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The map label for this gene is ybdL [H]

Identifier: 237814328

GI number: 237814328

Start: 3951250

End: 3952404

Strand: Reverse

Name: ybdL [H]

Synonym: GBP346_A4126

Alternate gene names: 237814328

Gene position: 3952404-3951250 (Counterclockwise)

Preceding gene: 237814329

Following gene: 237814327

Centisome position: 96.43

GC content: 69.52

Gene sequence:

>1155_bases
ATGCAGAGCGCCGCCGCGCCCCGTTCGAAGCTGCCCGACGTCGGCACGACGATCTTCACGGTCATCGGCCAGCTCGCCGC
CGAGCACGAGGCGCTGAATCTGTCGCAGGGCGCGCCGAATTTCGCGCCCGATCCGGCGCTCGTCGAGCGCGTCGCCCGCG
CGATGCGAGACGGGCACAACCAGTACGCGCCGATGGCGGGCATCGCCGCGCTGCGCGAGGCGCTCGCCGTGAAGACCGAG
CGCCTGTACGGCGAGCGCTACGATCCGGACTCCGAAGTCACCGTCGTCGCGAGCGCGAGCGAGGGGCTCTACGCGGCGAT
CAGCGCGCTCGTCCATCCGGGCGACGAGGTGATCTACTTCGAGCCGTCGTTCGACAGCTACGCGCCGATCGTCCGGCTGC
AGGGCGCGACGCCCGTCGCGATCAGGCTGTCGCCCGAGCGCTTTCGCGTGAACTGGGACGAGGTGGCCGCGAAGATCACG
CCGCGCACGCGGATGCTGATCGTCAACACGCCGCACAACCCGAGCGCGACGATCCTCGGCGAGGCCGACGTCGCGCGTCT
CGCGCAGCTCGTCGCGGGCACCGACATCGTGGTGCTGTCCGACGAGGTGTACGAGCACGTCGTGTTCGACGGCGCGCGCC
ATCACAGCATGGCGCGCGATCGCGCGCTCGCCGAGCGCAGCGTGATCGTGTCGTCGTTCGGCAAGTCGTATCACGTGACG
GGCTGGCGCGTCGGCTACTGCCTCGCGCCCGCCGAGCTCACGCGCGAGCTGCGCAAGGTCCATCAGTTCATGACGTTCGC
GGCCGATACGCCGATGCAGCATGCGTTCGCGGCGGCGCTCGCGGAGCCGGCGAGCTATCTCGAGCTCGGCGCGTTCTACG
AGCGCAAGCGCGACCTGCTCGTGCGCGAGCTGGCCGGCTCGCGCTTCGAGCTGCTGCCGAGCGAGGGCTCGTTCTTCATG
CTCGCGCGCTTCGGGCATTTTTCGGACGAATCGGACGCCGACTTCGTGCTGCGTGCGATTCGCGACGCACGCGTCGCGAC
GATTCCGCTGTCCGCGTTCTACGCGGACGGCGCGAACACCGGCTGCATCCGTTTGAGCTTTTCGAAGGACGACGCGACGC
TCGTCGAAGGCGCGCGCCGCTTGTGCAGCCTCTGA

Upstream 100 bases:

>100_bases
AACTTTCGATTGCCGCCGGATATTGGCTCGGGCCCAATCCGCATCGTTGCCCCGCGCGCCGGCGATGGCCGCGCGCCCGT
TCACGAGCCCAGGAGGATCC

Downstream 100 bases:

>100_bases
CGCGCGCGGTGCCCGCCGCTGCGGACATGACCCGATCTCAAGGAGAAACATCGATGAAACGATTGCAATTCTGGTTCGCG
CTCGCCTGTGCATTGGGCGC

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIAALREALAVKTE
RLYGERYDPDSEVTVVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRFELLPSEGSFFM
LARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL

Sequences:

>Translated_384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIAALREALAVKTE
RLYGERYDPDSEVTVVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRFELLPSEGSFFM
LARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL
>Mature_384_residues
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHNQYAPMAGIAALREALAVKTE
RLYGERYDPDSEVTVVASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKIT
PRTRMLIVNTPHNPSATILGEADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLLVRELAGSRFELLPSEGSFFM
LARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANTGCIRLSFSKDDATLVEGARRLCSL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=33.419689119171, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=33.419689119171, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=30.3030303030303, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI56713256, Length=392, Percent_Identity=30.6122448979592, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI169881281, Length=384, Percent_Identity=28.90625, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.8726790450928, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=53.0343007915567, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1788722, Length=337, Percent_Identity=26.1127596439169, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=339, Percent_Identity=25.3687315634218, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=412, Percent_Identity=31.5533980582524, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71994476, Length=412, Percent_Identity=31.5533980582524, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17567369, Length=409, Percent_Identity=28.6063569682152, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17567663, Length=337, Percent_Identity=24.0356083086053, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=28.4615384615385, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI28573069, Length=393, Percent_Identity=32.0610687022901, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24646114, Length=393, Percent_Identity=32.0610687022901, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI28573067, Length=393, Percent_Identity=32.0610687022901, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI28573065, Length=393, Percent_Identity=32.0610687022901, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 41956; Mature: 41956

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGIAALREALAVKTERLYGERYDPDSEVTVVASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKITPRTRMLIVNTPHNPSATILG
CCCCCCCCCEEEECCCCEEEEEECHHHHCCCHHHHHHEECCCEEEEEEECCCCCCEEEEC
EADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
CHHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLL
EEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VRELAGSRFELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANT
HHHHCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEHHHEECCCCCC
GCIRLSFSKDDATLVEGARRLCSL
CEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSAAAPRSKLPDVGTTIFTVIGQLAAEHEALNLSQGAPNFAPDPALVERVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGIAALREALAVKTERLYGERYDPDSEVTVVASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIRLSPERFRVNWDEVAAKITPRTRMLIVNTPHNPSATILG
CCCCCCCCCEEEECCCCEEEEEECHHHHCCCHHHHHHEECCCEEEEEEECCCCCCEEEEC
EADVARLAQLVAGTDIVVLSDEVYEHVVFDGARHHSMARDRALAERSVIVSSFGKSYHVT
CHHHHHHHHHHCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
GWRVGYCLAPAELTRELRKVHQFMTFAADTPMQHAFAAALAEPASYLELGAFYERKRDLL
EEEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VRELAGSRFELLPSEGSFFMLARFGHFSDESDADFVLRAIRDARVATIPLSAFYADGANT
HHHHCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEHHHEECCCCCC
GCIRLSFSKDDATLVEGARRLCSL
CEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]