| Definition | Burkholderia pseudomallei MSHR346 chromosome I, complete genome. |
|---|---|
| Accession | NC_012695 |
| Length | 4,098,576 |
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The map label for this gene is livF [H]
Identifier: 237814359
GI number: 237814359
Start: 3984893
End: 3985648
Strand: Reverse
Name: livF [H]
Synonym: GBP346_A4157
Alternate gene names: 237814359
Gene position: 3985648-3984893 (Counterclockwise)
Preceding gene: 237814360
Following gene: 237814358
Centisome position: 97.24
GC content: 61.77
Gene sequence:
>756_bases ATGGATCGAGAGGCGAAGCCGGTGTTGGCGGTACAGAATCTGTCGGTGCGCTACGGCAAGGTCGAGGCGTTGCATCGTGC GGCCCTGACGGTCGGAGCAGGGCAGATCGTCACAGTGATTGGGCCGAACGGGGCGGGAAAGTCGACGCTGCTCAATGCGG TGATGGGCGCGTTGCCGACGAATGGCCATGCTACCGGTACGGTTCTTTACCGCGGCGACGATGTGGATGCATTGCCGGTC GAGCAGCGTGTCGCGCTCGGTATGTGCCTCGTGCCGGAAAAGCGTGAGCTATTCGGCACGATGTCGGTAGAGGACAATTT GGTGTTAGGCGCATACCGGCGAAAGATGGCCGGCGACGCGAGCTTCCTGGATCAGCTCGAGCCGGTTTTTTCGCTGTTTC CGAGGTTGAAGGAGCGACGCAAGCAAGCGGCCGGCACGCTTTCGGGTGGCGAGCGGCAGATGCTGGCTGTCGGGCGCGCG CTGATGGGCAAACCCGATTTGCTGATGCTCGACGAGCCGAGCCTTGGGCTTGCACCGCTGATCGTGAAGGAGATTTTCCA TATCATCAGCGCGCTGCGCGGGACCGGCGTTGCGATGCTGTTGATCGAGCAGAACGCGCGGGCAGCATTGCAGATATCGG ATTACGGGTATGTCCTCGAGACCGGTGAGATTGCTCTGGAGGGCCCGGCGGGCGAACTCGCGCAGAATCCGCAAGTGATC GAAACCTACCTGGGGCTCGCAAGAAAGGCGGTCTAG
Upstream 100 bases:
>100_bases TCGTGATGGAGTTCGGTACGCGGATCGCCGAAGGCTTGCCACAGGATGTGCAGAAGGATCCGGCAGTGCTGGAAGCCTAT CTCGGTGGGGTGGAGTGATG
Downstream 100 bases:
>100_bases CAGGGGCTCCGCTGGTTCCGGTCGACGGCGTGTTTCACGTGAAACACGCCGTTTTTTATGGTCGGCCGTTCGAACAAGAT TCGGGCCAAAACCGAACCCG
Product: branched-chain amino acid ABC transporter, ATP-binding protein
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 251; Mature: 251
Protein sequence:
>251_residues MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPTNGHATGTVLYRGDDVDALPV EQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDASFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVAMLLIEQNARAALQISDYGYVLETGEIALEGPAGELAQNPQVI ETYLGLARKAV
Sequences:
>Translated_251_residues MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPTNGHATGTVLYRGDDVDALPV EQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDASFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVAMLLIEQNARAALQISDYGYVLETGEIALEGPAGELAQNPQVI ETYLGLARKAV >Mature_251_residues MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPTNGHATGTVLYRGDDVDALPV EQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDASFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVAMLLIEQNARAALQISDYGYVLETGEIALEGPAGELAQNPQVI ETYLGLARKAV
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27262624, Length=178, Percent_Identity=29.7752808988764, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI27262626, Length=178, Percent_Identity=29.7752808988764, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI27436953, Length=234, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI47078218, Length=230, Percent_Identity=29.5652173913043, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI105990541, Length=228, Percent_Identity=29.8245614035088, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI45446740, Length=230, Percent_Identity=29.5652173913043, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI27477115, Length=235, Percent_Identity=30.2127659574468, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI27881501, Length=215, Percent_Identity=27.4418604651163, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI30795238, Length=215, Percent_Identity=27.4418604651163, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI153792144, Length=184, Percent_Identity=33.695652173913, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI21536376, Length=245, Percent_Identity=27.3469387755102, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI31657092, Length=202, Percent_Identity=27.2277227722772, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI148612844, Length=223, Percent_Identity=29.5964125560538, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI255708477, Length=223, Percent_Identity=29.5964125560538, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592971, Length=207, Percent_Identity=25.6038647342995, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592898, Length=207, Percent_Identity=25.6038647342995, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592956, Length=207, Percent_Identity=25.6038647342995, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592964, Length=208, Percent_Identity=25.4807692307692, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592978, Length=207, Percent_Identity=25.6038647342995, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI46592915, Length=207, Percent_Identity=25.6038647342995, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI11967969, Length=243, Percent_Identity=26.7489711934156, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI116734710, Length=213, Percent_Identity=26.7605633802817, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI87082268, Length=241, Percent_Identity=45.643153526971, Blast_Score=208, Evalue=3e-55, Organism=Escherichia coli, GI1789864, Length=257, Percent_Identity=31.9066147859922, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1789593, Length=237, Percent_Identity=31.6455696202532, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI1787792, Length=257, Percent_Identity=29.5719844357977, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1790162, Length=242, Percent_Identity=28.9256198347107, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789672, Length=241, Percent_Identity=28.2157676348548, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787029, Length=240, Percent_Identity=26.6666666666667, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI1790190, Length=213, Percent_Identity=31.4553990610329, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1788053, Length=173, Percent_Identity=36.4161849710983, Blast_Score=88, Evalue=4e-19, Organism=Escherichia coli, GI1788472, Length=230, Percent_Identity=29.5652173913043, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87081782, Length=237, Percent_Identity=31.6455696202532, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI87081709, Length=254, Percent_Identity=27.5590551181102, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI48994943, Length=237, Percent_Identity=30.379746835443, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1787370, Length=227, Percent_Identity=26.8722466960352, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI87081791, Length=232, Percent_Identity=26.2931034482759, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789991, Length=225, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=25.3218884120172, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=29.0748898678414, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787089, Length=239, Percent_Identity=28.0334728033473, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1790525, Length=247, Percent_Identity=25.9109311740891, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1788897, Length=232, Percent_Identity=28.8793103448276, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1790467, Length=237, Percent_Identity=30.8016877637131, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1786872, Length=237, Percent_Identity=27.0042194092827, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1786398, Length=231, Percent_Identity=28.1385281385281, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786698, Length=209, Percent_Identity=32.0574162679426, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1789586, Length=248, Percent_Identity=28.2258064516129, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI48995001, Length=249, Percent_Identity=28.1124497991968, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787105, Length=246, Percent_Identity=27.6422764227642, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=28.8990825688073, Blast_Score=74, Evalue=6e-15, Organism=Escherichia coli, GI1787712, Length=222, Percent_Identity=30.1801801801802, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=30.622009569378, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI87081834, Length=219, Percent_Identity=27.8538812785388, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787759, Length=252, Percent_Identity=25.7936507936508, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1788450, Length=227, Percent_Identity=26.431718061674, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1786319, Length=223, Percent_Identity=30.4932735426009, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1790544, Length=265, Percent_Identity=23.0188679245283, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI48994883, Length=247, Percent_Identity=25.1012145748988, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI87082267, Length=163, Percent_Identity=31.9018404907975, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1790739, Length=247, Percent_Identity=25.5060728744939, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788644, Length=247, Percent_Identity=27.9352226720648, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788165, Length=245, Percent_Identity=26.530612244898, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789032, Length=225, Percent_Identity=28.4444444444444, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1786975, Length=205, Percent_Identity=26.8292682926829, Blast_Score=62, Evalue=2e-11, Organism=Escherichia coli, GI1788506, Length=256, Percent_Identity=24.609375, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787164, Length=221, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI145693107, Length=256, Percent_Identity=25.78125, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1786803, Length=251, Percent_Identity=23.5059760956175, Blast_Score=60, Evalue=9e-11, Organism=Caenorhabditis elegans, GI71983523, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71983516, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71983510, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17510237, Length=217, Percent_Identity=26.7281105990783, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17565586, Length=177, Percent_Identity=31.638418079096, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI193208177, Length=236, Percent_Identity=27.5423728813559, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI115532730, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI115533608, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17539902, Length=210, Percent_Identity=27.1428571428571, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322640, Length=222, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=8e-12, Organism=Drosophila melanogaster, GI221512771, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24666092, Length=215, Percent_Identity=28.3720930232558, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI28574533, Length=245, Percent_Identity=27.3469387755102, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24643674, Length=222, Percent_Identity=25.2252252252252, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI28574150, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007328, Length=202, Percent_Identity=27.2277227722772, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI19920532, Length=215, Percent_Identity=27.4418604651163, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24580930, Length=215, Percent_Identity=27.4418604651163, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI28573573, Length=227, Percent_Identity=25.9911894273128, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28573571, Length=227, Percent_Identity=25.9911894273128, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24662800, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28574744, Length=204, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24650853, Length=260, Percent_Identity=25, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24650855, Length=260, Percent_Identity=25, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24648314, Length=230, Percent_Identity=25.6521739130435, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI85816269, Length=207, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24580553, Length=207, Percent_Identity=24.6376811594203, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI85724864, Length=207, Percent_Identity=24.6376811594203, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24580555, Length=207, Percent_Identity=24.6376811594203, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI17136592, Length=218, Percent_Identity=26.605504587156, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI28571209, Length=255, Percent_Identity=27.0588235294118, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI161076682, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI161076684, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24581617, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24581615, Length=202, Percent_Identity=26.7326732673267, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI281362751, Length=260, Percent_Identity=25, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26756; Mature: 26756
Theoretical pI: Translated: 6.81; Mature: 6.81
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPT CCCCCCCEEEEECCEEEHHHHHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHCCC NGHATGTVLYRGDDVDALPVEQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDA CCCCEEEEEEECCCCCCCCHHHHHHHCEEECCCHHHHEEECCCCCCEEEHHHHHHHCCCH SFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRALMGKPDLLMLDEPSLGLAPL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHH IVKEIFHIISALRGTGVAMLLIEQNARAALQISDYGYVLETGEIALEGPAGELAQNPQVI HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCEEEECCCEEEECCCCHHHCCCHHH ETYLGLARKAV HHHHHHHHHCC >Mature Secondary Structure MDREAKPVLAVQNLSVRYGKVEALHRAALTVGAGQIVTVIGPNGAGKSTLLNAVMGALPT CCCCCCCEEEEECCEEEHHHHHHHHHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHCCC NGHATGTVLYRGDDVDALPVEQRVALGMCLVPEKRELFGTMSVEDNLVLGAYRRKMAGDA CCCCEEEEEEECCCCCCCCHHHHHHHCEEECCCHHHHEEECCCCCCEEEHHHHHHHCCCH SFLDQLEPVFSLFPRLKERRKQAAGTLSGGERQMLAVGRALMGKPDLLMLDEPSLGLAPL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHH IVKEIFHIISALRGTGVAMLLIEQNARAALQISDYGYVLETGEIALEGPAGELAQNPQVI HHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCCEEEECCCEEEECCCCHHHCCCHHH ETYLGLARKAV HHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]