHSCAPNCEAEEVGGHVYIHALRDIDEQEELFYDYGLVIDARLTKKLKREYVCHCGAATCRGT
LLATSEEDEGKKKKKAKKGGKDKKKKK

Specific function: Unknown

COG id: COG2940

COG function: function code R; Proteins containing SET domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI56550039, Length=155, Percent_Identity=34.8387096774194, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI7662046, Length=155, Percent_Identity=35.4838709677419, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI91718902, Length=156, Percent_Identity=33.974358974359, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI110349788, Length=169, Percent_Identity=32.5443786982249, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI210032580, Length=140, Percent_Identity=35.7142857142857, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI148762969, Length=156, Percent_Identity=34.6153846153846, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI55741677, Length=166, Percent_Identity=31.3253012048193, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI19913358, Length=136, Percent_Identity=37.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19913350, Length=136, Percent_Identity=37.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19913348, Length=136, Percent_Identity=37.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109633019, Length=136, Percent_Identity=37.5, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI23510384, Length=130, Percent_Identity=37.6923076923077, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI197313748, Length=180, Percent_Identity=31.1111111111111, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI13699811, Length=168, Percent_Identity=33.9285714285714, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI13375930, Length=158, Percent_Identity=34.1772151898734, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI301171597, Length=158, Percent_Identity=34.1772151898734, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI301171588, Length=158, Percent_Identity=34.1772151898734, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI21361095, Length=130, Percent_Identity=37.6923076923077, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI19923586, Length=140, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=5e-11,
Organism=Homo sapiens, GI27477095, Length=140, Percent_Identity=35.7142857142857, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193210440, Length=155, Percent_Identity=32.9032258064516, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17552316, Length=156, Percent_Identity=33.974358974359, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17552320, Length=155, Percent_Identity=33.5483870967742, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17552318, Length=155, Percent_Identity=33.5483870967742, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25148426, Length=148, Percent_Identity=37.1621621621622, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25148423, Length=140, Percent_Identity=38.5714285714286, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71993684, Length=161, Percent_Identity=31.6770186335404, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17565204, Length=158, Percent_Identity=30.379746835443, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321911, Length=165, Percent_Identity=35.7575757575758, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI62472551, Length=163, Percent_Identity=31.2883435582822, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17136558, Length=163, Percent_Identity=31.2883435582822, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19550181, Length=163, Percent_Identity=31.2883435582822, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19550184, Length=163, Percent_Identity=31.2883435582822, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17136556, Length=163, Percent_Identity=31.2883435582822, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24641786, Length=153, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281360813, Length=153, Percent_Identity=35.2941176470588, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571451, Length=156, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639197, Length=156, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24650756, Length=164, Percent_Identity=33.5365853658537, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17737643, Length=154, Percent_Identity=33.1168831168831, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21031; Mature: 21031

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50280 SET ; PS50868 POST_SET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGAIVSVSSRLQRIRSMSSRRIVVRRSGVHGKGVFAAVPIKAGERVVEYKGERISWKEA
CCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCEEEECCCCEECHHHH
LRRHPHDPDDPNHTFYFALEEGGVIDGKIDGNSARWINHSCAPNCEAEEVGGHVYIHALR
HHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCHHHCCCEEEEEEEC
DIDEQEELFYDYGLVIDARLTKKLKREYVCHCGAATCRGTLLATSEEDEGKKKKKAKKGG
CCCHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCHHHCCEEEECCCCHHHHHHHHHHCCC
KDKKKKK
CCCCCCC
>Mature Secondary Structure
MRGAIVSVSSRLQRIRSMSSRRIVVRRSGVHGKGVFAAVPIKAGERVVEYKGERISWKEA
CCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCEEEECCCCEECHHHH
LRRHPHDPDDPNHTFYFALEEGGVIDGKIDGNSARWINHSCAPNCEAEEVGGHVYIHALR
HHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCHHHCCCEEEEEEEC
DIDEQEELFYDYGLVIDARLTKKLKREYVCHCGAATCRGTLLATSEEDEGKKKKKAKKGG
CCCHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCHHHCCEEEECCCCHHHHHHHHHHCCC
KDKKKKK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA