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The map label for this gene is cadR [H]

Identifier: 237814322

GI number: 237814322

Start: 3948221

End: 3948652

Strand: Direct

Name: cadR [H]

Synonym: GBP346_A4120

Alternate gene names: 237814322

Gene position: 3948221-3948652 (Clockwise)

Preceding gene: 237814317

Following gene: 237814323

Centisome position: 96.33

GC content: 62.73

Gene sequence:

>432_bases
ATGAAGATCGGCGAACTGGCGAAAGCGGCGCGGTGCACGCCGGAAACGATTCGCTTCTATGAAAAAGAGGGGCTGATGCC
CGACGCGGAACGGACCGATTCCAACTACCGCCACTACACCGACGCGCACGTCGAGCGGCTGCGCTTCATCCGCAACTGCC
GCGCGCTCGACATGACGCACGATGAAATCCGCGCACTGCTGCGCTTCACCGACGACCCGGCGGACCGCTGCGATTCGGTC
AACGCGCTGCTCGACGAACACATCGGCCACGTCAACACGCGGCTTGCCGAACTGCAGCATTTGCGCATGCAATTGATCGA
ATTGCGCGAACGGTGCCAGGGCGAGCACGCAGTCGAGGATTGCGGAATCGTGCATGGCCTCTCGACGATGGAAACGCCGG
ACATGCCCGGCAAACGCTCGCACGTCGGCTGA

Upstream 100 bases:

>100_bases
CCGGGTGGCCTCGGTCATGGCAACCTCCTCAGTAACTGACGGTGTACAGTTAACACCTTGTAGTCACTACAAGGTCAACT
CTTTTTGTAAGGAGATTCGA

Downstream 100 bases:

>100_bases
CGCGCAAGCCGCGTCACGCCCGGCCGACGGGCGCAACACGGCTTGCGTTCTTTTATATCTAGTCATATTATTTCTAGATA
ATAATTGACTAATCATGTTA

Product: Cd(II)/Pb(II)-responsive transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRHYTDAHVERLRFIRNCRALDMTHDEIRALLRFTDDPADRCDSV
NALLDEHIGHVNTRLAELQHLRMQLIELRERCQGEHAVEDCGIVHGLSTMETPDMPGKRSHVG

Sequences:

>Translated_143_residues
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRHYTDAHVERLRFIRNCRALDMTHDEIRALLRFTDDPADRCDSV
NALLDEHIGHVNTRLAELQHLRMQLIELRERCQGEHAVEDCGIVHGLSTMETPDMPGKRSHVG
>Mature_143_residues
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRHYTDAHVERLRFIRNCRALDMTHDEIRALLRFTDDPADRCDSV
NALLDEHIGHVNTRLAELQHLRMQLIELRERCQGEHAVEDCGIVHGLSTMETPDMPGKRSHVG

Specific function: Transcriptional regulator [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=128, Percent_Identity=39.0625, Blast_Score=91, Evalue=2e-20,
Organism=Escherichia coli, GI1786695, Length=128, Percent_Identity=32.03125, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16481; Mature: 16481

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRHYTDAHVERLRFIRNCRALDMTH
CCHHHHHHHHCCCHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
DEIRALLRFTDDPADRCDSVNALLDEHIGHVNTRLAELQHLRMQLIELRERCQGEHAVED
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
CGIVHGLSTMETPDMPGKRSHVG
HHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIGELAKAARCTPETIRFYEKEGLMPDAERTDSNYRHYTDAHVERLRFIRNCRALDMTH
CCHHHHHHHHCCCHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
DEIRALLRFTDDPADRCDSVNALLDEHIGHVNTRLAELQHLRMQLIELRERCQGEHAVED
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
CGIVHGLSTMETPDMPGKRSHVG
HHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]